Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic evaluation in rabbits

References

• Abdelbary G, El-gendy N. (2008). Niosome-encapsulated gentamicin for ophthalmic controlled delivery. AAPS Pharm SciTech 9:740–7.
   PubMed Web of Science ®Google Scholar
• Abdelbary GA, Amin MM, Zakaria MY. (2017). Ocular ketoconazole-loaded proniosomal gels: formulation, ex vivo corneal permeation and in vivo studies. Drug Deliv 24:309–19.
   PubMed Web of Science ®Google Scholar
• Abdelkader H, Ismail S, Kamal A, Alany R. (2010). Preparation of niosomes as an ocular delivery system for naltrexone hydrochloride: physicochemical characterization. Pharmazie 65:811–17.
   PubMed Web of Science ®Google Scholar
• Achouri D, Alhanout K, Piccerelle P, Andrieu V. (2013). Recent advances in ocular drug delivery. Drug Dev Ind Pharm 39:1599–617.
   PubMed Web of Science ®Google Scholar
• Akncbay H, Senel S, Ay ZY. (2007). Application of chitosan gel in the treatment of chronic periodontitis. J Biomed Mater Res Part B Appl Biomater 80:290–6.
   PubMed Web of Science ®Google Scholar
• Ammar HO, Salama HA, Ghorab M, Mahmoud AA. (2009). Nanoemulsion as a Potential Ophthalmic Delivery System for Dorzolamide Hydrochloride. AAPS PharmSciTech 10:808–19.
   PubMed Web of Science ®Google Scholar
• Ammar HO, Salama H, Ghorab M, Mahmoud A. (2010). Development of dorzolamide hydrochloride in situ gel nanoemulsion for ocular delivery. Drug Dev Ind Pharm 36:1330–9.
   PubMed Web of Science ®Google Scholar
• Arici MK, Arici DS, Topalkara A, Güler C. (2000). Adverse effects of topical antiglaucoma drugs on the ocular surface. Clin Experiment Ophthalmol 28:113–17.
   PubMed Web of Science ®Google Scholar
• Baudouin C. (1996). Side effects of antiglaucomatous drugs on the ocular surface. Curr Opin Ophthalmol 7:80–6.
   PubMedGoogle Scholar
• Chandraprakash K, Udupa N, Umadevi P, Pillai G. (1990). Pharmacokinetic evaluation of surfactant vesicle-entrapped methotrexate in tumor-bearing mice. Int J Pharm 61:R1–4.
   Web of Science ®Google Scholar
• Dave V, Paliwal S. (2014). A novel approach to formulation factor of aceclofenac eye drops efficiency evaluation based on physicochemical characteristics of in vitro and in vivo permeation. Saudi Pharm J 22:240–5.
   PubMed Web of Science ®Google Scholar
• Doshi U, Xu J. (2009). Effect of viscosity, surface tension and mucoadhesion on ocular residence time of lubricant eye drops. Invest Ophthalmol Vis Sci 50:4641.
   Google Scholar
• El-Hadidy GN, Ibrahim HK, Mohamed MI, El-Milligi MF. (2012). Microemulsions as vehicles for topical administration of voriconazole: formulation and in vitro evaluation. Drug Dev Ind Pharm 38:64–72.
   PubMed Web of Science ®Google Scholar
• Epstein DL, Grant WM. (1977). Carbonic anhydrase inhibitor side effects. Serum chemical analysis. Arch Ophthalmol 95:1378–82.
   PubMed Web of Science ®Google Scholar
• Fahmy AM, El-setouhy DA, Ibrahim AB, et al. (2018). Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies. Drug Deliv 25:12–22.
   PubMed Web of Science ®Google Scholar
• Goodfield M, Davis J, Jeffcoate W. (1982). Acetazolamide and symptomatic metabolic acidosis in mild renal failure. Br Med J (Clin Res Ed) 284:422.
   PubMed Web of Science ®Google Scholar
• Gupta A, Prajapati SK, Balamurugan M, et al. (2007). Design and development of a proniosomal transdermal drug delivery system for captopril. Trop J Pharm Res 6:687–93.
   Web of Science ®Google Scholar
• Gürsoy A, Kut E, Özkırımlı S. (2004). Co-encapsulation of isoniazid and rifampicin in liposomes and characterization of liposomes by derivative spectroscopy. Int J Pharm 271:115–23.
   PubMed Web of Science ®Google Scholar
• Habib BA, AbouGhaly MHH. (2016). Combined mixture-process variable approach: a suitable statistical tool for nanovesicular systems optimization. Expert Opin Drug Deliv 13:1–12.
   PubMed Web of Science ®Google Scholar
• Habib BA, Sayed S, Elsayed GM. (2018). Enhanced transdermal delivery of ondansetron using nanovesicular systems: Fabrication, characterization, optimization and ex-vivo permeation study-Box-Cox transformation practical example . Eur J Pharm Sci 115:352–61.
   PubMed Web of Science ®Google Scholar
• Hasan AA. (2014). Design and in vitro characterization of small unilamellar niosomes as ophthalmic carrier of dorzolamide hydrochloride. Pharm Dev Technol 19:748–54.
   PubMed Web of Science ®Google Scholar
• Hazel G, Akhilesh D, Prabhakara P. (2012). Kamath Jagadish V. Development and evaluation of norfloxacin loaded maltodextrin based proniosomes. Int Res J Pharm 3:176–9.
   Google Scholar
• Janoria KG, Gunda S, Boddu SH, Mitra AK. (2007). Novel approaches to retinal drug delivery. Expert Opin Drug Deliv 4:371–88.
   PubMed Web of Science ®Google Scholar
• Khalil RM, Abdelbary GA, Basha M, et al. (2017). Enhancement of lomefloxacin HCl ocular efficacy via niosomal encapsulation: in vitro characterization and in vivo evaluation. J Liposome Res 27:312–23.
   PubMed Web of Science ®Google Scholar
• Kong M, Chen XG, Xing K, Park HJ. (2010). Antimicrobial properties of chitosan and mode of action: a state of the art review. Int J Food Microbiol 144:51–63.
   PubMed Web of Science ®Google Scholar
• Kouchak M, Bahmandar R, Bavarsad N, Farrahi F. (2016). Ocular Dorzolamide Nanoliposomes for Prolonged IOP Reduction: in-vitro and in-vivo Evaluation in Rabbits. Iran J Pharm Res 15:205–12.
   PubMed Web of Science ®Google Scholar
• Lee B-B, Chan E-S, Ravindra P, Khan TA. (2012). Surface tension of viscous biopolymer solutions measured using the du Nouy ring method and the drop weight methods. Polym Bull 69:471–89.
   Web of Science ®Google Scholar
• Li Q, Li Z, Zeng W, et al. (2014). Proniosome-derived niosomes for tacrolimus topical ocular delivery: in vitro cornea permeation, ocular irritation, and in vivo anti-allograft rejection. Eur J Pharm Sci 62:115–23.
   PubMed Web of Science ®Google Scholar
• Liu T, Guo R. (2007). Investigation of PEG 6000/Tween 80/Span 80/H2O niosome microstructure. Colloid Polym Sci 285:711–13.
   Web of Science ®Google Scholar
• Loftsson T, Jansook P, Stefansson E. (2012). Topical drug delivery to the eye: dorzolamide. Acta Ophthalmol 90:603–8.
   PubMed Web of Science ®Google Scholar
• Manconi M, Sinico C, Valenti D, et al. (2002). Niosomes as carriers for tretinoin. I. Preparation and properties. Int J Pharm 234:237–48.
   PubMed Web of Science ®Google Scholar
• Mishra A, Kapoor A, Bhargava S. (2011). Proniosomal gel as a carrier for improved transdermal drug-delivery. AJPS 1:370–9.
   Google Scholar
• Mokhtar M, Sammour OA, Hammad MA, Megrab NA. (2008). Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes. Int J Pharm 361:104–11.
   PubMed Web of Science ®Google Scholar
• Moore JW, Flanner HH. (1996). Mathematical comparison of dissolution profiles. Pharma Tech 20:64–74.
   Google Scholar
• Paul S, Mondol R, Ranjit S, et al. (2010). Antiglaucomatic niosomal system: recent trend in ocular drug delivery research. Int J Pharm Pharm Sci 2:15–18.
   Google Scholar
• Prabhu P, Koland M, Vijaynarayan K. (2010). Preparation and evaluation of niosomes of brimonidine tartrate as ocular drug delivery system. JPRHC 2:293–301.
   Google Scholar
• Ruckmani K, Sankar V, Sivakumar M. (2010). Tissue distribution, pharmacokinetics and stability studies of zidovudine delivered by niosomes and proniosomes. J Biomed Nanotechnol 6:43–51.
   PubMed Web of Science ®Google Scholar
• Salminen L. (1990). Review: systemic absorption of topically applied ocular drugs in humans. J Ocul Pharmacol Ther 6:243–9.
   Web of Science ®Google Scholar
• Sankhyan A, Pawar PK. (2013). Metformin loaded non-ionic surfactant vesicles: optimization of formulation, effect of process variables and characterization. Daru J Daru 21:7.
   PubMed Web of Science ®Google Scholar
• Sigurdsson HH, Stefánsson E, Gudmundsdóttir E, et al. (2005). Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration. J Control Release 102:255–62.
   PubMed Web of Science ®Google Scholar
• Sayed S, Habib BA, Elsayed GM. (2017). Tri-block co-polymer nanocarriers for enhancement of oral delivery of felodipine: preparation, in vitro characterization and ex vivo permeation. J Liposome Res 1–11 DOI:10.1080/08982104.2017.1327541.
   PubMed Web of Science ®Google Scholar
• Silver LH, Group BCS. (2000). Ocular comfort of brinzolamide 1.0% ophthalmic suspension compared with dorzolamide 2.0% ophthalmic solution: results from two multicenter comfort studies. Surv Ophthalmol 44:S141–S5.
   PubMed Web of Science ®Google Scholar
• Sohrabi S, Haeri A, Mahboubi A, et al. (2016). Chitosan gel-embedded moxifloxacin niosomes: an efficient antimicrobial hybrid system for burn infection. Int J Biol Macromol 85:625–33.
   PubMed Web of Science ®Google Scholar
• Surgue MF. (1996). Review the preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor. J Ocul Pharmacol Ther 12:363–76.
   PubMed Web of Science ®Google Scholar
• Sultana Y, Jain R, Aqil M, Ali A. (2006). Review of ocular drug delivery. Curr Drug Deliv 3:207–17.
   PubMedGoogle Scholar
• Tandale YN, Wagh VD. (2011). Formulation and evaluation of dorzolamide hydrochloride polymeric film. Int J Pharmtech Res 3:1817–24.
   Google Scholar
• Tiffany J, Winter N, Bliss G. (1989). Tear film stability and tear surface tension. Curr Eye Res 8:507–15.
   PubMed Web of Science ®Google Scholar
• Thomas L, Viswanad V. (2012). Formulation and optimization of clotrimazole-loaded proniosomal gel using 3(2) factorial design. Sci Pharm 80:731–48.
   PubMedGoogle Scholar
• Torchilin VP. (2001). Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 73:137–72.
   PubMed Web of Science ®Google Scholar
• Uchegbu IF, Florence AT. (1995). Non-ionic surfactant vesicles (niosomes): physical and pharmaceutical chemistry. Adv Colloid Interface Sci 58:1–55.
   Web of Science ®Google Scholar
• Vicario-de-la-Torre M, Benítez-del-Castillo JM, Vico E, et al. (2014). Design and characterization of an ocular topical liposomal preparation to replenish the lipids of the tear film. Invest Ophthalmol Vis Sci 55:7839–47.
   PubMed Web of Science ®Google Scholar
• Volland C, Wolff M, Kissel T. (1994). The influence of terminal gamma-sterilization on captopril containing poly (D, L-lactide-co-glycolide) microspheres. J Control Release 31:293–305.
   Web of Science ®Google Scholar
• Vora B, Khopade AJ, Jain N. (1998). Proniosome based transdermal delivery of levonorgestrel for effective contraception. J Control Release 54:149–65.
   PubMed Web of Science ®Google Scholar
• Wang G, Wang T. (2008). Oxidative stability of egg and soy lecithin as affected by transition metal ions and pH in emulsion. J Agric Food Chem 56:11424–31.
   PubMed Web of Science ®Google Scholar
• Weyenberg W, Vermeire A, Vandervoort J, et al. (2005). Effects of roller compaction settings on the preparation of bioadhesive granules and ocular minitablets. Eur J Pharm Biopharm 59:527–36.
   PubMed Web of Science ®Google Scholar
• Yadav K, Yadav D, Saroha K, et al. (2010). Proniosomal Gel: a provesicular approach for transdermal drug delivery. Pharm Lett 2:189–98.
   Google Scholar
• Yoshioka T, Sternberg B, Florence AT. (1994). Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60 and 80) and a sorbitan triester (Span 85). Int J Pharm 105:1–6.
   Web of Science ®Google Scholar
• Zignani M, Tabatabay C, Gurny R. (1995). Topical semi-solid drug delivery: kinetics and tolerance of ophthalmic hydrogels. Adv Drug Deliv Rev 16:51–60.
   Web of Science ®Google Scholar
• Zubairu Y, Negi LM, Iqbal Z, Talegaonkar S. (2015). Design and development of novel bioadhesive niosomal formulation for the transcorneal delivery of anti-infective agent: In-vitro and ex-vivo investigations. Asian J Pharm Sci 10:322–30.
   Web of Science ®Google Scholar