Nanoemulsion-based delivery system for enhanced oral bioavailability and Caco-2 cell monolayers permeability of berberine hydrochloride

References

• Aboalnaja KO, Yaghmoor S, Kumosani TA, Mcclements DJ. (2016). Utilization of nanoemulsions to enhance bioactivity of pharmaceuticals, supplements, and nutraceuticals: nanoemulsion delivery systems and nanoemulsion excipient systems. Expert Opin Drug Deliv 13:1327–36.
   PubMed Web of Science ®Google Scholar
• Akhtar J, Siddiqui HH, Fareed S, et al. (2016). Nanoemulsion: for improved oral delivery of repaglinide. Drug Deliv 23:2026–34.
   PubMed Web of Science ®Google Scholar
• Ashiru-Oredope DA, Patel N, Forbes B, et al. (2011). The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers. Int J Pharm 409:164–8.
   PubMed Web of Science ®Google Scholar
• Balimane PV, Patel K, Marino A, Chong S. (2004). Utility of 96 well Caco-2 cell system for increased throughput of P-gp screening in drug discovery. Eur J Pharm Biopharm 58:99–105.
   PubMed Web of Science ®Google Scholar
• Bansal T, Mishra G, Jaggi M, et al. (2009). Effect of P-glycoprotein inhibitor, verapamil, on oral bioavailability and pharmacokinetics of irinotecan in rats. Eur J Pharm Sci 36:580–90.
   PubMed Web of Science ®Google Scholar
• Bhushani JA, Karthik P, Anandharamakrishnan C. (2016). Nanoemulsion based delivery system for improved bioaccessibility and Caco-2 cell monolayer permeability of green tea catechins. Food Hydrocoll 56:372–82.
   Web of Science ®Google Scholar
• Chen C, Tao C, Liu Z, et al. (2015). A randomized clinical trial of berberine hydrochloride in patients with diarrhea: predominant irritable bowel syndrome. Phytother Res 29:1822–7.
   PubMed Web of Science ®Google Scholar
• Cheng L, Xu P-H, Shen G, et al. (2015). Improve bile duct-targeted drug delivery and therapeutic efficacy for cholangiocarcinoma by cucurbitacin B loaded phospholipid complex modified with berberine hydrochloride. Int J Pharm 489:148–57.
   PubMed Web of Science ®Google Scholar
• Gutiérrez J, González C, Maestro A, et al. (2008). Nano-emulsions: new applications and optimization of their preparation. Curr Opin Colloid Interface Sci 13:245–51.
   Web of Science ®Google Scholar
• Habtemariam S. (2016). Berberine and inflammatory bowel disease: a concise review. Pharmacol Res 113:592–9.
   PubMed Web of Science ®Google Scholar
• He L, Liu G-Q. (2002). Effects of various principles from Chinese herbal medicine on rhodamine123 accumulation in brain capillary endothelial cells. Acta Pharmacol Sin 23:591–6.
   PubMed Web of Science ®Google Scholar
• Jaiswal M, Dudhe R, Sharma P. (2015). Nanoemulsion: an advanced mode of drug delivery system. 3 Biotech 5:123–7.
   PubMedGoogle Scholar
• James MA, Fu H, Liu Y, et al. (2011). Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis. Mol Carcinog 50:1–7.
   PubMed Web of Science ®Google Scholar
• Khani S, Keyhanfar F, Amani A. (2016). Design and evaluation of oral nanoemulsion drug delivery system of mebudipine. Drug Deliv 23:2035–43.
   PubMed Web of Science ®Google Scholar
• Lee C-H, Chen J-C, Hsiang C-Y, et al. (2007). Berberine suppresses inflammatory agents-induced interleukin-1β and tumor necrosis factor-α productions via the inhibition of IκB degradation in human lung cells. Pharmacol Res 56:193–201.
   PubMed Web of Science ®Google Scholar
• Liu Q-F, Shi X-J, Li Z-D, et al. (2014). Pharmacokinetic comparisons of berberine and palmatine in normal and metabolic syndrome rats. J Ethnopharmacol 151:287–91.
   PubMed Web of Science ®Google Scholar
• Lu X, Hu X, Xiang X, et al. (2011). Effect of pH on apparent oil/water partition coefficient of berberine hydrochloride. Central South Pharmacy 9:748–51.
   Google Scholar
• Mehta S, Kaur G, Mutneja R, Bhasin K. (2009). Solubilization, microstructure, and thermodynamics of fully dilutable U-type Brij microemulsion. J Colloid Interface Sci 338:542–9.
   PubMed Web of Science ®Google Scholar
• Najar I, Sachin B, Sharma S, et al. (2010). Modulation of P‐glycoprotein ATPase activity by some phytoconstituents. Phytother Res 24:454–8.
   PubMed Web of Science ®Google Scholar
• Piazzini V, Monteforte E, Luceri C, et al. (2017). Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches. Drug Deliv 24:380–90.
   PubMed Web of Science ®Google Scholar
• Qi J, Zhuang J, Wu W, et al. (2011). Enhanced effect and mechanism of water-in-oil microemulsion as an oral delivery system of hydroxysafflor yellow A. Int J Nanomed 6:985.
   PubMed Web of Science ®Google Scholar
• Qiu W, Jiang X, Liu C, et al. (2009). Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp. Phytother Res 23:1553–8.
   PubMed Web of Science ®Google Scholar
• Shen N, Li C, Huan Y, Shen Z. (2010). Advances of the mechanism study on berberine in the control of blood glucose and lipid as well as metabolism disorders. Yao Xue Xue Bao = Acta Pharmaceutica Sin 45:699–704.
   PubMedGoogle Scholar
• Sun N, Chan F-Y, Lu Y-J, et al. (2014). Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity. PLoS One 9:e97514.
   PubMed Web of Science ®Google Scholar
• Tan W, Li Y, Chen M, Wang Y. (2011). Berberine hydrochloride: anticancer activity and nanoparticulate delivery system. Int J Nanomed 6:1773.
   PubMedGoogle Scholar
• Wen S-Q, Jeyakkumar P, Avula SR, et al. (2016). Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation. Bioorganic Med Chem Lett 26:2768–73.
   PubMed Web of Science ®Google Scholar
• Xiang D, Tang T, Peng J, et al. (2010). Comparison of conductivity-water content curve and visual methods for ascertaintation of the critical water content of O/W microemulsions formation. Yao Xue Xue Bao = Acta Pharmaceutica Sinica 45:1052–6.
   PubMedGoogle Scholar
• Zhang D, Li A, Xie J, Ji C. (2010). In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria. Aquacult Res 41:1095–100.
   Web of Science ®Google Scholar
• Zhang Y, Cui Y. (2008). Influence of 2-hydroxypropyl-β-cyclodextrin complexation on P-glycoprotein drug pump in the intestine of rats. Chin Pharmacol Bull 24:1318–23.
   Google Scholar
• Zhu H-J, Liu G-Q. (2003). Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells. Acta Pharmacol Sin 24:1143–9.
   PubMed Web of Science ®Google Scholar