(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia

References

• Acevedo KM, Hayne DJ, Mcinnes LE, et al. (2018). The effect of structural modifications to glyoxalbis(thiosemicarbazanoto) copper(II) complexes on cellular copper uptake, copper-mediated ATP7A trafficking and P-glycoprotein mediated efflux. J Med Chem 61:711–23.
   PubMed Web of Science ®Google Scholar
• Baláž P, Fabián M, Pastorek M, et al. (2009). Mechanochemical preparation and anticancer effect of realgar As4S4 nanoparticles. Mater Lett 63:1542–4.
   Web of Science ®Google Scholar
• Bing H, Yuwen T, Xiaoxiong Z, et al. (2013). Bioactive peptides/chitosan nanoparticles enhance cellular antioxidant activity of (-)-epigallocatechin-3-gallate. J Agric Food Chem 61:875–81.
   PubMed Web of Science ®Google Scholar
• Chih-Yeu F, Chung-Chun W, Hui-Yu H, et al. (2015). EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells. Int J Mol Sci 16:2530–58.
   PubMed Web of Science ®Google Scholar
• Dongxu W, Yijun W, Xiaochun W, et al. (2015). Green tea polyphenol (-)-epigallocatechin-3-gallate triggered hepatotoxicity in mice: responses of major antioxidant enzymes and the Nrf2 rescue pathway. Toxicol Appl Pharmacol 283:65–74.
   PubMed Web of Science ®Google Scholar
• Farabegoli F, Papi A, Bartolini G, et al. (2010). (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line. Phytomedicine 17:356–62.
   PubMed Web of Science ®Google Scholar
• Hajipour H, Hamishehkar H, Nazari SAS, et al. (2018). Improved anticancer effects of epigallocatechin gallate using RGD-containing nanostructured lipid carriers. Artif Cells Nanomed Biotechnol 46:1–10.
   Web of Science ®Google Scholar
• Higdon JV, Balz F. (2003). Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. CRC Crit Rev Food Technol 43:89–143.
   PubMed Web of Science ®Google Scholar
• Hsieh DS, Lu HC, Chen CC, et al. (2012). The preparation and characterization of gold-conjugated polyphenol nanoparticles as a novel delivery system. Int J Nanomed 7:1623–33.
   PubMed Web of Science ®Google Scholar
• Jie ZZ, Zhou Q, Zhi WJ, et al. (2011). Validation of the crystal structure of medicinal realgar in China. Spectrosc Spectr Anal 31:291–6.
   Web of Science ®Google Scholar
• Kazushige K. (2005). Comment on inhibitory effect of (-)-epigallocatechin 3-gallate, a polyphenol of green tea, on neutrophil chemotaxis in vitro and in vivo. J Agric Food Chem 53:1307–8.
   Web of Science ®Google Scholar
• Mauro F. (2005). Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5:161–71.
   PubMed Web of Science ®Google Scholar
• Mcculloch D, Brown C, Iland H. (2017). Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectives. Oncotargets Ther Ott 10:1585–601.
   PubMed Web of Science ®Google Scholar
• Moradzadeh M, Roustazadeh A, Tabarraei A, et al. (2017). Epigallocatechin-3-gallate enhances differentiation of acute promyelocytic leukemia cells via inhibition of PML-RARα and HDAC1. Phytother Res Ptr 32.
   Web of Science ®Google Scholar
• Ning N, Peng ZF, Yuan L, et al. (2005). Realgar nano-particles induce apoptosis and necrosis in leukemia cell lines K562 and HL-60. China J China Mater Med 30:136–40.
   Google Scholar
• Orosz Á, Bősze S, Mező G, et al. (2017). Oligo- and polypeptide conjugates of cationic porphyrins: binding, cellular uptake, and cellular localization. Amino Acids 49:1263–14.
   PubMed Web of Science ®Google Scholar
• Philipp S, Marie-Thérèse S, Heike S, et al. (2015). Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: synergism with arabinofuranosylcytosine. Phytomedicine 22:213–22.
   PubMed Web of Science ®Google Scholar
• Ravi S, Nripen C, Ajit Z, et al. (2012). Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer. Proc Natl Acad Sci USA 109:12426–31.
   PubMed Web of Science ®Google Scholar
• Ryan P, Hynes MJ. (2007). The kinetics and mechanisms of the complex formation and antioxidant behaviour of the polyphenols EGCg and ECG with iron(III). J Inorg Biochem 101:585–93.
   PubMed Web of Science ®Google Scholar
• Shanshan W, Kang S, Xin W, et al. (2013). Protonation of epigallocatechin-3-gallate (EGCG) results in massive aggregation and reduced oral bioavailability of EGCG-dispersed selenium nanoparticles. J Agric Food Chem 61:7268–75.
   PubMed Web of Science ®Google Scholar
• Shen Y, Shen ZX, Yan H, et al. (2001). Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosage. Leukemia 15:735–41.
   PubMed Web of Science ®Google Scholar
• Stearns ME, Amatangelo MD, Varma D, et al. (2010). Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice. Am J Pathol 177:3169–79.
   PubMed Web of Science ®Google Scholar
• Sun LM, Zhang CL, Ping L. (2011). Characterization, antimicrobial activity, and mechanism of a high-performance (∼)-epigallocatechin-3-gallate (EGCG)-Cu∼(II)/polyvinyl alcohol (PVA) nanofibrous membrane. J Agric Food Chem 59:5087–92.
   PubMed Web of Science ®Google Scholar
• Sylwia B, Elzbieta G, Teresa W, et al. (2003). Induction of apoptosis by EGCG in selected tumour cell lines in vitro. Folia Histochem Cytobiol 41:229.
   PubMed Web of Science ®Google Scholar
• Tallman MS, Chadi N, Feusner JH, et al. (2002). Acute promyelocytic leukemia: evolving therapeutic strategies. Blood 99:759.
   PubMed Web of Science ®Google Scholar
• Tanaka Y, Komatsu H, Ishii K, et al. (2000). Successful treatment of relapsed and refractory acute promyelocytic leukemia with arsenic trioxide (As2O3). [Rinsho ketsueki] Jpn J Clin Hematol 41:354.
   PubMedGoogle Scholar
• Thompson J, Guichard SM, Cheshire PJ, et al. (2001). Development, characterization and therapy of a disseminated model of childhood neuroblastoma in SCID mice. Cancer Chemother Pharmacol 47:211–21.
   PubMed Web of Science ®Google Scholar
• Ting L, Jiao W, Yancun Y, et al. (2010). (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma. Breast Cancer Res 12:R8–R8.
   PubMed Web of Science ®Google Scholar
• Wang XB, Rong-Gang XI, Shi Y, et al. (2008). Preparation studies of realgar nano-particles. Pharma J Chin People’s Liber Army. 6:12–18.
   Google Scholar
• Yao S, Zhong L, Chen M, et al. (2017). Epigallocatechin-3-gallate promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells via PTEN. Int J Oncol 51:899–906.
   PubMed Web of Science ®Google Scholar
• Ye T, Wang X, Xi R, et al. (2014). Enhanced antitumor activity of realgar mediated by milling it to nanosize. Int J Nanomed 9:745–57.
   PubMed Web of Science ®Google Scholar
• Yong Z, Shao-Xiang W, Ji-Wei M, et al. (2015). EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition. J Neurooncol 121:41–52.
   PubMed Web of Science ®Google Scholar
• Zhan XQ, Zhao FM, Biology DO. (2015). Realgar nanoparticles inhibiting the proliferation of tumor cells in vitro and in vivo. Chin J Cancer Prevent Treat 22:184–8.
   Google Scholar
• Zhong RK, Winkel JGVD, Thepen T, et al. (2001) Cytotoxicity of anti-CD64-ricin A chain immunotoxin against human acute myeloid leukemia cells in vitro and in SCID Mice. Journal of Hematotherapy & Stem Cell Research 10(1):95–105.
   Google Scholar
• Zhang L, Wu S, Wang D, et al. (2014) Epigallocatechin‐3‐gallate (EGCG) in or on nanoparticles: enhanced stability and bioavailability of EGCG encapsulated in nanoparticles or targeted delivery of gold nanoparticles coated with EGCG. Handbook Nanotoxicol Nanomed Stem Cell Toxicol 134–144.
   Google Scholar
• Zhou L, Chen M, Tian L, et al. (2013). Release of polyphenolic drugs from dynamically bonded layer-by-layer films. Acs Appl Mater Interfaces 5:3541–8.
   PubMed Web of Science ®Google Scholar