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Original Articles

ASSESSMENT OF LIPOPHILICITY OF SOME BIOLOGICALLY ACTIVE ARYLPIPERAZINES BY RPTLC AND MULTIVARIATE ANALYSIS

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REFERENCES

  • Gleeson , M. P. ; Hersey , A. ; Montanari , D. ; Overington , J. Probing the Links Between In Vitro Potency, ADMET and Physicochemical Parameters . Nat. Rev. Drug Discovery 2011 , 10 , 197 – 208 .
  • Liu , T. ; Nicholls , I. A. ; Öberg , T. Comparison of Theoretical and Experimental Models for Characterizing Solvent Properties Using Reversed Phase Liquid Chromatography . Anal. Chim. Acta 2011 , 702 , 37 – 44 .
  • Quiñones-Torrelo , C. ; Sagrado , S. ; Villanueva-Camañas , R. M. ; Medina-Hernández , M. J. Role of Hydrophobicity on the Monoamine Receptor Binding Affinities of Central Nervous System Drugs: A Quantitative Retention–Activity Relationships Analysis Using Biopartitioning Micellar Chromatography . J. Chromatogr. B 2004 , 801 , 185 – 198 .
  • Soczewinski , E. ; Matysik , G. Two Types of RM-Composition Relationships in Liquid–Liquid Partition Chromatography . J. Chromatogr. 1968 , 32 , 458 – 471 .
  • Kaliszan , R. Structure and Retention in Chromatography. A Chemometric Approach , Harwood Academic Publishers : Amsterdam , 1997 .
  • Casoni , D. ; Kot-Wasik , A. ; Namiesnik , J. ; Sârbu , C. Lipophilicity Data for Some Preservatives Estimated by Reversed-Phase Liquid Chromatography and Different Computation Methods . Chromatographia 2009 , 70 ( 7 ), 1277 – 1282 .
  • Koba , M. ; Bączek , T. ; Marszałł , M. P. Importance of Retention Data from Affinity and Reverse-Phase High-Performance Liquid Chromatography on Antitumor Activity Prediction of Imidazoacridinones Using QSAR Strategy . J. Pharm. Biomed. Anal. 2012 , 64–65 , 87 – 93 .
  • Šegan , S. ; Trifković , J. ; Verbić , T. ; Opsenica , D. ; Zlatović , M. ; Burnett , J. ; Šolaja , B. ; Milojković-Opsenica , D. Correlation Between Structure, Retention, Property, and Activity of Biologically Relevant 1,7-Bis(aminoalkyl)diazachrysene Derivatives . J. Pharm. Biomed. Anal. 2013 , 72 , 231 – 239 .
  • Rabtti , E. H. M. A. ; Natić , M. M. ; Milojković-Opsenica , D. M. ; Trifković , J. Đ. ; Vučković , I. M. ; Vajs , V. E. ; Tešić , Ž. Lj. RP TLC-Based Lipophilicity Assessment of Some Natural and Synthetic Coumarins . J. Braz. Chem. Soc. 2012 , 23 , 522 – 530 .
  • Rabtti , E. H. M. A. ; Natić , M. M. ; Milojković-Opsenica , D. M. ; Trifković , J. Đ. ; Tosti , T. ; Vučković , I. M. ; Vajs , V. ; Tešić , Ž. L. J. Quantitative Structure-Toxicity Relationship Study of Some Natural and Synthetic Coumarins Using Retention Parameters . J. Serb. Chem. Soc. 2012 , 77 , 1443 – 1456 .
  • Trifković , J. ; Andrić , F. ; Ristivojević , P. ; Andrić , D. ; Tesić , Ž. Lj. ; Milojković-Opsenica , D. M. Structure-Retention Relationship Study of Arylpiperazines by Linear Multivariate Modeling . J. Sep. Sci. 2010 , 33 , 2619 – 2628 .
  • Šukalović , V. ; Ignjatović , Dj. ; Tovilović , G. ; Andrić , D. ; Shakib , K. ; Kostić-Rajačić , S. ; Šoškić , V. Interactions of N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-2-aryl-2-ylacetamides and 1-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-3-aryl-2-ylureas with Dopamine D2 and 5-Hydroxytryptamine 5HT1A Receptors . Bioorg. Med. Chem. Lett. 2012 , 22 , 3967 – 3972 .
  • Horváth , C. ; Melander , W. ; Molnar , I. Solvophobic Interactions in Liquid Chromatography with Nonpolar Stationary Phases . J. Chromatogr. 1976 , 125 , 129 – 156 .
  • Thakur , M. ; Thakur , A. ; Khadikarc , P. V. ; Supurand , C. T. QSAR Study on pKa vis-à-vis Physiological Activity of Sulfonamides: A Dominating Role of Surface Tension (Inverse Steric Parameter) . Bioorg. Med. Chem. Lett. 2005 , 15 , 203 – 209 .
  • Vailaya , A. ; Horvath , C. Retention in Reversed-Phase Chromatography: Partition or Adsorption? J. Chromatogr. A 1998 , 829 , 1 – 27 .
  • Šegan , S. ; Andrić , F. ; Radoičić , A. ; Opsenica , D. ; Šolaja , B. ; Zlatović , M. ; Milojković-Opsenica , D. Correlation Between Structure, Retention and Activity of Cholic Acid Derived Cis–Trans Isomeric Bis-Steroidal Tetraoxanes . J. Sep. Sci. 2011 , 34 , 2659 – 2667 .

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