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Original Articles

Fast and Efficient Separations Using Reversed Phase Liquid Chromatography

&
Pages 949-988 | Received 06 Oct 2005, Accepted 20 Dec 2005, Published online: 06 Feb 2007

References

  • Katz , E. and Scott , R. P.W. 1982 . Liquid chromatography system for fast, accurate analysis . Chromatogr. A , 253 : 159 – 178 .
  • Chen , H. and Horváth , Cs. 1995 . High speed high‐performance liquid chromatography of peptides and proteins . J. Chromatogr. A , 705 : 3 – 20 .
  • Weber , L. 2004 . In vitro combinatorial chemistry to create drug candidates . Drug Disc. Today Technol. , 1 : 261 – 267 .
  • Czarnik , A. W. and Keene , J. D. 1998 . Combinatorial chemistry . Current Biol. , 8 : R705 – 707 .
  • Kennedy , R. T. , German , I. , Thompson , J. E. and Witowski , S. R. 1999 . Fast analytical‐scale separations by capillary electrophoresis and liquid chromatography . Chem. Rev. , 99 : 3081 – 3031 .
  • Swartz , M. E. 2005 . UPLC. An introduction and review . J. Liq. Chromatogr. & Rel. Tech. , 28 : 1253 – 1263 .
  • Kyranos , J. N. and Hogan , J.C. Jr. 1998 . High‐throughput characterization of combinatorial libraries generated by parallel synthesis . Anal. Chem. , 70 : 389 – 395A .
  • Guiochon , G. 1978 . Speed of analysis in open tubular column gas chromatography . Anal. Chem. , 50 : 1812
  • Van Deemter , J. J. , Zuiderweg , F. J. and Kinkenberg , A. 1956 . Longitudinal diffusion and resistance to mass transfer as causes of nonideality in chromatography . Chem. Eng. Sci. , 5 : 271 – 289 .
  • Snyder , L. R. and Kirkland , J. J. 1979 . Introduction to Modern Liquid Chromatography New York : John Wiley .
  • Rothman , D. L. 1996 . Column liquid chromatography: equipment and instrumentation . Anal. Chem. , 68 : 587 – 598R .
  • Lacourse , W. R. and Dasenbrock , C. O. 1998 . Column liquid chromatography: Equipment and instrumentation . Anal. Chem. , 70 : 37R
  • Giddings , J. C. 1991 . Unified Separation Science 65 New York : John Wiley .
  • MacNair , J. E. , Lewis , K. C. and Jorgenson , J. W. 1997 . Ultrahigh‐pressure reversed‐phase liquid chromatography in packed capillary columns . Anal. Chem. , 69 : 983 – 989 .
  • Wu , N. , Collins , D. C. , Lippert , J. A. , Xiang , Y. and Lee , M. L. 2000 . Ultrahigh pressure liquid chromatography/time‐of‐flight mass spectrometry for fast separations . J. Microcol. Sepn. , 12 : 462 – 469 .
  • Wu , N. , Lippert , J. A. and Lee , M. L. 2001 . Practical aspects of ultrahigh pressure capillary liquid chromatography . J. Chromatogr. A , 911 : 1 – 12 .
  • Poppe , H. 1997 . Some reflections on speed and efficiency of modern chromatographic methods . J. Chromatogr. A. , 778 : 3 – 21 .
  • Dittmann , M. M. and Rozing , G. P. 1996 . Capillary electrochromatography—a high‐efficiency micro‐separation technique . J. Chromatogr. A , 744 : 63 – 74 .
  • Hileman , F. D. , Sievers , R. E. , Hess , G. G. and Ross , W. D. 1973 . In situ preparation and evaluation of open pore polyurethane chromatographic columns . Anal. Chem. , 45 : 1126 – 1130 .
  • Hansen , L. C. and Sievers , R. E. 1974 . Highly permeable open‐pore polyurethane columns for liquid chromatography . J. Chromatogr. , 99 : 123 – 133 .
  • Kele , M. and Guichon , G. 2002 . Repeatability and reproducibility of retention data and band profiles on six batches of monolithic columns . J. Chromatogr. A , 960 : 19 – 49 .
  • Tanaka , N. , Kobayashi , H. , Ishizuka , N. , Minakuchi , H. , Nakanishi , K. , Hosoya , K. and Ikegami , T. 2002 . Monolithic silica columns for high‐efficiency chromatographic separations . J. Chromatogr. A , 965 : 35 – 49 .
  • McCalley , D. V. 2002 . Comparison of conventional microparticulate and a monolithic reversed‐phase column for high‐efficiency fast liquid chromatography of basic compounds . J. Chromatogr. A , 965 : 51 – 64 .
  • Ikegami , T. and Tanaka , N. 2004 . Monolithic columns for high‐efficiency HPLC separations . Cur. Opin. in Chem. Biol. , 8 : 527 – 533 .
  • Cabrera , K. 2004 . Applications of silica‐based monolithic HPLC columns . J. Sepn. Sci. , 27 : 843 – 852 .
  • Wilke , C. R. and Chang , P. 1955 . Correlation of diffusion coefficients in dilute solutions . Am. Inst. Chem. Eng. J. , 1 : 264 – 270 .
  • Anitia , F. and Horváth , Cs. 1988 . High‐performance liquid chromatography at elevated temperatures: examination of conditions for the rapid separation of large molecules. J . Chromatogr. A , 435 : 1 – 15 .
  • Snyder , L. R. 2000 . HPLC past and present . Anal. Chem. , 72 : 412 – 420A .
  • MacNair , J. E. , Patel , K. D. and Jorgenson , J. W. 1999 . Ultrahigh‐pressure reversed‐phase capillary liquid chromatography: Isocratic and gradient elution using columns packed with 1.0‐µm particles . Anal. Chem. , 71 : 700 – 708 .
  • Xiang , Y. , Wu , N. , Lippert , A. J. and Lee , M. L. 2002 . Separation of chiral parmaceuticals using ultrahigh pressure liquid chromatography . Chromatographia , 55 : 399 – 403 .
  • Issaeva , T. , Kourganov , A. and Unger , K. 1999 . Super‐high speed liquid chromatography of proteins and peptides on non‐porous Micra NPS‐RP packings . J. Chromatogr. A , 846 : 13 – 23 .
  • Cintron , J. M. and Colon , L. A. 2002 . Organo‐silica nano‐particles used in ultra high‐pressure liquid chromatography . Analyst , 127 : 701 – 704 .
  • Xiang , Y. , Yan , B. , Yue , B. , McNeff , C. V. , Carr , P. W. and Lee , M. L. 2003 . Elevated‐temperature ultrahigh‐pressure liquid chromatography using very small polybutadiene‐coated nonporous zirconia particles . J. Chromatogr. A , 983 : 83 – 89 .
  • Mellors , J. S. and Jorgenson , J. W. 2004 . Use of 1.5 µm porous ethyl‐bridged hybrid particles as a stationary‐phase support for reversed‐phase ultrahigh‐pressure liquid chromatography . Anal. Chem. , 76 : 5441 – 5450 .
  • Lee , M. L. , Barnett , H. , Brisbin , M. P. , Liu , Y. , Liu , J. , Plistil , A. , Stearns , S. D. and Xiang , Y. 2005 . “ Practicability of ultrahigh pressure LC for fast separation. Pittcon 2005 ” . Orlando, Florida
  • Swartz , M. E. 2005 . UPLC. An introduction and review . J. Liq. Chromatgr. & Rel. Technol. , 28 : 1253 – 1263 .
  • Swartz , M. E. and Murphy , B. 2005 . New frontiers in chromatography . Am. Lab. , 37 : 22 – 27 .
  • Plumb , R. S. , Granger , J. H. , Stumpf , C. L. , Johnson , K. A. , Smith , B. W. , Gaulitz , S. , Wilson , I. D. and Castro‐Perez , J. 2005 . A rapid screening approach to metabonomics using UPLC and oa‐TOF mass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice . Analyst , 130 : 844 – 849 .
  • Castro‐Perez , J. , Beattie , I. , Joncour , K. , Wright , A. , Granger , J. , Baker , A. and Plumb , R. 2005 . New ULTRA‐HTS/UPLC‐MS method for detecting and identifying metabolites . Noticias Tecnicas del Laboratorio , 13 : 22 – 25 .
  • Johnson , K. A. and Plumb , R. 2005 . Investigating the human metabolism of acetaminophen using UPLC and exact mass oa‐TOF MS . J. Pharm. Biomed. Anal. , 39 : 805 – 810 .
  • Castro‐Perez , J. , Plumb , R. , Granger , J. H. , Beattie , I. , Joncour , K. and Wright , A. 2005 . Increasing throughput and information content for in vitro drug metabolism experiments using ultra‐performance liquid chromatography coupled to a quadrupole time‐of‐flight mass spectrometer . Rapid Commun. Mass Spec. , 19 : 843 – 848 .
  • Wilson , I. D. , Plumb , R. , Granger , J. , Major , H. , Williams , R. and Lenz , E. M. 2005 . HPLC‐MS‐based methods for the study of metabonomics . J. Chromatogr. B , 817 : 67 – 76 .
  • King , S. , Stoffolano , P. J. , Robinson , E. , Eichhold , T. E. , Hoke , S. H. , II; Baker , T. R. , Richarson , E. C. and Wehmeyer , K. R. 2005 . The evaluation and application of UPLC for the rapid analysis of dose formulations . LC · GC (Europe) , : 33 – 36 .
  • Jerkovich , A. D. , LoBrutto , R. and Vivilecchia , R. V. 2005 . The use of ACQUITY UPLC in pharmaceutical development . LC · GC , : 15 – 21 .
  • Wren , S. A.C. 2005 . Peak capacity in gradient ultra performance liquid chromatography (UPLC) . J. Pharm. Biomed. Anal. , 38 : 337 – 343 .
  • Yang , Y. and Hodges , C. C. 2005 . Assay transfer from HPLC to UPLC for higher analysis throughput . LC · GC (Europe) , : 28 – 32 .
  • Tanaka , N. , Nagayama , H. , Kobayashi , H. , Ikegami , T. , Hosoya , K. , Ishizuka , N. , Minakuchi , H. , Nakanishi , K. , Cabrera , K. and Lubda , D. 2000 . Monolithic silica columns for HPLC, micro‐HPLC, and CEC . J. High Resolut. Chromatogr. , 23 : 111 – 116 .
  • Fields , S. M. 1996 . Silica xerogel as a continuous column support for high‐performance liquid chromatography . Anal. Chem. , 68 : 2709 – 2712 .
  • Svec , F. 2004 . Preparation and HPLC applications of rigid macroporous organic polymer monoliths . J. Sepn. Sci. , 27 : 747 – 766 .
  • Hjerten , S. , Liao , J. L. and Zhang , R. 1989 . High‐performance liquid chromatography on continuous polymer beds . J. Chromatogr. , 473 : 273 – 275 .
  • Xie , S. , Allington , R. W. , Svec , F. and Frechet , J. M.J. 1999 . Rapid reversed‐phase separation of proteins and peptides using optimized ‘moulded’ monolithic poly(styrene‐co‐divinylbenzene) columns . J. Chromatogr. A , 865 : 169 – 174 .
  • Gusev , I. , Huang , X. and Horvath , C. 1999 . Capillary columns with in situ formed porous monolithic packing for micro high‐performance liquid chromatography and capillary electrochromatography . J. Chromatogr. A , 855 : 273 – 290 .
  • Tang , Q. , Wu , N. and Lee , M. L. 2000 . Continuous‐bed columns containing sol‐gel bonded octadecylsilica for capillary liquid chromatography . J. Microcol. Sepn. , 12 : 6 – 12 .
  • Tang , Q. and Lee , M. L. 2003 . Monolithic columns prepared from particles . J. Chromatogr. Lib. , 67 : 197 – 211 . Monolithic Materials
  • Tang , Q. , Wu , N. , Yue , B. and Lee , M. L. 2005 . Small diameter (3 µm), large pore (1500/) octadecylsilica for capillary electrochromatography . Chromatographia , 61 : 345 – 350 .
  • Tang , Q. , Shen , Y. , Wu , N. and Lee , M. L. 1999 . Situ crosslinked polybutadiene‐coated zirconia as a monolithic column for fast SGC . J. Microcol. Sepn. , 11 : 415 – 420 .
  • Tang , Q. and Lee , M. L. 2000 . Continuous‐bed columns containing sol‐gel bonded packing materials for capillary electrochromatography . J. High Resol. Chromatogr. , 23 : 73 – 80 .
  • Tennikova , T. B. and Svec , F. 1993 . High‐performance membrane chromatography: Highly efficient separation method for proteins in ion‐exchange, hydrophobic interaction and reversed‐phase modes . J. Chromatogr. A. , 646 : 279 – 288 .
  • Liang , C. , Dai , S. and Guiochon , G. 2003 . A Graphitized‐carbon monolithic column . Anal. Chem. , 75 : 4904 – 4912 .
  • Hoth , D. C. , Rivera , J. G. and Colon , L. A. 2005 . Metal oxide monolithic columns . J. Chromatogr. A , 1079 : 392 – 396 .
  • Li , Y. , Chen , Y. , Xiang , R. , Ciuparu , D. , Pfefferle , L. D. , Horvath , C. and Wilkins , J. A. 2005 . Incorporation of single‐wall carbon nanotubes into an organic polymer monolithic stationary phase for µ‐HPLC and capillary electrochromatography . Anal. Chem. , 77 : 1398 – 1406 .
  • Leinweber , F. C. and Tallarek , U. 2003 . Chromatographic performance of monolithic and particulate stationary phases: Hydrodynamics and adsorption capacity . J. Chromatogr. A , 1006 : 207 – 228 .
  • Liu , Y. , Antonucci , V. , Shen , Y. , Vailaya , A. and Wu , N. 2005 . Practical applications of monolithic columns to pharmaceutical process development . J. Liq. Chromatogr. & Rel. Technol. , 28 : 361 – 376 .
  • Wu , N. , Dempsey , J. , Yehl , P. M. , Dovletoglou , A. , Ellison , D. K. and Wyvratt , J. M. 2004 . Practical aspects of fast HPLC separations for pharmaceutical process development using monolithic columns . Anal. Chim. Acta , 523 : 149 – 156 .
  • Kele , M. and Guichon , G. 1999 . Repeatability and reproducibility of retention data and band profiles on reversed‐phase liquid chromatography columns: I. Experimental protocol. II. Results obtained with Symmetry C18 columns . J. Chromatogr. A , 830 : 41 – 79 .
  • Siouffi , A. M. 2003 . Silica gel‐based monoliths prepared by the sol–gel method: facts and figures . Chromatogr. A , 1000 : 808 – 818 .
  • Gritti , F. and Guichon , G. 2004 . Heterogeneity of the surface energy on unused C18‐Chromolith adsorbents in reversed‐phase liquid chromatography . J. Chromatogr. A , 1028 : 105 – 119 .
  • Svec , F. , Peters , E. C. , Sykora , D. and Frechet , J. M.J. 2000 . Design of the monolithic polymers used in capillary electrochromatography columns . J. Chromatogr. A , 887 : 3 – 29 .
  • Tanaka , N. and Kobayashi , H. 2003 . Monolithic columns for liquid chromatography . Anal. Bioanal. Chem. , 376 : 298 – 301 .
  • Rieux , L. , Niederländer , H. , Verpoorte , E. and Bischoff , R. 2005 . Silica monolithic columns: Synthesis, characterisation and applications to the analysis of biological molecules . J. Sepn. Sci. , 28 : 1628 – 1641 .
  • Hsieh , Y. , Wang , G. , Wang , Y. , Chackalamannil , S. , Brisson , J. , Ng , K. and Korfmacher , W. A. 2002 . Simultaneous determination of a drug candidate and its metabolite in rat plasma samples using ultrafast monolithic column high‐performance liquid chromatography/tandem mass spectrometry . Rapid Commun. Mass Spectrom. , 16 : 944 – 950 .
  • Hsieh , Y. , Wang , G. , Wang , Y. , Chackalamannil , S. and Korfmacher , W. A. 2003 . Direct plasma analysis of drug compounds using monolithic column liquid chromatography and tandem mass spectrometry . Anal. Chem. , 75 : 1812 – 1818 .
  • Dear , G. , Plumb , R. and Mallet , D. 2001 . Use of monolithic silica columns to increase analytical throughput for metabolite identification by liquid chromatography/tandem mass spectrometry . Rapid Commun. Mass Spectrom. , 15 : 152 – 158 .
  • Kennedy , P. 2005 . Ultra‐fast amino acid analysis by LC‐TOF‐MS . LC•GC , : 24
  • Gerber , F. , Krummen , M. , Potgeter , H. , Roth , A. , Siffrin , Ch. and Spoendlin , Ch. 2004 . Practical aspects of fast reversed‐phase high‐performance liquid chromatography using 3 µm particle packed columns and monolithic columns in pharmaceutical development and production working under current good manufacturing practice . J. Chromatogr. A , 1036 : 127 – 133 .
  • Svec , F. and Frechet , J. M.J. 1992 . Continuous rods of macroporous polymer as high‐performance liquid chromatography separation media . Anal. Chem. , 64 : 820 – 2 .
  • Walcher , W. , Toll , H. , Ingendoh , A. and Huber , C. G. 2004 . Operational variables in high‐performance liquid chromatography–electrospray ionization mass spectrometry of peptides and proteins using poly(styrene–divinylbenzene) monoliths . J. Chromatogr. A , 1053 : 107 – 117 .
  • Pham‐Tuan , H. , Kaskavelis , L. , Daykin , C. A. and Janssen , H. 2003 . Method development in high‐performance liquid chromatography for high‐throughput profiling and metabonomic studies of biofluid samples . J. Chromatogr. B , 789 : 283 – 301 .
  • Hemmati , P. , Shilliam , C. S. , Hughes , Z. A. , Shah , A. J. , Roberts , J. C. , Atkins , A. R. , Hunter , A. J. and Heidbreder , C. A. 2001 . In vivo characterization of basal amino acid levels in subregions of the rat nucleus accumbens: effect of a dopamine D3/D2 agonist . Neurochem. Int. , 39 : 199 – 208 .
  • Hennessy , T. P. , Boysen , R. I. , Huber , M. I. , Unger , K. K. and Hearn , M. T.W. 2003 . Peptide mapping by reversed‐phase high‐performance liquid chromatography employing silica rod monoliths . J. Chromatogr. A , 1009 : 15 – 28 .
  • Xiong , L. , Zhang , R. and Regnier , F. E. 2004 . Potential of silica monolithic columns in peptide separations . J. Chromatogr. A , 1030 : 187 – 394 .
  • Minakuchi , H. , Nakanishi , K. , Soga , N. , Ishizuka , N. and Tanaka , N. 1996 . Octadecylsilylated porous silica rods as separation media for reversed‐phase liquid chromatography . Anal. Chem. , 68 : 3498 – 3501 .
  • Volmer , D. A. , Brombacher , S. and Whitehead , B. 2002 . Studies on azaspiracid biotoxins. I. Ultrafast high‐resolution liquid chromatography/mass spectrometry separations using monolithic columns . Rapid Commun. Mass Spectrom. , 16 : 2298 – 2305 .
  • Hatsis , P. and Lucy , C. A. 2002 . Ultra‐fast HPLC separation of common anions using a monolithic stationary phase . Analyst , 127 : 451 – 454 .
  • Koal , T. , Asperger , A. , Efer , J. and Engewald , W. 2003 . Simultaneous determination of a wide spectrum of pesticides in water by means of fast on‐line SPE‐HPLC‐MS‐MS‐a novel approach . Chromatographia , 57 ( Suppl. ) : S/93 – 101 .
  • Giddings , J. C. 1965 . Dynamics of Chromatography Part I. Principles and Theory 283 New York : Marcel Dekker .
  • Snyder , L. R. 1968 . Principles of Adsorption Chromatography 340 New York : Marcel Dekker .
  • Marin , S. J. , Jones , B. A. , Felix , W. D. and Clark , J. 2004 . Effect of high temperature on high‐performance liquid chromatography column stability and performance under temperature‐programmed conditions . J. Chromatogr. A , 1030 : 255 – 262 .
  • Nawrocki , J. , Dunlap , C. , Li , J. , Zhao , J. , McNeff , C. V. , McCormick , A. and Carr , P. W. 2004 . Part II. Chromatography using ultra‐stable metal oxide‐based stationary phases for HPLC . J. Chromatogr. A , 1028 : 31 – 62 .
  • Marin , S. J. , Jones , B. A. , Clark , J. , Lippert , A. J. , Johnson , T. M. , Leslie , B. and Ludlow , R. Silica based columns for high temperature HPLC . 227th ACS National Meeting, Anaheim . March 28–April 1 , CA, United States.
  • Cheng , Y.‐F. , Walter , T. H. , Lu , Z. , Iraneta , P. , Alden , B. A. , Gendreau , C. , Neue , U. D. , Grassi , J. M. , Carmody , J. L. , O'Gara , J. E. and Fisk , R. P. 2000 . Hybrid Organic–Inorganic Particle Technology: Breaking Through Traditional Barriers of HPLC Separations . LC · GC , : 1162 – 1172 .
  • Ross , P. and Knox , J. H. 1997 . Carbon‐based packing materials for liquid chromatography: applications . Adv. Chromatogr. , 37 : 121 – 162 .
  • Li , J. and Carr , P. W. 1997 . Effect of temperature on the thermodynamic properties, kinetic performance, and stability of polybutadiene‐coated zirconia . Anal. Chem. , 69 : 837 – 843 .
  • Li , J. , Hu , Y. and Carr , P. W. 1997 . Fast separations at elevated temperatures on polybutadiene‐coated zirconia reversed‐phase material . Anal. Chem. , 69 : 3884 – 3888 .
  • Wyndham , K. D. , O'Gara , J. E. , Walter , T. H. , Glose , K. H. , Lawrence , N. L. , Alden , B. A. , Izzo , G. S. , Hudalla , C. J. and Iraneta , P. C. 2003 . Characterization and Evaluation of C18 HPLC Stationary Phases Based on Ethyl‐Bridged Hybrid Organic/Inorganic Particles . Anal. Chem. , 75 : 6781 – 6788 .
  • Liu , Y. , Grinberg , N. , Thompson , K. C. , Wenslow , R. M. , Neue , U. D. , Morrison , D. , Walter , T. H. , O'Gara; , J. E. and Wyndham , K. D. Evaluation of a C18 hybrid stationary phase using high temperature chromatography . Anal. Chim. Acta , in press
  • Huhn , G. and Müller , H. 1993 . Polymer‐coated cation exchangers in high‐performance ion chromatography: preparation and application . J. Chromatogr. , 640 : 57
  • Zhu , P. L. , Snyder , L. R. , Dolan , J. W. , Djordjevic , N. M. , Hill , D. W. , Sander , L. C. and Waeghe , T. J. 1996 . Combined use of temperature and solvent strength in reversed‐phase gradient elution I. Predicting separation as a function of temperature and gradient conditions . J. Chromatgr. A , 756 : 21 – 39 .
  • Zhu , P. L. , Dolan , J. W. and Snyder , L. R. 1996 . Combined use of temperature and solvent strength in reversed‐phase gradient elution II. Comparing selectivity for different samples and systems . J. Chromatgr. A , 756 : 41 – 50 .
  • Zhu , P. L. , Dolan , J. W. , Snyder , L. R. , Hill , D. W. , Van Heukelem , L. and Waeghe , T. J. 1996 . Combined use of temperature and solvent strength in reversed‐phase gradient elution III. Selectivity for ionizable samples as a function of sample type and pH . J. Chromatgr. A , 756 : 51 – 62 .
  • Zhu , P. L. , Dolan , J. W. , Snyder , L. R. , Djordjevic , N. M. , Hill , D. W. , Lin , J.‐T. , Sander , L. C. and Van Heukelem , L. 1996 . Combined use of temperature and solvent strength in reversed‐phase gradient elution IV. Selectivity for neutral (non‐ionized) samples as a function of sample type and other separation conditions . Chromatgr. A , 756 : 63 – 72 .
  • Thompson , J. D. , Brown , J. S. and Carr , P. W. 2001 . Dependence of thermal mismatch broadening on column diameter in high speed liquid chromatography at elevated temperatures . Anal. Chem. , 73 : 3340 – 3347 .
  • Wu , N. , Tang , Q. , Lippert , A. J. and Lee , M. L. 2001 . Packed capillary column solvating gas chromatography using neat water mobile phase and flame ionization detection . J. Microcol. Sepn. , 13 : 41 – 47 .
  • Marin , S. J. , Jones , B. A. , Felix , W. D. and Clark , J. Feb. 26–Mar. 4 2005 . “ Improving speed and resolution of separation by utilizing high temperature and temperature programming in liquid chromatography. Pittcon 2005 ” . Feb. 26–Mar. 4 , Orlando, Florida
  • Trissel , L. A. 2000 . Handbook on Injectable Drugs Bethedsa, MD : American Society of Health‐System Pharmacists .
  • Xu , Q. A. and Trissel , L. A. 1999 . Stability‐Indicating HPLC Methods for Drug Analysis London : Pharmaceutical Press .
  • Connors , K. A. , Amidon , G. L. and Stella , V. J. 1986 . Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists New York : Wiley .
  • Rubinstein , M. H. 1989 . Pharmaceutical Technology‐Drug Stability Chichester : Halsted Press .
  • Huang , J. X. , Stuart , J. D. , Melander , W. R. and Horvath , Cs. 1984 . High‐performance liquid chromatography of substituted p‐benzoquinones and p‐hydroquinones: I. Interplay of on‐column redox reaction and the chromatographic retention process . J. Chromatogr. , 316 : 151 – 161 .
  • Jacobson , J. , Melander , W. , Vaisnys , G. and Horvath , Cs. 1984 . Kinetic study on cis‐trans proline isomerization by high‐performance liquid chromatography . J. Phys. Chem. , 88 : 4536 – 4542 .
  • Melander , W. R. , Lin , H.‐J. , Jacobson , J. and Horvath , Cs. 1984 . Dynamic effect of secondary equilibria in reversed‐phase chromatography . J. Phys. Chem. , 88 : 4527 – 4536 .
  • Thompson , J. D. and Carr , P. W. 2002 . A study of the critical criteria for analyte stability in high temperature liquid chromatography . Anal. Chem. , 74 : 1017 – 1023 .
  • Yan , B. , Zhao , J. , Brown , J. S. , Blackwell , J. and Carr , P. W. 2000 . High temperature ultrafast liquid chromatography . Anal. Chem. , 72 : 1253 – 1262 .
  • Ohbo , T. , Koizumi , H. , Tachibana , M. , Tani , K. and Kiba , N. 2002 . Organic compounds analysis by HPLC‐FID with high temperature water as a mobile phase . Chromatographia , 23 ( Suppl. ) : 25 – 26 .
  • Sanagi , M. M. , See , H. H. , Ibrahim , W. A.W. and Naim , A. A. 2005 . High temperature liquid chromatography of tocol‐derivatives on polybutadiene‐coated zirconia stationary phases . Chromatographia , 61 : 567 – 571 .
  • Yang , X. , Ma , L. and Carr , P. W. 2005 . High temperature fast chromatography of proteins using a silica‐based stationary phase with greatly enhanced low pH stability . J. Chromatogr. A , 1079 : 213 – 220 .
  • Stoll , D. R. and Carr , P. W. 2005 . Fast, Comprehensive two‐dimensional HPLC separation of tryptic peptides based on high temperature HPLC . J. Am. Chem. Soc. , 127 : 5034 – 5035 .
  • Clark , J. 2004 . Using high temperature HPLC for improved analysis . Pharm. Tech. Europe , 16 : 41 – 42 . 45 – 46 .
  • Thompson , J. D. and Carr , P. W. 2002 . High speed liquid chromatography by simultaneous optimization of temperature and eluent composition . Anal. Chem. , 74 : 4150 – 4159 .

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