Advanced search
Publication Cover
Drug Delivery Volume 14, 2007 - Issue 8
Submit an article Journal homepage
933
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Preparation and Characterisation of Phenytoin-Loaded Alginate and Alginate-Chitosan Microparticles

Nebojša D. Cekié DCP Hemigal, Leskovac, Serbia
,
Snežana D. Savić Institute of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, Belgrade, Serbia
,
Jela Milić Institute of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, Belgrade, Serbia
,
Miroslav M. Savić Department of Pharmacology, Faculty of Pharmacy, Belgrade, Serbia
,
Žarko Jović Medicines and Medical Devices Agency of Serbia, Belgrade, Serbia
&
Marija Malešević Medicines and Medical Devices Agency of Serbia, Belgrade, Serbia
Pages 483-490 | Received 27 Nov 2006, Accepted 15 Jan 2007, Published online: 10 Oct 2008

REFERENCES

  • Buthe A., Hartmeier W., Ansorge-Schumacher M. B. Novel solvent-based method for preparation of alginate beads with improved roundness and predictable size. J. Microencapsul. 2004; 21: 865–876
  • Gaserod O., Sannes A., Skjak-Braek G. Microcapsules of alginate-chitosan. II. A study of capsule stability and permeability. Biomaterials 1999; 20: 773–783
  • Gasserod O., Smidsrod O., Skjak-Braek G. Microcapsules of alginate-chitosan. I. A quantitative study of the interaction between alginate and chitosan. Biomaterials 1998; 19: 1815–1825
  • Huguet M. L., Neufeld R. J., Dellacherie E. Calcium-alginate beads coated with polycationic polymers: comparison of chitosan and DEAE-dextran. Process Biochem. 1996; 39: 347–353
  • Huguet M. L., Groboillot A., Neufeldt R. J., Poncelet D., Dellacherie E. Haemoglobin encapsulation in chitosan/calcium alginate beads. J. Appl. Polym. Sci. 1994; 51: 1427–1432
  • Kas H. S. Chitosan: properties, preparation and application to microparticulate systems. J. Microencapsul. 1997; 14: 689–711
  • Kato Y., Onishi H., Machida Y. Application of chitin and chitosan derivatives in the pharmaceutical field. Curr. Pharm. Biotechn. 2003; 14: 303–309
  • Lee K. Y., Park W. H., Ha W. S. Polyelectrolyte complexes of sodium alginate with chitosan or its derivatives for microcapsules. J. Appl. Polym. Sci. 1997; 63: 425–432
  • Lim F., Sun A. M. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980; 210: 908–910
  • McDowell R. H. Properties of Alginates, 5th ed. Kelco International, London 1986
  • Murata Y., Nakada K., Miyamoto E., Kawashima S., Seo S. H. Influence of erosion of calcium-induced alginate gel matrix on the release of brilliant blue. J. Control. Rel. 1993; 23: 21–26
  • Ostberg T., Lund E. M., Graffner C. Calcium alginate matrices for oral multiple unit administration: IV. Release characteristics in different media. Int. J. Pharm. 1994; 112: 241–248
  • Overgaard S., Scharer J. M., Moo-Young M., Bols N. C. Immobilization of hybridoma cells in chitosan alginate beads. Can. J. Chem. Eng. 1991; 69: 439–443
  • Pellock J. M., Smith M. C., Cloyd J. C., Uthman B., Wilder B. J. Extended-release formulations: simplifying strategies in the management of antiepileptic drug therapy. Epilepsy Behav. 2004; 5: 301–307
  • Polk A., Amsden B., De Yao K., Peng T., Goosena A. Controlled release of albumin from chitosan-alginate microcapsules. J. Pharm. Sci. 1994; 83: 178–185
  • Roberts G. A. F. Introduction of chitin and chitosan. Chitin Chemistry, G. A. F. Roberts. The Macmillan Press Ltd., London 1992; 1–49
  • Sankalia M. G., Mashru R. C., Sankalia J. M., Sutariya V. B. Papain entrapment in alginate beads for stability improvement and site-specific delivery: physicochemical characterization and factorial optimization using neural network, modeling. AAPS Pharm. Sci. Tech. 2005; 6: 209–222
  • Sezer A. D., Akbuga J. Release characteristics of chitosan treated alginate beads: I. Sustained release of a macromolecular drug from chitosan treated alginate beads. J. Microencapsul 1999a; 16: 195–203
  • Sezer A. D., Akbuga J. Release characteristics of chitosan treated alginate beads: II. Sustained release of a low molecular drug from chitosan treated alginate beads. J. Microencapsul 1999b; 16: 687–696
  • Singla A. K., Chawla M. Chitosan: some pharmaceutical and biological aspects—an update. J. Pharm. Pharmacol. 2001; 53: 1047–1067
  • Sinha V. R., Singla A. K., Wadhawan S., Kaushik R., Kumria R., Bansal K., Dhawan S. Chitosan microspheres as a potential carrier for drugs. Int. J. Pharm. 2004; 274: 1–33
  • Shu X. Z., Zhu K. J. The release behavior of brilliant blue from calcium-alginate gel beads coated by chitosan: the preparation method effect. Eur. J. Pharm. Biopharm. 2002; 53: 193–201
  • Skjak-Braek G., Grasdalen H., Smidsrod O. Inhomogeneous polysaccharide ionic gels. Carbohydr. Polym. 1989; 10: 31–54
  • Takahashi T., Takayama K., Machida Y., Nagai T. Characterisics of polyion complexes of chitosan with sodium alginate and sodium polyacrylate. Int. J. Pharm. 1990; 61: 35–41
  • Takka S., Acarturk F. Calcium alginate microparticles for oral aministration: I Effect of sodium alginate type on drug release and drug entrapment efficiency. J. Microencapsul. 1999; 16: 275–290
  • Tonessen H. H., Karlsen J. Alginate in drug delivery systems. Drug Dev. Ind. Pharm. 2002; 28: 621–630

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.