Stability Indicating RP-HPLC Studies for the Estimation of Irbesartan and Amlodipine Besylate in Pharmaceutical Formulations and Identification and Characterization of Degradants Using LC-MS

References

• Johnston , C. I. Pharmacology of Irbesartan . Expert Opin. Invest. Drugs 1999 , 8 , 655 – 670 .
   PubMedGoogle Scholar
• Lewis , E. J. ; Hunsicker , L. G. ; Clarke , W. R. ; Berl , T. ; Pohl , M. A. Collaborative Study Group: Renoprotective Effect of the Angiotensin-Receptor Antagonist irbesartan in Patients with Nephropathy Due to Type 2 Diabetes . N. Engl. J. Med. 2001 , 345 , 851 – 860 .
   PubMed Web of Science ®Google Scholar
• Abernethy , D. R. The Pharmacokinetics Profile of Amlodipine . Am. Heart J. 1989 , 118 , 1100 – 1103 .
   PubMed Web of Science ®Google Scholar
• Kungys , G. ; Naujoks , H. ; Wanner , C. Pharmacokinetics of Amlodipine in Hypertensive Patients Undergoing Haemodialysis . Eur. J. Clin. Pharmacol. 2003 , 59 , 291 – 295 .
   PubMed Web of Science ®Google Scholar
• Reid , J. L. ; Meredith , P. A. ; Donnelly , R. ; Elliot , H. L. Pharmacokinetics of Calcium Antagonists . J. Cardiovasc. Pharmacol. 1988 , 12 , S22 – S26 .
   PubMed Web of Science ®Google Scholar
• Chihiro , S. ; Tetsuaki , S. ; Nobuaki , K. ; Akira , K. ; Shingo , S. ; Hisayoshi , O. ; Akihiro , N. ; Nobuakira , T. Beneficial Effect of Combination Therapy with Antihypertensive Drugs in Patients with Hypertension . Exp. Clin. Cardiol. 2007 , 12 , 33 – 36 .
   PubMedGoogle Scholar
• Garnock-Jones , K. P. Irbesartan/Amlodipine: A Review of Its Use in Adult Patients with Essential Hypertension Not Adequately Controlled with Monotherapy . Am. J. Cardiovasc. Drugs 2013 , 13 , 141 – 150 .
   PubMed Web of Science ®Google Scholar
• Prashanthi , R. ; Raghavi , K. ; Sindhura , M. ; Anupama , B. ; Nalluri , B. N. Development and Validation of a Sensitive RP-HPLC-PDA Method for Assay of irbesartan in Pure and Pharmaceutical Dosage Forms . Int. J. Pharm. Bio Sci. 2012 , 3 , 397 – 406 .
   Google Scholar
• Sujana , K. ; Gowri Shankar , D. RP-HPLC-DAD Method for Determination of irbesartan in Bulk and Tablets Exposed to Forced Conditions . Int. J. Pharm. Res. Dev. 2011 , 3 , 67 – 73 .
   Google Scholar
• Raju , R. R. ; Babu , N. B. Development and Validation of HPLC Method for the Estimation of Irbesartan in Pharmaceutical Dosage Form . Pharmacophore 2011 , 2 , 145 – 149 .
   Google Scholar
• Avadhanulu , A. B. ; Srinivas , J. S. ; Anjaneyulu , A. RP-HPLC Estimation of Amlodipine Besylate in Drug and Pharmaceutical Formulations . Indian Drugs 1996 , 33 , 36 – 38 .
   Google Scholar
• Rajeswari , K. R. ; Sankar , G. G. ; Rao , A. L. ; Sheshagirirao , J. V. RP-HPLC Method for Simultaneous Determination of Atorvastatin Calcium and Amlodipine in Tablet . Indian J. Pharm. Sci. 2006 , 68 , 275 – 277 .
   Google Scholar
• Chitlange , S. S. ; Imran , M. ; Sakarkar , D. M. RP-HPLC Method for Simultaneous Estimation of Amlodipine and Metoprolol in Tablet Formulation . Asian J. pharm. 2008 , 2 , 232 – 234 .
   Google Scholar
• Patil , A. E. ; Devtalu , S. V. ; Patil , N. D. ; Patil , S. V. ; Bari , M. M. ; Barhate , S. D. Validated RP-HPLC Method for Simultaneous Estimation of Amlodipine Besylate and Clopidogrel Bisulphate in Bulk and Tablet Dosage Form . Int. J. Bioanal. 2013 , 2 , 412 – 415 .
   Google Scholar
• Shah , D. A. ; Bhatt , K. K. ; Mehta , R. S. ; Baldania , S. L. ; Gandhi , T. R. Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations . Indian J. Pharm. Sci. 2008 , 70 , 754 – 760 .
   PubMed Web of Science ®Google Scholar
• Color versions of one or more of the figures in the article can be found online at www.tandfonline.com/ljlc.
   Google Scholar