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Research Article

Exploring disorder in the human charged biased proteins

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Pages 386-390 | Received 07 Oct 2016, Accepted 13 Jan 2017, Published online: 14 Feb 2017

References

  • Dunker AK, Brown CJ, Lawson JD, et al. Intrinsic disorder and protein function. Biochemistry 2002;41:6573–82.
  • Xue B, Dunker AK, Uversky VN. Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life. J Biomol Struct Dyn 2012;30:137–49.
  • Uversky VN, Dunker AK. Understanding protein non-folding. Biochim Biophys Acta 2010;1804:1231–64.
  • Tompa P. Unstructural biology coming of age. Curr Opin Struct Biol 2011;21:419–25.
  • Pietrosemoli N, García-Martín JA, Solano R, Pazos F. Genome-wide analysis of protein disorder in Arabidopsis thaliana: implications for plant environmental adaptation. PLoS One 2013;8:e55524.
  • Uversky VN. Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders. Front Aging Neurosci 2015;7:18.
  • Uversky VN, Oldfield CJ, Dunker AK. Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling. J Mol Recognit 2005;18:343–84.
  • Dosztányi Z, Chen J, Dunker AK, et al. Disorder and sequence repeats in hub proteins and their implications for network evolution. J Proteome Res 2006;5:2985–95.
  • Das S, Pal U, Das S, et al. Sequence complexity of amyloidogenic regions in intrinsically disordered human proteins. PLoS One 2014;9:e89781.
  • Choura M, Rebaï A. Exploring charged biased regions in the human proteome. Gene 2013;515:277–80.
  • Kriventseva EV, Tegenfeldt F, Petty TJ, et al. OrthoDB v8: update of the hierarchical catalog of orthologs and the underlying free software. Nucleic Acids Res 2015;43:D250–6.
  • Dosztányi Z, Csizmok V, Tompa P, Simon I. IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 2005;21:3433–4.
  • Dosztányi Z, Mészáros B, Simon I. ANCHOR: web server for predicting protein binding regions in disordered proteins. Bioinformatics 2009;25:2745–6.
  • Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009;4:44–57.
  • Szklarczyk D, Franceschini A, Wyder S, et al. STRING v10: protein–protein interaction networks, integrated over the tree of life. Nucleic Acids Res 2015;43:D447–52.
  • Campen A, Williams RM, Brown CJ, et al. TOP-IDP-scale: a new amino acid scale measuring propensity for intrinsic disorder. Protein Pept Lett 2008;15:956–63.
  • Williams DC, Cai M, Clore GM. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J Biol Chem 2004;279:1449–57.
  • Guo X, Bulyk ML, Hartemink AJ. Intrinsic disorder within and flanking the DNA-binding domains of human transcription factors. Pac Symp Biocomput 2012;104–15.
  • Vuzman D, Levy Y. Intrinsically disordered regions as affinity tuners in protein–DNA interactions. Mol Biosyst 2012;8:47–57.
  • Fong JH, Panchenko AR. Intrinsic disorder and protein multibinding in domain, terminal, and linker regions. Mol Biosyst 2010;6:1821–8.
  • Moesa HA, Wakabayashi S, Nakai K, Patil A. Chemical composition is maintained in poorly conserved intrinsically disordered regions and suggests a means for their classification. Mol Biosyst 2012;8:3262–73.
  • Sievers F, Wilm A, Dineen DG, et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol 2011;7:539.

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