Advanced search
Publication Cover
Drug Delivery Volume 14, 2007 - Issue 8
Submit an article Journal homepage
890
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Novel Approach for Delivery of Insulin Loaded Poly(lactide-co-glycolide) Nanoparticles Using a Combination of Stabilizers

Podaralla Satheesh Kumar Department of Pharmacy, S.G.S. Institute of Technology and Sciences, Indore, India
,
Tulsi Ram Saini Department of Pharmacy, S.G.S. Institute of Technology and Sciences, Indore, India
,
Durairaj Chandrasekar Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad, India
,
Venkata Kashyap Yellepeddi Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad, India
,
Sistla Ramakrishna Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad, India
&
Prakash V. Diwan Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad, India
Pages 517-523 | Received 16 Jan 2007, Accepted 13 Mar 2007, Published online: 10 Oct 2008

REFERENCES

  • Blanco D., Alonso M. J. Protein encapsulation and release from poly (lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the coencapsulation of surfactants. Eur. J. Pharm. Biopharm. 1998; 45: 285–294
  • Crotts G., Park T. G. Protein delivery from poly (lactic-co-glycolic acid) biodegradable microspheres: release kinetics and stability studies. J. Microencapsul. 1998; 15: 699–713
  • Gribbon E. M., Hatley R. H. M., Gard T., Blair J. A., Kampinga J., Roser J. Trehalose and novel hydrophobic sugar glasses in drug stabilization and delivery. Chemical Aspects of Drug Delivery Systems, D. R. Karsa, R. A. Stephenson. RSC, London 1996; 138–145
  • Morlock M., Koll H., Winter G., Kissel T. Microencapsulation of rh-erythropoietin, using biodegradable poly(DL-lactide-co-glycolide): protein stability and the effects of stabilizing excipients. Eur. J. Pharm. Biopharm. 1997; 43: 29–36
  • Nilhant N., Schugens Ch., Grandfils Ch., Jerome R., Teyssie Ph. Polylactide microparticles prepared by double emulsion/evaporation technique. I. Effect of primary emulsion stability. Pharm. Res. 1994; 11: 1479–1484
  • Quaglia F., Rosa G. D., Granata E., Ungaro F., Fattal E., La Rotonda M. I. Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying. J. Control. Rel. 2003; 86: 267–278
  • Rosa G. D., Iommelli R., La Rotonda M. I., Miro A., Qualgia F. Influence of the co-encapsulation of different non-ionic surfactants on the properties of PLGA insulin-loaded microspheres. J. Control. Rel. 2000; 69: 283–295
  • Wang N., Wu X. S. A novel approach to stabilization of protein drugs in poly (lactic-co-glycolic acid) microspheres using agarose hydrogel. Int. J. Pharm. 1998; 166: 1–14
  • Witschi C., Doelker E. Influence of the microencapsulation method and peptide loading on poly (lactic acid) and poly (lactic-co-glycolic acid) degradation during in vitro testing. J. Control. Rel. 1998; 51: 327–341
  • Zhu G., Mallery S. R., Schwendeman S. P. Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide). Nat. Biotech. 2000; 18: 52–57

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.