Coupling of M₃ Acetylcholine Receptor to Gq₁₆ Activates a Natriuretic Peptide Receptor Guanylyl Cyclase

REFERENCES

• Katsuki S, Murad F. Regulation of adenosine cyclic 3′,5′-monophosphate and guanosine cyclic 3′,5′-monophosphate levels and contractility in bovine tracheal smooth muscle. Mol Pharmacol 1977; 13: 330–341
   PubMed Web of Science ®Google Scholar
• Chinkers M, Garbers D L. Signal transduction by guanylyl cyclases. Annu Rev Biochem 1991; 60: 553–575
   PubMed Web of Science ®Google Scholar
• Guerra d e, Gonzalez L, Misle A, Pacheco G, Napoleon de Herrera V, Gonzalez del Alfonzo R, Lippo de Becemberg I, Alfonzo M J. Effects of 1H- [1,2,4]Oxadiazolo[4,3-]quinoxalin-1-one (ODQ) and N(6)-nitro-L-arginine methyl ester (NAME) on cyclic GMP levels during muscarinic activation of tracheal smooth muscle. Biochem Pharmacol 1999; 58: 563–569
   PubMed Web of Science ®Google Scholar
• Borges A, Sanchez de Villarroel S, Winand N J, Lippo de Becemberg I, Alfonzo M J, Gonzalez de Alfonzo R. Molecular and biochemical characterization of a G-protein-coupled B-type guanylyl cyclase in bovine airway smooth muscle. Am J Resp Cell Mol Biol 2001; 25: 98–103
   PubMed Web of Science ®Google Scholar
• Potter L R, Hunter T. Guanylyl cyclase-linked natriuretic peptide receptors: Structure and regulation. J Biol Chem 2001; 276: 6057–6060
   PubMed Web of Science ®Google Scholar
• Alfonzo M J, Peña de Aguilar E, Guevara de Murillo A, Sánchez de Villarroel S, Gonzalez de Alfonzo R, Borges A, Lippo de Becemberg I. Characterization of a G-protein coupled guanylyl cyclase-B receptor from bovine tracheal smooth muscle. J Receptor & Signal Transduction 2006; 26: 1–28
   PubMed Web of Science ®Google Scholar
• Lippo d e, Bécemberg I, Peña de Aguilar E, Camarillo I, González de Alfonzo R, Alfonzo M J. Muscarinic agents modify kinetics properties of membrane-bound guanylyl cyclase activity. FEBS Lett 1989; 253: 16–22
   PubMed Web of Science ®Google Scholar
• Lippo d e, Bécemberg I, Correa de Adjounian M, Sánchez de Villarroel S, Peña Aguilar E, González de Alfonzo R, Alfonzo M J. G-protein-sensitive guanylyl cyclase associated with plasma membranes. Arch Biochem Biophys 1995; 324: 209–215
   PubMed Web of Science ®Google Scholar
• Alfonzo M J, Lippo de Becemberg L, Sanchez de Villarroel S, Napoleon de Herrera V, Misle A J, Gonzalez de Alfonzo R. Two opposite transducing mechanisms regulate a G protein-coupled guanylyl cyclase. Arch Biochem, Biophys 1998; 350: 19–25
   PubMed Web of Science ®Google Scholar
• Misle A J, Lippo de Becemberg I., González de Alfonzo R., Alfonzo M J. Methoctramine binding sites sensitive to alkylation on muscarinic receptors from tracheal smooth muscle. Biochem Pharmacol 1994; 48: 191–195
   PubMed Web of Science ®Google Scholar
• Eglen R M, Reddy H, Watson N. Selective inactivation of muscarinic receptor subtypes. Int J Biochem 1994; 26: 1357–1368
   PubMedGoogle Scholar
• Alfonzo M J, Guerra de Gonzalez L, Sanchez de Villarroel S, Francis de Toba G, Misle A J, Napoleon de Herrera V, Gonzalez de Alfonzo R, Lippo de Becemberg I. Signal transduction pathways through mammalian guanylyl cyclases. New Advances in Cardiovascular Physiology and Pharmacology, M Velasco, R Hernandez. Excerpta Medica. 1998; 147–175
   Google Scholar
• Liu J, Conklin B R, Blin N, Yun J, Wess J. Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation. Proc Natl Acad Sci USA 1995; 92: 11642–11646
   PubMed Web of Science ®Google Scholar
• Gonzalez d e, Alfonzo R, Lippo de Becemberg I, Alfonzo M J. A Ca2 +/CaM dependent protein kinase associated with Ca2 + transport in sarco(endo) plasmic vesicles from tracheal smooth muscle. Life Sci 1996; 58: 18–24
   Web of Science ®Google Scholar
• Hilf G, Jakobs K H. Activation of solubilized G-proteins by muscarinic acetylcholine receptors. Cell Signal 1992; 4: 787–794
   PubMed Web of Science ®Google Scholar
• Woolkalis M J, Nakada M T, Manning D R. Alterations in components of adenylate cyclase associated with transformation of chicken embryo fibroblasts by Rous sarcoma virus. J Biol Chem 1986; 261: 3408–3413
   PubMed Web of Science ®Google Scholar
• Hanoune J, Stengel D, Lacombe M L. Proteolytic activation and solubilization of adenylate and guanylate cyclases. Mol Cell Endocrinol 1983; 31: 21–41
   PubMed Web of Science ®Google Scholar
• Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
   PubMed Web of Science ®Google Scholar
• Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156–159
   PubMed Web of Science ®Google Scholar
• Siebert P D, Chenchik A. Modified acid guanidinium thiocyanate-phenol-chloroform RNA extraction method which greatly reduces DNA contamination. Nucleic Acids Res 1993; 21: 2019–2020
   PubMed Web of Science ®Google Scholar
• Amy C M, Witkowski A, Naggert J, Williams B, Randhawa Z, Smith S. Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase. Proc Natl Acad Sci USA 1989; 86: 3114–3118
   PubMed Web of Science ®Google Scholar
• Wilkie T M, Aragay A M, Watson A J, Simon M I. Design of degenerate oligonucleotide primers for cloning of G-protein alpha subunits. Methods Enzymol 1994; 237: 327–344
   PubMed Web of Science ®Google Scholar
• Bensadoun A, Weinstein D. (1976) Assay of proteins in the presence of interfering materials. Anal Biochem 1976; 70: 2241–2250
   Web of Science ®Google Scholar
• Wess J. Mutational analysis of muscarinic acetylcholine receptors: Structural basis of ligand/receptor/G protein interactions. Life Sci 1993; 53: 1447–1463
   PubMed Web of Science ®Google Scholar
• Higashijima T, Burnier J, Ross E M. Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity. J Biol Chem 1990; 265: 14176–14186
   PubMed Web of Science ®Google Scholar
• Duda T, Goraczniak R, Sharma R M. Distinct inhibitory ATP-regulated modulatory domain (ARMi) in membrane guanylate cyclases. Biochem J 1996; 319: 279–283
   PubMed Web of Science ®Google Scholar
• Alfonzo M J, Sanchez de Villarroel S, Lippo de Becemberg I, Borges A, Gonzalez de Alfonzo R. Mastoparan regulates ATP inhibition of a CNP-stimulated guanylylcyclase from tracheal smooth muscle. Biophysical J 2002; 82: 218–219, (Abstract) 46th Biophysical Society Congress San Francisco, USA
   Web of Science ®Google Scholar
• Amatruda T T, III, Stelle D A, Slepak V Z, Simon M I. G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells. Proc Natl Acad Sci USA 1991; 88: 5587–5591
   PubMed Web of Science ®Google Scholar
• Maeda A, Kubo T, Mishina M, Numa S. Tissue distribution of mRNAs encoding muscarinic Acetylcholine receptor subtypes. FEBS Lett 1988; 239: 339–342
   PubMed Web of Science ®Google Scholar
• Eglen R M, Hegde S S, Watson N. Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev 1996; 48: 531–536
   PubMed Web of Science ®Google Scholar
• Nakahata N, Abe M T, Matsuoka I, Nakanishi H. Mastoparan inhibits phospho-inositide hydrolysis via pertussis toxin-insensitive G-protein in human astrocytoma cells. FEBS Lett 1990; 260: 91–94
   PubMed Web of Science ®Google Scholar
• Spalding T A, Burstein E S. Constitutive activity of muscarinic acetylcholine receptors. J Receptor & Signal Transduction 2006; 26: 61–85
   PubMed Web of Science ®Google Scholar
• Misle A J, Bruges G, Herrera V N, Alfonzo M J, Lippo de Becemberg I, Gonzalez de Alfonzo R. G-protein dependent antagonists binding in M3 mAChR from tracheal smooth muscle. Arch Venez Farmacol Terapeut 2002; 20: 144–152
   Google Scholar
• Hamm H E. The many faces of G protein signaling. J Biol Chem 1998; 278: 669–672
   Google Scholar
• Khurana M L, Pandey K N. Catalytic activation of guanylate cyclase/atrial natriuretic peptide factor receptor by combined effects of ANF and GT Pγ S in plasma membranes of Leydig tumor cells: Involvement of G-proteins. Biochim Biophys Acta 1994; 1224: 61–67
   PubMedGoogle Scholar
• Gilchrist A, Li A, Hamm H E. Design and use of C-terminal minigene vectors for studying role of heterotrimeric G proteins. Methods Enzymol 2002; 344: 58–69
   PubMed Web of Science ®Google Scholar
• Cerione R A, Kroll S, Rajaram R, Unson C, Goldsmith P, Spiegel A M. An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function. J Biol Chem 1988; 263: 9345–9352
   PubMed Web of Science ®Google Scholar
• Kusakabe Y, Yamaguchi E, Tanemura K, Kameyama K, Chiba N, Arai S, Emori Y, Abe K. Identification of two alpha-subunit species of GTP-binding proteins, Galpha15 and Galphaq, expressed in rat taste buds. Biochim Biophys Acta 1998; 1403: 265–272
   PubMed Web of Science ®Google Scholar
• Anand-Srivastava M B, Trachte G J. Atrial natriuretic factor receptors and signal transduction mechanisms. Pharmacol Rev 1993; 45: 455–497
   PubMed Web of Science ®Google Scholar
• Zhou H, Murthy K S. Identification of the G protein-activating sequence of the single transmembrane natriuretic peptide receptor C (NPR-C). Am J Physiol Cell Physiol 2003; 284: C1255–C1261
   Web of Science ®Google Scholar