242
Views
16
CrossRef citations to date
0
Altmetric
Research Article

miR-128 promoted adipogenic differentiation and inhibited osteogenic differentiation of human mesenchymal stem cells by suppression of VEGF pathway

, , &
Pages 217-223 | Received 25 Feb 2016, Accepted 24 Jun 2016, Published online: 02 Aug 2016

References

  • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281–97.
  • Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006;6:259–69.
  • Mendell JT. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle 2005;4:1179–84.
  • Aranha MM, Santos DM, Sola S, et al. miR-34a regulates mouse neural stem cell differentiation. PLoS One 2011;6:e21396.
  • Kloosterman WP, Plasterk RH. The diverse functions of microRNAs in animal development and disease. Dev Cell 2006;11:441–50.
  • Bernstein E, Kim SY, Carmell MA, et al. Dicer is essential for mouse development. Nat Genet 2003;35:215–17.
  • Murchison EP, Partridge JF, Tam OH, et al. Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A 2005;102:12135–40.
  • Cao Y, LV Q, LV C. MicroRNA-153 suppresses the osteogenic differentiation of human mesenchymal stem cells by targeting bone morphogenetic protein receptor type II. Int J Mol Med 2015;36:760–6.
  • Huang K, Fu J, Zhou W, et al. MicroRNA-125b regulates osteogenic differentiation of mesenchymal stem cells by targeting Cbfβ in vitro. Biochimie 2014;102:47–55.
  • Qu J, Lu D, Guo H, et al. MicroRNA-9 regulates osteoblast differentiation and angiogenesis via the AMPK signaling pathway. Mol Cell Biochem 2016;411:23–33.
  • Meng YB, Li X, Li ZY, et al. microRNA-21 promotes osteogenic differentiation of mesenchymal stem cells by the PI3K/β-catenin pathway. J Orthop Res 2015;33:957–64.
  • Zhang L, Li K, Yan X, et al. MicroRNA-498 inhibition enhances the differentiation of human adipose-derived mesenchymal stem cells into podocyte-like cells. Stem Cells Dev 2016;411:23–33.
  • Zhao XL, Yang B, Ma LN, Dong YH. MicroRNA-1 effectively induces differentiation of myocardial cells from mouse bone marrow mesenchymal stem cells. Artif Cells Nanomed Biotechnol 2016. [Epub ahead of print]. doi: 10.3109/21691401.2015.1080168.
  • Zhang GY, Wang J, Jia YJ, et al. MicroRNA-9 promotes the neuronal differentiation of rat bone marrow mesenchymal stem cells by activating autophagy. Neural Regen Res 2015;10:314–20.
  • Pignolo RJ, Ramaswamy G, Fong JT, et al. Progressive osseous heteroplasia: diagnosis, treatment, and prognosis. Appl Clin Genet 2015;8:37–48.
  • Tan J, Xu X, Tong Z, et al. Decreased osteogenesis of adult mesenchymal stem cells by reactive oxygen species under cyclic stretch: a possible mechanism of age related osteoporosis. Bone Res 2015;3:15003.
  • Huang J, Zhao L, Xing L, Chen D. MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 2010;28:357–64.
  • Zhang JF, Fu WM, He ML, et al. MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting osterix. Mol Biol Cell 2011;22:3955–61.
  • Wang J, Guan X, Guo F, et al. miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6. Cell Death Dis 2013;4:e845.
  • Jeong BC, Kang IH, Hwang YC, et al. MicroRNA-194 reciprocally stimulates osteogenesis and inhibits adipogenesis via regulating COUP-TFII expression. Cell Death Dis 2014;5:e1532.
  • Ciafre SA, Galardi S, Mangiola A, et al. Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 2005;334:1351–8.
  • Zhang Y, Chao T, Li R, et al. MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med (Berl) 2009;87:43–51.
  • Bruno IG, Karam R, Huang L, et al. Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell 2011;42:500–10.
  • Lin Q, Wei W, Coelho CM, et al. The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nat Neurosci 2011;14:1115–17.
  • Evangelisti C, Florian MC, Massimi I, et al. MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. FASEB J 2009;23:4276–87.
  • Dong X, Tang S, Zhang W, et al. GPR39 activates proliferation and differentiation of porcine intramuscular preadipocytes through targeting the PI3K/AKT cell signaling pathway. J Recept Signal Transduct Res 2016;36:130–8.
  • Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 2010;11:597–610.
  • Siomi H, Siomi MC. Posttranscriptional regulation of microRNA biogenesis in animals. Mol Cell 2010;38:323–32.
  • Shivdasani RA. MicroRNAs: regulators of gene expression and cell differentiation. Blood 2006;108:3646–53.
  • Selvarajan S, Lund LR, Takeuchi T, et al. A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation. Nat Cell Biol 2001;3:267–75.
  • Camp HS, Ren D, Leff T. Adipogenesis and fat-cell function in obesity and diabetes. Trends Mol Med 2002;8:442–7.
  • Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006;7:885–96.
  • Shi C, Zhang M, Tong M, et al. miR-148a is associated with obesity and modulates adipocyte differentiation of mesenchymal stem cells through Wnt signaling. Sci Rep 2015;5:9930.
  • Oliverio M, Schmidt E, Mauer J, et al. Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function. Nat Cell Biol 2016;18:328–36.
  • Price NL, Holtrup B, Kwei SL, et al. SREBP-1c/MicroRNA 33b genomic loci control adipocyte differentiation. Mol Cell Biol 2016;36:1180–93.
  • Mi W, Shi Q, Chen X, et al. miR-33a-5p modulates TNF-α-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs. FEBS Lett 2016;590:396–407.
  • Yang L, Ge D, Cao X, et al. MiR-214 attenuates osteogenic differentiation of mesenchymal stem cells via targeting FGFR1. Cell Physiol Biochem 2016;38:809–20.
  • Yan J, Guo D, Yang S, et al. Inhibition of miR-222-3p activity promoted osteogenic differentiation of hBMSCs by regulating Smad5-RUNX2 signal axis. Biochem Biophys Res Commun 2016;470:498–503.
  • Nicoli S, Standley C, Walker P, et al. MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis. Nature 2010;464:1196–200.
  • Yue X, Wang P, Xu J, et al. MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A. Oncol Rep 2012;27:1200–6.
  • Liu F, Lou YL, Wu J, et al. Upregulation of microRNA-210 regulates renal angiogenesis mediated by activation of VEGF signaling pathway under ischemia/perfusion injury in vivo and in vitro. Kidney Blood Press Res 2012;35:182–91.
  • Zhang K, Zhang C, Liu L, Zhou J. A key role of microRNA-29b in suppression of osteosarcoma cell proliferation and migration via modulation of VEGF. Int J Clin Exp Pathol 2014;7:5701–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.