262
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY OF THYMOQUINONE IN RABBIT PLASMA AND ITS APPLICATION TO PHARMACOKINETICS

, , &
Pages 2242-2250 | Published online: 18 Jun 2013

REFERENCES

  • Padhye , S. ; Banerjee , S. ; Ahmad , A. ; Mohammad , R. ; Sarkar , F. H. From Here to Eternity- the Secret of Pharaohs: Therapeutic Potential of Black Cumin Seeds and Beyond . Cancer. Therapeut. 2008 , 6 , 495 – 510 .
  • Jansen , P. C. M. Spices, Condiments and Medicinal Plants in Ethiopia, their Taxonomy and Agricultural Significance, Center for Agricultural Publishing and Documentation: Addis Ababa, 1981; pp 76–85.
  • Chopra , R. N. ; Nayar , S. L. ; Chopra , I. C. Glossary of Indian Medicinal Plants , CSIR : New Delhi , 1956 ; 175 .
  • Nadkarni , K. Crocus sativus, Nigella sativa . In Indian Material Medica ; Nadkarni , K. M. , Ed.; Popular Prakashan : Bombay , 1976 ; pp 386 – 411 .
  • Mahfouz , M. ; Abdel Maguid , R. ; El-Dakhakhny , M. Effectiveness of Nigellone in Asthma in Adults . Alex. Med. J. 1960 , 6 , 543 – 547 .
  • Hashem , F. M. ; El-Kiey , M. A. Nigella sativa Seeds of Egypt. J. Pharm. Sci. United Arab Repub. 1982 , 3 , 121 – 133 .
  • Enomoto , S. ; Asano , R. ; Iwahori , Y. ; Narui , T. ; Okada , Y. ; Singab , A. N. ; Okuyama , T. Hematological Studies on Black Cumin Oil from the Seeds of Nigella sativa L . Biol. Pharm. Bull. 2001 , 24 , 307 – 310 .
  • Hassan , M. ; El-Dakhakhny , M. Effect of Some Nigella sativa Constituents on Chemical Carcinogenesis in Hamster Cheek Pouch . J. Egypt. Soc. Pharma. Exper. Therap. 1992 , 11 , 675 – 677 .
  • Worthen , D. ; Ghosheh , O. ; Crooks , P. The in vitro Anti-Tumor Activity of Some Crude and Purified Components of Black Seed, Nigella sativa L . Anticancer Res. 1998 , 18 , 1527 – 1532 .
  • El-Dakhakhny , M. Studies on the Egyptian Nigella sativa L. IV Some Pharmacological Properties of Seeds Active Principle in Comparison to its Dihydro Compound and its Polymer . Arzneim Forsch, Drug. Res. 1965 , 15 , 1227 – 1229 .
  • Mansour , M. A. ; Nagi , M. N. ; El-Khatib , A. S. ; Al-Bekairi , A. M. Effects of Thymoquinone on Antioxidant Enzyme Activities, Lipid Peroxidation and DT-Diaphorase in Different Tissues of Mice: A Possible Mechanism of Action . Cell. Biochem. Funct. 2002 , 20 , 143 – 151 .
  • Chakravarty , N. Inhibition of Histamine Release from Mast Cells by Nigellone . Ann. Allergy 1993 , 70 , 237 – 242 .
  • Houghton , P. J. ; Zarka , R. ; De las Heras , B. ; Hoult , R. S. Fixed Oil of Nigella sativa and Derived Thymoquinone Inhibit Eicosanoid Generation in Leukocytes and Membrane Lipid Peroxidation . Planta. Med. 1995 , 61 , 33 – 36 .
  • Akhtar , M. S. ; Riffat , S. Field Trial of Saussurea lappa Roots against Nematodes and Nigella sativa Seeds against Cestodes in Children . J. Pak. Med. Assoc. 1991 , 41 , 185 – 187 .
  • Agarwal , R. ; Kharya , M. D. ; Shrivastava , R. Antimicrobial and Anthelminthic Activities of the Essential Oil of Nigella sativa Linn . Ind. J. Exp. Biol. 1979 , 17 , 1264 – 1265 .
  • Mahmoud , M. R. ; El-Abhar , H. S. ; Saleh , S. The Effect of Nigella sativa Oil against the Liver Damage Induced by Schistosoma mansoni Infection in Mice . J. Ethnopharmacol. 2002 , 79 , 1 – 11 .
  • Salem , M. L. ; Hossain , M. S. Protective Effect of Black Seed Oil from Nigella sativa against Murine Cytomegalovirus Infection . Int. J. Immunopharmacol. 2000 , 22 ( 9 ), 729 – 740 .
  • Hanafy , M. S. ; Hatem , M. E. Studies on the Antimicrobial Activity of Nigella sativa Seed (Black Cumin) . J. Ethnopharmacol. 1991 , 34 , 275 – 278 .
  • Aboul Ela , M. A. ; El-Shaer , N. S. ; Ghanem , N. B. Antimicrobial Evaluation and Chromatographic Analysis of Some Essential and Fixed Oils . Pharmazie 1996 , 51 , 993 – 994 .
  • Zaoui , A. ; Cherrah , Y. ; Lacaille-Dubois , M. A. ; Settaf , A. ; Amarouch , H. ; Hassar , M. Diuretic and Hypotensive Effects of Nigella sativa in the Spontaneously Hypertensive Rat . Therapie 2000 , 5 , 379 – 382 .
  • Daba , M. H. ; Abdel-Rahman , M. S. Hepatoprotective Activity of Thymoquinone in Isolated Rat Hepatocytes . Toxicol. Lett. 1998 , 16 , 23 – 29 .
  • Swamy , S. M. ; Tan , B. K. Cytotoxic and Immunopotentiating Effects of Ethanolic Extract of Nigella sativa L Seeds . J. Ethnopharmacol. 2000 , 70 , 1 – 7 .
  • Alkharfy , K. M. ; Al-Daghri , N. M. ; Al-Attas , O. S. ; Alokail , M. S. The Protective Effect of Thymoquinone against Sepsis Syndrome Morbidity and Mortality in Mice . Int. Immunopharmacol. 2011 , 11 ( 2 ), 250 – 254 .
  • Pathan , S. A. ; Jain , G. K. ; Zaidi , S. M. A. ; Akhter , S. ; Vohora , D. ; Chander , P. ; Kole , P. L. ; Ahmad , F. J. ; Khar , R. K. Stability-indicating Ultra-Performance Liquid Chromatography Method for the Estimation of Thymoquinone and its Application in Biopharmaceutical Studies . Biomed Chromatogr. 2011 , 25 , 613 – 620 .
  • Amini , M. ; Khanavi , M. ; Shafiee , A. Simple High-Performance Liquid Chromatographic Method for Determination of Ciprofloxacin in Human Plasma . Iran. J. Pharm. Res. 2004 , 2 , 99 – 101 .
  • Marten , T. R. ; Ruane , R. J. Drug Metabolism Studies using HPLC . Chromatographia 1980 , 13 , 137 – 140 .
  • Afshin , Z. ; Alireza , S. ; Seyed , M. F. ; Hooman , M. Rapid Quantification of Valsartan in Human Plasma by Liquid Chromatography using a Monolithic Column and a Fluorescence Detection: Application for Pharmacokinetic Studies . Sci. Pharm. 2008 , 76 , 439 – 450 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.