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Research Article

Weak Functional Coupling of the Melanocortin-1 Receptor Expressed in Human Adipocytes

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Pages 485-504 | Published online: 19 Nov 2008

REFERENCES

  • A V Vergoni, R Poggioli, and A Bertolini. (1986). Corticotropin inhibits food intake in rats. Neuropeptides 7:153–158.
  • R D Cone. (1999). The central melanocortin system and energy homeostasis. Trends Endocrinol Metab 10:211–216.
  • R D Cone. (2006). Studies on the physiologic functions of the melanocortin system. Endocr Rev 27:736–749.
  • M W Schwartz, S C Woods, D PorteJr, R J Seeley, and D G Baskin. (2000). Central nervous system control of food intake. Nature 404:661–671.
  • J E Wikberg. (1999). Melanocortin receptors: Perspectives for novel drugs. Eur J Pharmacol 375:295–310.
  • S J Getting. (2006). Targeting melanocortin receptors as potential novel therapeutics. Pharmacol Ther 111:1–15.
  • D G Baskin. (2006). Single-minded view of melanocortin signaling in energy homeostasis. Endocrinology 147:4539–4541.
  • C K Song, R M Jackson, R B Harris, D Richard, and T J Bartness. (2005). Melanocortin-4 receptor mRNA is expressed in sympathetic nervous system outflow neurons to white adipose tissue. Am J Physiol Regul Integr Comp Physiol 289:R1467–R1476.
  • A N Eberle. The Melanotropins: Chemistry, Physiology and Mechanisms of Action. Basel, Karger, (1988).
  • B A Boston. (1999). The role of melanocortins in adipocyte function. Ann N Y Acad Sci 885:75–84.
  • A N Eberle. Proopiomelanocortin and the melanocortin peptides. In R D Cone ed.. The Melanocortin Receptors. Totowa, NJ, Humana Press (2000), 3–67.
  • B A Boston, and R D Cone. (1996). Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Endocrinology 137:2043–2050.
  • V Chhajlani. (1996). Distribution of cDNA for melanocortin receptor subtypes in human tissues. Biochem Mol Biol Int 38:73–80.
  • S R Smith, B Gawronska-Kozak, L Janderova, T Nguyen, A Murrell, J M Stephens, and R L Mynatt. (2003). Agouti expression in human adipose tissue: Functional consequences and increased expression in type 2 diabetes. Diabetes 52:2914–2922.
  • Y C Chagnon, W J Chen, L Perusse, and et al (1997). Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Quebec Family Study. Mol Med 3:663–673.
  • K Kiwaki, and J A Levine. (2003). Differential effects of adrenocorticotropic hormone on human and mouse adipose tissue. J Comp Physiol [B] 173:675–678.
  • M Hoch, A N Eberle, U Wagner, C Bussmann, T Peters, and R Peterli. (2007). Expression and localization of melanocortin-1 receptor in human adipose tissues of severely obese patients. Obesity (Silver Spring) 15:40–49.
  • O Frank, M Heim, M Jakob, A Barbero, D Schäfer, I Bendik, W Dick, M Heberer, and I Martin. (2002). Real-time quantitative RT-PCR analysis of human bone marrow stromal cells during osteogenic differentiation in vitro. J Cell Biochem 85:737–746.
  • K Gorzelniak, J Janke, S Engeli, and A M Sharma. (2001). Validation of endogenous controls for gene expression studies in human adipocytes and preadipocytes. Horm Metab Res 33:625–627.
  • A Dicker, M Kaaman, V van Harmelen, G Astrom, K L Blanc, and M Ryden. (2005). Differential function of the α 2A-adrenoceptor and phosphodiesterase-3B in human adipocytes of different origin. Int J Obes (Lond) 29:1413–1421.
  • V Chhajlani, and J E Wikberg. (1992). Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEBS Lett 309:417–420.
  • K G Mountjoy, L S Robbins, M T Mortrud, and R D Cone. (1992). The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248–1251.
  • W Siegrist, and A N Eberle. (1995). Melanocortins and their implication in melanoma. Trends Endocrinol Metab 6:115–120.
  • A Bousquet-Melou, J Galitzky, M Lafontan, and M Berlan. (1995). Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans. J Lipid Res 36:451–461.
  • J B Baumann, A N Eberle, E Christen, W Ruch, and J Girard. (1986). Steroidogenic activity of highly potent melanotropic peptides in the adrenal cortex of the rat. Acta Endocrinol (Copenh) 113:396–402.
  • S C Harmer, D J Pepper, K Cooke, H PJ Bennett, and A B Bicknell. (2008). Evidence of a possible role for Lys-γ 3-MSH in the regulation of adipocyte function. J Endocrinol 196:149–158.
  • A Catania, S Gatti, G Colombo, and J M Lipton. (2004). Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol Rev 56:1–29.
  • S K Manna, and B B Aggarwal. (1998). α -Melanocyte-stimulating hormone inhibits the nuclear transcription factor NF-κ B activation induced by various inflammatory agents. J Immunol 161:2873–2880.
  • R Bhardwaj, E Becher, K Mahnke, M Hartmeyer, T Schwarz, T Scholzen, and T A Luger. (1997). Evidence for the differential expression of the functional α -melanocyte-stimulating hormone receptor MC-1 on human monocytes. J Immunol 158:3378–3384.
  • A Catania, M Cutuli, L Garofalo, A Carlin, L Airaghi, W Barcellini, and J M Lipton. (2000). The neuropeptide α MSH in host defense. Ann N Y Acad Sci 917:227–231.
  • H Hauner. (2005). Secretory factors from human adipose tissue and their functional role. Proc Nutr Soc 64:163–169.
  • S Chung, K Lapoint, K Martinez, A Kennedy, M Boysen Sandberg, and M K McIntosh. (2006). Preadipocytes mediate LPS-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. Endocrinology 147:5340–5351.
  • K E Wellen, and G S Hotamisligil. (2003). Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 112:1785–1788.
  • S P Weisberg, D McCann, M Desai, M Rosenbaum, R L Leibel, and A W Ferrante. (2003). Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796–1808.
  • C A Curat, V Wegner, C Sengenes, M Diehl, C Tonus, R Busse, and A. Bouloumié. (2006). Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 49:744–747.
  • D B Hausman, M DiGirolamo, T J Bartness, G J Hausman, and R J Martin. (2001). The biology of white adipocyte proliferation. Obes Rev 2:239–254.
  • A Katsuki, Y Sumida, S Murashima, M Furuta, R Araki-Sasaki, K Tsuchihashi, Y Hori, Y Yano, and Y Adachi. (2000). Elevated plasma levels of α -melanocyte stimulating hormone (α -MSH) are correlated with insulin resistance in obese men. Int J Obes Relat Metab Disord. 24:1260–1264.
  • N Hoggard, A M Johnstone, P Faber, E R Gibney, M Elia, G Lobley, V Rayner, G Horgan, L Hunter, S Bashir, and R J Stubbs. (2004). Plasma concentrations of α -MSH, AgRP and leptin in lean and obese men and their relationship to differing states of energy balance perturbation. Clin Endocrinol (Oxf) 61:31–39.
  • M Böhm, T A Luger, D J Tobin, and J C Garcia-Borron. (2006). Melanocortin receptor ligands: New horizons for skin biology and clinical dermatology. J Invest Dermatol 126:1966–1975.
  • T Brzoska, T A Luger, C Maaser, C Abels, and M Böhm. (2008). α -Melanocyte-stimulating hormone and related tripeptides: Biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases. Endocr Rev 29:581–602.

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