Study on Characterization of the Degradation Products and Dynamics of Valtrate in the Artificial Gastrointestinal Fluid by HPLC- ESI MS/MSⁿ

References

• Backlund , A. ; Moritz , T. Phylogenetic Implications of an Expanded Valepotriate Distribution in the Valerianaceae . Biochem. Syst. Ecol. 1998 , 26 , 309 – 335 .
   Web of Science ®Google Scholar
• Bos , R. ; Woerdenbag , H. J. ; Pras , N. Determination of Valepotriates . J. Chromatogr. A. 2002 , 967 , 131 – 146 .
   PubMed Web of Science ®Google Scholar
• Rather , A. M. ; Nawcho , I. A. ; Ganie , A. H. ; Singh , H. ; Dutt , B. ; Wani , A. A. Bioactive Compounds & Medicinal Properties of Valeriana jatamansi Jones – A Review . Life Sci. J. 2012 , 9 , 847 – 850 .
   Google Scholar
• Wagner , H. ; Jurcic , K. On the Spasmolytic Activity of Valeriana Extracts . Planta Med. 1979 , 37 , 84 – 87 .
   PubMed Web of Science ®Google Scholar
• Lin , S. ; Shen , Y. H. ; Li , H. L. ; Yang , X. W. ; Chen , T. ; Lu , L. H. ; Zhang , Z. S. ; Liu , R. H. ; Xu , X. K. ; Zhang , W. D. ; Wang , H. Acylated Iridoids with Cytotoxicity from Valeriana jatamansi. Nat. Prod . 2009 , 72 , 650 – 655 .
   PubMed Web of Science ®Google Scholar
• Fuzzati , N. ; Wolfender , J. L. ; Hostettmann , K. ; Msonthi , J. D. ; Mavi , S. ; Mollleyres , L. P. Isolation of Antifungal Valepotriates from Valeriana capense and the Search for Valepotriates in Crude Valerianaceae Extracts . Phytochem. Anal. 1996 , 7 , 76 – 85 .
   Web of Science ®Google Scholar
• Tamura , S. ; Shimizu , N. ; Fujiwara , K. ; Kaneko , M. ; Kimura , T. ; Murkami , N. Bioisostere of Valtrate, Anti-HIV Principle by Inhibition for Nuclear Export of Rev . Bioorg. Med. Chem. Lett. 2010 , 20 , 2159 – 2162 .
   PubMed Web of Science ®Google Scholar
• Tamura , S. ; Fujiwara , K. ; Shimizu , N. ; Todo , S. ; Murkami , N. Concise Synthesis of 5,6-Dihydrovaltrate Leading to Enhanced Rev-Export Inhibitory Congener . Bioorg. Med. Chem. 2010 , 18 , 5975 – 5980 .
   PubMed Web of Science ®Google Scholar
• Bounthanh , C. ; Bergmann , C. ; Beck , J. P. ; Haag-Berrurier , M. ; Anton , R. Valepotriates, A New Class of Cytotoxic and Antitumor Agents . Planta Med. 1981 , 41 , 21 – 28 .
   PubMed Web of Science ®Google Scholar
• Bos , R. ; Woerdenbag , H. J. ; Hendriks , H. ; Zwaving , J. H. ; De Smet , P. A. G. M. ; Tittel , G. ; Wikstrom , H. V. ; Scheffer , J. J. C. Analytical Aspects of Phytotherapeutic Valerian Preparations . Phytochem. Anal. 1996 , 7 , 143 – 151 .
   Web of Science ®Google Scholar
• Bas , R. ; Hendriks , H. Cytotoxic Potential of Valerian Constituents and Valerian Tinctures . Phytomedicine 1998 , 5 , 219 – 225 .
   PubMed Web of Science ®Google Scholar
• Wagner , H. ; Jurcic , K. ; Schaette , R. ; Vergleichende Untersuchungen uber die sedierende Wirkung von Baldrianextrakten Valepotriaten und ihren Abbauprodukten . Planta Med. 1980 , 38 , 358 – 365 .
   Web of Science ®Google Scholar
• Wang , C. G. ; Liu , Y. ; Shi , J. ; Xiao , Y. ; Shi , S. N. ; Hou , W. H. ; Wang , Z. J. Study on the Mass Spectrum Characterization of Five Valepotriates by Electrospray Ionization Tandem Mass Spectrometry . Chin. J. Chin. Mater. Med. 2013 , 38 , 578 – 584 .
   Google Scholar
• Chen , Y. G. ; Yu , L. L. ; Huang , R. ; Lv , Y. P. ; Gui , S. H. 11-Methoxyviburtinal, A New Iridod from Valeriana jatamansi. Arch. Pham. Res . 2005 , 28 , 1161 – 1163 .
   PubMed Web of Science ®Google Scholar
• Levine , I. N. Physical Chemistry , McGraw-Hill, Inc. : New York , 2008 .
   Google Scholar
• Veith , J. ; Schneider , G. ; Lmmer , B. ; Wilems , M. The Influence of some Degradation Products of Valepotriates on the Motor Activity of Light-Dark Synchronized Mice . Planta Med. 1986 , 52 , 179 – 183 .
   Google Scholar
• Braun , R. ; Dieckmann , H. ; Machut , M. ; Echarti , C. ; Maurer , H. R. The Effect of Baldrinal on Hematoipoetic Cells In Vitro, on the Metabolic Activity of the Liver In Vivo and on Its Analysis in Proprietary Drugs . Planta Med. 1986 , 6 , 446 – 450 .
   PubMed Web of Science ®Google Scholar
• Wang , C. G. ; Liu , Y. ; Hou , W. H. ; Shi , S. N. ; Shi , J. L. Study on Characterization of the Degradation Products of Valtrate in Oxidation Condition and Its Oxidation Kinetics by HPLC-ESI MS/MS . J. Intrum. Anal. 2013 , 32 , 442 – 447 .
   Google Scholar
• Color versions of one or more of the figures in the article can be found online at www.tandfonline.com/ljlc.
   Google Scholar