2,285
Views
27
CrossRef citations to date
0
Altmetric
Research Article

Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy

, , , , , , , , , , , , & show all
Pages 1403-1413 | Received 13 Apr 2018, Accepted 21 May 2018, Published online: 12 Jun 2018

References

  • An S, Lu X, Zhao W, et al. (2016). Amino acid metabolism abnormity and microenvironment variation mediated targeting and controlled glioma chemotherapy. Small 12:5633–45.
  • Ding L, Zhu X, Wang Y, et al. (2017). Intracellular fate of nanoparticles with polydopamine surface engineering and a novel strategy for exocytosis-inhibiting, lysosome impairment-based cancer therapy. Nano Lett 17:6790–801.
  • Drozdzik M, Groer C, Penski J, et al. (2014). Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine. Mol Pharm 11:3547–55.
  • Fan J, Li Z, Liu X, et al. (2018). Bacteria-mediated tumor therapy utilizing photothermally-controlled TNF-alpha expression via oral administration. Nano Lett 18:2373.
  • Fang L, Wang M, Gou S, et al. (2014). Combination of amino acid/dipeptide with nitric oxide donating oleanolic acid derivatives as PepT1 targeting antitumor prodrugs. J Med Chem 57:1116–20.
  • Ganapathy M, Huang W, Wang H, et al. (1998). Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2. Biochem Biophys Res Commun 246:470–5.
  • Guo X, Meng Q, Liu Q, et al. (2014). Simultaneous determination of three dipeptides (JBP485, Gly-Sar and JBP923) in the cell lysates by liquid chromatography-tandem mass spectrometry: application to identify the function of the PEPT1 transfected cell. Biomed Chromatogr 28:1839–45.
  • Guo X, Meng Q, Liu Q, et al. (2012). Construction, identification and application of HeLa cells stably transfected with human PEPT1 and PEPT2. Peptides 34:395–403.
  • Han X, Sun J, Wang Y, et al. (2015). PepT1, ASBT-linked prodrug strategy to improve oral bioavailability and tissue targeting distribution. Curr Drug Metab 16:71–83.
  • Jiang X, Xin H, Ren Q, et al. (2014). Nanoparticles of 2-deoxy-D-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment. Biomaterials 35:518–29.
  • Kou L, Bhutia Y, Yao Q, et al. (2018). Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types. Front Pharmacol 9:27.
  • Kou L, Yao Q, Sivaprakasam S, et al. (2017). Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB(0,+) to deliver chemotherapeutic agents for colon cancer therapy. Drug Deliv 24:1338–49.
  • Li L, Di X, Wu M, et al. (2017). Targeting tumor highly-expressed LAT1 transporter with amino acid-modified nanoparticles: toward a novel active targeting strategy in breast cancer therapy. Nanomedicine 13:987–98.
  • Li L, Di X, Zhang S, et al. (2016). Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting. Colloids Surf B Biointerfaces 141:260–7.
  • Li J, Guo Y, Kuang Y, et al. (2013). Choline transporter-targeting and co-delivery system for glioma therapy. Biomaterials 34:9142–8.
  • Luo Q, Gong P, Sun M, et al. (2016). Transporter occluded-state conformation-induced endocytosis: amino acid transporter ATB(0,+)-mediated tumor targeting of liposomes for docetaxel delivery for hepatocarcinoma therapy. J Control Release 243:370–80.
  • Pereira C, Araujo F, Granja P, et al. (2014). Targeting membrane transporters and receptors as a mean to optimize orally delivered biotechnological based drugs through nanoparticle delivery systems. Curr Pharm Biotechnol 15:650–8.
  • Qu X, Zou Y, He C, et al. (2018). Improved intestinal absorption of paclitaxel by mixed micelles self-assembled from vitamin E succinate-based amphiphilic polymers and their transcellular transport mechanism and intracellular trafficking routes. Drug Deliv 25:210–25.
  • Ramanathan S, Qiu B, Pooyan S, et al. (2001). Targeted PEG-based bioconjugates enhance the cellular uptake and transport of a HIV-1 TAT nonapeptide. J Control Release 77:199–212.
  • Rosenblum D, Joshi N, Tao W, et al. (2018). Progress and challenges towards targeted delivery of cancer therapeutics. Nat Commun 9:1410.
  • Shan W, Zhu X, Liu M, et al. (2015). Overcoming the diffusion barrier of mucus and absorption barrier of epithelium by self-assembled nanoparticles for oral delivery of insulin. ACS Nano 9:2345–56.
  • Shan W, Zhu X, Tao W, et al. (2016). Enhanced oral delivery of protein drugs using zwitterion-functionalized nanoparticles to overcome both the diffusion and absorption barriers. ACS Appl Mater Interfaces 8:25444–53.
  • Sugawara M, Huang W, Fei Y, et al. (2000). Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci 89:781–9.
  • Sun Y, Sun J, Shi S, et al. (2009). Synthesis, transport and pharmacokinetics of 5'-amino acid ester prodrugs of 1-beta-D-arabinofuranosylcytosine. Mol Pharm 6:315–25.
  • Tang L, Fu L, Zhu Z, et al. (2018). Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation. Drug Deliv 25:862–71.
  • Tao W, Ji X, Xu X, et al. (2017a). Antimonene quantum dots: synthesis and application as near-infrared photothermal agents for effective cancer therapy. Angew Chem Int Ed Engl 56:11656–900.
  • Tao W, Zeng X, Liu T, et al. (2013). Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy. Acta Biomater 9:8910–20.
  • Tao W, Zeng X, Wu J, et al. (2016). Polydopamine-based surface modification of novel nanoparticle-aptamer bioconjugates for in vivo breast cancer targeting and enhanced therapeutic effects. Theranostics 6:470–84.
  • Tao W, Zhang J, Zeng X, et al. (2015). Blended nanoparticle system based on miscible structurally similar polymers: a safe, simple, targeted, and surprisingly high efficiency vehicle for cancer therapy. Adv Healthc Mater 4:1203–14.
  • Tao W, Zhu X, Yu X, et al. (2017b). Black phosphorus nanosheets as a robust delivery platform for cancer theranostics. Adv Mater 29:1603276.
  • Yan Z, Sun J, Chang Y, et al. (2011). Bifunctional peptidomimetic prodrugs of didanosine for improved intestinal permeability and enhanced acidic stability: synthesis, transepithelial transport, chemical stability and pharmacokinetics. Mol Pharm 8:319–29.
  • Zhang Y, Sun J, Gao Y, et al. (2013a). A carrier-mediated prodrug approach to improve the oral absorption of antileukemic drug decitabine. Mol Pharm 10:3195–202.
  • Zhang Y, Sun J, Sun Y, et al. (2013b). Prodrug design targeting intestinal PepT1 for improved oral absorption: design and performance. Curr Drug Metab 14:675–87.
  • Zhu X, Wu J, Shan W, et al. (2016). Polymeric nanoparticles amenable to simultaneous installation of exterior targeting and interior therapeutic proteins. Angew Chem Int Ed Engl 55:3309–12.