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Articles

Proapoptotic Nitric Oxide Production in Amyloid β Protein-Treated Cerebral Microvascular Endothelial Cells

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Pages 89-97 | Received 17 Jun 2006, Accepted 26 Jul 2006, Published online: 10 Jul 2009

REFERENCES

  • Akama K T, Van Eldik L J. Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1β- and tumor necrosis factor-α (TNFα)-dependent, and involves a TNFα receptor-associated factor- and NFκ B-inducing kinase-dependent signaling mechanism. J Biol Chem 2000; 275: 7918–7924
  • Andrew P J, Mayer B. Enzymatic function of nitric oxide synthases. Cardiovasc Res 1999; 43: 521–531
  • Arstall M A, Sawyer D B, Fukazawa R, Kelly R A. Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res 1999; 85: 829–840
  • Attems J, Jellinger K A. Only cerebral capillary amyloid angiopathy correlates with Alzheimer pathology: a pilot study. Acta Neuropathol (Berl) 2004; 107: 83–90
  • Bal-Price A, Brown G C. Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J Neurochem 2000; 75: 1455–1464
  • Berg L, McKeel D W, Jr., Miller J P, Baty J, Morris J C. Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older. Arch Neurol 1993; 50: 349–358
  • Bredt D S. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radic Res 1999; 31: 577–596
  • del a Torre J C, Stefano G B. Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide. Brain Res Brain Res Rev 2000; 34: 119–136
  • Floyd R A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Med 1999; 222: 236–245
  • Grammas P, Moore P, Weigel P H. Microvessels from Alzheimer's disease brains kill neurons in vitro. Am J Pathol 1999; 154: 337–342
  • Grammas P, Yamada M, Zlokovic B. The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's disease. J Alzheimers Dis 2002; 4: 217–223
  • Haas J, Storch-Hagenlocher B, Biessmann A, Wildemann B. Inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with β -amyloid 1-42 in vitro. Neurosci Lett 2002; 322: 121–125
  • Heneka M T, Loschmann P A, Gleichmann M, Weller M, Schulz J B, Wullner U, Klockgether T. Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-α /lipopolysaccharide. J Neurochem 1998; 71: 88–94
  • Heneka M T, Wiesinger H, Dumitrescu-Ozimek L, Riederer P, Feinstein D L, Klockgether T. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. J Neuropathol Exp Neurol 2001; 60: 906–916
  • Hirakawa M, Oike M, Masuda K, Ito Y. Tumor cell apoptosis by irradiation-induced nitric oxide production in vascular endothelium. Cancer Res 2002; 62: 1450–1457
  • Ishii K, Muelhauser F, Liebl U, Picard M, Kuhl S, Penke B, Bayer T, Wiessler M, Hennerici M, Beyreuther K, Hartmann T, Fassbender K. Subacute NO generation induced by Alzheimer's β -amyloid in the living brain: reversal by inhibition of the inducible NO synthase. FASEB J 2000; 14: 1485–1489
  • Kim W, Hecht M H. Sequence determinants of enhanced amyloidogenicity of Alzheimer Aβ 42 peptide relative to Aβ 40. J Biol Chem 2005; 280: 35069–35076
  • Kimura C, Oike M, Kashiwagi S, Ito Y. Effects of acute glucose overload on histamine H2 receptor-mediated Ca2+ mobilization in bovine cerebral endothelial cells. Diabetes 1998; 47: 104–112
  • Kimura C, Oike M, Koyama T, Ito Y. Impairment of endothelial nitric oxide production by acute glucose overload. Am J Physiol 2001; 280: E171–E178
  • Kimura C, Oike M, Ohnaka K, Nose Y, Ito Y. Constitutive nitric oxide production in bovine aortic and brain microvascular endothelial cells: a comparative study. J Physiol 2004; 554: 721–730
  • Kojima H, Nakatsubo N, Kikuchi K, Kawahara S, Kirino Y, Nagoshi H, Hirata Y, Nagano T. Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins. Anal Chem 1998; 70: 2446–2453
  • Levecque C, Elbaz A, Clavel J, Richard F, Vidal J S, Amouyel P, Tzourio C, Alperovitch A, Chartier-Harlin M C. Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study. Hum Mol Genet 2003; 12: 79–86
  • Lipton S A. Neuronal protection and destruction by NO. Cell Death Differ 1999; 6: 943–951
  • Meda L, Cassatella M A, Szendrei G I, Otvos L, Jr., Baron P, Villalba M, Ferrari D, Rossi F. Activation of microglial cells by β-amyloid protein and interferon-γ. Nature 1995; 374: 647–650
  • Miao J, Xu F, Davis J, Otte-Holler I, Verbeek M M, Van Nostrand W E. Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β precursor protein. Am J Pathol 2005; 167: 505–515
  • Moncada S, Palmer R M, Higgs E A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109–142
  • Mulligan S J, MacVicar B A. Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature 2004; 431: 195–199
  • Razavi H M, Hamilton J A, Feng Q. Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. Pharmacol Ther 2005; 106: 147–162, Epub 2005 Jan 2012
  • Rhodin J A, Thomas T. A vascular connection to Alzheimer's disease. Microcirculation 2001; 8: 207–220
  • Rodrigo J, Fernandez-Vizarra P, Castro-Blanco S, Bentura M L, Nieto M, Gomez-Isla T, Martinez-Murillo R, MartInez A, Serrano J, Fernandez A P. Nitric oxide in the cerebral cortex of amyloid-precursor protein (SW) Tg2576 transgenic mice. Neuroscience 2004; 128: 73–89
  • Sasaki S, Shibata N, Komori T, Iwata M. iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis. Neurosci Lett 2000; 291: 44–48
  • Stefano G B, Salzet M, Magazine H I, Bilfinger T V. Antagonism of LPS and IFN-γ induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. J Cardiovasc Pharmacol 1998; 31: 813–820
  • Wallace M N, Geddes J G, Farquhar D A, Masson M R. Nitric oxide synthase in reactive astrocytes adjacent to β -amyloid plaques. Exp Neurol 1997; 144: 266–272
  • Xia Y, Tsai A L, Berka V, Zweier J L. Superoxide generation from endothelial nitric-oxide synthase. A Ca2 +/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 1998; 273: 25804–25808
  • Yankner B A, Duffy L K, Kirschner D A. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 1990; 250: 279–282
  • Zeng C, Lee J T, Chen H, Chen S, Hsu C Y, Xu J. Amyloid-β peptide enhances tumor necrosis factor-α-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes. J Neurochem 2005; 94: 703–712
  • Zhang W Y, Gotoh T, Oyadomari S, Mori M. Coinduction of inducible nitric oxide synthase and arginine recycling enzymes in cytokine-stimulated PC12 cells and high output production of nitric oxide. Brain Res Mol Brain Res 2000; 83: 1–8
  • Zhang Z, Shen H M, Zhang Q F, Ong C N. Critical role of GSH in silica-induced oxidative stress, cytotoxicity, and genotoxicity in alveolar macrophages. Am J Physiol 1999; 277: L743–L748
  • Zonta M, Angulo M C, Gobbo S, Rosengarten B, Hossmann K A, Pozzan T, Carmignoto G. Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat Neurosci 2003; 6: 43–50

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