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Research Article

In vitro–ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems

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Pages 582-590 | Received 05 Aug 2016, Accepted 25 Sep 2016, Published online: 21 Feb 2017

References

  • Andrade‐Vivero P, Fernandez‐Gabriel E, Alvarez-Lorenzo C, Congheiro A. (2007). Improving the loading and release of NSAIDs from pHEMA hydrogels by copolymerization with functionalized monomers. J Pharm Sci 96:802
  • Ball C, Chou SF, Jiang Y, Woodrow KA. (2016). Coaxially electrospun fiber-based microbicides facilitate broadly tunable release of maraviroc. Mater Sci Eng C 63:117–24
  • Ball C, Woodrow KA. (2014). Electrospun solid dispersions of maraviroc for rapid intravaginal preexposure prophylaxis of HIV. Antimicrob Agents Chemother 58:4855–65
  • Blakney AK, Krogstad EA, Jiang YH, Woodrow KA. (2014). Delivery of multipurpose prevention drug combinations from electrospun nanofibers using composite microarchitectures. Int J Nanomedicine 9:2967–78
  • Carson D, Jiang Y, Woodrow KA. (2015). Tunable release of multiclass anti-HIV drugs that are water-soluble and loaded at high drug content in polyester blended electrospun fibers. Pharm Res 33:125–36
  • Chen BA, Panther L, Marzinke MA, et al. (2015). Phase 1 safety, pharmacokinetics, and pharmacodynamics of dapivirine and maraviroc vaginal rings: a double-blind randomized trial. J Acquir Immune Defic Syndr 70:242–9
  • Chen DW, Liao JYY, Liu SJJ, Chan ECC. (2012). Novel biodegradable sandwich-structured nanofibrous drug-eluting membranes for repair of infected wounds: an in vitro and in vivo study. Int J Nanomedicine 7:763–71
  • Devlin B, Nuttall J, Wilder S, et al. (2013). Development of dapivirine vaginal ring for HIV prevention. Antiviral Res 100:S3–8
  • Fletcher PS, Wallace GS, Mesquita PMM, Shattock RJ. (2006). Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants. Retrovirology 3:46
  • Fu Y, Xu K, Zheng X, et al. (2012). 3D cell entrapment in crosslinked thiolated gelatin-poly (ethylene glycol) diacrylate hydrogels. Biomaterials 33:48–58
  • Holpuch AS, Hummel GJ, Tong M, et al. (2010). Nanoparticles for local drug delivery to the oral mucosa: proof of principle studies. Pharm Res 27:1224–36
  • Hsiue GH, Guu JA, Cheng CC. (2001). Poly(2-hydroxyethyl methacrylate) film as a drug delivery system for pilocarpine. Biomaterials 22:1763–9
  • Hwang CM, Sant S, Masaeli M, Kachouie NN. (2010). Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering. Biofabrication 2:1–12
  • Liu P, Wulf DO, Laru J, et al. (2013). Dissolution studies of poorly soluble drug nanosuspensions in non-sink conditions. AAPS PharmSciTech 14:748–56
  • Mabilleau G, Stancu IC, Honore T, et al. (2006). Effects of the length of crosslink chain on poly (2‐hydroxyethyl methacrylate)(pHEMA) swelling and biomechanical properties. J Biomed Mater Res A 77:35–42
  • Namur J, Citron SJ, Sellers MT, et al. (2011). Embolization of hepatocellular carcinoma with drug-eluting beads: doxorubicin tissue concentration and distribution in patient liver explants. J Hepatol 55:1332–8
  • Okuda T, Tominaga K, Kidoaki S. (2010). Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes. J Control Release 143:258–64
  • Rohan LC, Moncla BJ, Ayudhya R, et al. (2010). In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. PLoS One 5:e9310
  • Romano J, Variano B, Coplan P, et al. (2009). Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring. AIDS Res Hum Retroviruses 25:483–8
  • Sun DD, Ju TR, Lee PI. (2012). Enhanced kinetic solubility profiles of indomethacin amorphous solid dispersions in poly (2-hydroxyethyl methacrylate) hydrogels. Eur J Pharm Biopharm 81:149–58
  • Sun DD, Lee PI. (2015a). Evolution of supersaturation of amorphous pharmaceuticals: nonlinear rate of supersaturation generation regulated by matrix diffusion. Mol Pharm 12:1203–15
  • Sun DD, Lee PI. (2015b). Probing the mechanisms of drug release from amorphous solid dispersions in medium-soluble and medium-insoluble carriers. J Control Release 211:85–93
  • Wong HL, Bendayan R, Rauth AM, Wu XY. (2006). Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer. J Control Release 116: 275–84
  • Yuan Z, Zhao X, Zhao J, et al. (2015). Synergistic mediation of tumor signaling pathways in hepatocellular carcinoma therapy via dual-drug-loaded pH-responsive electrospun fibrous scaffolds. J Mater Chem B 3:3436–46