2,023
Views
23
CrossRef citations to date
0
Altmetric
Research Article

α-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer

, , , , , , & show all
Pages 493-503 | Received 19 Dec 2017, Accepted 30 Jan 2018, Published online: 09 Feb 2018

References

  • Aina OH, Sroka TC, Chen ML, et al. (2002). Therapeutic cancer targeting peptides. Biopolymers 66:184–99.
  • Arredondo J, Nguyen VT, Chernyavsky AI, et al. (2002). Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium. J Cell Biol 159:325–36.
  • Baxter JC, Ramachandra R, Mayne DR, et al. (2014). Functional expression of α7-nicotinic acetylcholine receptors by muscle afferent neurons. J Neurophysiol 112:1549–58.
  • Besse B, Ropert S, Soria JC. (2007). Targeted therapies in lung cancer. Ann Oncol 18:135–42.
  • Cairo CW, Gestwicki JE, Kanai M, Kiessling LL. (2002). Control of multivalent interactions by binding epitope density. J Am Chem Soc 124:1615–9.
  • Catassi A, Paleari L, Servent D, et al. (2008). Targeting alpha7-nicotinic receptor for the treatment of pleural mesothelioma. Eur J Cancer 44:2296–311.
  • Cesario A, Russo P, Nastrucci C, Granone P. (2012). Is α7-nAChR a possible target for lung cancer and malignant pleural mesothelioma treatment? Curr Drug Targets 13:688–94.
  • Cesario A, Russo P, Viaggi S, et al. (2004). Malignant pleural mesothelioma: time for translational research. Lancet Oncol 5:591–2.
  • Du W, Fan Y, He B, et al. (2015). Bionano interactions of mcf-7 breast tumor cells with a transferrin receptor targeted nanoparticle. Mol Pharm 12:1467–76.
  • Egleton RD, Brown KC, Dasgupta P. (2008). Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis. Trends Pharmacol Sci 29:151–8.
  • Ellison M, Gao F, Wang HL, et al. (2004). Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes. Biochemistry 43:16019–26.
  • Gehrmann J, Daly NL, Alewood PF. Craik D (1999). Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance. J Med Chem 42:2364–72.
  • Grozio A, Catassi A, Cavalieri Z, et al. (2007). Nicotine, lung and cancer. Anticancer Agents Med Chem 7:461–6.
  • Grozio A, Paleari L, Catassi A, et al. (2008). Natural agents targeting the α7-nicotinic-receptor in NSCLC: a promising prospective in anti-cancer drug development. Int J Cancer 122:1911–5.
  • He C, Hu Y, Yin L, et al. (2010). Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31:3657–66.
  • Hung RJ, McKay JD, Gaborieau V, et al. (2008). A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452:633–7.
  • Kiss T, Krajcs N, Pirger Z, Hernádi L. (2014). Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. PLoS One 9:1–9.
  • Liu KK, Chen MF, Chen PY, et al. (2008). Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond. Nanotechnology 19:1-10.
  • López MG, Montiel C, Herrero CJ, et al. (1998). Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers. Proc Natl Acad Sci USA 95:14184–9.
  • Maeda H. (2010). Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects. Bioconjugate Chem 21:797–802.
  • Mei D, Lin Z, Fu J, et al. (2015). The use of alpha-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to alpha7 nAChR-overexpressing breast cancer. Biomaterials 42:52–65.
  • Mei H, Shi W, Pang Z, et al. (2010). EGFP-EGF1 protein-conjugated PEG-PLA nanoparticles for tissue factor targeted drug delivery. Biomaterials 31:5619–26.
  • Paleari L, Catassi A, Ciarlo M, et al. (2008a). Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation. Cell Prolif 41:936–59.
  • Paleari L, Grozio A, Cesario A, Russo P. (2008b). The cholinergic system and cancer. Semin Cancer Biol 18:211–7.
  • Paleari L, Cesario A, Fini M, Russo P. (2009). α7-Nicotinic receptor antagonists at the beginning of a clinical era for NSCLC and Mesothelioma? Drug Discov Today 14:822–36.
  • Pereira EF, Alkondon M, McIntosh JM, Albuquerque EX. (1996). Alpha-conotoxin-ImI: a competitive antagonist at alpha-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons. J Pharmacol Exp Ther 278:1472–83.
  • Plummer HK, Dhar M, Schuller HM. (2005). Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells. Respir Res 6:29.
  • Qin C, He B, Dai W, et al. (2014). Inhibition of metastatic tumor growth and metastasis via targeting metastatic breast cancer by chlorotoxin-modified liposomes. Mol Pharm 11:3233–41.
  • Russo P, Catassi A, Cesario A, Servent D. (2006). Development of novel therapeutic strategies for lung cancer: targeting the cholinergic system. Curr Med Chem 13:3493–512.
  • Sato M, Shames DS, Gazdar AF, Minna JD. (2007). A translational view of the molecular pathogenesis of lung cancer. J Thorac Oncol 2:327–43.
  • Schuller HM. (2012). Regulatory role of the α7nAChR in cancer. Curr Drug Targets 13:680–7.
  • Singh S, Pillai S, Chellappan S. (2011). Nicotinic acetylcholine receptor signaling in tumor growth and metastasis. J Oncol 2011:1–11.
  • Skehan P, Storeng R, Scudiero D, et al. (1990). New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82:1107–12.
  • Staros JV, Wright RW, Swingle DM. (1986). Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions. Anal Biochem 156:220–2.
  • Storm G, Belliot SO, Daemen T, Lasic DD. (1995). Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system. Adv Drug Deliv Rev 17:31–48.
  • Surveillance Epidemiology and End Results Program. (2014). Cancer of the Lung and Bronchus – SEER Stat Fact Sheets.
  • Thorgeirsson TE, Geller F, Sulem P, et al. (2008). A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452:638–42.
  • Torre LA, Bray F, Siegel RL, et al. (2015). Global cancer statistics, 2012. CA Cancer J Clin 65:87–108.
  • Torre LA, Siegel RL, Jemal A. (2016). Lung cancer statistics. Adv Exp Med Biol 893:1–19.
  • Trombino S, Cesario A, Margaritora S, et al. (2004). Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway. Cancer Res 64:135–45.
  • Ulens C, Hogg RC, Celie PH, et al. (2006). Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proc Natl Acad Sci USA 103:3615–20.
  • Ween H, Thorin-Hagene K, Andersen E, et al. (2010). Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells. Neurochem Int 57:269–77.
  • Xu S, Olenyuk BZ, Okamoto CT, Hamm-Alvarez SF. (2013). Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances. Adv Drug Deliv Rev 65:121–38.
  • Yu R, Craik DJ, Kaas Q. (2011). Blockade of neuronal alpha7-nAChR by alpha-conotoxin ImI explained by computational scanning and energy calculations. PLoS Comput Biol 7:1–16.
  • Yu R, Kaas Q, Craik DJ. (2012). Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor. J Phys Chem B 116:6097–105.
  • Zhan C, Li B, Hu L, et al. (2011). Micelle-based brain-targeted drug delivery enabled by a nicotine acetylcholine receptor ligand. Angew Chem Int Ed Engl 50:5482–5.
  • Zhang C, Ding XP, Zhao QN, et al. (2016). Role of a7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells. Oncotarget 7:59199–208.
  • Zhang Y, Wang X, Wang J, et al. (2011). Octreotide-modified polymeric micelles as potential carriers for targeted docetaxel delivery to somatostatin receptor overexpressing tumor cells. Pharm Res 28:1167–78.
  • Zia S, Ndoye A, Lee TX, et al. (2000). Receptor-mediated inhibition of keratinocyte migration by nicotine involves modulations of calcium influx and intracellular concentration. J Pharmacol Exp Ther 293:973–81.