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Hazard Assessment Articles

A Hazard Assessment of Aggregate Exposure to Nonylphenol and Nonylphenol Mono- and Di-ethoxylates in the Aquatic Environment

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Pages 1066-1094 | Received 01 Oct 2009, Accepted 09 Dec 2009, Published online: 11 Oct 2010

REFERENCES

  • Ahel , M and Giger , W . 1993 . Partitioning of alkylphenols and alkylphenol polyethoxylates between water and organic solvents . Chemosphere , 26 : 1471 – 8 .
  • Ahel , M , Giger , W and Schaffner , C . 1994 . Behavior of alkylphenol polyethoxylate surfactants in the aquatic environment—II. Occurrence and transformation in rivers . Water Res , 5 : 1143 – 52 .
  • Ankley , G T , Miller , D H Jensen , K M . 2008 . Relationship of plasma sex steroid concentrations in female fathead minnows to reproductive success and population status . Aquat Toxicol , 88 : 69 – 74 .
  • Ankley , G T , Bencic , D C Breen , M S . 2009 . Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action . Aquat Toxicol , 92 : 168 – 78 .
  • APERC (Alkylphenols and Ethoxylates Research Council) . 2006 . Alkylphenols and Alkylphenol Ethoxylates-Product Uses , Washington, DC, , USA : Alkylphenols and Ethoxylates Research Council . Available at http://www.aperc.org/productinfo.htm
  • Arslan , O C and Parlak , H . 2007 . Embryotoxic effects of nonylphenol and octylphenol in sea urchin Arbacia lixula . Ecotoxicology , 16 : 439 – 44 .
  • Arslan , O C , Parlak , H Oral , R . 2007 . The effects of nonylphenol and octylphenol on embryonic development of sea urchin (Paracentrotus lividus) . Arch Environ Contam Toxicol , 53 : 214 – 9 .
  • Arukwe , A and Goksoyr , A . 2003 . Eggshell and egg yolk proteins in fish: Hepatic proteins for the next generation: Oogenetic, population, and evolutionary implications of endocrine disruption . Comparative Hepatology , 2 : 4
  • Balch , G and Metcalfe , C . 2006 . Developmental effects in Japanese medaka (Oryzias latipes) exposed to nonylphenol ethoxylates and their degradation products . Chemosphere , 62 : 1214 – 23 .
  • Brennan , S J , Brougham , C A Roche , J J . 2006 . Multi-generational effects of four selected environmental oestrogens on Daphnia magna . Chemosphere , 64 : 49 – 55 .
  • Calabrese , E J and Baldwin , L A . 1993 . Performing Ecological Risk Assessments , Chelsea, MI, , USA : Lewis Publishers .
  • Cardinali , M , Maradonna , F Olivotto , I . 2004 . Temporary impairment of reproduction in freshwater teleost exposed to nonylphenol . Reprod Toxicol , 18 : 597 – 604 .
  • Christensen , J R , Richardson , J S Bishop , C A . 2005 . Effects of nonylphenol on rates of tail resorption and metamorphosis in Rana catesbeiana tadpoles . J Toxicol Environ Health , 68 : 557 – 72 .
  • Corvini , P F , Schaffer , A and Schlosser , D . 2006 . Microbial degradation of nonylphenol and other alkylphnols—Our evolving view . Appl Microbiol Biotechnol , 72 : 223 – 43 .
  • Coutellec , M , Delous , G Cravedi , J . 2008 . Effects of the mixture of diquat and a nonylphenol polyethoxylate adjuvant on fecundity and progeny early performances of the pond snail Lymnaea stagnalis in laboratory bioassays and microcosms . Chemosphere , 73 : 326 – 36 .
  • Czech , P , Weber , K and Dietrich , D R . 2001 . Effects of endocrine modulating substances on reproduction in the hermaphroditic snail Lymnaea stagnalis L . Aquat Toxicol , 53 : 103 – 14 .
  • Dussault , E B , Sherry , J P Lee , H B . 2005 . In vivo estrogenicity of nonylphenol and its ethoxylates in the Canadian environment . Hum Ecol Risk Assess , 11 : 353 – 64 .
  • England , D E . 1995a . “ Chronic Toxicity of Nonylphenol to Ceriodaphnia dubia ” . Final Report 41756. ABC Laboratories, Inc, Columbia, MO, USA
  • England , DE. 1995b . “ . Chronic Toxicity of NPE 1.5 to Ceriodaphnia dubia ” . Final Report 41766. ABC Laboratories, Inc, Columbia, MO, USA
  • Environment Canada . 2007 . A Protocol for the Derivation of Water Quality Guidelines for the Protection of Aquatic Life 2007, WQG-PAL Gatineau, QC, , Canada Available at http://ceqg-rcqe.ccme.ca/
  • Environment Canada and Health Canada . 2001 . Nonylphenol and its Ethoxylates, PSL-2 Risk Assessment Gatineau, Quebec, , Canada Available at http://www.hc-sc.gc.ca/ewh-semt/pubs/contaminants/psl2-lsp2/nonylphenol/index_e.html
  • European Union . 2002 . “ European Union Risk Assessment Report: 4-Nonylphenol (branched) and Nonylphenol ” . Office for Official Publications of the European Communities, Luxembourg. Available at http--ecb.jrc.ec.europa.eu-DOCUMENTS-Existing-Chemicals-RISK_ASSESSMENT-REPORT-4nonylphenol_nonylphenolreport017.pdf
  • Fent , K , Ackermann , G E and Schwaiger , J . 1999 . “ Analysis of vitellogenin mRNA by quantitative reverse transcription polymerase chain reaction (RT-PCR) in juvenile fish exposed for twelve months to nonylphenol ” . In Proceedings of the 10th International Symposium on Pollutant Response in Marine Organisms (PRIMO 10) Williamsburg, VA, , USA April 25–29
  • Forget-Leray , J , Landriau , I Minier , C . 2005 . Impact of endocrine toxicants on survival, development, and reproduction of the estuarine copepod Eurytemora affinis (Poppe) . Ecotoxicol Environ Saf , 60 : 288 – 94 .
  • Ghirardini , A V , Novelli , A A Likar , B . 2001 . Sperm cell toxicity test using sea urchin Paracentrotus lividus Lamarck (Echinodermata: Echinoidea): Sensitivity and discriminatory ability toward anionic and nonionic surfactants . Environ Toxicol Chem , 20 : 644 – 51 .
  • Granmo , A , Ekelund , R Magnusson , K . 1989 . Lethal and sublethal toxicity of 4-nonylphenol to the common mussel (Mytilus edulis L.) . Environ Poll , 59 : 115 – 27 .
  • Gray , M A and Metcalfe , C D . 1997 . Induction of testis-ova in Japanese medaka (Oryzias latipes) exposed to p-nonylphenol . Environ Toxicol Chem , 16 : 1082 – 6 .
  • Hagger , J A , Jobling , S Depledge , M . 2004 . The genotoxic and immunotoxic effects of endocrine disrupting chemicals (EDCs) on the marine molluscs, Nucella lapillus (Dogwhelk) and Mytilus edulis (common blue mussel) . Mar Environ Res , 58 : 777 – 8 .
  • Hirano , M , Ishibashi , H Kim , J-W . 2009 . Effects of environmentally relevant concentrations of nonylphenol on growth and 20-hydroxyecdysone levels in mysid crustacean, Americamysis bahia . Comp Biochem Physiol, Part C: Toxicol Pharmacol , 149 : 368 – 73 .
  • Hutchinson , T H , Ankley , G T Segner , H . 2006 . Screening and testing for endocrine disruption in fish—Biomarkers as “signposts” not “traffic lights” in risk assessment . Environ Health Perspect , 114 : 106 – 14 .
  • IGHRC (The Interdepartmental Group on Health Risks from Chemicals) . 2009 . Chemical Mixtures: A Framework for Assessing Risk to Human Health (CR14) , UK : Institute of Environment and Health, Cranfield University .
  • Isidori , M , Lavorgna , M Nardelli , A . 2006 . Toxicity on crustaceans and endocrine disrupting activity on Saccharomyces cerevisiae of eight alkylphenols . Chemosphere , 64 : 135 – 43 .
  • Islinger , M , Pawlowski , S Hollert , H . 1999 . Measurement of vitellogenin-mRNA expression in primary cultures of rainbow trout hepatocytes in a non-radioactive dot blot/RNAse protection-assay . Sci Total Environ , 233 : 109 – 22 .
  • Jobling , S and Sumpter , J P . 1993 . Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus mykiss) . Aquat Toxicol , 27 : 661 – 72 .
  • Jobling , S , Sheahan , D and Osborne , J A . 1996 . Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicals . Environ Toxicol Chem , 15 : 194 – 202 .
  • Julius , M L , Stepanek , J Tedrow , O . 2007 . Estrogen-receptor independent effects of two ubiquitous environmental estrogens on Melosira varians Agardh, a common component of the aquatic primary production community . Aquat Toxicol , 85 : 19 – 27 .
  • Kim , I C , Lee , Y M Lee , C . 2006 . Expression profiles of 4-nonylphenol-exposed medaka (Oryzias latipes) analyzed with a 3.4 K microarray . Mar Environ Res , 62 : S141 – S146 .
  • Klecka , G M , Zabik , J and Woodburn , K . 2007 . Exposure analysis of C8- and C9-alkylphenol, alkylphenol ethoxylates and their metabolites in surface water systems within the United States . Hum Ecol Risk Assess , 13 : 792 – 822 .
  • Klecka , G M , Staples , C A Naylor , C G . 2008 . C8- and C9-alkylphenols and ethoxylates: II. Assessment of environmental persistence and bioaccumulation potential . Hum Ecol Risk Assess , 14 : 1025 – 55 .
  • Konemann , W H and Pieters , M N . 1996 . Confusion of concepts in mixture toxicology . Food Chem Toxicol , 34 : 1025 – 31 .
  • Lalah , J O , Severin , G F Schramm , K W . 2007 . Effects of a branched p-nonylphenol isomer (4(3′6′-dimethyl-3′-heptyl)-phenol) on embryogenesis in Lymnae stagnalis L . Arch Environ Contam Toxicol , 52 : 104 – 12 .
  • Larsen , B K , Bjornstad , A Sundt , R C . 2006 . Comparison of protein expression in plasma from nonylphenol and bisphenol A-exposed Atlantic cod (Gadus morhua) and turbot (Scophthalmus maximus) by use of SELDI-TOF . Aquat Toxicol , 78 : S25 – S33 .
  • Lee , C , Na , J G Lee , K C . 2002 . Choriogenin mRNA induction in male medaka, Oryzias latipes, as a biomarker of endocrine disruption . Aquat Toxicol , 61 : 233 – 41 .
  • Lee , P C and Lee , W . 1996 . In vivo estrogenic action of nonylphenol in immature female rats . Bull Environ Contam Toxicol , 57 : 341 – 8 .
  • Lee , S-M , Park , C-H and Choi , J . 2006 . Expression of heat shock protein and hemoglobin genes in Chironomus tentans (Diptera, chironomidae) larvae exposed to various environmental pollutants: A potential biomarker of freshwater monitoring . Chemosphere , 65 : 1074 – 81 .
  • Leino , R L , Jensen , K M and Ankley , G T . 2005 . Gonadal histology and characteristic histopathology associated with endocrine disruption in the adult fathead minnow (Pimephales promelas) . Environ Toxicol Pharmacol , 19 : 85 – 98 .
  • Lerner , D T , Bjornsson , B T and McCormick , S D . 2007a . Aqueous exposure to 4-nonylphenol and 17beta-estradiol increases stress sensitivity and disrupts ion regulatory ability of juvenile Atlantic salmon . Environ Toxicol Chem , 26 : 1433 – 40 .
  • Lerner , D T , Bjornsson , B T and McCormick , S D . 2007b . Larval exposure to 4-nonylphenol and 17beta-estradiol affects physiological and behavioral development of seawater adaptation in Atlantic salmon smolts . Environ Sci Technol , 41 : 4479 – 85 .
  • Li , MH. 2008a . Effects of nonylphenol on cholinesterase and carboxylesterase activities in male guppies . Ecotoxicol Environ Saf , 71 : 781 – 6 .
  • Li , MH. 2008b . Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian . Chemosphere , 70 : 1796 – 803 .
  • Li , M H and Wang , Z R . 2005 . Effect of nonylphenol on plasma vitellogenin of male adult guppies (Poecilia reticulate) . Environ Toxicol , 20 : 53 – 9 .
  • Lin , L L and Janz , D M . 2006 . Effects of binary mixtures of xenoestrogens on gonadal development and reproduction in zebrafish . Aquat Toxicol , 80 : 382 – 95 .
  • Lloyd , R. 1982 . “ The toxicity of mixtures of chemicals to fish: An overview of European laboratory and field experience ” . In Environmental Hazard of Effluents , Edited by: Bergman , H L , Kimerle , R A and Maki , A W . New York, NY, , USA : John Wiley and Sons .
  • Luo , Q , Ban , M Ando , H . 2005 . Distinct effects of 4-nonylphenol and 17β-estradiol on expression of estrogen receptor α gene in smolting sockeye salmon . Comp Biochem Physiol, Part C: Toxicol Pharmacol , 140C : 123 – 30 .
  • Marcial , H S and Hagiwara , A . 2007 . Multigenerational effects of 17β-estradiol and nonylphenol on euryhaline cladoceran Diaphanosoma celebensis . Fish Sci (Carlton, Aust) , 73 : 324 – 30 .
  • Martin-Skilton , R , Thibaut , R and Porte , C . 2006 . Endocrine alteration in juvenile cod and turbot exposed to dispersed crude oil and alkylphenols . Aquat Toxicol , 78S : S57 – S64 .
  • Matozzo , V and Marin , M G . 2005 . Can 4-nonylphenol induce vitellogenin-like proteins in the clam Tapes philippinarum? . Environ Res , 97 : 43 – 9 .
  • Matozzo , V , Gagne , F Marin , M G . 2008 . Vitellogenin as a biomarker of exposure to estrogenic compounds in aquatic invertebrates: A review . Environment International , 34 : 531 – 45 .
  • Metcalfe , C D , Metcalfe , T L Kiparissis , Y . 2001 . Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes) . Environ Toxicol Chem , 20 : 297 – 308 .
  • Miles-Richardson , S R , Pierens , S L Nichols , K M . 1999 . Effects of waterborne exposure to 4-nonylphenol and nonylphenol ethoxylate on secondary sex characteristics and gonads of fathead minnows (Pimephales promelas) . Environ Res , 80 : S122 – S137 .
  • Miller , D H , Jensen , K M Villeneuve , D L . 2007 . Linkage of biochemical responses to population-level effects: A case study with vitellogenin in the fathead minnow (Pimephales promelas) . Environ Toxicol Chem , 26 : 521 – 7 .
  • Moore , A , Scott , A P Lower , N . 2003 . The effects of 4-nonylphenol and atrazine on Atlantic salmon (Salmo salar L.) smolts . Aquaculture , 222 : 253 – 63 .
  • Nice , H E , Thorndyke , M C Morritt , D . 2000 . Development of Crassostrea gigas larvae is affected by 4-nonylphenol . Mar Pollut Bull , 40 : 491 – 6 .
  • Nice , H E , Crane , M and Morritt , D . 2001 . “ Endocrine disrupters, critical windows and developmental success in oyster larvae ” . In Environment and Animal Development , Edited by: Atkinson , D and Thorndyke , M . 203 – 17 . Oxford, , UK : BIOS Scientific Publishers .
  • Nice , H E , Morritt , D Crane , M . 2003 . Long-term and transgenerational effects of nonylphenol exposure at a key stage in the development of Crassostrea gigas. Possible endocrine disruption? . Marine Ecology: Progress Series , 256 : 293 – 300 .
  • Osada , M , Takamura , T Sato , H . 2003 . Vitellogenin synthesis in the ovary of the scallop, Patinopecten yessoensis: Control by estradiol-17β and the central nervous system . J Exp Zool , 299A : 172 – 9 .
  • Price , PS. 2010 . “ Synergy a risk management perspective ” . In Principles and Practice of Mixtures Toxicology , Edited by: Mumtaz , M . Wiley Interscience .
  • Quinn , B , Gagne , F Blaise , C . 2006 . Evaluation of the lethal and sub-lethal toxicity and potential endocrine disrupting effect of nonylphenol on the zebra mussel (Dreissena polymorpha) . Comp Biochem Physiol, Part C: Toxicol Pharmacol , 142 : 118 – 27 .
  • Rub , A S , Vinken , R Schupan , I . 2005 . Synthesis of branched para-nonylphenol isomers: Occurrence and quantification in two commercial mixtures . Chemosphere , 60 : 1624 – 35 .
  • Seki , M , Yokota , H Maeda , M . 2003 . Effects of 4-nonylphenol and 4-tert-octylphenol on sex differentiation and vitellogenin induction in medaka (Oryzias latipes) . Environ Toxicol Chem , 22 : 1507 – 16 .
  • Servos , MR. 1999 . Review of the aquatic toxicity, estrogenic responses and bioaccumulation of alkylphenols and alkylphenol polyethoxylates . Water Qual Res J Can , 34 : 123 – 77 .
  • Servos , M R , Maguire , R J Bennie , D T . 2000 . “ Supporting document for nonylphenol and its ethoxylates under the Priority Substance List, Canadian Environmental Protection Act ” . Environment Canada, NWRI Contribution 00-029, Toxics Pollution Prevention Directorate, Commercial Chemicals Evaluation Branch, Ottawa, Canada
  • Severin , G E , Welzl , G Juttner , I . 2003 . Effects of nonylphenol on zooplankton in aquatic microcosms . Environ Toxicol Chem , 22 : 2733 – 8 .
  • Soares , A. , Guieysse , B Jefferson , B . 2008 . Nonylphenol in the environment: A critical review on occurrence, fate, toxicity and treatment in wastewaters . Environ Internat , 34 : 1033 – 49 .
  • Sousa , JV. 1999 . Nonylphenol-1.5EO- Chronic Toxicity to Mysids (Mysidopsis bahia) under Flow-Through Conditions , Wareham, MA, , USA : Prepared for APE Research Council by Springborn Laboratories, Inc . SLI Report No. 98-10-7497
  • Staples , C , Mihaich , E Carbone , J . 2004 . A weight of evidence analysis of the chronic ecotoxicity of nonylphenol ethoxylates, nonylphenol ether carboxylates, and nonylphenol . Hum Ecol Risk Assess , 10 : 999 – 1017 .
  • Staples , C A , Klecka , G M Naylor , C G . 2008 . C8- and C9-alkylphenols and ethoxylates: I. Identity, physical characterization, and biodegradation pathways analysis . Hum Ecol Risk Assess , 14 : 1007 – 24 .
  • Sturve , J , Hasselberg , L Falth , H . 2006 . Effects of North Sea oil and alkylphenols on biomarker responses in juvenile Atlantic cod (Gadus morhua) . Aquat Toxicol , 78 : S73 – S78 .
  • Sumpter , J P and Jobling , S . 1995 . Vitellogenesis as a biomarker of estrogenic contamination in the aquatic environment . Environ Health Perspect , 103 : 173 – 8 .
  • Sun , H and Gu , X . 2005 . Comprehensive toxicity study of nonylphenol and short chain nonylphenol polyethoxylates on Daphnia magna . Bull Environ Contam Toxicol , 75 : 677 – 83 .
  • Talmage , SS. 1994 . Environmental and Human Safety of Major Surfactants. Alcohol Ethoxylates and Alkylphenol Ethoxylates , Boca Raton, FL, , USA : Lewis Publishers .
  • TenEyck , M C and Markee , T P . 2007 . Toxicity of nonylphenol, nonylphenol monoethoxylate, and nonylphenol diethoxylate and mixtures of these compounds to Pimephales promelas (Fathead minnow) and Ceriodaphnia dubia . Arch Environ Contam Toxicol , 53 : 599 – 606 .
  • Thorpe , K L , Benstead , R Hutchinson , T H . 2007 . Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow (Pimephales promelas) . Aquat Toxicol , 85 : 176 – 83 .
  • USEPA (US Environmental Protection Agency) . 2005 . Aquatic Life Ambient Water Quality Criteria—Nonylphenol Washington, DC, , USA Report 822-R-05-005
  • USEPA . 2009 . ECOWIN v. 1.00, ECOSAR Classes for Microsoft Windows, OPPT-Risk Assessment Division Washington, DC, , USA
  • Vaccaro , E , Meucci , V Intorre , L . 2005 . Effects of 17β-estradiol, 4-nonylphenol and PCB 126 on the estrogenic activity and phase 1 and 2 biotransformation enzymes in male sea bass (Dicentrarchus labrax) . Aquat Toxicol , 75 : 293 – 305 .
  • Van Den Belt , K , Berckmans , P Vangenechten , C . 2004 . Comparative study on the in vitro/in vivo estrogenic potencies of 17β-estradiol, estrone, 17α-ethynylestradiol and nonylphenol . Aquat Toxicol , 66 : 183 – 95 .
  • Ward , T J and Boeri , R L . 1991 . Chronic Toxicity of Nonylphenol to the Mysid (Mysidopsis bahia) , Hampton, NH, , USA : Prepared for the Chemical Manufacturers Association by Resource Analysts . Study No. 8977-CMA
  • Wheeler , T F , Heim , J R LaTorre , M R . 1997 . Mass spectral characterization of p-nonylphenol isomers using high-resolution capillary GC-MS . J Chromatogr Sci , 35 : 19 – 30 .
  • Yang , F X , Xu , Y and Wen , S . 2005 . Endocrine-disrupting effects of nonylphenol, bisphenol A, and p,p’-DDE on Rana nigromaculata tadpoles . Bull Environ Contam Toxicol , 75 : 1168 – 75 .
  • Yang , F X , Xu , Y and Hui , Y . 2006 . Reproductive effects of prenatal exposure to nonylphenol on zebrafish (Danio rerio) . Comp Biochem Physiol, Part C: Toxicol Pharmacol , 142 : 77 – 84 .
  • Yoshimura , K. 1986 . Biodegradation and fish toxicity of nonionic surfactants . J Am Oil Chem Soc , 63 : 1590 – 6 .
  • Zha , J , Wang , Z Wang , N . 2007 . Histological alteration and vitellogenin induction in adult rare minnow (Gobiocypris rarus) after exposure to ethinylestradiol and nonylphenol . Chemosphere , 66 : 488 – 95 .
  • Zha , J , Sun , L Spear , P A . 2008 . Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus) . Ecotoxicol Environ Safety , 71 : 390 – 9 .
  • Zhang , L , Gibble , R and Baer , K N . 2003 . The effects of 4-nonylphenol and ethanol on acute toxicity, embryo development, and reproduction in Daphnia magna . Ecotoxicol Environ Saf , 55 : 330 – 7 .
  • Zhang , Z , Hu , J An , W . 2005 . Induction of vitellogenin mRNA in juvenile Chinese sturgeon (Acipenser sinensis Gray) treated with 17β-estradiol and 4-nonylphenol . Environ Toxicol Chem , 24 : 1944 – 50 .
  • Zhao , B , Liu , Z Xu , Z . 2005 . Estrogenic effects of phenolic compounds on juvenile goldfish (Carassius auratus) . Huanjing Kexue Xuebao , 25 : 1259 – 64 .

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