1,722
Views
26
CrossRef citations to date
0
Altmetric
Research Article

Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice

, , , , , , , , , , , & show all
Pages 1350-1359 | Received 03 Aug 2017, Accepted 05 Sep 2017, Published online: 15 Sep 2017

References

  • Acharya S, Sahoo SK. (2011). PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect. Adv Drug Deliv Rev 63:170–83.
  • Akar Y, Yucel G, Durukan A, et al. (2005). Systemic toxicity of tacrolimus given by various routes and the response to dose reduction. Clin Exp Ophthalmol 33:53–9.
  • Ali Y, Diez J, Selander L, et al. (2016). The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice. Diabetologia 59:1007–11.
  • Amatya S, Park EJ, Park JH, et al. (2013). Drug release testing methods of polymeric particulate drug formulations. J Pharm Investig 43:259–66.
  • Anon (1995). Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. European Mycophenolate Mofetil Cooperative Study Group. Lancet 345:1321–5.
  • Barker CF, Billingham RE. (1968). The role of afferent lymphatics in the rejection of skin homografts. J Exp Med 128:197–221.
  • Bluestone JA, Herold K, Eisenbarth G. (2010). Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 464:1293–300.
  • Cardona K, Korbutt GS, Milas Z, et al. (2006). Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nat Med 12:304–6.
  • Carlsson PO, Palm F, Andersson A, Liss P. (2001). Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50:489–95.
  • Crawley JB, Rawlinson L, Lali FV, et al. (1997). T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation. J Biol Chem 272:15023–7.
  • Dash S, Murthy PN, Nath L, Chowdhury P. (2010). Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm 67:217–23.
  • Delaune V, Berney T, Lacotte S, Toso C. (2017). Intraportal islet transplantation: the impact of the liver microenvironment. Transpl Int 30:227–38.
  • Elliott RB, Escobar L, Tan PL, et al. (2007). Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xenotransplantation 14:157–61.
  • Gupta B, Poudel BK, Pathak S, et al. (2016). Effects of formulation variables on the particle size and drug encapsulation of imatinib-loaded solid lipid nanoparticles. AAPS PharmSciTech 17:652–62.
  • Hamawy MM, Knechtle SJ. (2003). An overview of the actions of cyclosporine and FK506. Transplant Rev 17:165–71.
  • Haque MR, Lee DY, Ahn CH, et al. (2014). Local co-delivery of pancreatic islets and liposomal clodronate using injectable hydrogel to prevent acute immune reactions in a type 1 diabetes. Pharm Res 31:2453–62.
  • Harlan DM, Kenyon NS, Korsgren O, Roep BO. (2009). Current advances and travails in islet transplantation. Diabetes 58:2175–84.
  • Homey B, Assmann T, Vohr HW, et al. (1998). Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses. J Immunol 160:5331–40.
  • Hwang PTJ, Shah DK, Garcia JA, et al. (2017). Encapsulation of human islets using a biomimetic self-assembled nanomatrix gel for protection against cellular inflammatory responses. ACS Biomater Sci Eng. DOI: 10.1021/acsbiomaterials.7b00261.
  • Jeong JH, Yook S, Lee H, et al. (2013). Effects of surface camouflaged islet transplantation on pathophysiological progression in a db/db type 2 diabetic mouse model. Biochem Biophys Res Commun 433:513–18.
  • Jiang K, Weaver JD, Li Y, et al. (2017). Local release of dexamethasone from macroporous scaffolds accelerates islet transplant engraftment by promotion of anti-inflammatory M2 macrophages. Biomaterials 114:71–81.
  • Karanam BV, Miller RR, Colletti A, et al. (1998). Disposition of L-732,531, a potent immunosuppressant, in rats and baboons. Drug Metab Dispos 26:949–57.
  • Kim HJ, Yoon IH, Min BH, et al. (2016). Porcine antigen-specific IFN-gamma ELISpot as a potentially valuable tool for monitoring cellular immune responses in pig-to-non-human primate islet xenotransplantation. Xenotransplantation 23:310–19.
  • Kondo S, Asano Y, Koizumi N, et al. (2015). Novel pH-responsive polymeric micelles prepared through self-assembly of amphiphilic block copolymer with poly-4-vinylpyridine block synthesized by mechanochemical solid-state polymerization. Chem Pharm Bull 63:489–94.
  • Kourtzelis I, Magnusson PU, Kotlabova K, et al. (2015). Regulation of instant blood mediated inflammatory reaction (IBMIR) in pancreatic islet xeno-transplantation: points for therapeutic interventions. Adv Exp Med Biol 865:171–88.
  • Lakkis FG, Arakelov A, Konieczny BT, Inoue Y. (2000). Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat Med 6:686–8.
  • Li CJ, Li L. (2015). Tacrolimus in preventing transplant rejection in Chinese patients – optimizing use. Drug Des Devel Ther 9:473–85.
  • Makadia HK, Siegel SJ. (2011). Poly lactic-co-glycolic acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers 3:1377–97.
  • Miyamoto Y, Uno T, Yamamoto H, et al. (2004). Pharmacokinetic and immunosuppressive effects of tacrolimus-loaded biodegradable microspheres. Liver Transpl 10:392–6.
  • Naziruddin B, Iwahashi S, Kanak MA, et al. (2014). Evidence for instant blood-mediated inflammatory reaction in clinical autologous islet transplantation. Am J Transplant 14:428–37.
  • Pathak S, Gupta B, Poudel BK, et al. (2016a). Preparation of high-payload, prolonged-release biodegradable poly(lactic-co-glycolic acid)-based tacrolimus microspheres using the single-jet electrospray method. Chem Pharm Bull 64:171–8.
  • Pathak S, Regmi S, Gupta B, et al. (2016b). Hybrid congregation of islet single cells and curcumin-loaded polymeric microspheres as an interventional strategy to overcome apoptosis associated with pancreatic islets transplantation. ACS Appl Mater Interfaces 8:25702–13.
  • Piekoszewski W, Chow FS, Jusko WJ. (1993). Disposition of tacrolimus (FK 506) in rabbits. Role of red blood cell binding in hepatic clearance. Drug Metab Dispos 21:690–8.
  • Przepiorka D, Nash RA, Wingard JR, et al. (1999). Relationship of tacrolimus whole blood levels to efficacy and safety outcomes after unrelated donor marrow transplantation. Biol Blood Marrow Transplant 5:94–7.
  • Rajab A. (2010). Islet transplantation: alternative sites. Curr Diab Rep 10:332–7.
  • Regmi S, Cao J, Pathak S, et al. (2017). A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation. Int J Pharm 520:163–72.
  • Salama BF, Korbutt GS. (2017). Porcine islet xenografts: a clinical source of ss-cell grafts. Curr Diab Rep 17:14.
  • Sarisozen C, Pan J, Dutta I, Torchilin VP. (2017). Polymers in the co-delivery of siRNA and anticancer drugs to treat multidrug-resistant tumors. J Pharm Investig 47:37–49.
  • Seo JW, Kim KJ, Kim SH, et al. (2015). Effect of process parameters on formation and aggregation of nanoparticles prepared with a Shirasu porous glass membrane. Chem Pharm Bull 63:792–8.
  • Sevc J, Goldberg D, Van Gorp S, et al. (2013). Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: effect on spinally grafted human neural precursor survival. Exp Neurol 248:85–99.
  • Shapiro AM, Lakey JR, Rajotte RV, et al. (1995). Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation 59:1060–3.
  • Shapiro AM, Lakey JR, Ryan EA, et al. (2000). Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230–8.
  • Shapiro AM, Ricordi C, Hering BJ, et al. (2006). International trial of the Edmonton protocol for islet transplantation. N Engl J Med 355:1318–30.
  • Shimoda M, Matsumoto S. (2017). Microencapsulation in clinical islet xenotransplantation. Methods Mol Biol 1479:335–45.
  • Solari MG, Washington KM, Sacks JM, et al. (2009). Daily topical tacrolimus therapy prevents skin rejection in a rodent hind limb allograft model. Plast Reconstr Surg 123:17S–25S.
  • Stokes RA, Cheng K, Lalwani A, et al. (2017a). Transplantation sites for human and murine islets. Diabetologia 60:1961–71.
  • Stokes RA, Simond DM, Burns H, et al. (2017b). Transplantation sites for porcine islets. Diabetologia 60:1972–6.
  • Thomson AW, Bonham CA, Zeevi A. (1995). Mode of action of tacrolimus (FK506): molecular and cellular mechanisms. Ther Drug Monit 17:584–91.
  • Unadkat JV, Schnider JT, Feturi FG, et al. (2017). Single implantable FK506 disk prevents rejection in vascularized composite allotransplantation. Plast Reconstr Surg 139:403e–14.
  • Valdes-Gonzalez RA, Dorantes LM, Garibay GN, et al. (2005). Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study. Eur J Endocrinol 153:419–27.
  • Van Der Windt DJ, Bottino R, Casu A, et al. (2009). Long-term controlled normoglycemia in diabetic non-human primates after transplantation with hCD46 transgenic porcine islets. Am J Transplant 9:2716–26.
  • Venkataramanan R, Swaminathan A, Prasad T, et al. (1995). Clinical pharmacokinetics of tacrolimus. Clin Pharmacokinet 29:404–30.
  • Wingard JR, Nash RA, Przepiorka D, et al. (1998). Relationship of tacrolimus (FK506) whole blood concentrations and efficacy and safety after HLA-identical sibling bone marrow transplantation. Biol Blood Marrow Transplant 4:157–63.
  • Zahir H, Mccaughan G, Gleeson M, et al. (2004). Changes in tacrolimus distribution in blood and plasma protein binding following liver transplantation. Ther Drug Monit 26:506–15.
  • Zhao ZM, Wang Y, Han J, et al. (2015). Preparation and characterization of amphiphilic calixarene nanoparticles as delivery carriers for paclitaxel. Chem Pharm Bull 63:180–6.