1
Views
1
CrossRef citations to date
0
Altmetric
Original

Afferent Arteriolar Dilation to 11, 12-EET Analogs Involves PP2A Activity and Ca2 +-Activated K+ Channels

, , , &
Pages 137-150 | Received 27 Feb 2007, Accepted 17 May 2007, Published online: 10 Jul 2009

REFERENCES

  • Archer S L, Gragasin F S, Wu X, Wang S, McMurtry S, Kim D H, Platonov M, Koshal A, Hashimoto K, Campbell W B, Falck J R, Michelakis E D. Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. Circulation 2003; 107: 769–776
  • Campbell W B, Gebremedhin D, Pratt P F, Harder D R. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 1996; 78: 15–423
  • Capdevila J H, Falck J R. The CYP P450 arachidonic acid monooxygenases: from cell signaling to blood pressure regulation. Biochem Biophys Res Commun 2001; 285: 571–576
  • Chen J K, Falck J R, Reddy K M, Capdevila J, Harris R C. Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells. J Biol Chem 1998; 273: 29254–29261
  • Cheng M K, Doumad A B, Jiang H, Falck J R, McGiff J C, Carroll M A. Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat preglomerular microvessels (PGMV) via A2A receptors. Br J Pharmacol 2004; 141: 441–448
  • Davis B B, Thompson D A, Howard L L, Morisseau C, Hammock B D, Weiss R H. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proc Natl Acad Sci USA 2002; 99: 2222–2227
  • Dimitropoulou C, Han G, Miller A W, Molero M, Fuchs L C, White R E, Carrier G O. Potassium (BK(Ca)) currents are reduced in microvascular smooth muscle cells from insulin-resistant rats. Am J Physiol Heart Circ Physiol 2002; 282: H908–917
  • Dimitropoulou C, West L, Field M B, White R E, Reddy L M, Falck J R, Imig J D. Protein phosphatase 2A and Ca(2+)-activated K(+) channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation. Prostaglandins Other Lipid Mediat 2007; 83: 50–61
  • Falck J R, Krishna U M, Reddy Y K, Kumar P S, Reddy K M, Hittner S B, Deeter C, Sharma K K, Gauthier K M, Campbell W B. Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation. Am J Physiol Heart Circ Physiol 2003; 284: H337–349
  • Falck J R, Reddy L M, Reddy Y K, Bondlela M, Krishna U M, Ji Y, Sun J, Liao J K. 11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression. Bioorg Med Chem Lett 2003; 13: 4011–4014
  • Fisslthaler B, Popp R, Kiss L, Potente M, Harder D R, Fleming I, Busse R. Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature 1999; 401: 493–497
  • Gauthier K M, Falck J R, Reddy L M, Campbell W B. 14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries. Pharmacol Res 2004; 49: 515–524
  • Gebremedhin D, Ma Y H, Falck J R, Roman R J, Van Rollins M, Harder D R. Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol 1992; 263: H519–525
  • Honkanen R E, Zwiller J, Moore R E, Daily S L, Khatra B S, Dukelow M, Boynton A L. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. J Biol Chem 1990; 265: 19401–19404
  • Imig J D. Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases. Am J Physiol Renal Physiol 2005; 289: F496–503
  • Imig J D, Falck J R, Wei S, Capdevila J H. Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin. J Vasc Res 2001; 38: 247–255
  • Imig J D, Inscho E W, Deichmann P C, Reddy K M, Falck J R. Afferent arteriolar vasodilation to the sulfonimide analog of 11, 12-epoxyeicosatrienoic acid involves protein kinase A. Hypertension 1999; 33: 408–413
  • Imig J D, Navar L G, Roman R J, Reddy K K, Falck J R. Actions of epoxygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol 1996; 7: 2364–2370
  • Imig J D, Zhao X, Capdevila J H, Morisseau C, Hammock B D. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension 2002; 39: 690–694
  • Imig J D, Zhao X, Falck J R, Wei S, Capdevila J H. Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid. J Hypertens 2001; 19: 983–992
  • Korovkina V P, England S K. Molecular diversity of vascular potassium channel isoforms. Clin Exp Pharmacol Physiol 2002; 29: 317–323
  • Krotz F, Riexinger T, Buerkle M A, Nithipatikom K, Gloe T, Sohn H Y, Campbell W B, Pohl U. Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids. Arterioscler Thromb Vasc Biol 2004; 24: 595–600
  • Kurokawa J, Motoike H K, Rao J, Kass R S. Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation. Proc Natl Acad Sci USA 2004; 101: 16374–16378
  • Ledoux J, Werner M E, Brayden J E, Nelson M T. Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) 2006; 21: 69–78
  • Li P L, Chen C L, Bortell R, Campbell W B. 11,12-Epoxyeicosatrienoic acid stimulates endogenous mono-ADP-ribosylation in bovine coronary arterial smooth muscle. Circ Res 1999; 85: 349–356
  • Li P L, Zhang D X, Ge Z D, Campbell W B. Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells. Am J Physiol Heart Circ Physiol 2002; 282: H1229–1236
  • Marx S O, Kurokawa J, Reiken S, et al. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 2002; 295: 496–499
  • McSherry I N, Sandow S L, Campbell W B, Falck J R, Hill M A, Dora K A. A role for hetrocellular coupling and EETs in dilation of rat cremaster arteries. Microcirculation 2006; 13: 119–130
  • Morin C, Sirois M, Echave V, Gomes M M, Rousseau E. EET Relaxing Effects Involve BKCa Channel Activation and CPI-17 Dephosphorylation in Human Bronchi. Am J Respir Cell Mol Biol 2007, PMID:17237191
  • Namboodiripad A N, Jennings M L. Permeability characteristics of erythrocyte membrane to okadaic acid and calyculin A. Am J Physiol 1996; 270: C449–456
  • Navar L G, Inscho E W, Majid S A, Imig J D, Harrison-Bernard L M, Mitchell K D. Paracrine regulation of the renal microcirculation. Physiol Rev 1996; 76: 425–536
  • Nishi A, Bibb J A, Matsuyama S, et al. Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A. J Neurochem 2002; 81: 832–841
  • Nishi A, Bibb J A, Snyder G L, et al. Amplification of dopaminergic signaling by a positive feedback loop. Proc Natl Acad Sci USA 2000; 97: 12840–12845
  • Node K, Ruan X L, Dai J, Yang S X, Graham L, Zeldin D C, Liao J K. Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. J Biol Chem 2001; 276: 15983–15989
  • Pallone T L, Zhang Z, Rhinehart K. Physiology of the renal medullary microcirculation. Am J Physiol Renal Physiol 2003; 284: F253–266
  • Ren Y, Garvin J L, Falck J R, Renduchintala K V, Carretero O A. Glomerular autacoids stimulated by bradykinin regulate efferent arteriole tone. Kidney Int 2003; 63: 987–993
  • Roman R J. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 2002; 82: 131–185
  • Sansom S C, Stockand J D, Hall D, Williams B. Regulation of large calcium-activated potassium channels by protein phosphatase 2A. J Biol Chem 1997; 272: 9902–9906
  • Schubert R, Nelson M T. Protein kinases: tuners of the BKCa channel in smooth muscle. Trends Pharmacol Sci 2001; 22: 505–512
  • Schweitz H, Stansfeld C E, Bidard J N, Fagni L, Maes P, Lazdunski M. Charybdotoxin blocks dendrotoxin-sensitive voltage-activated K+ channels. FEBS Lett 1989; 250: 519–522
  • Spector A A, Fang X, Snyder G D, Weintraub N L. Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. Prog Lipid Res 2004; 43: 55–90
  • Stockand J D, Silverman M, Hall D, Derr T, Kubacak B, Sansom S C. Arachidonic acid potentiates the feedback response of mesangial BKCa channels to angiotensin II. Am J Physiol 1998; 274: F658–664
  • Strong P N. Potassium channel toxins. Pharmacol Ther 1990; 46: 137–162
  • Wang D, Borrego-Conde L J, Falck J R, Sharma K K, Wilcox C S, Umans J G. Contributions of nitric oxide, EDHF, and EETs to endothelium-dependent relaxation in renal afferent arterioles. Kidney Int 2003; 63: 2187–2193
  • Wang X, Loutzenhiser R. Determinants of renal microvascular response to ACh: afferent and efferent arteriolar actions of EDHF. Am J Physiol Renal Physiol 2002; 282: F124–132
  • Wang X, Trottier G, Loutzenhiser R. Determinants of renal afferent arteriolar actions of bradykinin: evidence that multiple pathways mediate responses attributed to EDHF. Am J Physiol Renal Physiol 2003; 285: F540–549
  • White R E, Lee A B, Shcherbatko A D, Lincoln T M, Schonbrunn A, Armstrong D L. Potassium channel stimulation by natriuretic peptides through cGMP-dependent dephosphorylation. Nature 1993; 361: 263–266
  • White R E, Schonbrunn A, Armstrong D L. Somatostatin stimulates Ca(2+)-activated K+ channels through protein dephosphorylation. Nature 1991; 351: 570–573
  • Zhou X B, Ruth P, Schlossmann J, Hofmann F, Korth M. Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells. J Biol Chem 1996; 271: 19760–19767
  • Zhou X B, Schlossmann J, Hofmann F, Ruth P, Korth M. Regulation of stably expressed and native BK channels from human myometrium by cGMP- and cAMP-dependent protein kinase. Pflugers Arch 1998; 436: 725–734
  • Zou A P, Fleming J T, Falck J R, Jacobs E R, Gebremedhin D, Harder D R, Roman R J. Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. Am J Physiol 1996; 270: F822–832

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.