Optimization of Extraction Methods for Flavonoids in Onion by RP-HPLC–DAD

References

• Prakash, D.; Singh, B. N.; Upadhyay, G. Antioxidant and Free Radical Scavenging Activities of Phenols from Onion (Allium cepa). Food Chem. 2007, 102, 1389–1393.
   Web of Science ®Google Scholar
• Roldán, E.; Sánchez-Moreno, C.; de Ancos, B.; Cano, M. P. Characterization of Onion (Allium cepa L.) By-Products as Food Ingredients with Antioxidant and Antibrowning Properties. Food Chem. 2008, 108, 907–916.
   PubMed Web of Science ®Google Scholar
• Griffiths, G.; Trueman, L.; Crowther, T.; Thomas, B.; Smith, B. Onions-A Global Benefit to Health. Phytother. Res. 2002, 16, 603–615.
   PubMed Web of Science ®Google Scholar
• Scalbert, A.; Manach, A. C.; Morand, C.; Remesy, C.; Jimenez, L. Dietary Polyphenols and the Prevention of Diseases. Crit. Rev. Food Sci. Nutr. 2005, 45, 287–306.
   PubMed Web of Science ®Google Scholar
• Hertog, M. G. L.; Hollman, P. C. H.; Katan, M. B. Content of Potentially Anticarcinogenic Flavonoids of 28 Vegetables and 9 Fruits Commonly Consumed in the Netherlands. J. Agric. Food. Chem. 1992, 40, 2379–2383.
   Web of Science ®Google Scholar
• Wach, A.; Pyrzynska, K.; Biesaga, M. Quercetin Content in Some Food and Herbal Samples. Food Chem. 2007, 100, 699–704.
   Web of Science ®Google Scholar
• Slimestad, R.; Fossen, T.; Vagen, I. M. Onions: A Source of Unique Dietary Flavonoids. J. Agric. Food Chem. 2007, 55, 10067–10080.
   PubMed Web of Science ®Google Scholar
• Vinson, J. A.; Dabbagh, Y. A.; Serry, M. M.; Jang, J. Plant Flavonoids, Especially Tea Flavonols, are Powerful Antioxidants Using an In Vitro Oxidation Model for Heart Disease. J. Agric. Food Chem. 1995, 43, 2800–2804.
   Web of Science ®Google Scholar
• Hollman, P. C. H.; Van Trijp, J. M. P.; Buysman, M. N. C. P.; Gaag, M. S. v. d.; Mengelers, M. J. B.; De Vries, J. H. M.; Katan, M. B. Relative Bioavailability of the Antioxidant Flavonoid Quercetin from Various Foods in Man. FEBS Lett. 1997, 418, 152–156.
   PubMed Web of Science ®Google Scholar
• Larson, R. L. The Antioxidants of Higher Plants. Phytochemistry. 1988, 4, 969–978.
   Web of Science ®Google Scholar
• Lu, X.; Ross, C. F.; Powers, J. R.; Rasco, B. A. Determination of Quercetins in Onion (Allium cepa) Using Infrared Spectroscopy. J. Agric. Food Chem. 2011, 59, 6376–6382.
   PubMed Web of Science ®Google Scholar
• International Conference on Harmonization (ICH). Validation of Analytical Procedures: Methodology, Q2B (CPMP/ICH/281/95); IFPMA: Geneva, 1995.
   Google Scholar
• Paola, R.; Arabbi, M. I. G.; Franco, M. L. Flavonoids in Vegetable Foods Commonly Consumed in Brazil and Estimated Ingestion by the Brazilian Population. J. Agric. Food Chem. 2004, 52, 1124–1131.
   PubMed Web of Science ®Google Scholar
• Beesk, N.; Perner, H.; Schwarz, D.; George, E.; Kroh, L. W.; Rohn, S. Distribution of Quercetin-3,40-O-Diglucoside, Quercetin-40-O-Monoglucoside, and Quercetin in Different Parts of the Onion Bulb (Allium cepa L.) Influenced by Genotype. Food Chem. 2010, 122, 566–571.
   Web of Science ®Google Scholar
• Yoo, K. S.; Lee, E. J.; Patil, Bhimanagouda. S. Quantification of Quercetin Glycosides in 6 Onion Cultivars and Comparisons of Hydrolysis-HPLC and Spectrophotometric Methods in Measuring Total Quercetin Concentrations. J. Food Sci. 2010, 75, 160–165.
   PubMed Web of Science ®Google Scholar
• Lombard, K. A.; Geofriau, E.; Pefey, E. Flavonoid Quantification in Onion by Spectrophotometric and High Performance Liquid Chromatography. HortScience. 2002, 37, 682–685.
   Web of Science ®Google Scholar
• Sellappan, S.; Akoh, C. C. Flavonoids and Antioxidant Capacity of Georgia-Grown Vidalia Onions. J. Agric. Food Chem. 2002, 50, 5338–5342.
   PubMed Web of Science ®Google Scholar
• Søltoft, M.; Nielsen, J.; Holst Laursen, K.; Husted, S.; Halekoh, U.; Knuthsen, P. Effects of Organic and Conventional Growth Systems on the Content of Flavonoids in Onions and Phenolic Acids in Carrots and Potatoes. J. Agric. Food Chem. 2010, 58, 10323–10329.
   PubMed Web of Science ®Google Scholar
• Olsson, M. E.; Gustavsson, K. E.; Vagen, I. M. Quercetin and Isorhamnetin in Sweet and Red Cultivars of Onion (Allium cepa L.) at Harvest, After field Curing, Heat Treatment, and Storage. J. Agric. Food Chem. 2010, 58, 2323–2330.
   PubMed Web of Science ®Google Scholar