301
Views
8
CrossRef citations to date
0
Altmetric
Original

Trapping Hemoglobin in Rigid Matrices: Fine Tuning of Oxygen Binding Properties by Modulation of Encapsulation Protocols

, , &
Pages 69-79 | Published online: 24 Aug 2009

REFERENCES

  • Chang, T.M. (2004). Hemoglobin-based red blood cell substitutes. Artif. Organs 28: 789–794.
  • Bone, H.G., Westphal, M. (2005). The prospect of hemoglobin-based blood substitutes: Still a long stony road to go. Crit. Care Med. 33: 694–695.
  • Haney, C.R., Buehler, P.W., Gulati, A. (2000). Purification and chemical modifications of hemoglobin in developing hemoglobin based oxygen carriers. Adv. Drug Deliv. Rev. 40: 153–169.
  • Standl, T. (2001). Haemoglobin-based erythrocyte transfusion substitutes. Expert. Opin. Biol. Ther. 1: 831–843.
  • Burhop, K., Gordon, D., Estep, T. (2004). Review of hemoglobin-induced myocardial lesions. Artif. Cells Blood Substit. Immobil. Biotechnol. 32: 353–374.
  • Jahr, J.S., Varma, N. (2004). PolyHeme. Northfield Laboratories. IDrugs 7: 478–482.
  • Schutte, A.E. (2002). Ethical considerations concerning South Africa's approval of a blood substitute. Ethics Med. 18: 55–62.
  • Vandegriff, K.D., Malavalli, A., Wooldridge, J., Lohman, J., Winslow, R.M. (2003). MP4, a new nonvasoactive PEG-Hb conjugate. Transfusion 43: 509–516.
  • Zheng, S., Zheng, Y., Beissinger, R.L., Fresco, R. (1994). Microencapsulation of hemoglobin in liposomes using a double emulsion, film dehydration/rehydration approach. Biochim. Biophys. Acta. 1196: 123–130.
  • Li, S., Nickels, J., Palmer, A.F. (2005). Liposome-encapsulated actin-hemoglobin (LEAcHb) artificial blood substitutes. Biomaterials 26: 3759–3769.
  • Arifin, D.R., Palmer, A.F. (2005). Polymersome encapsulated hemoglobin: A novel type of oxygen carrier. Biomacromolecules 6: 2172–2181.
  • Phillips, W.T., Klipper, R.W., Awasthi, V.D., Rudolph, A.S., Cliff, R., Kwasiborski, V., Goins, B.A. (1999). Polyethylene glycol-modified liposome-encapsulated hemoglobin: A long circulating red cell substitute. J. Pharmacol. Exp. Ther. 288: 665–670.
  • Arifin, D.R., Palmer, A.F. (2005). Physical properties and stability mechanisms of poly(ethylene glycol) conjugated liposome encapsulated hemoglobin dispersions. Artif. Cells Blood Substit. Immobil. Biotechnol. 33: 137–162.
  • Winslow, R.M. (2005). Targeted O2 delivery by low-p50 hemoglobin: a new basis for hemoglobin-based oxygen carriers. Artif. Cells Blood Substit. Immobil. Biotechnol. 33: 1–12.
  • Bettati, S., Pioselli, B., Campanini, B., Viappiani, C., Mozzarelli, A. (2004). Encyclopedia of Nanoscience and Nanotechnology, American Scientific Publishers: Stevenson Ranch (, CA), USA, pp. 81–103.
  • Bettati, S., Mozzarelli, A. (1997). T state hemoglobin binds oxygen noncooperatively with allosteric effects of protons, inositol hexaphosphate, and chloride. J. Biol. Chem. 272: 32050–32055.
  • Bruno, S., Bonaccio, M., Bettati, S., Rivetti, C., Viappiani, C., Abbruzzetti, S., Mozzarelli, A. (2001). High and low oxygen affinity conformations of T state hemoglobin. Protein Sci. 10: 2401–2407.
  • Dozy, A.M., Kleihauer, E.F., Huisman, T.H. (1968). Studies on the heterogeneity of hemoglobin. 13. Chromatography of various human and animal hemoglobin types on DEAE-Sephadex. J. Chromatogr. 32: 723–727.
  • Rivetti, C., Mozzarelli, A., Rossi, G.L., Henry, E.R., Eaton, W.A. (1993). Oxygen binding by single crystals of hemoglobin. Biochemistry 32: 2888–2906.
  • Dvorak, J.A., Stotler, W.F. (1971). A controlled-environment culture system for high resolution light microscopy. Exp. Cell Res. 68: 144–148.
  • Viappiani, C., Bettati, S., Bruno, S., Ronda, L., Abbruzzetti, S., Mozzarelli, A., Eaton, W.A. (2004). New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. Proc. Natl. Acad. Sci. USA 101: 14414–14419.
  • Samuni, U., Dantsker, D., Juszczak, L.J., Bettati, S., Ronda, L., Mozzarelli, A., Friedman, J.M. (2004). Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels. Biochemistry 43: 13674–13682.
  • Chauvierre, C., Marden, M. C., Vauthier, C., Labarre, D., Couvreur, P., Leclerc, L. (2004). Biomaterials 25: 3081–3086.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.