The effects of all-trans retinoic acid on estrogen receptor signaling in the estrogen-sensitive MCF/BUS subline

References

• Conzen SD. Minireview: nuclear receptors and breast cancer. Mol Endocrinol. 2008;22:2215–2228.
   PubMedGoogle Scholar
• Fitzgerald P, Teng M, Chandraratna RA, et al. Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. Cancer Res. 1997;57:2642–2650.
   PubMed Web of Science ®Google Scholar
• Garattini E, Bolis M, Garattini SK, et al. Retinoids and breast cancer: from basic studies to the clinic and back again. Cancer Treat Rev. 2014;40:739–749.
   PubMed Web of Science ®Google Scholar
• di Masi A, Leboffe L, De Marinis E, et al. Retinoic acid receptors: from molecular mechanisms to cancer therapy. Mol Aspects Med. 2015;41:1–115.
   PubMed Web of Science ®Google Scholar
• Liu Y, Lee MO, Wang HG, et al. Retinoic acid receptor beta mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol. 1996;16:1138–1149.
   PubMed Web of Science ®Google Scholar
• Centritto F, Paroni G, Bolis M, et al. Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: luminal phenotype and RARα expression. EMBO Mol Med. 2015;7:950–972.
   PubMed Web of Science ®Google Scholar
• Bolis M, Garattini E, Paroni G, et al. Network-guided modeling allows tumor-type independent prediction of sensitivity to all-trans-retinoic acid. Ann Oncol. 2017;28:611–621.
   PubMed Web of Science ®Google Scholar
• Gottardis MM, Lamph WW, Shalinsky DR, et al. The efficacy of 9-cis retinoic acid in experimental models of cancer. Breast Cancer Res Treatment. 1996;38:85–96.
   PubMed Web of Science ®Google Scholar
• Ross-Innes CS, Stark R, Holmes K. a, et al. Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer. Genes Dev. 2010;24:171–182.
   PubMed Web of Science ®Google Scholar
• Lee SK, Choi HS, Song MR, et al. Estrogen receptor, a common interaction partner for a subset of nuclear receptors. Mol Endocrinol. 1998;12:1184–1192.
   PubMed Web of Science ®Google Scholar
• Pratt MAC, Deonarine D, Teixeira C, et al. The AF-2 region of the retinoic acid receptor α mediates retinoic acid inhibition of estrogen receptor function in breast cancer cells. J Biol Chem. 1996;271:20346–20352.
   PubMed Web of Science ®Google Scholar
• Hua S, Kittler R, White KP. A genomic mechanism for antagonism between retinoic acid and estrogen signaling in breast cancer. Cell. 2009;137:1259–1271.
   PubMed Web of Science ®Google Scholar
• Butler WB, Fontana JA. Responses to retinoic acid of tamoxifen-sensitive and -resistant sublines of human breast cancer cell line MCF-7. Cancer Res. 1992;52:6164LP–6167.
   Web of Science ®Google Scholar
• Coser KR, Wittner BS, Rosenthal NF, et al. Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor. Proc Natl Acad Sci USA. 2009;106:14536–14541.
   PubMed Web of Science ®Google Scholar
• Rasmussen TH, Nielsen JB. Critical parameters in the MCF-7 cell proliferation bioassay (E-Screen). Biomarkers. 2002;7:322–336.
   PubMed Web of Science ®Google Scholar
• Houtman R, de Leeuw R, Rondaij M, et al. Serine-305 phosphorylation modulates estrogen receptor alpha binding to a coregulator peptide array, with potential application in predicting responses to tamoxifen. Mol Cancer Ther. 2012;11:805–816.
   PubMed Web of Science ®Google Scholar
• Demirpence E, Demirpence E, Balaguer P, et al. Antiestrogenic effects of all-trans-retinoic acid and 1,25-dihydroxyvitamin D 3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms. Cancer Res. 1994;54:1458–1464.
   PubMed Web of Science ®Google Scholar
• Klinge CM, Bodenner DL, Desai D, et al. Binding of type II nuclear receptors and estrogen receptor to full and half-site estrogen response elements in vitro. Nucleic Acids Res. 1997;25:1903–1912.
   PubMed Web of Science ®Google Scholar
• Dahlman-Wright K, Qiao Y, Jonsson P, et al. Interplay between AP-1 and estrogen receptor α in regulating gene expression and proliferation networks in breast cancer cells. Carcinogenesis. 2012;33:1684–1691.
   PubMed Web of Science ®Google Scholar
• Amiry N, Kong X, Muniraj N, et al. Trefoil factor-1 (TFF1) enhances oncogenicity of mammary carcinoma cells. Endocrinology. 2009;150:4473–4483.
   PubMed Web of Science ®Google Scholar
• Dedieu S, Lefebvre P. Retinoids interfere with the AP1 signalling pathway in human breast cancer cells. Cell Signal. 2006;18:889–898.
   PubMed Web of Science ®Google Scholar
• Wang S, Houtman R, Melchers D, et al. A 155-plex high-throughput in vitro coregulator binding assay for (anti-)estrogenicity testing evaluated with 23 reference compounds. ALTEX. 2013;30:145–157.
   PubMedGoogle Scholar
• Aarts JMMJG, Wang S, Houtman R, et al. Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure. Chem Res Toxicol. 2013;26:336–346.
   PubMed Web of Science ®Google Scholar
• Miro Estruch I, Melchers D, Houtman R, et al. Characterization of the differential coregulator binding signatures of the retinoic acid receptor subtypes upon (ant)agonist action. Biochim Biophys Acta – Proteins Proteomics. 2017;1865:1195–1206.
   Web of Science ®Google Scholar
• Salazar MD, Ratnam M, Patki M, et al. During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein. Breast Cancer Res. 2011;13:R18.
   PubMed Web of Science ®Google Scholar
• De Barros Rossetto D, Nishimura Kiyomoto E, Brantis de Carvalho CE, et al. New ligands of the cellular retinoic acid-binding protein 2 (CRABP2) suggest a role for this protein in chromatin remodeling. Rev Ciênc Farm Básica Apl. 2014;35:371–377.
   Google Scholar
• Germain P, Gaudon C, Pogenberg V, et al. Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists. Chem Biol. 2009;16:479–489.
   PubMed Web of Science ®Google Scholar
• Olsen CM, Meussen-Elholm ETM, Samuelsen M, et al. Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4′-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human. Pharmacol Toxicol. 2003;92:180–188.
   PubMedGoogle Scholar
• Raam S, Richardson GS, Bradley F, et al. Translocation of cytoplasmic estrogen receptors to the nucleus: immunohistochemical demonstration utilizing rabbit antibodies to estrogen receptors of mammary carcinomas. Breast Cancer Res Treat. 1983;3:179–199.
   Google Scholar
• Han Y-H, Zhou H, Kim J-H, et al. A unique cytoplasmic localization of retinoic acid receptor-gamma and its regulations. J Biol Chem. 2009;284:18503–18514.
   PubMed Web of Science ®Google Scholar
• Piskunov A, Rochette-Egly C. A retinoic acid receptor RAR[alpha] pool present in membrane lipid rafts forms complexes with G protein [alpha]Q to activate p38MAPK. Oncogene. 2012;31:3333–3345.
   PubMed Web of Science ®Google Scholar
• Nonclercq D, Journé F, Laïos I, et al. Effect of nuclear export inhibition on estrogen receptor regulation in breast cancer cells. J Mol Endocrinol. 2007;39:105–118.
   PubMed Web of Science ®Google Scholar
• Marino M, Galluzzo P, Ascenzi P. Estrogen signaling multiple pathways to impact gene transcription. CG. 2006;7:497–508.
   Google Scholar
• Lu Q, Ebling H, Mittler J, et al. MAP kinase mediates growth factor-induced nuclear translocation of estrogen receptor α. FEBS Lett. 2002;516:1–8.
   PubMed Web of Science ®Google Scholar