Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations

References

• Bae SE, Choi DH, Han DH, et al. (2010). Effect of temporally controlled release of dexamethasone on in vivo chondrogenic differentiation of mesenchymal stromal cells. J Control Release 143:23–30.
   PubMed Web of Science ®Google Scholar
• Bile J, Bolzinger MA, Vigne C, et al. (2015). The parameters influencing the morphology of poly(ɛ-caprolactone) microspheres and the resulting release of encapsulated drugs. Int J Pharm 494:152–66.
   PubMed Web of Science ®Google Scholar
• Che E, Gao Y, Wan L, et al. (2015). Paclitaxel/gelatin coated magnetic mesoporous silica nanoparticles: preparation and antitumor efficacy in vivo. Micropor Mesopor Mat 204:226–34.
   Web of Science ®Google Scholar
• Ding DW, Tang XL, Cao XL, et al. (2014). Novel self-assembly endows human serum albumin nanoparticles with an enhanced antitumor efficacy. AAPS Pharm Sci Tech 15:213–22.
   PubMed Web of Science ®Google Scholar
• Du L, Cheng JP, Chi Q, et al. (2006). Biodegradable PLGA microspheres as a sustained release system for a new luteinizing hormone-releasing hormone (LHRH) antagonist. Chem Pharm Bull 54:1259–65.
   PubMed Web of Science ®Google Scholar
• Duan ZQ, Chen CT, Qin J, et al. (2017). Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer. Drug Deliv 24:752–64.
   PubMed Web of Science ®Google Scholar
• Fang K, Yang F, Zhang QY, et al. (2014). Fabrication of nonporous and porous cationic PLGA microspheres. Mater Lett 117:86–9.
   Web of Science ®Google Scholar
• Feng T, Tian H, Xu C, et al. (2014). Synergistic co-delivery of doxorubicin and paclitaxel by porous PLGA microspheres for pulmonary inhalation treatment. Eur J Pharm Biopharm 88:1086–93.
   PubMed Web of Science ®Google Scholar
• Floyd JA, Galperin A, Ratner BD. (2016). Drug encapsulated aerosolized microspheres as a biodegradable, intelligent glioma therapy. J Biomed Mater Res Part Res 104:544–52.
   PubMed Web of Science ®Google Scholar
• Guo J, Gao X, Su L, et al. (2011). Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 32:8010–20.
   PubMed Web of Science ®Google Scholar
• Ho ML, Fu YC, Wang GJ, et al. (2008). Controlled release carrier of BSA made by W/O/W emulsion method containing PLGA and hydroxyapatite. J Control Release 128:142–8.
   PubMed Web of Science ®Google Scholar
• Hou J, Sun E, Zhang ZH, et al. (2017). Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles. Drug Deliv 24:261–9.
   PubMed Web of Science ®Google Scholar
• Jeffery H, Davis SS, O’Hagan DT. (1993). The preparation and characterization of poly(lactide-co-glycolide) microparticles. II. The entrapment of a model protein using a (water-in-oil)-in-water emulsion solvent evaporation technique. Pharm Res 10:362–8.
   PubMed Web of Science ®Google Scholar
• Jollivet C. (2004). Striatal implantation of GDNF releasing biodegradable microspheres promotes recovery of motor function in a partial model of Parkinson's disease. Biomaterials 25:933–42.
   PubMed Web of Science ®Google Scholar
• Joshi G, Kumar A, Sawant K. (2016). Bioavailability enhancement, Caco-2 cells uptake and intestinal transport of orally administered lopinavir-loaded PLGA nanoparticles. Drug Deliv 23:3492–504.
   PubMed Web of Science ®Google Scholar
• Kokai LE, Tan H, Jhunjhunwala S, et al. (2010). Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres. J Control Release 141:168–76.
   PubMed Web of Science ®Google Scholar
• Lee J, Oh YJ, Lee SK, et al. (2010). Facile control of porous structures of polymer microspheres using an osmotic agent for pulmonary delivery. J Control Release 146:61–7.
   PubMed Web of Science ®Google Scholar
• Lin GJ, Jiang GB, Xie YY, et al. (2013). Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes. J Biol Inorg Chem 18:873–82.
   PubMed Web of Science ®Google Scholar
• Menei P, Jadaud E, Faisant N, et al. (2004). Stereotaxic implantation of 5-fluorouracil-releasing microspheres in malignant glioma. Cancer 100:405–10.
   PubMed Web of Science ®Google Scholar
• Mercurio L, Cecchetti S, Ricci A, et al. (2017). Phosphatidylcholine-specific phospholipase C inhibition down-regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells. PLoS One 12:1–19.
   Web of Science ®Google Scholar
• Murai S, Ichikawa T, Kurozumi K, et al. (2016). Quantitative analysis of brain edema in patients with malignant glioma treated with BCNU wafers. J Clin Neurosci 33:148–53.
   PubMed Web of Science ®Google Scholar
• Naraharisetti PK, Ong BYS, Xie JW, et al. (2007). In vivo performance of implantable biodegradable preparations delivering paclitaxel and etanidazole for the treatment of glioma. Biomaterials 28:886–94.
   PubMed Web of Science ®Google Scholar
• Navarria P, Pessina F, Cozzi L, et al. (2016). Can advanced new radiation therapy technologies improve outcome of high grade glioma (HGG) patients? Analysis of 3D-conformal radiotherapy (3DCRT) versus volumetric-modulated arc therapy (VMAT) in patients treated with surgery, concomitant and adjuvant chemo-radiotherapy. BMC Cancer 16:362–71.
   PubMed Web of Science ®Google Scholar
• Nikanjam M, Gibbs AR, Hunt CA, et al. (2007). Synthetic nano-LDL with paclitaxel oleate as a targeted drug delivery vehicle for glioblastoma multiforme. J Control Release 124:163–71.
   PubMed Web of Science ®Google Scholar
• Obayemi JD, Danyuo Y, Dozie-Nwachukwu S, et al. (2016). PLGA-based microparticles loaded with bacterial-synthesized prodigiosin for anticancer drug release: effects of particle size on drug release kinetics and cell viability. Mater Sci Eng C Mater Biol Appl 66:51–65.
   PubMed Web of Science ®Google Scholar
• Perez E, Martinez A, Teijon C, et. al. (2015). Blanco, Improved antitumor effect of paclitaxel administered in vivo as pH and glutathione-sensitive nanohydrogels. Int J Pharm 492:10–19.
   PubMed Web of Science ®Google Scholar
• Pessina F, Navarria P, Cozzi L, et al. (2016). Value of surgical resection in patients with newly diagnosed Grade III glioma treated in a multimodal approach: surgery, chemotherapy and radiotherapy. Ann Surg Oncol 23:3040–6.
   PubMed Web of Science ®Google Scholar
• Shiny J, Goverdhan P, Habibuddin M, et. al. (2013). Development and evaluation of a novel biodegradable sustained release microsphere formulation of paclitaxel intended to treat breast cancer. Int J Pharm Investig 3:119–25.
   PubMedGoogle Scholar
• Strasser A, Cory S, Adams JM. (2011). Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J 30:3667–83.
   PubMed Web of Science ®Google Scholar
• Wang L, Cai M, Liu Y, et al. (2015). Polymer hydrophobicity regulates paclitaxel distribution in microspheres, release profile and cytotoxicity in vitro. Powder Technol 275:77–84.
   Web of Science ®Google Scholar
• Wang R, Gu X, Zhou J, et al. (2016). Green design “bioinspired disassembly-reassembly strategy” applied for improved tumor-targeted anticancer drug delivery.” J Control Release 235:134–46.
   PubMed Web of Science ®Google Scholar
• Wang SY, Shi XD, Gan ZH, et al. (2015). Preparation of PLGA microspheres with different porous morphologies. Chin J Polym Sci 33:128–36.
   Web of Science ®Google Scholar
• Wang XZ, Zhang Q, Lv LY, et al. (2017). Glioma and microenvironment dual targeted nanocarrier for improved antiglioblastoma efficacy. Drug Deliv 24:1401–9.
   PubMed Web of Science ®Google Scholar
• Xie J, Ma YH, Wan M, et al. (2014). Expression of dedifferentiation markers and multilineage markers in U251 glioblastoma cells with silenced EGFR and FGFR genes. Oncol Lett 7:131–6.
   PubMed Web of Science ®Google Scholar
• Yang H, Wang Y. (2016). Five miRNAs considered as molecular targets for predicting neuroglioma. Tumour Biol 37:1051–9.
   PubMedGoogle Scholar
• Yang YY, Chung TS, Ng NP. (2001). Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Biomaterials 22:231–41.
   PubMed Web of Science ®Google Scholar
• Yi X, Lian X, Dong L, et al.. (2015). Co-delivery of pirarubicin and paclitaxel by human serum albumin nanoparticles to enhance antitumor effect and reduce systemic toxicity in breast cancers. Mol Pharmaceutics 12:4085–98.
   PubMed Web of Science ®Google Scholar
• Yu YX, Xu S, You H, et al. (2017). In vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma. Drug Deliv 24:75–82.
   PubMed Web of Science ®Google Scholar
• Zhan C, Gu B, Xie C, et al. (2010). Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect. J Control Release 143:136–42.
   PubMed Web of Science ®Google Scholar
• Zhong Y, Goltsche K, Cheng L, et al. (2016). Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo. Biomaterials 84:250–61.
   PubMed Web of Science ®Google Scholar