Synchronous delivery of oxygen and photosensitizer for alleviation of hypoxia tumor microenvironment and dramatically enhanced photodynamic therapy

References

• Ahmad N, Feyes DK, Agarwal R, et al. (1998). Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis. Proc Natl Acad Sci USA 95:6977–82.
   PubMed Web of Science ®Google Scholar
• Alexis F, Pridgen E, Molnar LK, et al. (2008). Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 5:505–15.
   PubMed Web of Science ®Google Scholar
• Baldwin JM. (1975). Structure and function of haemoglobin. Prog Biophys Mol Biol 29:225–320.
   PubMedGoogle Scholar
• Bergeron M, Yu AY, Solway KE, et al. (1999). Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur J Neurosci 11:4159–70.
   PubMed Web of Science ®Google Scholar
• Busch TM, Wang HW, Wileyto EP, et al. (2010). Increasing damage to tumor blood vessels during motexafin lutetium-PDT through use of low fluence rate. Radiat Res 174:331–40.
   PubMed Web of Science ®Google Scholar
• Carmeliet P, Jain RK. (2000). Angiogenesis in cancer and other diseases. Nature 407:249–57.
   PubMed Web of Science ®Google Scholar
• Castano AP, Mroz P, Hamblin MR. (2006). Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer 6:535–45.
   PubMed Web of Science ®Google Scholar
• Chen H, Tian J, He W, et al. (2015). H2O2-activatable and O2-evolving nanoparticles for highly efficient and selective photodynamic therapy against hypoxic tumor cells. J Am Chem Soc 137:1539–47.
   PubMed Web of Science ®Google Scholar
• Chen W, Zeng K, Liu H, et al. (2017). Cell membrane camouflaged hollow Prussian blue nanoparticles for synergistic photothermal-/chemotherapy of cancer. Adv Funct Mater 27:1605795.
   Web of Science ®Google Scholar
• Cheng Y, Cheng H, Jiang C, et al. (2015). Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy. Nat Commun 6:8785.
   PubMed Web of Science ®Google Scholar
• Curnow A, McIlroy BW, Postle-Hacon MJ, et al. (1999). Light dose fractionation to enhance photodynamic therapy using 5-aminolevulinic acid in the normal rat colon. Photochem Photobiol 69:71–6.
   PubMed Web of Science ®Google Scholar
• Davis ME, Chen Z, Shin DM. (2008). Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 7:771–82.
   PubMed Web of Science ®Google Scholar
• Denko NC. (2008). Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer 8:705–13.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Klitzman B, Braun RD, et al. (2000). Review of methods used to study oxygen transport at the microcirculatory level. Int J Cancer 90:237–55.
   PubMed Web of Science ®Google Scholar
• Dong GC, Hu SX, Zhao GY, et al. (1987). Experimental study on cytotoxic effects of hyperbaric oxygen and photodynamic therapy on mouse transplanted tumor. Chin Med J 100:697–702.
   PubMed Web of Science ®Google Scholar
• Feng L, Cheng L, Dong Z, et al. (2017). Theranostic liposomes with hypoxia-activated prodrug to effectively destruct hypoxic tumors post photodynamic therapy. ACS Nano 11:927–37.
   PubMed Web of Science ®Google Scholar
• Fingar VH, Mang TS, Henderson BW. (1988). Modification of photodynamic therapy-induced hypoxia by fluosol-DA (20%) and carbogen breathing in mice. Cancer Res 48:3350–4.
   PubMed Web of Science ®Google Scholar
• Fleming IN, Manavaki R, Blower PJ, et al. (2015). Imaging tumour hypoxia with positron emission tomography. Br J Cancer 112:238–50.
   PubMed Web of Science ®Google Scholar
• Hall CN, Reynell C, Gesslein B, et al. (2014). Capillary pericytes regulate cerebral blood flow in health and disease. Nature 508:55–60.
   PubMed Web of Science ®Google Scholar
• Henderson BW, Dougherty TJ. (1992). How does photodynamic therapy work? Photochem Photobiol 55:145–57.
   PubMed Web of Science ®Google Scholar
• Henderson BW, Fingar VH. (1987). Relationship of tumour hypoxia and response to photodynamic treatment in an experimental mouse tumour. Cancer Res 47:3110–4.
   PubMed Web of Science ®Google Scholar
• Hockel M, Schlenger K, Aral B, et al. (1996). Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 56:4509–15.
   PubMed Web of Science ®Google Scholar
• Hockel M, Vaupel P. (2001). Tumor hypoxia: definitions and current clinical, biologic, and molecular aspect. J Natl Cancer Inst 93:266–76.
   PubMed Web of Science ®Google Scholar
• Jiang L, Weatherall PT, McColl RW, et al. (2013). Blood oxygenation level-dependent (BOLD) contrast magnetic resonance imaging (MRI) for prediction of breast cancer chemotherapy response: a pilot study. J Magn Reson Imaging 37:1083–92.
   PubMed Web of Science ®Google Scholar
• Jirsa M, Jr, Poucková P, Dolezal J, et al. (1991). Hyperbaric oxygen and photodynamic therapy in tumour-bearing nude mice . Eur J Cancer 27:109.
   PubMed Web of Science ®Google Scholar
• Kami A, Meyer G, Jezzard P, et al. (1995). Functional MRI evidence for adult motor cortex plasticity during motor skill learning. Nature 377:155–8.
   PubMed Web of Science ®Google Scholar
• Kim CK, Park SY, Park BK, et al. (2014). Blood oxygenation level-dependent MR imaging as a predictor of therapeutic response to concurrent chemoradiotherapy in cervical cancer: a preliminary experience. Eur Radiol 24:1514–20.
   PubMed Web of Science ®Google Scholar
• Kimáková P, Solár P, Fecková B, et al. (2017). Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy. Biomed Pharmacother 85:749–55.
   PubMed Web of Science ®Google Scholar
• Leone RD, Horton MR, Powell JD. (2015). Something in the air: hyperoxic conditioning of the tumor microenvironment for enhanced immunotherapy. Cancer Cell 27:435–6.
   PubMed Web of Science ®Google Scholar
• Lindsay H, Huan Y, Du Y, et al. (2016). Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma. J Neurooncol 128:47–56.
   PubMed Web of Science ®Google Scholar
• Liu J, Bu W, Shi J. (2017). Chemical design and synthesis of functionalized probes for imaging and treating tumor hypoxia. Chem Rev 117:6160.
   PubMed Web of Science ®Google Scholar
• Liu Y, Liu Y, Bu W, et al. (2015). Hypoxia induced by upconversion-based photodynamic therapy: towards highly effective synergistic bioreductive therapy in tumors. Angew Chem Int Ed Engl 54:8105.
   PubMed Web of Science ®Google Scholar
• Long H, Li G, Hu Y, et al. (2012). HIF-1α/VEGF signaling pathway may play a dual role in secondary pathogenesis of cervical myelopathy. Med Hypotheses 79:82–4.
   PubMed Web of Science ®Google Scholar
• Luk B, Hu C, Fang R, et al. (2014). Interfacial interactions between natural RBC membranes and synthetic polymeric nanoparticles. Nanoscale 6:2730.
   PubMed Web of Science ®Google Scholar
• Maas AL, Carter SL, Wileyto EP, et al. (2012). Tumor vascular microenvironment determines responsiveness to photodynamic therapy. Cancer Res 72:2079–88.
   PubMed Web of Science ®Google Scholar
• Maier A, Anegg U, Fell B, et al. (2000a). Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus. Lasers Surg Med 26:308–15.
   PubMed Web of Science ®Google Scholar
• Maier A, Anegg U, Tomaselli F, et al. (2000b). Does hyperbaric oxygen enhance the effect of photodynamic therapy in patients with advanced esophageal carcinoma? A clinical pilot study. Endoscopy 32:42–8.
   PubMed Web of Science ®Google Scholar
• Moghissi K, Dixon K, Thorpe JA, et al. (2004). Photodynamic therapy (PDT) for lung cancer: the Yorkshire laser centre experience. Photodiagn Photodyn Ther 1:253–62.
   PubMed Web of Science ®Google Scholar
• Sakai H, Sou K, Horinouchi H, et al. (2009). Review of hemoglobin-vesicles as artificial oxygen carriers. Artif Organs 33:139–45.
   PubMed Web of Science ®Google Scholar
• Song GS, Liang C, Yi X, et al. (2016). Cancer therapy: perfluorocarbon-loaded hollow Bi2Se3 nanoparticles for timely supply of oxygen under near-infrared light to enhance the radiotherapy of cancer. Adv Mater 28:2716–23.
   PubMed Web of Science ®Google Scholar
• Tomaselli F, Maier A, Pinter H, et al. (2001). Photodynamic therapy enhanced by hyperbaric oxygen in acute endoluminal palliation of malignant bronchial stenosis. Eur J Cardiothorac. Surg 19:549–54.
   PubMed Web of Science ®Google Scholar
• Usacheva M, Swaminathan SK, Kirtane AR, Panyam J. (2014). Enhanced photodynamic therapy and effective elimination of cancer stem cells using surfactant-polymer nanoparticles. Mol Pharm 11: 3186–95.
   PubMed Web of Science ®Google Scholar
• Vaupel P, Kallinowski F, Okunieff P. (1989). Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 49:6449–65.
   PubMed Web of Science ®Google Scholar
• Voon SH, Kiew LV, Lee HB, et al. (2014). In vivo studies of nanostructure-based photosensitizers for photodynamic cancer therapy. Small 10:4993–5013.
   PubMed Web of Science ®Google Scholar
• Yee KM, Spivak-Kroizman TR, Powis G. (2009). HIF-1 regulation: not so easy come, easy go. Trends Biochem Sci 33:526–34.
   Web of Science ®Google Scholar
• Yu B, Raher MJ, Volpato GP, et al. (2008). Inhaled nitric oxide enables artificial blood transfusion without hypertension. Circulation 117:1982.
   PubMed Web of Science ®Google Scholar
• Zhao D, Pacheco-Torres J, Hallac RR, et al. (2015). Dynamic oxygen challenge evaluated by NMR T1 and T2*-insights into tumor oxygenation. NMR Biomed 28:937–47.
   PubMed Web of Science ®Google Scholar
• Zhu W, Dong Z, Fu T, et al. (2016). Modulation of hypoxia in solid tumor microenvironment with MnO2 nanoparticles to enhance photodynamic therapy. Adv Funct Mater 26:5490–8.
   Web of Science ®Google Scholar