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Drug Delivery Volume 12, 2005 - Issue 4
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Research Article

Formulation and Evaluation of Alendronate Sodium Gel for the Treatment of Bone Resorptive Lesions in Periodontitis

G. Thirumal Reddy Department of Pharmaceutics, J.S.S. College of Pharmacy, MysoreIndia
,
T. M. Pramod Kumar Department of Pharmaceutics, J.S.S. College of Pharmacy, MysoreIndia
&
K. M. Veena Department of Periodontia, J.S.S. Dental College & Hospital, MysoreIndia
Pages 217-222 | Received 06 Aug 2004, Accepted 20 Oct 2004, Published online: 10 Oct 2008

REFERENCES

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  • Harvey, et al, United States Patent No. 6, 331, 533 (18 Dec. 2001)., 2001, Method for inhibiting dental resorptive lesions, 1–81
  • Haydee B. F. Use of β-cyclodextrins to prevent modifications of the properties of carbopol gels due to carbopol-drug interaction. Chem. Pharm. Bulletin 2002; 50: 40–46, [CROSSREF], [CSA]
  • Jernberg G. R., United States Patent No. 6, 123, 957 (16 July 1997), 1997, Delivery of agents and method for regeneration of periodontal tissue, 1–12
  • Jiunn H., Lin, et al. Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate in laboratory animals. J. Drug Metabol. Dispos. 1991; 926–932, [CSA]
  • Merck Sharp and Dohme (Italy). 2000; 1–14, Profile on alendronate sodium. Reg. No. Mal 1005100350A
  • Meyyanathan S. N., Ramasharma G. V. S. Quantitative determination of alendronate sodium in pharmaceutical dosage form and in bulk drug by spectrophotometry. Ind. Drugs 2001; 38: 461–463
  • Paulocosta J. M. S. L. Modeling and comparison of dissolution profiles. Eur. J. Pharm. Sci. 2001; 13: 123–133, [CROSSREF], [CSA]
  • Tenenbaum H. C. Bisphosphonates and periodontics: Potential applications for regulations of bone mass in the periodontium and other therapeutics/ diagnostic uses. J. Periodon. 2002; 73: 813–822, [CROSSREF]
  • Yaffe A., Miztkovich. Local delivery of an amino bisphosphonate prevents the resorptive phase of alveolar bone following mucoperiosteal flap surgery in Rats. J. Periodon. Sep. 1997; 68: 884–889

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