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Articles

Abrupt Reoxygenation of Microvascular Endothelial Cells After Hypoxia Activates ERK1/2 and JNK1, Leading to NADPH Oxidase-Dependent Oxidant Production

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Pages 125-136 | Received 04 May 2006, Accepted 23 Aug 2006, Published online: 10 Jul 2009

REFERENCES

  • Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: an update. Biochem J 2003; 371: 199–204
  • Bolon M L, Ouellette Y, Li F, Tyml K. Abrupt reoxygenation following hypoxia reduces electrical coupling between endothelial cells of wild-type but not connexin40 null mice in oxidant- and PKA-dependent manner. FASEB J 2005; 19: 1725–1727
  • Brecht S, Kirchhof R, Chromik A, Willesen M, Nicolaus T, Raivich G, Wessig J, Waetzig V, Goetz M, Claussen M, Pearse D, Kuan C Y, Vaudano E, Behrens A, Wagner E, Flavell R A, Davis R J, Herdegen T. Specific pathophysiological functions of JNK isoforms in the brain. Eur J Neurosci 2005; 21: 363–377
  • Cai H, Griendling K K, Harrison D G. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 2003; 24: 471–478
  • Dewas C, Fay M, Gougerot-Pocidalo M A, El-Benna J. The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils. J Immunol 2000; 165: 5238–5244
  • Dougherty C J, Kubasiak L A, Frazier D P, Li H, Xiong W C, Bishopric N H, Webster K A. Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation. FASEB J 2004; 18: 1060–1070
  • Fan C, Katsuyama M, Nishinaka T, Yabe-Nishimura C. Transactivation of the EGF receptor and a PI3 kinase-ATF-1 pathway is involved in the upregulation of NOX1, a catalytic subunit of NADPH oxidase. FEBS Lett 2005; 579: 1301–1305
  • Farivar A S, Kinnon-Patterson B C, Barnes A D, McCourtie A S, Mulligan M S. Cyclosporine modulates the response to hypoxia-reoxygenation in pulmonary artery endothelial cells. Ann Thorac Surg 2005; 79: 1010–1016
  • Gorin Y, Ricono J M, Wagner B, Kim N H, Bhandari B, Choudhury G G, Abboud H E. Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells. Biochem J 2004; 381: 231–239
  • Griendling K K, Sorescu D, Lassegue B, Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 2000; 20: 2175–2183
  • Griffith T M. Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?. Br J Pharmacol 2004; 141: 881–903
  • Hansen P R. Inflammatory alterations in the myocardial microcirculation. J Mol Cell Cardiol 1998; 30: 2555–2559
  • Hashimoto Y, Itoh K, Nishida K, Okano T, Miyazawa Y, Okinaga K. Rapid superoxide production by endothelial cells and their injury upon reperfusion. J Surg Res 1994; 57: 693–697
  • Ihnken K, Morita K, Buckberg G D, Winkelmann B, Beyersdorf F, Sherman M P. Reduced oxygen tension during cardiopulmonary bypass limits myocardial damage in acute hypoxic immature piglet hearts. Eur J Cardiothorac Surg 1996; 10: 1127–1134
  • Irwin D C, Tissot van Patot M C, Tucker A, Bowen R. Direct ANP inhibition of hypoxia-induced inflammatory pathways in pulmonary microvascular and macrovascular endothelial monolayers. Am J Physiol Lung Cell Mol Physiol 2005; 288: L849–L859
  • Jerome S N, Kong L, Korthuis R J. Microvascular dysfunction in postischemic skeletal muscle. J Invest Surg 1994; 7: 3–16
  • Khan T A, Bianchi C, Ruel M, Voisine P, Li J, Liddicoat J R, Sellke F W. Mitogen-activated protein kinase inhibition and cardioplegia-cardiopulmonary bypass reduce coronary myogenic tone. Circulation 2003; 108: II348–II353, (Suppl 1)
  • Korthuis R J, Smith J K, Carden D L. Hypoxic reperfusion attenuates postischemic microvascular injury. Am J Physiol 1989; 256: H315–H319
  • Kurjiaka D T, Segal S S. Conducted vasodilation elevates flow in arteriole networks of hamster striated muscle. Am J Physiol 1995; 269: H1723–H1728
  • Li C, Jackson R M. Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 2002; 282: C227–C241
  • Lidington D, Ouellette Y, Tyml K. Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway. J Cell Physiol 2000; 185: 117–125
  • Mohazzab H, Kaminski P M, Wolin M S. Lactate and PO2 modulate superoxide anion production in bovine cardiac myocytes: potential role of NADH oxidase. Circulation 1997; 96: 614–620
  • Oeckler R A, Arcuino E, Ahmad M, Olson S C, Wolin M S. Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase. Am J Physiol Lung Cell Mol Physiol 2005; 288: L1017–L1025
  • Parinandi N L, Kleinberg M A, Usatyuk P V, Cummings R J, Pennathur A, Cardounel A J, Zweier J L, Garcia J G, Natarajan V. Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am J Physiol Lung Cell Mol Physiol 2003; 284: L26–L38
  • Piacentini L, Karliner J S. Altered gene expression during hypoxia and reoxygenation of the heart. Pharmacol Ther 1999; 83: 21–37
  • Rose K, Ouellette Y, Bolon M, Tyml K. Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway. J Cell Physiol 2005; 204: 131–138
  • Roy S, Khanna S, Bickerstaff A A, Subramanian S V, Atalay M, Bierl M, Pendyala S, Levy D, Sharma N, Venojarvi M, Strauch A, Orosz C G, Sen C K. Oxygen sensing by primary cardiac fibroblasts: a key role of p21(Waf1/Cip1/Sdi1). Circ Res 2003; 92: 264–271
  • Schafer M, Schafer C, Ewald N, Piper H M, Noll T. Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res 2003; 92: 1010–1015
  • Seko Y, Tobe K, Ueki K, Kadowaki T, Yazaki Y. Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Circ Res 1996; 78: 82–90
  • Tao Q, Spring S C, Terman B I. Comparison of the signaling mechanisms by which VEGF, H2O2, and phosphatase inhibitors activate endothelial cell ERK1/2 MAP-kinase. Microvasc Res 2005; 69: 36–44
  • Waki K, Inanami O, Yamamori T, Kuwabara M. Extracellular signal-regulated kinase 1/2 is involved in the activation of NADPH oxidase induced by FMLP receptor but not by complement receptor 3 in rat neutrophils. Free Radic Res 2003; 37: 665–671
  • Wesselman J P, Dobrian A D, Schriver S D, Prewitt R L. Src tyrosine kinases and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases mediate pressure-induced c-fos expression in cannulated rat mesenteric small arteries. Hypertension 2001; 37: 955–960
  • White C R, Stevens H Y, Haidekker M, Frangos J A. Temporal gradients in shear, but not spatial gradients, stimulate ERK1/2 activation in human endothelial cells. Am J Physiol Heart Circ Physiol 2005; 289: H2350–H2355
  • Wilson J X, Dixon S J, Yu J, Nees S, Tyml K. Ascorbate uptake by microvascular endothelial cells of rat skeletal muscle. Microcirculation 1996; 3: 211–221
  • Wu F, Tyml K, Wilson J X. Ascorbate inhibits iNOS expression in endotoxin- and IFN gamma-stimulated rat skeletal muscle endothelial cells. FEBS Lett 2002; 520: 122–126
  • Yamakoshi Y, Umezawa N, Ryu A, Arakane K, Miyata N, Goda Y, Masumizu T, Nagano T. Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2* versus 1O2. J Am Chem Soc 2003; 125: 12803–12809
  • Zhou L, Kasparek E M, Nicholson B J. Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels. J Cell Biol 1999; 144: 1033–1045

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