Effects of Hemoglobin Vesicles, a Liposomal Artificial Oxygen Carrier, on Hematological Responses, Complement and Anaphylactic Reactions in Rats

REFERENCES

• Bunn, H.F., Esham, W.T., Bull, R.W. (1969). The renal handling of hemoglobin. I. Glomerular filtration. J. Exp. Med. 129: 909–923.
   PubMed Web of Science ®Google Scholar
• Martin, W., Villani, G.M., Jothianandan, D., Furchgott, R.F. (1985). Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J. Pharmacol. Exp. Ther. 232: 708–716.
   PubMed Web of Science ®Google Scholar
• Hess, J.R., MacDonald, V.W., Brinkley, W.W. (1993). Systemic and pulmonary hypertension after resuscitation with cell-free hemoglobin. J. Appl. Physiol. 74: 1769–1778.
   PubMed Web of Science ®Google Scholar
• Chang T.M. (1964). Semipermeable microcapsules. Science. 146: 524–525.
   PubMed Web of Science ®Google Scholar
• Chang T.M. (1971). Stabilisation of enzymes by microencapsulation with a concentrated protein solution or by microencapsulation followed by cross-linking with glutaraldehyde. Biochem. Biophys. Res. Commun. 44:1531–1536.
   PubMed Web of Science ®Google Scholar
• Chatterjee, R., Welty, E.V., Walder, R.Y., Pruitt, S.L., Rogers, P.H., Arnone, A., Walder, J.A. (1986). Isolation and characterization of a new hemoglobin derivative cross-linked between the a chains (lysine 99a1-lysine 99a2). J. Biol. Chem. 261: 9929–9937.
   PubMed Web of Science ®Google Scholar
• DeVenuto, F., Zegna, A. (1983). Preparation and evaluation of pyridoxalated-polymerized human hemoglobin. J. Surg. Res. 34: 205–212.
   PubMed Web of Science ®Google Scholar
• Ajisaka, K., Iwashita, Y. (1980). Modification of human hemoglobin with polyethylene glycol: a new candidate for blood substitute. Biochem. Biophys. Res. Commun. 97: 1076–1081.
   PubMed Web of Science ®Google Scholar
• Lieberthal, W., Fuhro, R., Andry, C., Valeri, C.R. (2000). Effects of hemoglobin-based oxygen-carrying solutions in anesthetized rats with accute ischemic renal failure. J. Lab. Clin. Med. 135: 73–81.
   PubMed Web of Science ®Google Scholar
• Raat, N.J., Liu, J.F., Doyle, M.P., Burhop, K.E., Klein, J., Ince, C. (2005). Effects of recombinant-hemoglobin solutions rHb2.0 and rHb1.1 on blood pressure, intestinal blood flow, and gut oxygenation in a rat model of hemorrhagic shock. J. Lab. Clin. Med. 145: 9–11.
   PubMedGoogle Scholar
• Djordjevich, L., Miller, I.F. (1980). Synthetic erythrocytes from lipid encapsulated hemoglobin. Exp. Hematol. 8: 584–592.
   PubMed Web of Science ®Google Scholar
• Gaber, B.P., Farmer, M.C. (1984). Encapsulation of hemoglobin in phospholipid vesicles: Preparation and properties of a red cell surrogate. Prog Clin Biol Res. 165: 179–190.
   PubMedGoogle Scholar
• Hunt, C.A., Burnette, R.R., MacGregor, R.D., Strubbe, A.E., Lau, D.T., Taylor, N., Kiwada, H. (1985). Synthesis and evaluation of a prototypal artificial red cell. Science 230: 1165–1168.
   PubMed Web of Science ®Google Scholar
• Rudolph, A.S., Klipper, R.W., Goins, B., Phillips, W.T. (1991). In vivo biodistribution of a radiolabeled blood substitute: 99mTc-labeled liposome-encapsulated hemoglobin in an anesthetized rabbit. Proc Natl Acad Sci USA. 88: 10976–10980.
   PubMed Web of Science ®Google Scholar
• Phillips, W.T., Klipper, R.W., Awasthi, V.D., Rudolph, A.S., Cliff, R., Kwasiborski, V., Goins, B.A. (1999). Polyethylene glycol-modified liposome-encapsulated hemoglobin: A long circulating red cell substitute. J. Pharmacol Exp. Ther. 288: 665–670.
   PubMed Web of Science ®Google Scholar
• Wakamoto, S., Fujihara, M., Abe, H., Sakai, H., Takeoka, S., Tsuchida, E., Ikeda, H., Ikebuchi, K. (2001). Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on agonist-induced platelet aggregation and RANTES release in vitro. Artif. Cells Blood Substit. Immobil. Biotechnol. 29: 191–201.
   PubMed Web of Science ®Google Scholar
• Wakamoto, S., Fujihara, M., Abe, H., Yamaguchi, M., Takeoka, S., Tsuchida, E., Azuma, H., Ikeda, H. (2005). Effects of hemoglobin vesicles on resting and agonist-stimulated human platelets in vitro. Artif. Cells Blood Substit. Biotechnol. 33: 101–111.
   PubMed Web of Science ®Google Scholar
• Ito, T., Fujihara, M., Abe, H., Yamaguchi, M., Wakamoto, S., Takeoka, S., Sakai, H., Tsuchida, E., Ikeda, H., Ikebuchi, K. (2001). Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on N-formyl-methionyl-leucyl-phenylalanine-induced responses of polymorphonuclear neutrophils in vitro. Artif. Cells Blood Substit. Immobil. Biotechnol. 29: 427–437.
   PubMed Web of Science ®Google Scholar
• Abe, H., Fujihara, M., Ikebuchi, K., Takeoka, S., Tsuchida, E., Harashima, H., Azuma, H., Ikeda, H. (2006). Interaction of hemoglobin vesicles, a cellular-type artificial oxygen carrier, with human plasma: Effects on coagulation, kallikrein-kinin, and complement systems. Artif. Cells Blood Substit. Biotechnol. 34: 1–10.
   PubMed Web of Science ®Google Scholar
• Szebeni, J., Wassef, N.M., Rudolph, A.S., Alving, C.R. (1996). Complement activation in human serum by liposome-encapsulated hemoglobin: The role of natural anti-phospholipid antibodies. Biochim. Biophys. Acta 1285: 127–130.
   PubMed Web of Science ®Google Scholar
• Szebeni, J., Baranyi, L., Savay, S., Bodo, M., Morse, D.S., Basta, M., Stahl, G.L., Bunger, R., Alving, C.R. (2000). Liposome-induced pulmonary hypertension: Properties and mechanism of a complement-mediated pseudoallergic reaction. Am. J. Physiol. Heart Circ. Physiol. 279: H1319–H1328.
   PubMed Web of Science ®Google Scholar
• Laverman, P., Boerman, O.C., Oyen, W.J.G., Corstens, F.H.M., Storm, G. (2001). In vivo applications of PEG liposomes: Unexpected observations. Crit. Rev. Ther. Drug Carrier Syst. 18: 551–566.
   PubMed Web of Science ®Google Scholar
• Sakai, H., Takeoka, S., Wettstein, R., Tsai, A.G., Intaglietta, M., Tsuchida, E. (2002). Systemic and microvascular responses to hemorrhagic shock and resuscitation with Hb vesicles. Am. J. Physiol. Heart Circ. Physiol. 283: H1191–1199.
   PubMed Web of Science ®Google Scholar
• Sakai, H., Masada, Y., Horinouchi, H., Yamamoto, M., Ikeda, E., Takeoka, S., Kobayashi, K., Tsuchida, E. (2004). Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats. Crit. Care Med. 32: 539–545.
   PubMed Web of Science ®Google Scholar
• Yoshizu, A., Izumi, Y., Park, S., Sakai, H., Takeoka, S., Horinouchi, H., Ikeda, E., Tsuchida, E., Kobayashi, K. (2004). Hemorrhagic shock resuscitation with an artificial oxygen carrier, hemoglobin vesicle maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor-alpha. ASAIO J. 50: 458–463.
   PubMed Web of Science ®Google Scholar
• Sakai, H., Horinouchi, H., Masada, Y., Takeoka, S., Ikeda, E., Takaori, M., Kobayashi, K., Tsuchida, E. (2004). Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model. Biomaterials. 25: 4317–4325.
   PubMedGoogle Scholar
• Sakai, H., Takeoka, S., Park, S.I., Kose, T., Nishide, H., Izumi, Y., Yoshizu, A., Kobayashi, K., Tsuchida, E. (1997). Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats. Bioconjug. Chem. 8: 23–30.
   PubMed Web of Science ®Google Scholar
• Sou, K., Naito, Y., Endo, T., Takeoka, S., Tsuchida, E. (2003). Effective encapsulation of proteins into size-controlled phospholipid vesicles using freeze-thawing and extrusion. Biotechnol. Prog. 19: 1547–1552.
   PubMed Web of Science ®Google Scholar
• Abe, H., Ikebuchi, K., Hirayama, J., Fujihara, M., Takeoka, S., Sakai, H., Tsuchida, E., Ikeda, H. (2001). Virus inactivation in hemoglobin solution by heat treatment. Artif. Cells Blood Substit. Immobil. Biotechnol. 29: 381–388.
   PubMed Web of Science ®Google Scholar
• Singh, P., Daniels, M., Winsett, D.W., Richards, J., Doerfler, D., Hatch, G., Adler, K.B., Gilmour, M.I. (2003). Phenotypic comparison of allergic airway responses to house dust mite in three rat strains. Am. J. Physiol. Lung Cell Mol. Physiol. 284: L588–L598.
   PubMedGoogle Scholar
• Kurebayashi, Y., Honda, Y. (1991). Protection by 16,16-dimethyl prostaglandin E2 and dibutyryl cyclic AMP against complement-mediated hepatic necrosis in rats. Hepatology 14: 545–550.
   PubMed Web of Science ®Google Scholar
• Rabinovici, R., Rudolph, A.S., Feuerstein, G. (1989). Characterization of hemodynamic, hematologic, and biochemical responses to administration of liposome-encapsulated hemoglobin in the conscious, freely moving rat. Circulatory Shock 29: 115–132.
   PubMedGoogle Scholar
• Rudolph, A.S., Cliff, R.O., Spargo, B.J., Spielberg, H. (1994). Transient changes in the mononuclear phagocyte system following administration of the blood substitute liposome-encapsulated haemoglobin. Biomaterials 15: 796–804.
   PubMed Web of Science ®Google Scholar
• Cooper, D.A., Tindall, B., Wilson, E.J., Imrie, A.A., Penny, R. (1988). Characterization of T lymphocyte responses during primary infection with human immunodeficiency virus. J. Infect. Dis. 157: 889–896.
   PubMed Web of Science ®Google Scholar
• Cunningham, C.M., Kingzette, M., Richards, R.L., Alving, C.R., Lint, T.F., Gewurz, H. (1979). Activation of human complement by liposomes: A model for membrane activation of the alternative pathway. J. Immunol. 122: 1237–1242.
   PubMedGoogle Scholar
• Chonn, A., Cullis, P.R., Devine, D.V. (1991). The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes. J. Immunol. 146: 4234–4241.
   PubMed Web of Science ®Google Scholar
• Devine, D.V., Wong, K., Serrano, K., Chonn, A., Cullis, P.R. (1994). Liposome-complement interactions in rat serum: Implications for liposome survival studies. Biochim. Biophys. Acta 1191: 43–51.
   PubMed Web of Science ®Google Scholar
• Alving, C.R., Richards, R.L., Guirguis, A.A. (1977). Cholesterol-dependent human complement activation resulting in damage to liposomal model membranes. J. Immunol. 118: 342–347.
   PubMedGoogle Scholar
• Laing, R.B., Milne, L.J., Leen, C.L., Malcolm, G.P., Steers, A.J. (1994). Anaphylactic reactions to liposomal amphotericin. Lancet 344: 682.
   PubMed Web of Science ®Google Scholar
• Ringden, O., Andstrom, E., Remberger, M., Svahn, B.M., Tollemar, J. (1994). Allergic reactions and other rare side-effects of liposomal amphotericin. Lancet 344: 1156–1157.
   PubMed Web of Science ®Google Scholar
• Szebeni, J., Wassef, N.M., Spielberg, H., Rudolph, A.S., Alving, C.R. (1994). Complement activation in rats by liposomes and liposome-encapsulated hemoglobin: Evidence for anti-lipid antibodies and alternative pathway activation. Biochem. Biophys. Res. Commun. 205: 255–263.
   PubMed Web of Science ®Google Scholar