Modulations in the ATPases during ketamine-induced schizophrenia and regulatory effect of “3-(3, 4-dimethoxy phenyl) -1- (4-methoxyphenyl) prop-2-en-1-one”: an in vivo and in silico studies

References

• Kapur S, Remington G. Dopamine D2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient. Biol Psychiatry. 2001;50(11):873–883.
   PubMed Web of Science ®Google Scholar
• Kim JS, Kornhuber HH, Schmid-Burgk W, et al. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Lett. 1980;20(3):379–382.
   PubMed Web of Science ®Google Scholar
• Carlsson A, Waters N, Holm-Waters S, et al. Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence. Annu Rev Pharmacol Toxicol. 2001;41(1):237–260.
   PubMedGoogle Scholar
• Shao L, Martin MV, Watson SJ, et al. Mitochondrial involvement in psychiatric disorders. Ann Med. 2008;40(4):281–295.
   PubMed Web of Science ®Google Scholar
• Clay HB, Sillivan S, Konradi C. Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia. Int J Dev Neurosci. 2011;29(3):311–324.
   PubMed Web of Science ®Google Scholar
• Dror N, Klein E, Karry R, et al. State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia. Mol Psychiatry. 2002;7(9):995–1001.
   PubMed Web of Science ®Google Scholar
• Volz HP, Riehemann S, Maurer I, et al. Reduced phosphodiesters and high-energy phosphates in the frontal lobe of schizophrenic patients: a 31P chemical shift spectroscopic-imaging study. Biol Psychiatry. 2000;47(11):954–961.
   PubMed Web of Science ®Google Scholar
• Courtney RS, O’Donovan S, McCullumsmith RE, et al. Defects in bioenergetic coupling in schizophrenia. Biol Psychiatry. 2018;83(9):739–750.
   PubMed Web of Science ®Google Scholar
• Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001;21(10):1133–1145.
   PubMed Web of Science ®Google Scholar
• Allison DB, Mentore JL, Heo M, et al. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry. 1999;156(11):1686–1696.
   PubMed Web of Science ®Google Scholar
• Meyer JM. A retrospective comparison of lipid, glucose, and weight changes at one year between olanzapine and risperidone treated inpatients. Biol Psychiat. 2001;49(8):536.
   Web of Science ®Google Scholar
• Coulter DM, Bate A, Meyboom RHB, et al. Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study. BMJ. 2001;322(7296):1207–1209.
   PubMed Web of Science ®Google Scholar
• Chintha V, Wudayagiri R. Bioavailability and Neuroprotectivity of 3-(3, 4-dimethoxy phenyl)-1-4 (methoxy phenyl) prop-2-en-1-one against Schizophrenia: an in silico approach. J Recept Signal Transduct Res. 2019;39(5–6):392–398.
   PubMed Web of Science ®Google Scholar
• Fraga DB, Réus GZ, Abelaira HM, et al. Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration. Rev Bras Psiquiatr. 2013;35(3):262–266.
   PubMed Web of Science ®Google Scholar
• Li N, Wu X, Li L. Chronic administration of clozapine alleviates reversal-learning impairment in isolation-reared rats. Behav Pharmacol. 2007;18(2):135–145.
   PubMed Web of Science ®Google Scholar
• Fritz PJ, Hamrick ME. Enzymatic analysis of adenosinetriphosphatase. Enzymologia. 1966;30(1):57–64.
   PubMedGoogle Scholar
• Desaiah D, Ho IK. Effects of acute and continuous morphine administration on catecholamine-sensitive adenosine triphosphatase in mouse brain. J Pharmacol Exp Ther. 1979;208(1):80–85.
   PubMed Web of Science ®Google Scholar
• Lowry OH, Lopez JA. The determination of inorganic phosphate in the presence of labile phosphate esters. J Biol Chem. 1946;162:421–428.
   PubMed Web of Science ®Google Scholar
• Phillips TD, Hayes AW. Effects of patulin on adenosine triphosphatase activities in the mouse. Toxicol Appl Pharmacol. 1977;42(1):175–187.
   PubMed Web of Science ®Google Scholar
• Mcllwain H. 1963. Chemical exploration of the brain: a study of cerebral excitability and ion movement (Vol. 33). Amsterdam: Elsevier Pub. Co.
   Google Scholar
• Sastry GM, Adzhigirey M, Day T, et al. Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments. J Comput Aided Mol Des. 2013;27(3):221–234.
   PubMed Web of Science ®Google Scholar
• Singh T, Biswas D, Jayaram B. AADS-An automated active site identification, docking, and scoring protocol for protein targets based on physicochemical descriptors. J Chem Inf Model. 2011;51(10):2515–2527.
   PubMed Web of Science ®Google Scholar
• Morris GM, Huey R, Lindstrom W, et al. AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility. J Comput Chem. 2009;30(16):2785–2791.
   PubMed Web of Science ®Google Scholar
• Vilar S, Cozza G, Moro S. Medicinal chemistry and the molecular operating environment (MOE): application of QSAR and molecular docking to drug discovery. CTMC. 2008;8(18):1555–1572.
   Google Scholar
• Kodama TAKAO. Thermodynamic analysis of muscle ATPase mechanisms. Physiol Rev. 1985;65(2):467–551.
   PubMed Web of Science ®Google Scholar
• Gendron FP, Krugh OBB, Kong Q, et al. Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition. CDT. 2002;3(3):229–245.
   Google Scholar
• Wyse AT, Streck EL, Worm P, et al. Preconditioning prevents the inhibition of Na+/K+-ATPase activity after brain ischemia. Neurochem Res. 2000;25(7):971–975.
   PubMed Web of Science ®Google Scholar
• Kurup ARK, Kurup PA. Membrane Na+/K+-ATPase mediated cascade in bipolar mood disorder, major depressive disorder, and schizophrenia relationship to hemispheric dominance. Int J Neurosci. 2002;112(8):965–982.
   PubMed Web of Science ®Google Scholar
• Aperia A. New roles for an old enzyme: Na, K-ATPase emerges as an interesting drug target. J Intern Med. 2007;261(1):44–52.
   PubMed Web of Science ®Google Scholar
• Lees GJ. Inhibition of sodium-potassium-ATPase: a potentially ubiquitous mechanism contributing to central nervous system neuropathology. Brain Res Rev. 1991;16(3):283–300.
   PubMedGoogle Scholar
• Brines ML, Tabuteau H, Sundaresan S, et al. Regional distributions of hippocampal Na+, K+ -ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy. Epilepsia. 1995;36(4):371–383.
   PubMed Web of Science ®Google Scholar
• Banerjee U, Dasgupta A, Rout JK, et al. Effects of lithium therapy on Na+/K+-ATPase activity and lipid peroxidation in bipolar disorder. Prog Neuro-Psychopharmacol Biol Psychiatry. 2012;37(1):56–61.
   PubMed Web of Science ®Google Scholar
• Renkawek K, Renier WO, Pont JHHM, et al. Neonatal status convulsivus, spongiform encephalopathy, and low activity of Na+/K+-ATPase in the brain. Epilepsia. 1992;33(1):58–64.
   PubMed Web of Science ®Google Scholar
• Rose AM, Valdes R. Understanding the sodium pump and its relevance to disease. Clin Chem. 1994;40(9):1674–1685.
   PubMed Web of Science ®Google Scholar
• Brines ML, Robbins RJ. Inhibition of α2/α3 sodium pump isoforms potentiates glutamate neurotoxicity. Brain Res. 1992;591(1):94–102.
   PubMed Web of Science ®Google Scholar
• Zhang D, Hou Q, Wang M, et al. Na, K-ATPase activity regulates AMPA receptor turnover through proteasome-mediated proteolysis. J Neurosci. 2009;29(14):4498–4511.
   PubMed Web of Science ®Google Scholar
• Vegh MJ, de Waard MC, van der Pluijm I, et al. Synaptic proteome changes in a DNA repair deficient ercc1 mouse model of accelerated aging. J Proteome Res. 2012;11(3):1855–1867.
   PubMed Web of Science ®Google Scholar
• Takser L, Mergler D, Hellier G, et al. Manganese, monoamine metabolite levels at birth, and child psychomotor development. Neurotoxicology. 2003;24(4–5):667–674.
   PubMed Web of Science ®Google Scholar
• Hohmann J, Kowalewski H, Vogel M, et al. Isolation of a Ca2+ or Mg2+-activated ATPase (ecto-ATPase) from bovine brain synaptic membranes. Biochim Biophys Acta. 1993;1152(1):146–154.
   PubMedGoogle Scholar
• Ben-Ari Y, Represa A. Trophic actions of GABA on neuronal development. Trends Neurosci. 2005;28(6):278–283.
   PubMed Web of Science ®Google Scholar
• Ward PE. Potential diagnostic aids for abnormal fatty acid metabolism in a range of neurodevelopmental disorders. Prostaglandins Leuko Essent Fatty Acids. 2000;63(1–2):65–68.
   PubMed Web of Science ®Google Scholar
• Rajasekaran A, Venkatasubramanian G, Berk M, et al. Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications. Neurosci Biobehav Rev. 2015;48:10–21.
   PubMed Web of Science ®Google Scholar
• Prabakaran S, Swatton JE, Ryan MM, et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry. 2004;9(7):684–697.
   PubMed Web of Science ®Google Scholar
• Fleckenstein AE, Volz TJ, Riddle EL, et al. New insights into the mechanism of action of amphetamines. Annu Rev Pharmacol Toxicol. 2007;47(1):681–698.
   PubMedGoogle Scholar
• Singh OP, Chakraborty I, Dasgupta A, et al. A comparative study of oxidative stress and interrelationship of important antioxidants in haloperidol and olanzapine treated patients suffering from schizophrenia. Indian J Psychiatry. 2008;50(3):171.
   PubMedGoogle Scholar
• Andreazza AC, Wang JF, Salmasi F, et al. Specific subcellular changes in oxidative stress in prefrontal cortex from patients with bipolar disorder. J Neurochem. 2013;127(4):552–561.
   PubMed Web of Science ®Google Scholar
• Gibson SA, Korade Z, Shelton RC. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J Psychiatr Res. 2012;46(10):1326–1332.
   PubMed Web of Science ®Google Scholar
• Chakraborty S, Singh OP, Dasgupta A, et al. Correlation between lipid peroxidation-induced TBARS level and disease severity in obsessive-compulsive disorder. Prog Neuro-Psychopharmacol Biol Psychiatry. 2009;33(2):363–366.
   PubMed Web of Science ®Google Scholar
• Pedrini M, Massuda R, Fries GR, et al. Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity. J Psychiatr Res. 2012;46(6):819–824.
   PubMed Web of Science ®Google Scholar
• Seibt KJ, da Luz Oliveira R, Rosemberg DB, et al. MK-801 alters Na+, K+-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs. J Neural Transm. 2012;119(6):661–667.
   PubMed Web of Science ®Google Scholar
• Koike S, Kayama T, Arai M, et al. Characterization of modified proteins in plasma from a subtype of schizophrenia based on carbonyl stress: protein carbonyl is a possible biomarker of psychiatric disorders. Biochem Biophys Res Commun. 2015;467(2):361–366.
   PubMed Web of Science ®Google Scholar
• Mathur NT, Varma M, Dixit VP. Hypolipidaemic and antiatherosclerotic effect of Celastrus Paniculatus seed extract (50% E + OH) in cholestrol. Indian Drugs-Bombay. 1993;30:76–76.
   Google Scholar
• Russo A, Izzo AA, Cardile V, et al. Indian medicinal plants as antiradicals and DNA cleavage protectors. Phytomedicine. 2001;8(2):125–132.
   PubMed Web of Science ®Google Scholar
• Sheth UK, Vaz A, Deliwala CV, et al. Behavioural and pharmacological studies of a tranquilising fraction from the oil of Celastrus paniculatus (Malkanguni oil). Arch Int Pharmacodyn Ther. 1963;144:34–50.
   PubMedGoogle Scholar
• Bala K, Tripathy BC, Sharma D. Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions. Biogerontology. 2006;7(2):81–89.
   PubMed Web of Science ®Google Scholar
• Kaul S, Krishnakanth TP. Effect of retinol deficiency and curcumin or turmeric feeding on brain Na+− K+ adenosine triphosphatase activity. Mol Cell Biochem. 1994;137(2):101–107.
   PubMed Web of Science ®Google Scholar
• Anbarasi K, Vani G, Balakrishna K, et al. Effect of bacoside A on membrane-bound ATPases in the brain of rats exposed to cigarette smoke. J Biochem Mol Toxicol. 2005;19(1):59–65.
   PubMed Web of Science ®Google Scholar
• Pierre S, Jamme I, Droy-Lefaix MT, et al. Ginkgo biloba extract (EGb 761) protects Na, K-ATPase activity during cerebral ischemia in mice. Neuroreport. 1999;10(1):47–51.
   PubMed Web of Science ®Google Scholar
• Ptacek LJ. Channelopathies: ion channel disorders of muscle as a paradigm for paroxysmal disorders of the nervous system. Neuromuscul Disord. 1997;7(4):250–255.
   PubMed Web of Science ®Google Scholar