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Research Article

A Microsphere-Liposome (Microplex) Vector for Targeted Gene Therapy of Cancer. II. In Vivo Biodistribution Study in a Solid Tumor Model

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Pages 15-19 | Published online: 29 Sep 2008

References

  • Alexakis, T., Boadi, D. K., Quong, D., Groboillot, A., O’Neill, I., Poncelet, D., and Neufeld, R. J. 1995. Microencapsulatio n of DNA within alginate microsphere s and cross-linked chitosan membranes for in vivo application. Appl. Biochem. Biotechnol. 50:93–106.
  • Anderson, J. H., Angerson, W. J., Willmott, N., Kerr, D. J., McArdle, C. S., and Cooke, T. G. 1991. Regional distribution of microspheres to liver metastase: The effects of particle size and concentratio n on intrahepatic distribution. Br. J. Cancer 64:1031–1034.
  • Barnes, M. N., DeShane, J. S., Rosenfeld, M., Siegal, G. P., Curiel, D. T., and Alvarez, R. D. 1997. Gene therapy and ovarian cancer: A review. Obstet. Gynecol. 89:145–155.
  • Bertling, W. M., Gareis, M., Paspaleeva, V., Zimmer, A., Kreuter, J., Nurnberg, E., and Harrer, P. 1991. Use of liposomes, viral capsids, and nanoparticle s as DNA carriers. Biotechnol. Appl. Biochem. 13:390–405.
  • Boucher, R. C. 1996. Current status of CF gene therapy. Trends in Genetics 12:81–84.
  • Cortesi, R., Esposito, E., Menegatti, E., Gambari, R., and Nastruzzi, C. 1994. Gelatin microsphere s as a new approach for the controlled delivery of syn- thetic oligonucleotide s and PCR-generated DNA fragments. Int. J. Pharma- ceutics 105:181–186.
  • Dass, C. R. 1998. Targeted delivery of DNA for cancer therapy, PhD thesis, Charles Sturt University, New South Wales, Australia.
  • Dass, C. R., Walker, T. L., DeCruz, E. E., and Burton, M. A. 1996a. In vitro evaluation of ion-exchang e microsphere s as carriers of plasmid DNA. Pharm. Sci. 2:401–405.
  • Dass, C. R., Walker, T. L., Burton, M. A., and DeCruz, E. E. 1996b. Spectropho- tometric method for quantitation of cationic liposomes. Aust. J. Hosp. Pharm. 26:S42–43.
  • Dass, C. R., Walker, T. L., Burton, M. A., and DeCruz, E. E. 1997a. Enhanced anticancer therapy mediated by specialized liposomes. J. Pharm. Pharmacol. 49:972–975.
  • Dass, C. R., DeCruz, E. E., Walker, T. L., and Burton, M. A. 1997b. Limitation of lipoplexes for gene therapy of solid tumours. Aust. Pharm. Sci. Assoc. Conf. Proc. Sydney, p. 39.
  • Dass, C. R., DeCruz, E. E., Walker, T. L., and Burton, M. A. 1997c. Tumour gene-targetin g using microspheres: Cell culture and in vivo studies. Drug Delivery 4:263–267.
  • Dass, C. R., Walker, T. L., DeCruz, E. E., and Burton, M. A. 1997d. Cationic liposomes and gene therapy for solid tumours. Drug Delivery 4:151–166. Esdale, W. J., Walker, T. L., White, J., DeCruz, E. E., and Burton, M. A. 1997. The eficacy of doxorubici n microspheres for hepatic micrometastases in a rat tumour model. Clin. Exp. Metastasis 15:239–245.
  • Friend, D. S., Papahadjopoulos, D., and Debs, R. J. 1996. Endocytosi s and intracellular processing accompanyin g transfection mediated by cationic li- posomes. Biochim. Biophys. Acta—Biomembrane s 1278:41–50.
  • Gray, B. N., Burton, M. A., Kelleher, D. K., Anderson, J., and Klemp, P. 1989. Selective internal radiation (SIR) therapy for treatment of liver metastases: Measurement of response rates. J. Surg. Oncol. 42:192–196.
  • Ledley, F. D. 1995. Nonviral gene therapy: The promise of genes as pharma- cuetical products. Human Gene Ther. 6:1129–1144.
  • Lew, D., Parker, S. E., Latimer, T., Abai, A. M., Kuwahara-Rundell, A., Doh, S. G., Yang, Z., Laface, D., Gromkowski, S. H., Nabel, G. J., Manthorpe, M., and Norman, J. 1995. Cancer gene therapy using plasmid DNA: Phar- macokinetic study of DNA following injection in mice. Human Gene Ther. 6:553–564.
  • Mathiowitz, E., Jacob, J. S., Jong, Y. S., Carino, G. P., Chickering, D. E., Chaturvedi, P., Santos, C. A., Vijayaraghavan, K., Montgomer y. S., Bassett, M., and Morrell, C. 1997. Biologically erodable microspheres as potential oral drug delivery systems. Nature 386:410–414.
  • Meade, V. M., Burton, M. A., Gray, B. N., and Self, G. W. 1987. Distribution of different sized microspheres in experimenta l hepatic tumours. Eur. J. Cancer Clin. Oncol. 23:37–41.
  • Moghimi, S. M., Porter, C. J. H., Muir, I. S., Illum, L., and Davis, S. S. 1991. Nonphagocyti c uptake of intravenousl y injected microspheres in rat spleen: Influence of particle and hydrophilic coating. Biochem. Biophys. Res. Com- mun. 177:861–866.
  • Murray, J. C., and Carmichael, J. 1995. Targeting solid tumours: Challenges, disappointments, and opportunities. Adv. Drug Delivery Rev. 17:117–127.
  • Napoli, S., Burton, M. A., Martins, I. J., Chen, Y., Codde, J. P., and Gray, B. N. 1992. Dose response and toxicity of doxorubici n microspheres in a rat tumour model. Anti-Cancer Drugs 3:47–53.
  • Nishi, T., Yoshizato, K., Yamashiro, S., Takeshima, H., Sato, K., Hamada, K., Kitamura, I., Yoshimura, T., Saya, H., Kuratsu, J., and Ushio, Y. 1996. High- eficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation. Cancer Res. 56:1050–1055.
  • Smith, P. J. 1993. Into statistics. Nelson: Melbourne, pp. 348–354.
  • Teder, H., and Johansson, C. J. 1993. The effect of different dosages of degradabl e starch microsphere s (SpherexR) on the distribution of doxorubici n regionally administered to the rat. Anticancer Res. 13:2161–2164.
  • Toloza, E. M., Hunt, K., Miller, A. R., McBride, W., Lau, R., Swisher, S., Rhoades, K., Arthur, J., Choi, J., Chen, L., Chang, P., Chen, A., Glaspy, J., and Economou, J. S. 1997. Transduction of murine and human tumours using recombinant adenoviru s vectors. Ann. Surg. Oncol. 4:70–79.
  • UKCCCR. 1998. United Kingdom Co-ordinating Committee on Cancer Re- search guidelines for the welfare of animals in experimental neoplasia (2nd ed.). Br. J. Cancer 77:1–10.
  • Zavgorodni, S. F. 1996. A model for dose estimation in therapy of liver with intraarterial microspheres. Phys. Med. Biol. 41:2463–2480.

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