SIMULTANEOUS DETERMINATION OF DOXORUBICIN AND IRINOTECAN IN CONJUNCTION WITH THEIR MAJOR METABOLITES BY ULTRA HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

REFERENCES

• Sullivan , D. M. ; Latham , M. D. ; Ross , W. E. Proliferation-Dependent Topoisomerase II Content as a Determinant of Antineoplastic Drug Action in Human, Mouse, and Chinese Hamster Ovary Cells . Cancer research 1987 , 47 ( 15 ), 3973 – 3979 .
   PubMed Web of Science ®Google Scholar
• Minotti , G. ; Ronchi , R. ; Salvatorelli , E. ; Menna , P. ; Cairo , G. Doxorubicin Irreversibly Inactivates Iron Regulatory Proteins 1 and 2 in Cardiomyocytes: Evidence for Distinct Metabolic Pathways and Implications for Iron-Mediated Cardiotoxicity of Antitumor Therapy . Cancer research 2001 , 61 ( 23 ), 8422 – 8428 .
   PubMed Web of Science ®Google Scholar
• Takanashi , S. ; Bachur , N. R. Adriamycin Metabolism in Man. Evidence from Urinary Metabolites . Drug Metabol. Disposit. 1976 , 4 ( 1 ), 79 – 87 .
   PubMed Web of Science ®Google Scholar
• Santos , A. ; Zanetta , S. ; Cresteil , T. ; Deroussent , A. ; Pein , F. ; Raymond , E. ; Vernillet , L. ; Risse , M. L. ; Boige , V. ; Gouyette , A. ; Vassal , G. Metabolism of Irinotecan (Irinotecan) by CYP3A4 and CYP3A5 in Humans . Clin. Canc. Res. 2000 , 6 ( 5 ), 2012 – 2020 .
   PubMed Web of Science ®Google Scholar
• Katzenmeyer , J. B. ; Eddy , C. V. ; Arriaga , E. A. Tandem Laser-Induced Fluorescence and Mass Spectrometry Detection for High-Performance Liquid Chromatography Analysis of the In Vitro Metabolism of Doxorubicin . Anal. Chem. 2010 , 82 ( 19 ), 8113 – 8120 .
   PubMed Web of Science ®Google Scholar
• Maudens , K. E. ; Stove , C. P. ; Cocquyt , V. F. ; Denys , H. ; Lambert , W. E. Development and Validation of a Liquid Chromatographic Method for the Simultaneous Determination of Four Anthracyclines and Their Respective 13-S-Dihydro Metabolites in Plasma and Saliva . J. Chromatogr. B 2009 , 877 ( 30 ), 3907 – 3915 .
   PubMed Web of Science ®Google Scholar
• Maudens , K. E. ; Stove , C. P. ; Lambert , W. E. Optimization of a Liquid Chromatographic Separation for the Simultaneous Determination of Four Anthracyclines and Their Respective 13-S-Dihydro Metabolites . J. Sep. Sci. 2008 , 31 ( 6–7 ), 1042 – 1049 .
   PubMed Web of Science ®Google Scholar
• Gotlieb , W. H. ; Bruchim , I. ; Ben-Baruch , G. ; Davidson , B. ; Zeltser , A. ; Andersen , A. ; Olsen , H. Doxorubicin Levels in the Serum and Ascites of Patients with Ovarian Cancer . Eur. J. Surg. Oncol. 2007 , 33 ( 2 ), 213 – 215 .
   PubMed Web of Science ®Google Scholar
• Arnold , R. D. ; Slack , J. E. ; Straubinger , R. M. Quantification of Doxorubicin and Metabolites in Rat Plasma and Small Volume Tissue Samples by Liquid Chromatography/Electrospray Tandem Mass Spectroscopy . J. Chromatogr. B 2004 , 808 ( 2 ), 141 – 152 .
   PubMed Web of Science ®Google Scholar
• Bansal , T. ; Awasthi , A. ; Jaggi , M. ; Khar , R. K. ; Talegaonkar , S. Development and Validation of Reversed Phase Liquid Chromatographic Method Utilizing Ultraviolet Detection for Quantification of Irinotecan (Irinotecan) and Its Active Metabolite, SN-38, in Rat Plasma and Bile Samples: Application to Pharmacokinetic Studies. Talanta 2008, 76 (5), 1015–1021.
   PubMed Web of Science ®Google Scholar
• Hu , Z. P. ; Yang , X. X. ; Chen , X. ; Chan , E. ; Duan , W. ; Zhou , S. F. Simultaneous Determination of Irinotecan (Irinotecan) and SN-38 in Tissue Culture Media and Cancer Cells by High Performance Liquid Chromatography: Application to Cellular Metabolism and Accumulation Studies . J. Chromatogr. B 2007 , 850 ( 1–2 ), 575 – 580 .
   PubMed Web of Science ®Google Scholar
• Yang , X. ; Hu , Z. ; Chan , S. Y. ; Goh , B. C. ; Duan , W. ; Chan , E. ; Zhou , S. Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (Irinotecan) and Its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat . J. Chromatogr. B 2005 , 821 ( 2 ), 221 – 228 .
   PubMed Web of Science ®Google Scholar
• Bardin , S. ; Guo , W. ; Johnson , J. L. ; Khan , S. ; Ahmad , A. ; Duggan , J. X. ; Ayoub , J. ; Ahmad , I. Liquid Chromatographic-Tandem Mass Spectrometric Assay for the Simultaneous Quantification of Camptosar and Its Metabolite SN-38 in Mouse Plasma and Tissues . J. Chromatogr. A 2005 , 1073 ( 1–2 ), 249 – 255 .
   PubMed Web of Science ®Google Scholar
• Poujol , S. ; Pinguet , F. ; Malosse , F. ; Astre , C. ; Ychou , M. ; Culine , S. ; Bressolle , F. Sensitive HPLC-Fluorescence Method for Irinotecan and Four Major Metabolites in Human Plasma and Saliva: Application to Pharmacokinetic Studies . Clin. Chem. 2003 , 49 ( 11 ), 1900 – 1908 .
   PubMed Web of Science ®Google Scholar
• Schoemaker , N. E. ; Rosing , H. ; Jansen , S. ; Schellens , J. H. ; Beijnen , J. H. High-Performance Liquid Chromatographic Analysis of the Anticancer Drug Irinotecan (Irinotecan) and Its Active Metabolite SN-38 in Human Plasma . Therapeut. Drug Monitor. 2003 , 25 ( 1 ), 120 – 124 .
   PubMed Web of Science ®Google Scholar
• Sparreboom , A. ; de Bruijn , P. ; de Jonge , M. J. ; Loos , W. J. ; Stoter , G. ; Verweij , J. ; Nooter , K. Liquid Chromatographic Determination of Irinotecan and Three Major Metabolites in Human Plasma, Urine and Feces . J. Chromatogr. B 1998 , 712 ( 1–2 ), 225 – 235 .
   PubMed Web of Science ®Google Scholar
• Rothenberg , M. L. Irinotecan (Irinotecan): Recent Developments and Future Directions--Colorectal Cancer and Beyond . Oncolog. 2001 , 6 ( 1 ), 66 – 80 .
   Web of Science ®Google Scholar
• Nishimura , S. ; Tsuda , H. ; Hashiguchi , Y. ; Kokawa , K. ; Nishimura , R. ; Ishiko , O. ; Kamiura , S. ; Hasegawa , K. ; Umesaki , N. Phase II Study of Irinotecan Plus Doxorubicin for Early Recurrent or Platinum-Refractory Ovarian Cancer: Interim Analysis . Int. J. Gynecolog. Canc. 2007 , 17 ( 1 ), 159 – 163 .
   PubMed Web of Science ®Google Scholar
• Morgensztern , D. ; Baggstrom , M. Q. ; Pillot , G. ; Tan , B. ; Fracasso , P. ; Suresh , R. ; Wildi , J. ; Govindan , R. A Phase I Study of Pegylated Liposomal Doxorubicin and Irinotecan in Patients with Solid Tumors . Chemotherapy 2009 , 55 ( 6 ), 441 – 445 .
   PubMed Web of Science ®Google Scholar
• Xenidis , N. ; Vardakis , N. ; Varthalitis , I. ; Giassas , S. ; Kontopodis , E. ; Ziras , N. ; Gioulbasanis , I. ; Samonis , G. ; Kalbakis , K. ; Georgoulias , V. Alpha Multicenter Phase II Study of Pegylated Liposomal Doxorubicin in Combination with Irinotecan as Second-Line Treatment of Patients with Refractory Small-Cell Lung Cancer . Canc. Chemother. Pharmacol. 2011 , 68 ( 1 ), 63 – 68 .
   PubMed Web of Science ®Google Scholar
• Reszka , K. J. ; Wagner , B. A. ; Teesch , L. M. ; Britigan , B. E. ; Spitz , D. R. ; Burns , C. P. Inactivation of Anthracyclines by Cellular Peroxidase . Canc. Res. 2005 , 65 ( 14 ), 6346 – 6353 .
   PubMed Web of Science ®Google Scholar