Controllable continuous sub-tenon drug delivery of dexamethasone disodium phosphate to ocular posterior segment in rabbit

References

• Abdul NN, Agarwal P, Agarwal R, et al. (2016). Intraocular distribution of topically applied hydrophilic and lipophilic substances in rat eyes. Drug Deliv 23:2765–71
   PubMed Web of Science ®Google Scholar
• Ambati J, Canakis CS, Miller JW, et al. (2000). Diffusion of high molecular weight compounds through sclera. Invest Ophthalmol Vis Sci 41:1181–5
   PubMed Web of Science ®Google Scholar
• Ambati J, Gragoudas ES, Miller JW, et al. (2000). Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci 41:1186–91
   PubMed Web of Science ®Google Scholar
• Andonova VY. (2016). A new direction in ophthalmic development: nanoparticle drug delivery systems. Curr Pharm Des. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Bansal P, Garg S, Sharma Y, Venkatesh P. (2016). Posterior segment drug delivery devices: current and novel therapies in development. J Ocul Pharmacol Ther 32:135–44
   PubMed Web of Science ®Google Scholar
• Borooah S, Jeganathan VS, Ambrecht AM, et al. (2015). Long-term visual outcomes of intravitreal ranibizumab treatment for wet age-related macular degeneration and effect on blindness rates in south-east Scotland. Eye (Lond) 29:1156–61
   PubMed Web of Science ®Google Scholar
• Bourges JL, Gautier SE, Delie F, et al. (2003). Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Invest Ophthalmol Vis Sci 44:3562–9
   PubMed Web of Science ®Google Scholar
• Calvo P, Ferreras A, Al AF, et al. (2015). Dexamethasone intravitreal implant as adjunct therapy for patients with wet age-related macular degeneration with incomplete response to ranibizumab. Br J Ophthalmol 99:723–6
   PubMed Web of Science ®Google Scholar
• Chen Q, Zheng Y, Li Y, et al. (2012). The effect of deacetylated gellan gum on aesculin distribution in the posterior segment of the eye after topical administration. Drug Deliv 19:194–201
   PubMed Web of Science ®Google Scholar
• Chennamaneni SR, Mamalis C, Archer B, et al. (2013). Development of a novel bioerodible dexamethasone implant for uveitis and postoperative cataract inflammation. J Control Release 167:53–9
   PubMed Web of Science ®Google Scholar
• Edelhauser HF, Rowe-Rendleman CL, Robinson MR, et al. (2010). Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Invest Ophthalmol Vis Sci 51:5403–20
   PubMed Web of Science ®Google Scholar
• Eljarrat-Binstock E, Domb AJ. (2006). Iontophoresis: a non-invasive ocular drug delivery. J Control Release 110:479–89
   PubMed Web of Science ®Google Scholar
• Eljarrat-Binstock E, Orucov F, Aldouby Y, et al. (2008). Charged nanoparticles delivery to the eye using hydrogel iontophoresis. J Control Release 126:156–61
   PubMed Web of Science ®Google Scholar
• Eljarrat-Binstock E, Raiskup F, Frucht-Pery J, Domb AJ. (2005). Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel. J Control Release 106:386–90
   PubMed Web of Science ®Google Scholar
• Ghate D, Brooks W, McCarey BE, Edelhauser HF. (2007). Pharmacokinetics of intraocular drug delivery by periocular injections using ocular fluorophotometry. Invest Ophthalmol Vis Sci 48:2230–7
   PubMed Web of Science ®Google Scholar
• Hamdan J, Boulze M, Aziz A, et al. (2015). Corneal neovascularisation treatments compared: subconjunctival bevacizumab injections and/or photodynamic therapy. J Fr Ophtalmol 38:924–33
   PubMed Web of Science ®Google Scholar
• Hennessy AL, Katz J, Covert D, et al. (2010). Videotaped evaluation of eyedrop instillation in glaucoma patients with visual impairment or moderate to severe visual field loss. Ophthalmology 117:2345–52
   PubMed Web of Science ®Google Scholar
• Hettinga YM, Verhagen FH, van Genderen M, de Boer JH. (2014). Characteristics of childhood uveitis leading to visual impairment and blindness in the Netherlands. Acta Ophthalmol 92:798–804
   PubMed Web of Science ®Google Scholar
• Hosseini K, Matsushima D, Johnson J, et al. (2008). Pharmacokinetic study of dexamethasone disodium phosphate using intravitreal, subconjunctival, and intravenous delivery routes in rabbits. J Ocul Pharmacol Ther 24:301–8
   PubMed Web of Science ®Google Scholar
• Hsu J. (2007). Drug delivery methods for posterior segment disease. Curr Opin Ophthalmol 18:235–9
   PubMed Web of Science ®Google Scholar
• Huang Z, Yang W, Zong Y, et al. (2016). A study of the dexamethasone sodium phosphate release properties from a periocular capsular drug delivery system. Drug Deliv 23:849–57
   PubMed Web of Science ®Google Scholar
• Janoria KG, Gunda S, Boddu SH, Mitra AK. (2007). Novel approaches to retinal drug delivery. Expert Opin Drug Deliv 4:371–88
   PubMed Web of Science ®Google Scholar
• Jiang J, Moore JS, Edelhauser HF, Prausnitz MR. (2009). Intrascleral drug delivery to the eye using hollow microneedles. Pharm Res 26:395–403
   PubMed Web of Science ®Google Scholar
• Kang-Mieler JJ, Osswald CR, Mieler WF. (2014). Advances in ocular drug delivery: emphasis on the posterior segment. Expert Opin Drug Deliv 11:1647–60
   PubMed Web of Science ®Google Scholar
• Lajunen T, Nurmi R, Kontturi L, et al. (2016). Light activated liposomes: functionality and prospects in ocular drug delivery. J Control Release. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Liu S, Dozois MD, Chang CN, et al. (2016). Prolonged ocular retention of mucoadhesive nanoparticle eye drop formulation enables treatment of eye diseases using significantly reduced dosage. Mol Pharm 13:2897–905
   PubMed Web of Science ®Google Scholar
• Liu X, Wang M, Zhao C, et al. (2015). The efficacy and safety of subconjunctival triamcinolone acetonide injections in treatment of uveitic macular edema. Zhonghua Yan Ke Za Zhi 51:734–8
   PubMedGoogle Scholar
• Lowder C, Belfort RJ, Lightman S, et al. (2011). Dexamethasone intravitreal implant for noninfectious intermediate or posterior uveitis. Arch Ophthalmol 129:545–53
   PubMed Web of Science ®Google Scholar
• Meng Y, Sun S, Li J, et al. (2014). Sustained release of triamcinolone acetonide from an episcleral plaque of multilayered poly-ɛ-caprolactone matrix. Acta Biomater 10:126–33
   PubMed Web of Science ®Google Scholar
• Miserocchi E, Berchicci L, Iuliano L, et al. (2016). Dexamethasone intravitreal implant in serpiginous choroiditis. Br J Ophthalmol. [Epub ahead of print]
   Web of Science ®Google Scholar
• Nagai N, Kaji H, Onami H, et al. (2014). A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye. Acta Biomater 10:680–7
   PubMed Web of Science ®Google Scholar
• Patane MA, Schubert W, Sanford T, et al. (2013). Evaluation of ocular and general safety following repeated dosing of dexamethasone phosphate delivered by transscleral iontophoresis in rabbits. J Ocul Pharmacol Ther 29:760–9
   PubMed Web of Science ®Google Scholar
• Peptu CA, Popa M, Savin C, et al. (2015). Modern drug delivery systems for targeting the posterior segment of the eye. Curr Pharm Des 21:6055–69. 2015-01-20
   PubMed Web of Science ®Google Scholar
• Pescina S, Govoni P, Antopolsky M, et al. (2015). Permeation of proteins, oligonucleotide and dextrans across ocular tissues: experimental studies and a literature update. J Pharm Sci 104:2190–202
   PubMed Web of Science ®Google Scholar
• Quek DT, Ong GT, Perera SA, et al. (2011). Persistence of patients receiving topical glaucoma monotherapy in an Asian population. Arch Ophthalmol 129:643–8
   PubMed Web of Science ®Google Scholar
• Smith SJ, Smith BD, Mohney BG. (2014). Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review. Br J Ophthalmol 98:292–7
   PubMed Web of Science ®Google Scholar
• Suen WL, Wong HS, Yu Y, et al. (2013). Ultrasound-mediated transscleral delivery of macromolecules to the posterior segment of rabbit eye in vivo. Invest Ophthalmol Vis Sci 54:4358–65
   PubMed Web of Science ®Google Scholar
• Thakur A, Kadam RS, Kompella UB. (2011). Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug Metab Dispos 39:771–81
   PubMed Web of Science ®Google Scholar
• Thakur SR, Tekko I, McAvoy K, et al. (2016). Minimally invasive microneedles for ocular drug delivery. Expert Opin Drug Deliv. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Thrimawithana TR, Young S, Bunt CR, et al. (2011). Drug delivery to the posterior segment of the eye. Drug Discov Today 16:270–7
   PubMed Web of Science ®Google Scholar
• Tsang AC, Virgili G, Abtahi M, Gottlieb CC. (2016). Intravitreal dexamethasone implant for the treatment of macular edema in chronic non-infectious uveitis. Ocul Immunol Inflamm. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Weijtens O, van der Sluijs FA, Schoemaker RC, et al. (1997). Peribulbar corticosteroid injection: vitreal and serum concentrations after dexamethasone disodium phosphate injection. Am J Ophthalmol 123:358–63
   PubMed Web of Science ®Google Scholar
• Zatic T, Bendelic E, Paduca A, et al. (2015). Rapid assessment of avoidable blindness and diabetic retinopathy in Republic of Moldova. Br J Ophthalmol 99:832–6
   PubMed Web of Science ®Google Scholar