209
Views
53
CrossRef citations to date
0
Altmetric
Original Articles

Drug Screening Using Microextraction in a Packed Syringe (MEPS)/Mass Spectrometry Utilizing Monolithic‐, Polymer‐, and Silica‐Based Sorbents

, , &
Pages 829-839 | Received 15 Jun 2005, Accepted 18 Nov 2005, Published online: 06 Feb 2007

References

  • Current Patent Gazette . week 0310, WO03019149 . 2003 . 77
  • Abdel‐Rehim , M. 2004 . New trends in sample preparation: Online microextraction in packed syringe for liquid and gas chromatography applications. I. Determination of local anaesthetics in human plasma samples using gas chromatography—mass spectrometry . J. Chromatogr. B. , 801 : 317 – 321 .
  • Abdel‐Rehim , M. , Altun , Z. and Blomberg , L. 2004 . Microextraction in packed syringe (MEPS) for liquid and gas chromatographic applications. Part II—Determination of ropivacaine and its metabolites in human plasma samples using MEPS with liquid chromatography/tandem mass spectrometry . J. Mass Spectrom. , 39 : 1488 – 1493 .
  • Altun , Z. , Abdel‐Rehim , M. and Blomberg , L. G. 2004 . New trends in sample preparation: on‐line microextraction in packed syringe (MEPS) for LC and GC applications. Part III: Determination and validation of local anaesthetics in human samples using cation‐exchange sorbent, and MEPS‐LC‐MS‐MS . J. Chromatogr. B. , 813 : 129 – 135 .
  • Iberer , G. , Hahn , R. and Jungbauer , A. 1999 . Monoliths as stationary phases for separating biopolymers—Fourth‐Generation Chromatography Sorbents . LC‐GC, Nov. , 17 ( 11 ) : 998
  • Tennikova , T. B. , Belenkii , B. G. and Svec , F. 1990 . High‐Performance membrane chromatography. A novel method of protein separation . J. Liq. Chrom. , 13 ( 1 ) : 63 – 70 .
  • Švec , F. and Fréchet , J. M.J. 1992 . Continuous rods of macroporous polymer as high‐performance liquid chromatography separation media . Anal. Chem. , 64 : 820 – 822 .
  • Ledigo‐Quegley , C. , Marlin , N. D. , Melin , V. , Manz , A. and Smith , N. W. 2003 . Advances in capillary electro chromatography and micro‐high performance liquid chromatography monolithic columns for separation science . Electrophoresis , 24 : 917 – 944 .
  • Pan , Z. , Zou , H. , Mo , W. , Huang , X. and Wu , R. 2002 . Protein A immobilized monolithic capillary column for affinity chromatography . Anal. Chem. Acta , 466 : 141 – 150 .
  • Lämmerhofer , M. , Svec , F. , Frechét , J. M.J. and Lindner , W. 2001 . Capillary electrochromatography in anion‐exchange and normal‐phase mode using monolithic stationary phases . J. Chromatogr. A , 925 : 265 – 277 .
  • Tennikova , T. B. , Bleha , M. , Svec , F. , Almazova , T. V. and Belenki , B. G. 1991 . High‐performance membrane chromatography of proteins, a novel method of protein separation . J. Chromatogr. , 555 : 97 – 107 .
  • Merhar , M. , Podgornik , A. , Barut , M. , Zigon , M. and Strancar , A. 2003 . Methacrylate monolithic prepared from various hydrophobic and hydrophilic monomers—Structural and chromatographic characteristics . J. Sep. Sci. , 26 : 322 – 330 .
  • Viklund , C. , Svec , F. , Fréchet , J. M.J. and Irgum , K. 1996 . Monolithic, “Molded”, porous materials with high flow characteristics for separations, catalysis, or solid‐phase chemistry: control of porous properties during polymerization . Chem. Mater. , 8 : 744 – 750 .
  • Svec , F. and Frechet , J. M.J. 1999 . Molded Rigid monolithic porous polymers: An inexpensive, efficient, and versatile alternative to beads for the design of materials for numerous applications . Ind. Eng. Chem. Res. , 38 : 34 – 48 .
  • Tanaka , N. , Nagayama , H. , Kobayashi , H. , Ikegami , T. , Hosoya , K. , Ishizuka , N. , Minakuch , H. , Nakanishi , K. , Cabrera , K. and Lubda , D. 2000 . Monolithic Silica Columns for HPLC, Micro‐HPLC, and CEC . J. High Resol. Chromatogr. , 23 ( 1 ) : 111 – 116 .
  • Hiroyoshi , M. , Nakanishi , K. , Soga , N. , Norio , I. and Tanaka , N. 1996 . Octadecylsilylated porous silica rods as separation media for reversed‐phase liquid chromatography . Anal. Chem. , 68 : 3498 – 3501 .
  • Tanaka , N. , Kobayashi , H. , Ishizuka , N. , Minakuchi , H. , Nakanishi , K. , Hosoya , K. and Ikegami , T. 2002 . Monolithic silica columns for high‐efficiency chromatographic separations . J. Chromatogr. A , 965 : 35 – 49 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.