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Drug Delivery Volume 23, 2016 - Issue 9
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Research Article

Experimental studies on soft contact lenses for controlled ocular delivery of pirfinedone: in vitro and in vivo

Mei YangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and
,
Yangfan YangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and
,
Ming LeiSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China
,
Chengtian YeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and
,
Chunshun ZhaoSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China
,
Jiangang XuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and
,
Kaili WuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and
&
Minbin YuState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China, and Correspondence[email protected]
 show all
Pages 3538-3543 | Received 10 May 2016, Accepted 18 Jun 2016, Published online: 17 Jul 2016

Reference

  • Ali J, Fazil M, Qumbar M, et al. (2014). Colloidal drug delivery system: amplify the ocular delivery. Drug Deliv 23:710–25
  • Azuma A, Nukiwa T, Tsuboi E, et al. (2005). Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 171:1040–7
  • Boone A, Hui A, Jones L. (2009). Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses. Eye Contact Lens 35:260–7
  • Chowdhury S, Guha R, Trivedi R, et al. (2013). Pirfenidone nanoparticles improve corneal wound healing and prevent scarring following alkali burn. PLoS One 8:e70528
  • di Sario A, Bendia E, Svegliati Baroni G, et al. (2002). Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production. J Hepatol 37:584–91
  • Gasset AR, Kaufman HE. (1970). Therapeutic uses of hydrophilic contact lenses. Am J Ophthalmol 69:252–9
  • Gonzalez-Chomon C, Concheiro A, Alvarez-Lorenzo C. (2013). Soft contact lenses for controlled ocular delivery: 50 years in the making. Ther Deliv 4:1141–61
  • Gulsen D, Chauhan A. (2004). Ophthalmic drug delivery through contact lenses. Invest Ophthalmol Vis Sci 45:2342
  • Gulsen D, Chauhan A. (2005). Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle. Int J Pharm 292:95–117
  • Guzman-Aranguez A, Colligris B, Pintor J. (2013). Contact lenses: promising devices for ocular drug delivery. J Ocul Pharmacol Ther 29:189–99
  • Hewitson TD, Kelynack KJ, Tait MG, et al. (2001). Pirfenidone reduces in vitro rat renal fibroblast activation and mitogenesis. J Nephrol 14:453–60
  • Hui A, Boone A, Jones L. (2008). Uptake and release of ciprofloxacin-HCl from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 34:266–71
  • Karlgard CC, Wong NS, Jones LW, Moresoli C. (2003). In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials. Int J Pharm 257:141–51
  • Kompella UB, Kadam RS, Lee VH. (2010). Recent advances in ophthalmic drug delivery. Ther Deliv 1:435–56
  • Lang JC, Srajer G, Detlefs C, et al. (1995). Confirmation of quadrupolar transitions in circular magnetic X-ray dichroism at the dysprosium LIII edge. Phys Rev Lett 74:4935–8
  • Mahomed A, Tighe BJ. (2014). The design of contact lens based ocular drug delivery systems for single-day use: part (I) Structural factors, surrogate ophthalmic dyes and passive diffusion studies. J Biomater Appl 29:341–53
  • Matoba AY, Mcculley JP. (1985). The effect of therapeutic soft contact lenses on antibiotic delivery to the cornea. Ophthalmology 92:97–9
  • Phan CM, Subbaraman LN, Jones L. (2013). In vitro uptake and release of natamycin from conventional and silicone hydrogel contact lens materials. Eye Contact Lens 39:162–8
  • Pitt WG, Jack DR, Zhao Y, et al. (2011). Loading and release of a phospholipid from contact lenses. Optom Vis Sci 88:502–6
  • Raghu G, Johnson WC, Lockhart D, Mageto Y. (1999). Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label phase II study. Am J Respir Crit Care Med 159:1061–9
  • Soluri A, Hui A, Jones L. (2012). Delivery of ketotifen fumarate by commercial contact lens materials. Optom Vis Sci 89:1140–9
  • Sun G, Lin X, Zhong H, et al. (2011). Pharmacokinetics of pirfenidone after topical administration in rabbit eye. Mol Vis 17:2191–6
  • Tieppo A, Boggs AC, Pourjavad P, Byrne ME. (2014). Analysis of release kinetics of ocular therapeutics from drug releasing contact lenses: best methods and practices to advance the field. Cont Lens Anterior Eye 37:305–13
  • Tieppo A, White CJ, Paine AC, et al. (2012). Sustained in vivo release from imprinted therapeutic contact lenses. J Control Release 157:391–7
  • Wajs G, Meslard JC. (1986). Release of therapeutic agents from contact lenses. Crit Rev Ther Drug Carrier Syst 2:275–89
  • White CJ, Byrne ME. (2010). Molecularly imprinted therapeutic contact lenses. Expert Opin Drug Deliv 7:765–80
  • Wilhelmus KR. (2001). The Draize eye test. Surv Ophthalmol 45:493–515
  • Xu J, Li X, Sun F. (2011). In vitro and in vivo evaluation of ketotifen fumarate-loaded silicone hydrogel contact lenses for ocular drug delivery. Drug Deliv 18:150–8
  • Zhong H, Sun G, Lin X, et al. (2011). Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. Invest Ophthalmol Vis Sci 52:3136–42

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