Multiseed liposomal drug delivery system using micelle gradient as driving force to improve amphiphilic drug retention and its anti-tumor efficacy

References

• Abraham SA, McKenzie C, Masin D, et al. (2004). In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading. Clin Cancer Res 10:728–38.
   PubMed Web of Science ®Google Scholar
• Baguley BC. (1990). The possible role of electron-transfer complexes in the antitumor anciton of amsacrine analogs. Biophys Chem 35:203–12.
   PubMed Web of Science ®Google Scholar
• Baguley BC, Denny WA, Atwell GJ, et al. (1984). Synthesis, antitumor activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino)phenylamino]-4-acridineca rboxamide. Cancer Res 44:3245–51.
   PubMed Web of Science ®Google Scholar
• Banno B, Ickenstein LM, Chiu GN, et al. (2010). The functional roles of poly(ethylene glycol)-lipid and lysolipid in the drug retention and release from lysolipid-containing thermosensitive liposomes in vitro and in vivo. J Pharm Sci 99:2295–308.
   PubMed Web of Science ®Google Scholar
• Boman NL, Mayer LD, Cullis PR. (1993). Optimization of the retention properties of vincristine in liposomal systems. Biochim Biophys Acta. 1152:253–8.
   PubMed Web of Science ®Google Scholar
• Cammas S, Matsumoto T, Okano T, et al. (1997). Design of functional polymeric micelles as site-specific drug vehicles based on poly (α-hydroxy ethylene oxide-co-β-benzyl L-aspartate) block copolymers. Mater Sci Eng C 4:241–7.
   Web of Science ®Google Scholar
• Comiskey SJ, Heath TD. (1990). Serum-induced leakage of negatively-charged liposomes at nanomolar lipid concentrations. Biochemistry 29:3626–31.
   PubMed Web of Science ®Google Scholar
• Covey JM, Kohn KW, Kerrigan D, et al. (1988). Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)-methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity. Cancer Res 48:860–5.
   PubMed Web of Science ®Google Scholar
• Deng C, Jiang Y, Cheng R, et al. (2012). Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: promises, progress and prospects. Nano Today 7:467–80.
   Web of Science ®Google Scholar
• Edwards K, Johnsson M, Karlsson G, et al. (1997). Effect of polyethyleneglycol-phospholipids on aggregate structure in preparations of small unilamellar liposomes. Biophysical J 73:258–66.
   PubMed Web of Science ®Google Scholar
• Greish K, Sawa T, Fang J, et al. (2004). SMA–doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours. J Control Release 97:219–30.
   PubMed Web of Science ®Google Scholar
• Gubernator J. (2011). Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity. Expert Opin Drug Deliv 8:565–80.
   PubMed Web of Science ®Google Scholar
• Kim JY, Lee H, Oh KS, et al. (2013). Multilayer nanoparticles for sustained delivery of exenatide to treat type 2 diabetes mellitus. Biomaterials 34:8444–9.
   PubMed Web of Science ®Google Scholar
• Lee RJ, Wang S, Turk MJ, et al. (1998). The effects of pH and intraliposomal buffer strength on the rate of liposome content release and intracellular drug delivery. Biosci Rep 18:69–78.
   PubMed Web of Science ®Google Scholar
• Liu X, Sun W, Zhang B, et al. (2013). Clarithromycin-loaded liposomes offering high drug loading and less irritation. Int J Pharm 443:318–27.
   PubMed Web of Science ®Google Scholar
• Liu J, Zeng F, Allen C. (2005). Influence of serum protein on polycarbonate-based copolymer micelles as a delivery system for a hydrophobic anti-cancer agent. J Control Release 103:481–97.
   PubMed Web of Science ®Google Scholar
• Maurer-Spurej E, Wong KF, Maurer N, et al. (1999). Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochim Biophys Acta 1416:1–10.
   PubMed Web of Science ®Google Scholar
• Mikhail AS, Allen C. (2009). Block copolymer micelles for delivery of cancer therapy: transport at the whole body, tissue and cellular levels. J Control Release 138:214–23.
   PubMed Web of Science ®Google Scholar
• Miller T, Breyer S, Van CG, et al. (2013). Premature drug release of polymeric micelles and its effects on tumor targeting. Int J Pharm 445:117–24.
   PubMed Web of Science ®Google Scholar
• Oh KS, Lee H, Kim JY, et al. (2013). The multilayer nanoparticles formed by layer by layer approach for cancer-targeting therapy. J Control Release 165:9–15.
   PubMed Web of Science ®Google Scholar
• Permprasert J, Devahastin S. (2005). Evaluation of the effects of some additives and pH on surface tension of aqueous solutions using a drop-weight method. J Food Eng 70:219–26.
   Web of Science ®Google Scholar
• Ravindra P. (2007). A critical review: surface and interfacial tension measurement by the drop weight method. Chem Eng Commun 195:889–924.
   Web of Science ®Google Scholar
• Reimhult E. (2014). Nanoparticle-triggered release from lipid membrane vesicles. N Biotechnol 32:665–72.
   PubMed Web of Science ®Google Scholar
• See E, Zhang W, Liu J, et al. (2014). Physicochemical characterization of asulacrine towards the development of an anticancer liposomal formulation via active drug loading: stability, solubility, lipophilicity and ionization. Int J Pharm 473:528–35.
   PubMed Web of Science ®Google Scholar
• Siiman LA, Lumeau J, Glebov LB. (2009). Porous nanoparticle supported lipid bilayers (protocells) as delivery vehicles. J Am Chem Soc 131:1354–5.
   PubMed Web of Science ®Google Scholar
• Silvander M, Johnsson M, Edwards K. (1998). Effects of PEG-lipids on permeability of phosphatidylcholine/cholesterol liposomes in buffer and in human serum. Chem Phys Lipids 97:15–26.
   PubMed Web of Science ®Google Scholar
• Sklarin NT, Wiernik PH, Grove WR, et al. (1992). A phase II trial of CI-921 in advanced malignancies. Invest New Drugs 10:309–12.
   PubMed Web of Science ®Google Scholar
• Sunoqrot S, Bugno J, Lantvit D, et al. (2014). Prolonged blood circulation and enhanced tumor accumulation of folate-targeted dendrimer-polymer hybrid nanoparticles. J Control Release 191:115–22.
   PubMed Web of Science ®Google Scholar
• Wong C, Stylianopoulos T, Cui J, et al. (2011). Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc National Academy Sci 108:2426–31.
   PubMed Web of Science ®Google Scholar
• Xin Y, Qi Q, Mao Z, et al. (2017). PLGA nanoparticles introduction into mitoxantrone-loaded ultrasound-responsive liposomes: in vitro and in vivo investigations. Int J Pharm 528:47–54.
   PubMed Web of Science ®Google Scholar
• Xu X, Khan MA, Burgess DJ. (2012). Predicting hydrophilic drug encapsulation inside unilamellar liposomes. Int J Pharm 423:410–8.
   PubMed Web of Science ®Google Scholar
• Yuk SH, Oh KS, Koo H, et al. (2011). Multi-core vesicle nanoparticles based on vesicle fusion for delivery of chemotherapic drugs. Biomaterials 32:7924.
   PubMed Web of Science ®Google Scholar
• Zhang W, Falconer JR, Baguley BC, et al. (2016). Improving drug retention in liposomes by aging with the aid of glucose. Int J Pharm 505:194–203.
   PubMed Web of Science ®Google Scholar
• Zhang W, Wang G, Falconer JR, et al. (2015a). Strategies to maximize liposomal drug loading for a poorly water-soluble anticancer drug. Pharm Res 32:1451–61.
   PubMed Web of Science ®Google Scholar
• Zhang W, Wang G, See E, et al. (2015b). Post-insertion of poloxamer 188 strengthened liposomal membrane and reduced drug irritancy and in vivo precipitation, superior to PEGylation. J Control Release 203:161–9.
   PubMed Web of Science ®Google Scholar