67
Views
0
CrossRef citations to date
0
Altmetric
Meeting Review

Meeting review: a summary of the Label-Free Summit

&
Pages 128-131 | Published online: 29 Jul 2009

References

  • Rang HP. The Receptor Concept: Pharmacology’s big idea. Brit J Pharmacol (2006), 147, S9–S16.
  • Kenakin T. Principles: Receptor theory in pharmacology. Trends Pharmacol Sci (2004), 25, 186–192.
  • Lefkowitz RJ Historical review: A brief history and personal retrospective of seven-transmembrane receptors. Trends Pharmacol Sci (2004), 25, 413–422.
  • Williams C. cAMP detection methods in HTS: Selecting the best from the rest. Nature Reviews Drug Discov (2004), 3, 125–135.
  • Eglen RM. An overview of high throughput screening at G protein coupled receptors. Front Drug Des Discov (2005), 1, 97–111.
  • Thomsen W, Frazer J, Unett D. Functional assays for screening GPCR targets. Curr Opin Biotechnol (2005), 16, 655–665.
  • McLoughlin D, Bertelli F, Williams C. The A, B, Cs of G-protein-coupled receptor pharmacology in assay development for HTS. Expert Opin Drug Discov (2007), 2, 603–619.
  • Cooper MA. Current biosensor technologies in drug discovery. Drug Discov World (2006), 7, 68–81.
  • Fang Y. Label-free cell-based assays with optical biosensors in drug discovery. Assays Drug Dev Technol (2006), 4, 583–595.
  • Butcher EC, Berg EL, and Kunkel, EJ. Systems biology in drug discovery. Nature Biotechnology (2004), 22, 1253–1259.
  • Butcher EC. Can cell systems biology rescue drug discovery? Nat Rev Drug Discov (2005), 4, 461–467.
  • van der Greef J, McBurney RN. Innovation: Rescuing drug discovery: in vivo systems pathology and systems pharmacology. Nat Rev Drug Discov (2005), 4, 961–967
  • van der Greef J. Systems biology, connectivity and the future of medicine. IEEE Proc Syst Biol (2005), 4, 152 174–178.
  • Fang Y, Frutos AG, Verkelereen R. Label-free cell assays for GPCR screening. Comb Chem HTS (2008), 11, 357–369.
  • Fang Y, Ferrie AM, Fontaine NH, Yuen PK. Characteristics of dynamic mass redistribution of EGF receptor signaling in living cells measured with label free optical biosensors. Anal Chem (2005), 77, 5720–5725.
  • Fang Y, Li G, Peng J. Optical biosensor provides insights for bradykinin B2 receptor signaling in A431 cells. FEBS Lett (2005), 579, 6365–6374.
  • Treherne, JM. Exploiting high-throughput ion channel screening technologies in integrated drug discovery. Curr Pharm Des (2006), 12, 397–406.
  • Mayr LM, Fuerst P. The future of high-throughput screening. J Biomol Screen (2008), 13, 443–448.
  • Fang Y, Ferrie AM, Fontaine NH, Mauro J, Balakrishnan J. Resonant waveguide grating biosensor for living cell sensing. Biophys J (2006), 91, 1925–1940.
  • Fang Y, Li G, Ferrie AM. Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells. J Pharmacol Toxicol Methods (2007), 55, 314–322.
  • Fang Y, Ferrie AM. Label-free optical biosensor for ligand-directed functional selectivity of acting on β2 adrenoceptor in living cells. FEBS Lett (2008), 582, 558–564.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.