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Research Article

Formulation and in vivo assessment of terconazole-loaded polymeric mixed micelles enriched with Cremophor EL as dual functioning mediator for augmenting physical stability and skin delivery

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Pages 484-492 | Received 20 Dec 2017, Accepted 30 Jan 2018, Published online: 07 Feb 2018

References

  • Abdelbary AA, Abd-Elsalam WH, Al-Mahallawi AM. (2016). Fabrication of novel ultradeformable bilosomes for enhanced ocular delivery of terconazole: in vitro characterization, ex vivo permeation, and in vivo safety assessment. Int J Pharm 513:688–96.
  • Abdelbary AA, Al-Mahallawi AM, Abdelrahim ME, Ali AM. (2015). Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration. Int J Nanomedicine 10:6339.
  • Abdou EM, Ahmed NM. (2016). Terconazole proniosomal gels: effect of different formulation factors, physicochemical and microbiological evaluation. J Pharm Drug Deliv Res 5:1–6.
  • Ahad A, Al-Saleh AA, Al-Mohizea AM, et al. (2017). Formulation and characterization of novel soft lipid-based nanoparticles for enhanced transdermal delivery of eprosartan mesylate. Saudi Pharm J 25:1040–6.
  • Al-Mahallawi AM, Abdelbary AA, Aburahma MH. (2015). Investigating the potential of employing bilosomes as a novel vesicular carrier for transdermal delivery of tenoxicam. Int J Pharm 485:329–40.
  • Annadurai G, Ling LY, Lee JF. (2008). Statistical optimization of medium components and growth conditions by response surface methodology to enhance phenol degradation by Pseudomonas putida. J Hazard Mater 151:171–8.
  • Attia ABE, Ong ZY, Hedrick JL, et al. (2011). Mixed micelles self-assembled from block copolymers for drug delivery. Curr Opin Colloid Interface Sci 16:182–94.
  • Attwood D, Booth C, Yeates SG, et al. (2007). Block copolymers for drug solubilisation: relative hydrophobicities of polyether and polyester micelle-core-forming blocks. Int J Pharm 345:35–41.
  • Ayala-Bravo HA, Quintanar-Guerrero D, Naik A, et al. (2003). Effects of sucrose oleate and sucrose laureate on in vivo human stratum corneum permeability. Pharm Res 20:1267–73.
  • Bancroft D, Steven A, Turner R. (2007). Theory and practice of histological techniques. 6 ed. New York: Churchill Livingstone.
  • Bonina FP, Puglia C, Barbuzzi T, et al. (2001). In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac. Eur J Pharm Sci 14:123–34.
  • Cauwenbergh G, Vanden BH. (1989). Terconazole. Pharmacology of a new antimycotic agent. J Reprod Med 34:588–92.
  • Chauhan B, Gupta R. (2004). Application of statistical experimental design for optimization of alkaline protease production from Bacillus sp. RGR-14. Process Biochem 39:2115–22.
  • Chiappetta DA, Sosnik A. (2007). Poly (ethylene oxide)-poly (propylene oxide) block copolymer micelles as drug delivery agents: improved hydrosolubility, stability and bioavailability of drugs. Eur J Pharm Biopharm 66:303–17.
  • Chong JY, Mulet X, Waddington LJ, et al. (2012). High-throughput discovery of novel steric stabilizers for cubic lyotropic liquid crystal nanoparticle dispersions. Langmuir 28:9223–32.
  • Das S, Ng WK, Tan RB. (2012). Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs? Eur J Pharm Biopharm 47:139–51.
  • Date AA, Patravale VB. (2007). Microemulsions: applications in transdermal and dermal delivery. Crit Rev Ther Drug Carrier Syst 24:547–596.
  • Doppalapudi S, Jain A, Chopra DK, Khan W. (2017). Psoralen loaded liposomal nanocarriers for improved skin penetration and efficacy of topical PUVA in psoriasis. Eur J Pharm Biopharm 96:515–29.
  • Du Plessis J, Ramachandran C, Weiner N, Müller D. (1994). The influence of particle size of liposomes on the deposition of drug into skin. Int J Pharm 103:277–82.
  • Dutra LMU, Ribeiro MENP, Cavalcante IM, et al. (2015). Binary mixture micellar systems of F127 and P123 for griseofulvin solubilisation. Polímeros 25:433–9.
  • El-Zahaby SA, Aboughaly MH, Abdelbary GA, El-Gazayerly ON. (2017). Zero order release and bioavailability enhancement of poorly water soluble Vinpocetine from self-nanoemulsifying osmotic pump tablet. Pharm Dev Technol 1–33. https://doi.org/10.1080/10837450.2017.1335321
  • El Zaafarany GM, Awad GA, Holayel SM, Mortada ND. (2010). Role of edge activators and surface charge in developing ultradeformable vesicles with enhanced skin delivery. Int J Pharm 397:164–72.
  • Gao Y, Li LB, Zhai G. (2008). Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin. Colloids Surf B Biointerfaces 64:194–9.
  • Güng S. (2013). New formulation strategies in topical antifungal therapy. Scientific Res 3:56–65.
  • Huber LA, Pereira TA, Ramos DN, et al. (2015). Topical skin cancer therapy using doxorubicin-loaded cationic lipid nanoparticles and iontophoresis. J Biomed Nanotechnol 11:1975–88.
  • James-Smith MA, Hellner B, Annunziato N, Mitragotri S. (2011). Effect of surfactant mixtures on skin structure and barrier properties. Ann Biomed Eng 39:1215–23.
  • Kakkar S, Kaur IP. (2011). Spanlastics-a novel nanovesicular carrier system for ocular delivery. Int J Pharm 413:202–10.
  • Kaushik R, Saran S, Isar J, Saxena RK. (2006). Statistical optimization of medium components and growth conditions by response surface methodology to enhance lipase production by Aspergillus carneus. J Mol Catal B Enzym 40:121–6.
  • Kim KJ, Sung WS, Moon SK, et al. (2008). Antifungal effect of silver nanoparticles on dermatophytes. Am J Microbiol Biotechnol 18:1482–4.
  • Kulthe S, Inamdar N, Choudhari Y, et al. (2011). Mixed micelle formation with hydrophobic and hydrophilic Pluronic block copolymers: implications for controlled and targeted drug delivery. Colloids Surf B Biointerfaces 88:691–6.
  • Kwon GS. (2003). Polymeric micelles for delivery of poorly water-soluble compounds. Crit Rev Ther Drug Carrier Syst 20:357–403.
  • Lee ES, Oh YT, Youn YS, et al. (2011). Binary mixing of micelles using Pluronics for a nano-sized drug delivery system. Colloids Surf B Biointerfaces 82:190–5.
  • Lopez-Pinto J, Gonzalez-Rodriguez M, Rabasco A. (2005). Effect of cholesterol and ethanol on dermal delivery from DPPC liposomes. Int J Pharm 298:1–12.
  • Madheswaran T, Baskaran R, Yong CS, Yoo BK. (2014). Enhanced topical delivery of finasteride using glyceryl monooleate-based liquid crystalline nanoparticles stabilized by cremophor surfactants. AAPS Pharmscitech 15:44–51.
  • Majumdar S, Sloan K. (2007). Topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH). Int J Pharm 332:64–71.
  • Morrow D, Mccarron P, Woolfson A, Donnelly R. (2007). Innovative strategies for enhancing topical and transdermal drug delivery. The Open Drug Delivery Journal 1:36–59.
  • Nalluri BN, Uppuluri C, Devineni J, et al. (2017). Effect of microneedles on transdermal permeation enhancement of amlodipine. Drug Deliv Transl Res 7:383–94.
  • Nour SA, Abdelmalak NS, Naguib MJ, et al. (2016). Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo biodistribution and pharmacodynamics studies. J Drug Deliv 23:3681–95.
  • Oh KT, Bronich TK, Kabanov AV. (2004). Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic® block copolymers. J Control Release 94:411–22.
  • Pamornpathomkul B, Rojanarata T, Opanasopit P, Ngawhirunpat T. (2017). Enhancement of skin permeation and skin immunization of ovalbumin antigen via microneedles. AAPS PharmSciTech 18:2418–26.
  • Shen LN, Zhang YT, Wang Q, et al. (2014). Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes. Int J Pharm 460:280–8.
  • Shinoda K, Nakagawa T, Tamamushi B-I. 2016. Colloidal surfactants: some physicochemical properties. New York: Elsevier.
  • Sun L, Liu Z, Wang L, et al. (2017). Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel. J Control Release 254:44–54.
  • Touitou E, Dayan N, Bergelson L, et al. (2000). Ethosomes: novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release 65:403–18.
  • Verma DD, Verma S, Blume G, Fahr A. (2003). Particle size of liposomes influences dermal delivery of substances into skin. Int J Pharm 258:141–51.
  • Young RL. (1997). Treatment considerations in vulvovaginal candidiasis. Female Patient 22:39–56.
  • Zeisig R, Shimada K, Hirota S, Arndt D. (1996). Effect of sterical stabilization on macrophage uptake in vitro and on thickness of the fixed aqueous layer of liposomes made from alkylphosphocholines. Biochim Biophys Acta 1285:237–45.