The mechanism of electroacupuncture for treating spinal cord injury rats by mediating Rho/Rho-associated kinase signaling pathway

References

• Gao J, Cheng LH, Min YJ. Clinical research in acupuncture treating the recovery period of SCI. Anmo yu Kangfu. 2015;6(3):18–21.
   Google Scholar
• Gao LJ, Sun YC, Li JJ, Fan B, Pengkun L. et al. Effects of electroacupuncture in different time on variations of fractional anisotropy mean value of diffusion tensor tractography in spinal cord injured rats. Chin J Rehabil Theory Prac. 2014;20:728–733.
   Google Scholar
• Min YJ, Cheng LH, Yao HH, Liu Y, Zhiyun M, Jia P. Effect of Santong electroacupuncture on expression of p75 neurotrophin receptor in rats with SCI. Chin J Rehabil Theory Pract 2017;23(6):621–627.
   Google Scholar
• Rabchevsky AG, Patel SP, Springer JE. Pharmacological interventions for SCI: where do we stand? How might we step forward?. Pharmacol Ther, Spinal Cord 2011;132:15–19.
   PubMed Web of Science ®Google Scholar
• Wang ZQMin YJ. Observation of effect on thermal moxibustion treatment of incomplete SCI urinary retention. Journal of Chengdu University of TCM 2013;36(3):60–63.
   Google Scholar
• Wang WC, Lu JC, Wang Q, et al. EFfect on the activities of daily life of the patients with traumatic SCI treated by the paraplegia-triple-needling method. Chinese Acupunctrue&Moxibustion 2012; 32(10):877–881.
   Google Scholar
• Min YJ, Cheng LH, Gao J. Comparative observations on three-unblocking acupuncture for the treatment of SCI in convalescent patients with paraplegia. Shanghai Zhenjiu Zazhi. 2013;32(10):1010–1013.
   Google Scholar
• Min ZY, Cheng LH, Min YJ. Effect of electroacupuncture on Nogo/NgR signaling pathway related factors in SCI rats. Journal of Beijing University of Traditional Chinese Medicine 2016;39(11):926–932.
   Google Scholar
• Min ZY, Cheng LH, Min YJ. REsearch progress of Nogo/NgR pathway in spinal cord nerve regeneration. Journal of Jiangxi University of TCM, 2016;28(3):103–106.
   Google Scholar
• Liu BP, Cafferty WB, Budel SO, et al. Extracellular regulators of axonal growth in the adult central nervous system. Philos Trans R Soc Lond B Biol Sci 2006;361(1473):593–610. doi: https://doi.org/10.1098/rstb.2006.1891
   PubMed Web of Science ®Google Scholar
• Bito H, Furuyashiki T, Ishihara H, Shibasaki Y, Ohashi K, Mizuno K, et al. A critical role for a RhoAssociated kinase, p160 ROCK, in determining axon outgrowth in mammalian CNS neurons. Neuron 2000;26(2):431–441. doi: https://doi.org/10.1016/S0896-6273(00)81175-7
   PubMed Web of Science ®Google Scholar
• Wu X, Walker CL, Lu Q, Wu W, Eddelman DB., Parish JM. et al. Rhoa/Rho kinase mediates neuronal death through regulating cPLA2 activation. Mol Neurobiol 2017;54(9):6885–6895. doi: https://doi.org/10.1007/s12035-016-0187-6
   PubMed Web of Science ®Google Scholar
• Monnier PP, Sierra A, Schwah Jan M, Henke-Fahle S, Mueller BK. et al. The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglyeans of the CNS glial scar. Mol Cell Neure sci, 2003;22(3):319–330. doi: https://doi.org/10.1016/S1044-7431(02)00035-0
   PubMed Web of Science ®Google Scholar
• Huang YZ, Feng DX, Li J, et al. In vitro effect of Y27632 on dorsal root ganglion neurons axonal regeneration in neogenetic rats with SCI. Chinese Journal of Spine and SpinalCord 2010;20(9):765–770.
   Google Scholar
• Kubo T, Endo M, Hata K, Taniguchi J, Kitajo K, Tomura S. et al. Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance molecule. J Neurochem 2008; 105(1):113–126. doi: https://doi.org/10.1111/j.1471-4159.2007.05125.x
   PubMed Web of Science ®Google Scholar
• Madura T, Yamashita T, Kubo T, Fujitani M, Hosokawa K, Tohyama M. Activation of Rho in the injured axons following SCI. EMBO Rep 2004; 5(4):412–417. doi: https://doi.org/10.1038/sj.embor.7400117
   PubMed Web of Science ®Google Scholar
• Elizabeth AC, Lisa AM. Mammalian phospholipases A2: mediators of inflammation, proliferation and apoptosis. Prog Lip Res 2001;40(3):167–197. doi: https://doi.org/10.1016/S0163-7827(01)00002-9
   PubMed Web of Science ®Google Scholar
• Liu NK, Zhang YP, Titsworth WL, Jiang X, Han S, Lu Pei-Hua, et al. A novel role of phospholipase A2 in mediating spinal cord secondary injury. Ann Neurol 2006;59(4):606–619. doi: https://doi.org/10.1002/ana.20798
   PubMed Web of Science ®Google Scholar
• Min YJ, Ding LLQ, Cheng LH, Xiao Wei-ping, He Xing-wei, Zhang H, et al. Effect of electroacupuncture on the mRNA and protein expression of RhoA and RhoAssociated kinase II in SCI rats. Neural Regen Res 2017;12(2):276–282. doi: https://doi.org/10.4103/1673-5374.200811
   PubMed Web of Science ®Google Scholar
• Liu NK, Deng LX, Zhang YP, Xiao-Fei W, Jian-Guo H, Eddile oaks BS, et al. Cytosolic phospholipase A2 protein as a novel therapeutic target for SCI. Ann Neurol, Spinal Cord 2014; 75(5):644–658. doi: https://doi.org/10.1002/ana.24134
   PubMed Web of Science ®Google Scholar
• Gao J, Zhang YJ, Min YJ, et al. Study and application of acupoints in the treatment of paraplegia. Jiangxi J Tradit Chin Med 2013;44(2):54–56.
   Google Scholar
• Min YJ, Deng L, Hong ES. Orthogonal study on different acupuncture factors based on hypothalamic- pituitary-adrenal axis in rats with kindey Yang deficiency. Shanghai Zhenjiu Zazhi 2016;35:339–343.
   Google Scholar
• Zhang L, Ni YQ, Li YF. Ligustrazine facilitates hair cell regeneration in the cochlea following gentamicin ototoxicity. Neural Regen Res 2010;5(10):735–740.
   Web of Science ®Google Scholar
• Chen XL, Liu L, Wen QQ, Li P, Wang Y, Wei XR, et al. Effect of acupuncture at different acupoints on RhoA/ROCK signalinging pathway in gastric antral smooth muscle tissue of rats with diabetic gastroparesis. Shijie Huaren Xiaohua Zazhi 2016;24(23):3508–3516.
   Google Scholar
• Wu XF, Chen XL, Zheng XN, Guo X, Xie ZQ, Liu L, et al. Effect of different stimulating strength of electroacupuncture on gastrointestinal motility and RhoA/ROCK signaling in gastric antral smooth muscle in diabetic gastroparesis rats. Acupuncture Research 2018;43(3):169–174.
   Google Scholar
• Shin HM, Je HD, Gallant C, Tao TC., Hartshorne DJ., Ito M, et al. Differential association and localization of myosin phosphatase subunits during agonist-induced signaling transduction in smooth muscle. Circ Res 2002;90(5):546–553. doi: https://doi.org/10.1161/01.RES.0000012822.23273.EC
   PubMed Web of Science ®Google Scholar
• Khasnis M, Nakatomi A, Gumpper K, Eto M. Reconstituted human myosin light chain phosphatase reveals distinct roles of two inhibitory phosphorylation sites of the regulatory subunit, MYPT1. Biochemistry 2014;53(16):2701–2709. doi: https://doi.org/10.1021/bi5001728
   PubMed Web of Science ®Google Scholar
• Khromov A, Choudhury N, Stevenson AS, Somlyo AV., Eto M. Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction. J Biol Chem 2009;284(32):21569–21579. doi: https://doi.org/10.1074/jbc.M109.019729
   PubMed Web of Science ®Google Scholar
• Li XN, Liang XS, Wu L, Shan XC, Fu H, Mei JL, et al. Electroacupuncture improves limb locomotor function possibly by suppressing Rho-ROCKII pathway related factors in anterior horns of spinal cord in rats with acute SCI. Acupuncture Research 2018;43(7):445–460.
   Google Scholar
• Hu HL, Huang XL, Liu F, Renfu Q, et al. Advances in experimental studies on the mechanism of huatuo jiaji (Ex-B2) point acupuncture treatment for SCI. Shanghai J Acu-mox 2016;35(12):1480–1483.
   Google Scholar
• Lü W, Yao HJ, Mo YP, et al. Nerve regeneration related signaling pathway after spinal cord injury (review). Chin J Rehabil Theory Pract 2016;22(3):293–298.
   Google Scholar