Functional role of miR-148a in oropharyngeal cancer: influence on pregnane X receptor and P-glycoprotein expression

References

• Gupta B, Johnson NW, Kumar N. Global epidemiology of head and neck cancers: a continuing challenge. Oncology. 2016;91(1):13–23.
   PubMed Web of Science ®Google Scholar
• Fanucchi M, Khuri FR. Chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck. Semin Oncol. 2004;31(6):809–815.
   PubMed Web of Science ®Google Scholar
• Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics. 2008;9(1):105–127.
   PubMed Web of Science ®Google Scholar
• Theile D, Ketabi-Kiyanvash N, Herold-Mende C, et al. Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma. Head Neck. 2011;33(7):959–968.
   PubMed Web of Science ®Google Scholar
• Guengerich FP. Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu Rev Pharmacol Toxicol. 1999;39(1):1–17.
   PubMed Web of Science ®Google Scholar
• Bertilsson G, Heidrich J, Svensson K, et al. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc Natl Acad Sci USA. 1998;95(21):12208–12213.
   PubMed Web of Science ®Google Scholar
• Harmsen S, Meijerman I, Beijnen JH, et al. Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2009;64(1):35–43.
   PubMed Web of Science ®Google Scholar
• Synold TW, Dussault I, Forman BM. The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med. 2001;7(5):584–590.
   PubMed Web of Science ®Google Scholar
• Pondugula SR, Mani S. Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response. Cancer Lett. 2013;328(1):1–9.
   PubMed Web of Science ®Google Scholar
• Rigalli JP, Reichel M, Reuter T, et al. The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma. PLoS One. 2018;13(2):e0193242.
   PubMed Web of Science ®Google Scholar
• Rigalli JP, Reuter T, Herold-Mende C, et al. Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro. Cancer Chemother Pharmacol. 2013;71(5):1335–1343.
   PubMed Web of Science ®Google Scholar
• Betel D, Koppal A, Agius P, et al. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol. 2010;11(8):R90.
   PubMed Web of Science ®Google Scholar
• Takagi S, Nakajima M, Mohri T, et al. Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4. J Biol Chem. 2008; 283(15):9674–9680.
   PubMed Web of Science ®Google Scholar
• Li Y, Deng X, Zeng X, et al. The Role of Mir-148a in Cancer. J Cancer. 2016; 7(10):1233–4112.
   PubMed Web of Science ®Google Scholar
• Takahashi M, Cuatrecasas M, Balaguer F, et al. The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One. 2012;7(10):e46684.
   PubMed Web of Science ®Google Scholar
• Lombard AP, Mooso BA, Libertini SJ, et al. miR-148a dependent apoptosis of bladder cancer cells is mediated in part by the epigenetic modifier DNMT1. Mol Carcinog. 2016; 55(5):757–767.
   PubMed Web of Science ®Google Scholar
• Hummel R, Watson DI, Smith C, et al. Mir-148a improves response to chemotherapy in sensitive and resistant oesophageal adenocarcinoma and squamous cell carcinoma cells. J Gastrointest Surg. 2011;15(3):429–438.
   PubMed Web of Science ®Google Scholar
• Nahand JS, Taghizadeh-Boroujeni S, Karimzadeh M, et al. microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer. J Cell Physiol. 2019;234(10):17064–17099.
   PubMed Web of Science ®Google Scholar
• Bahrami A, Aledavood A, Anvari K, et al. The prognostic and therapeutic application of microRNAs in breast cancer: Tissue and circulating microRNAs. J Cell Physiol. 2018;233(2):774–786.
   PubMed Web of Science ®Google Scholar
• Ninck S, Reisser D, Dyckhoff G, et al. Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck. Int J Cancer. 2003;106(1):34–44.
   PubMed Web of Science ®Google Scholar
• König SK, Herzog M, Theile D, et al. Impact of drug transporters for the cellular resistance towards saquinavir and darunavir. J. Antimicrob Chemother. 2010;65(11):2319–2328.
   PubMed Web of Science ®Google Scholar
• Swart M, Dandara C. Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance. Front Genet. 2014;5:167.
   PubMed Web of Science ®Google Scholar
• Reuter T, Warta R, Theile D, et al. Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma. Naunyn-Schmiedeberg's Arch Pharmacol. 2015;388(11):1141–1150.
   Google Scholar
• Kliewer SA, Moore JT, Wade L, et al. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell. 1998;92(1):73–82.
   PubMed Web of Science ®Google Scholar
• Yue X, Akahira J, Utsunomiya H, et al. Steroid and Xenobiotic Receptor (SXR) as a possible prognostic marker in epithelial ovarian cancer. Pathol Int. 2010;60(5):400–406.
   PubMed Web of Science ®Google Scholar
• Rioja J, Bandres E, Rosell Costa D, et al. Association of steroid and xenobiotic receptor (SXR) and multidrug resistance 1 (MDR1) gene expression with survival among patients with invasive bladder carcinoma. BJU Int. 2011;107(11):1833–1838.
   PubMed Web of Science ®Google Scholar
• Masuyama H, Hiramatsu Y, Kodama J, et al. Expression and potential roles of pregnane X receptor in endometrial cancer. J Clin Endocrinol Metab. 2003;88(9):4446–4454.
   PubMed Web of Science ®Google Scholar
• Conde I, Lobo MV, Zamora J, et al. Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha. BMC Cancer. 2008;8(1):174.
   PubMedGoogle Scholar
• Pondugula SR, Brimer-Cline C, Wu J, et al. A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor. Drug Metab Dispos. 2009;37(4):719–730.
   PubMed Web of Science ®Google Scholar
• Wang H, Venkatesh M, Li H, et al. Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice. J Clin Invest. 2011;121(8):3220–3232.
   PubMed Web of Science ®Google Scholar
• Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science. 2004;304(5670):594–596.
   PubMed Web of Science ®Google Scholar
• Sharma D, Turkistani AA, Chang W, et al. Negative regulation of human Pregnane X receptor by microRNA-18a-5p: evidence for suppression of microRNA-18a-5p Expression by Rifampin and Rilpivirine. Mol Pharmacol. 2017;92(1):48–56.
   PubMed Web of Science ®Google Scholar
• Shuang Y, Li C, Zhou X, et al. Expression of miR-195 in laryngeal squamous cell carcinoma and its effect on proliferation and apoptosis of Hep-2. Eur Rev Med Pharmacol Sci. 2017;21(14):3232–3238.
   PubMed Web of Science ®Google Scholar
• Moratin J, Hartmann S, Brands R, et al. Evaluation of miRNA-expression and clinical tumour parameters in oral squamous cell carcinoma (OSCC). J Craniomaxillofac Surg. 2016;44(7):876–881.
   PubMed Web of Science ®Google Scholar
• Maiti M, Nauwelaerts K, Herdewijn P. Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing. Bioorg Med Chem Lett. 2012;22(4):1709–1711.
   PubMed Web of Science ®Google Scholar
• Agarwal V, Bell GW, Nam JW, et al. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 2015;12:4.
   Google Scholar
• Wong N, Wang X. miRDB: an online resource for microRNA target prediction and functional annotations. Nucleic Acids Res. 2015;43(D1):D146–D152.
   PubMed Web of Science ®Google Scholar
• Breier A, Stetka J, Bohacova V, et al. Effect of 9-cis retinoic acid and all-trans retinoic acid in combination with verapamil on P-glycoprotein expression in L1210 cells. Neoplasma. 2014;61(5):553–565.
   PubMed Web of Science ®Google Scholar
• Geick A, Eichelbaum M, Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem. 2001;276(18):14581–14587.
   PubMed Web of Science ®Google Scholar
• Rigalli JP, Tocchetti GN, Weiss J. Modulation of ABC transporters by nuclear receptors. Physiological, pathological and pharmacological aspects. CMC. 2019;26(7):1079–1112.
   PubMed Web of Science ®Google Scholar
• Chen MJ, Cheng YM, Chen CC, et al. MiR-148a and miR-152 reduce tamoxifen resistance in ER + breast cancer via downregulating ALCAM. Biochem Biophys Res Commun. 2017;483(2):840–846.
   PubMed Web of Science ®Google Scholar