Fabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma

References

• Ali MS, Alam MS, Anwer T, et al. (2012). Formulation, characterization and in-vivo study of nanoemulsion topical gel of beclomethasone dipropionate for psoriasis. World J Pharm Pharm Sci 1:839–57.
   Google Scholar
• Block MJ. (2000). Chemcycolpedia. Washington (DC): American Chemical Society, 106–7.
   Google Scholar
• Bouchemal K, Briançon S, Perrier E, et al. (2004). Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimization. Int J Pharm 280:241–51.
   PubMed Web of Science ®Google Scholar
• Burapapadh K, Chantasart D, Sriamornsaka P. (2010). Fabrication of pectin-based nanoemulsion loaded with itraconazole for pharmaceutical application. Carbohydr Polym 82:384–93.
   Web of Science ®Google Scholar
• Czyz J, Madeja Z, Irmer U, et al. (2005). Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro. Int J Cancer 114:12–18.
   PubMed Web of Science ®Google Scholar
• Deveswaran R, Abraham S, Bharath S, et al. (2009). Design and characterization of diclofenac sodium tablets containing tamarind seed polysaccharide as release retardant. Int J PharmTech Res 1:191–5.
   Google Scholar
• Estanqueiro M, Amaral MH, Conceicao J, Sousa Lobo JM. (2015). Nanotechnological carriers for cancer chemotherapy: the state of the art. Colloids Surf B Biointerfaces 126:631–48.
   PubMed Web of Science ®Google Scholar
• Forgiarini A, Esquena J, González C, et al. (2001). Formation of nano-emulsions by low-energy emulsification methods at constant temperature. Langmuir 17:2076–83.
   Web of Science ®Google Scholar
• Fonseca JV, Bentley LB, Iyomasa MM, et al. (2010). Evaluation of protective effect of a water-in-oil microemulsion incorporating quercetin against UVB-induced damage in hairless mice skin. J Pharm Pharmaceut Sci 13:274–85. (www.cspsCanada.org)
   PubMed Web of Science ®Google Scholar
• Funami T, Zhang G, Hiroe M, et al. (2007). Effects of proteinaceous moiety on the emulsifying properties of sugar beet pectin. Food Hydrocolloid 21:319–1329.
   Web of Science ®Google Scholar
• Garg T, Goyal AK, Marwah A, Rath G, (2015). Permeation enhancer strategies in transdermal drug delivery. Drug Deliv 23:564-78.Garg T, Goyal AK, Marwah A, Rath G, (2015). Permeation enhancer strategies in transdermal drug delivery. Drug Deliv 23:564-78.
   Google Scholar
• Gupta A, Kaur CD, Saraf S, Saraf S. (2016). Formulation, characterization and evaluation of ligand-conjugated biodegradable quercetin nanoparticle for active targeting. Artif Cells Nanomed Biotechnol 44:960–70.
   PubMed Web of Science ®Google Scholar
• Gupta S, Afaq F, Mukhtar H, et al. (2001). Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells. Biochem Biophys Res Commun 287:914–20.
   PubMed Web of Science ®Google Scholar
• Huang Q, Yu H. (2012). Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions. J Agric Food Chem 60:5373–9.
   PubMed Web of Science ®Google Scholar
• Jana S, Lakshman D, Sen KK. (2010). Development and evaluation of epichlorohydrin cross-linked mucoadhesive patches of tamarind seed polysaccharide for buccal application. IJPSDR 2:193–8.
   Google Scholar
• Kanokporn B, Mont KV, Doungdaw C, et al. (2010). Fabrication of pectin-based nanoemulsions loaded with itraconazole for pharmaceutical application. Carbohydr Polym 8:384–93.
   Google Scholar
• Khan MA, Pandit J, Sultana Y, et al. (2015). Novel carbopol-based transfersomal gel of 5-fluorouracil for skin cancer treatment: in vitro characterization and in vivo study. Drug Deliv 22:795–802.
   PubMed Web of Science ®Google Scholar
• Kirjavainen M, Urtti A, Valjakka-Koskela R, et al. (1999). Liposome-skin interactions and their effects on the skin permeation of drugs. Eur J Pharm Sci 7:279–86.
   PubMed Web of Science ®Google Scholar
• Kokate CK. (1991). Practical pharmacognosy. 3rd ed. New Delhi: Vallabh Prakashan.
   Google Scholar
• Kulkarni GT. (2011). Herbal drug delivery systems: an emerging area in herbal drug research. J Chronother Drug Deliv 2:113–19.
   Google Scholar
• Kulkarni D, Ddwivedi DK, Sarin JPS, et al. (1997). Tamarind seed polyose: a potential polysaccharide for sustained release of verapamil hydrochloride as a model drug. Indian J Pharm Sci 59:1–7.
   Google Scholar
• Lepley DM, Pelling JC. (1997). Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin. Mol Carcinog 19:74–82.
   PubMed Web of Science ®Google Scholar
• Livingston Raja NR, Jegan N, Wesley J. (2008). Antiulcerogenic activity of alcoholic extract of the leaves of tamarindus indica(L) on experimental ulcer models. Pharmacologyonline 3:85–92.
   Google Scholar
• Malviya R, Srivastava P, Bansal M, et al. (2010). Formulation and optimization of sustained release matrix tablets of diclofenac sodium using pectin as release modifier. Int J Drug Dev Res 2:330–5.
   Google Scholar
• Malviya R, Shukla P, Srivastava P. (2009). Preparation, characterization and evaluation of chitosan gum arabic coacervates as excipient in fast dissolving/disintegrating dosage form. FA-BAD J Pharmaceut Sci 34:213–23.
   Google Scholar
• Mangalathillam S, Reginold S, Nair A, et al. (2012). Curcumin loaded chitin nanogels for Skin cancer treatment via the transdermal Route. Nanoscale 4:239–50.
   PubMed Web of Science ®Google Scholar
• Mangalathillam S, Reginold S, Nair A, et al. (2013). Development and evaluation of 5-fluorouracil loaded chitin nanogels for treatment of skin cancer. Carbohydr Polym 91:48–57.
   PubMed Web of Science ®Google Scholar
• Mohamed HA, Mohamed BE, Ahmed KE. (2015). Physicochemical properties of tamarind seed polysaccharides. J Food Process Technol 6:1–5.
   Google Scholar
• Mukerje A, Vishwanatha JK. (2009). Characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy. Anticancer Res 29:3867–76.
   PubMed Web of Science ®Google Scholar
• Mukhtar H, Afaq F, Vaqar M. (2005). Photochemoprevention of ultraviolet B signaling and photocarcinogenesis. Mutat Res 571:153–73.
   PubMed Web of Science ®Google Scholar
• Modi J, Patel JK. (2011). Nanoemulsion-based gel formulation of aceclofenac for topical delivery. Int J Pharm Pharm Sci Res 1:6–12.
   Google Scholar
• Patel D, Shukla S, Gupta S. (2007). Apigenin and cancer chemoprevention: progress, potential and promise (review). Int J Oncol 30:233–45.
   PubMed Web of Science ®Google Scholar
• Pathan IB, Mallikarjuna Setty C. (2011). Enhancement of transdermal delivery of tamoxifen citrate using nanoemulsion vehicle. Int J PharmTech Res 3:287–97.
   Google Scholar
• Sarwa KK, Rudrapal M, Mazumder B. (2013). Topical ethosomal capsaicin attenuates edema and nociception in arthritic rats. Drug Deliv Early Online: 1–10. DOI: 10.3109/10717544.2013.861041.
   Web of Science ®Google Scholar
• Sano M, Miyata E, Tamano S, et al. (1996). Lack of carcinogenicity of tamarind seed polysaccharide in B6C3F1 mice. Food Chem Toxicol 34:463–7.
   PubMed Web of Science ®Google Scholar
• Swarnlata S, Gupta A, Alexander A, et al. (2015). Advancements and avenues in nanophytomedicines for better pharmacological responses. J Nanosci Nanotechnol 15:1–10.
   PubMed Web of Science ®Google Scholar
• Siepmann J, Peppas NA. (2001). Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)). Adv Drug Deliv Rev 48:139–57.
   PubMed Web of Science ®Google Scholar
• Songyot A, Yoshinobu F, Siriporn O, Hideki I. (2012). Preparation of lipid nanoemulsions incorporating curcumin for cancer therapy. J Nanotechnol 2012:1–11.
   Google Scholar
• Thadros T, Izquierdo P, Esquena J, et al. (2004). Formation and stability of nano-emulsions. Adv Colloid Interface Sci 108–109:303–18.
   PubMed Web of Science ®Google Scholar
• Wang W, Heideman L, Chung CS, et al. (2000). Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol Carcinog 28:102–10.
   PubMed Web of Science ®Google Scholar
• Yee SB, Lee JH, Chung HY, et al. (2003). Inhibitory effects of luteolin isolated from Ixerissonchifolia Hance on the proliferation of HepG2 humanhepatocellular carcinoma cells. Arch Pharm Res 26:151–6.
   PubMed Web of Science ®Google Scholar
• Yin F, Giuliano AE, Law RE, et al. (2001). Apigenin inhibits growth and induces G2/Marrest by modulating cyclin-CDK regulators and ERK MAP kinase activation in breast carcinoma cells. Anticancer Res 21:413–20.
   PubMed Web of Science ®Google Scholar
• Yin F, Giuliano AE, Van Herle AJ. (1999). Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO). Anticancer Res 19:4297–303.
   PubMed Web of Science ®Google Scholar
• Zhai Y, Guo S, Yang C, et al. (2013). Preparation and in vitro evaluation of apigenin-loaded polymeric micelles. Colloids Surf A Physicochem Eng Asp 429:24–30.
   Web of Science ®Google Scholar
• Zhang JD, Liu D, Huang Y, et al. (2012). Biopharmaceutics classification and intestinal absorption study of apigenin. Int J Pharm 436:311–17.
   PubMed Web of Science ®Google Scholar
• Zhang LW, Al-Suwayeh SA, Hung CF, et al. (2011). Oil components modulate the skin delivery of 5-aminolevulinic acid and its ester produg from oil-in –water and water-in-oil nanoemulsions. Int J Nanomed 6:693–704.
   PubMed Web of Science ®Google Scholar