2,704
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Improvement of chemosensitivity and inhibition of migration via targeting tumor epithelial-to-mesenchymal transition cells by ADH-1-modified liposomes

, , , , , , , , & show all
Pages 112-121 | Received 17 Oct 2017, Accepted 11 Dec 2017, Published online: 20 Dec 2017

References

  • Acloque H, Adams MS, Fishwick K, et al. (2009). Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest 119:1438–49.
  • Allen TM. (1998). Liposomal drug formulations. Rationale for development and what we can expect for the future. Drugs 56:747–56.
  • Augustine CK, Yoshimoto Y, Gupta M, et al. (2008). Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. Cancer Res 68:3777–84.
  • Blanco E, Hsiao A, Mann AP, et al. (2011). Nanomedicine in cancer therapy: innovative trends and prospects. Cancer Sci 102:1247–52.
  • Burden-Gulley SM, Gates TJ, Craig SE, et al. (2009). Novel peptide mimetic small molecules of the HAV motif in N-cadherin inhibit N-cadherin-mediated neurite outgrowth and cell adhesion. Peptides 30:2380–7.
  • Chambers AF, Groom AC, MacDonald IC. (2002). Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2:563–72.
  • Cheng GZ, Chan J, Wang Q, et al. (2007). Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res 67:1979–87.
  • De Wever O, Westbroek W, Verloes A, Bloemen N, Bracke M, Gespach C, Bruyneel E, Mareel M. (2004). Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding. J Cell Sci 117:4691–703.
  • Geers B, De Wever O, Demeester J, et al. (2013). Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery. Small 9:4027–35.
  • Guo Z, He B, Jin H, et al. (2014). Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin alphavbeta3 clustering. Biomaterials 35:6106–17.
  • Guo Z, He B, Yuan L, et al. (2015). Dual targeting for metastatic breast cancer and tumor neovasculature by EphA2-mediated nanocarriers. Int J Pharmaceu 493:380–9.
  • Halbleib JM, Nelson WJ. (2006). Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev 20:3199–214.
  • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100:57–70.
  • Hazan RB, Phillips GR, Qiao RF, et al. (2000). Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 148:779–90.
  • Hazan RB, Qiao R, Keren R, et al. (2004). Cadherin switch in tumor progression. Ann N Y Acad Sci 1014:155–63.
  • Hugo H, Ackland ML, Blick T, et al. (2007). Epithelial–mesenchymal and mesenchymal–epithelial transitions in carcinoma progression. J Cell Physiol 213:374–83.
  • Kerbel RS. (1990). Growth dominance of the metastatic cancer cell: cellular and molecular aspects. Adv Cancer Res 55:87–132.
  • Li QQ, Wang WJ, Xu JD, et al. (2007a). Involvement of CD147 in regulation of multidrug resistance to P-gp substrate drugs and in vitro invasion in breast cancer cells. Cancer Sci 98:1064–9.
  • Li QQ, Wang WJ, Xu JD, et al. (2007b). Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells. Cancer Sci 98:1767–74.
  • Li QQ, Xu JD, Wang WJ, et al. (2009). Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res 15:2657–65.
  • Li S, Wang K, Shi Y, et al. (2016). Novel biological functions of ZIF-NP as a delivery vehicle: high pulmonary accumulation, favorable biocompatibility, and improved therapeutic outcome. Adv Funct Mater 26:2715–27.
  • Marcucci F, Lefoulon F. (2004). Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress. Drug Discov Today 9:219–28.
  • Nieto MA. (2009). Epithelial-Mesenchymal transitions in development and disease: old views and new perspectives. Int J Dev Biol 53:1541–7.
  • Qi X, Zhang L, Lu X. (2016). New Insights into the Epithelial-to-Mesenchymal transition in cancer. Trend Pharmacol Sci 37:246–8.
  • Qin C, He B, Dai W, et al. (2014). The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3. Biomaterials 35:5908–20.
  • Su ZZ, Austin VN, Zimmer SG, Fisher PB. (1993). Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells. Oncogene 8:1211–19.
  • Thiery JP, Acloque H, Huang RY, Nieto MA. (2009). Epithelial-mesenchymal transitions in development and disease. Cell 139:871–90.
  • Voulgari A, Pintzas A. (2009). Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochimica Et Biophysica Acta 1796:75–90.
  • Wang X, Ling MT, Guan XY, et al. (2004). Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells. Oncogene 23:474–82.
  • Wang XX, Li YB, Yao HJ, et al. (2011). The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells. Biomaterials 32:5673–87.
  • Wheelock MJ, Shintani Y, Maeda M, et al. (2008). Cadherin switching. J Cell Sci 121:727–35.
  • Xiang Y, Liang L, Wang X, et al. (2011). Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes. J Controlled Release 152:402–10.
  • Yang AD, Fan F, Camp ER, et al. (2006). Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res 12:4147–53.
  • Yang JM, Xu Z, Wu H, et al. (2003). Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Molecul Cancer Res 1:420–7.
  • Yang X, Shi R, Zhang J. (2016). Co-expression and clinical utility of Snail and N-cadherin in papillary thyroid carcinoma. Tumor Biol 37:413–17.
  • Ye X, Tam WL, Shibue T, et al. (2015). Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature 525:256–60.
  • Zhang Y, Zhang H, Wang X, et al. (2012). The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles. Biomaterials 33:679–91.
  • Zheng X, Carstens JL, Kim J, et al. (2015). Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527:525–30.