131
Views
14
CrossRef citations to date
0
Altmetric
Original Articles

Rapid Quantitation of Digoxin in Human Plasma and Urine Using Isotope Dilution Liquid Chromatography‐Tandem Mass Spectrometry

, &
Pages 1917-1932 | Received 01 Dec 2005, Accepted 28 Dec 2005, Published online: 10 Nov 2011

References

  • Scherrmann , J. M. , Venet , R. , Menin , Y. and Bourdon , R. 1985 . Optimization of the dosage of digoxin: Proposition of a minimal exploratory protocol–optimisation de la posologie de la digoxine proposition d'un protocole exploratoire minimal . Therapie , 40 ( 2 ) : 73 – 79 .
  • Godfraind , T. 1989 . In Pharmacologie des Concepts Fondamentaux aux applications Thérapeutiques Edited by: Schorderet , M. 167 – 175 . Paris : Frisons‐Roche/Slatkine .
  • Stoll , R. G. , Christensen , M. S. , Sakmar , E. and Wagner , J. G. 1972 . The specificity of the digoxin radioimmunoassay procedure . Commun. Chem. Pathal. Pharmacol. , 4 : 503 – 510 .
  • Stone , J. A. and Soldin , S. J. 1989 . An update on digoxin . Clin. Chem. , 35 : 1326 – 1331 .
  • Baselt , R. C. and Cravey , R. H. 1995 . Disposition of toxic Drugs and chemicals in Man , 4th Ed. 802 – 810 . Foster City : Chemical Toxicology Institute .
  • Embree , L. and McErlane , K. M. 1990 . Comparison of digoxin analysis by high‐performance liquid chromatography/post‐column derivatization and fluorescence polarization immunoassay . Xenobiotica , 20 ( 6 ) : 635 – 643 .
  • Freytag , J. W. , Lau , H. P. and Wadsley , J. J. 1984 . Affinity‐column‐mediated immunoenzymometric assays: Influence of affinity‐column ligand and valency of antibody‐enzyme conjugates . Clin. Chem. , 30 ( 9 ) : 1494 – 1498 .
  • Reh , E. J. 1988 . Determination of digoxin in serum by on‐line immunoadsorptive clean‐up high‐performance liquid chromatographic separation and fluorescence‐reaction detection . Chromatogr. B , 43 : 119 – 130 .
  • Stone , J. A. and Soldin , S. J. 1988 . Improved liquid chromatographic/immunoassay of digoxin in serum . Clin. Chem. , 34 ( 12 ) : 2547 – 2551 .
  • Embree , L. and McErlane , K. M. 1989 . Development of a high‐performance liquid chromatographic‐post‐column fluorogenic assay for digoxin in serum . J. Chromatogr. B , 496 ( 2 ) : 321 – 334 .
  • Graefe , K. A. , Tang , Z. and Karnes , H. T. 2000 . High‐performance liquid chromatography with on‐line post‐column immunoreaction detection of digoxin and its metabolites based on fluorescence energy transfer in the far‐red spectral region . J. Chromatogr. B , 745 ( 2 ) : 305 – 314 .
  • Kwong , E. and McErlane , K. M. 1986 . Analysis of digoxin at therapeutic concentrations using high‐performance liquid chromatography with post‐column derivatization . J. Chromatogr. , 381 ( 2 ) : 357 – 363 .
  • Tzou , M. C. , Sams , R. A. and Reuning , R. H. 1995 . Specific and sensitive determination of digoxin and metabolites in human serum by high performance liquid chromatography with cyclodextrin solid‐phase extraction and precolumn fluorescence derivatization . j. Pharm. Biomed. Anal. , 13 ( 12 ) : 1531 – 1540 .
  • Tracqui , A. , Kintz , P. , Ludes , B. and Mangin , P. 1997 . High‐performance liquid chromatography‐ion spray mass spectrometry for the specific determination of digoxin and some related cardiac glycosides in human plasma . J. Chromatogr. B , 692 ( 1 ) : 101 – 109 .
  • Higashi , T. , Nakayama , N. , Shimada , K. , Kasai , H. and Nakazawa , H. 1999 . High‐performance liquid chromatography‐tandem mass spectrometry of cardiac steroids . J. Liq. Chromatogr. & Rel. Technol. , 22 ( 15 ) : 2283 – 2296 .
  • Arao , T. , Fuke , C. , Takaesu , H. , Nakamoto , M. , Morinaga , Y. and Miyazaki , T. 2002 . Simultaneous determination of cardenolides by sonic spray ionization liquid chromatography‐ion trap mass spectrometry—A fatal case of oleander poisoning . J. Anal. Toxicol. , 26 ( 4 ) : 222 – 227 .
  • Guan , F. , Ishii , A. , Seno , H. , Watanabe‐Suzuki , K. , Kumazawa , T. and Suzuki , O. 1999 . Identification and quantification of cardiac glycosides in blood and urine samples by HPLC/MS/MS . Anal. Chem. , 71 ( 18 ) : 4034 – 4043 .
  • Food and Drug Administration of the United States, Guidance for industry‐Bioanalytical Method Validation, US Department of Health and Human Services, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medecine (CVM), May 2001

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.