Different Chromatographic and Electrophoretic Methods for Analysis of Proton Pump Inhibitors (PPIs): A Review

References

• Patrick, G. L. An Introduction to Medicinal Chemistry, 4th Ed.; New York, 2009; Ch. 25, 653–680.
   Google Scholar
• http:/www.wikipedia. The Free Encyclopedia: Discovery and Development of Proton Pump Inhibitors. (Accessed 7/1/2015).
   Google Scholar
• Sweetman, S. C. ed. Martindale “The Complete Drug Reference,” 36th Ed.; Pharmaceutical Press: London, 2009; 1729–1765 pp.
   Google Scholar
• http:/www.pharmainfo.net/reviews/proton-pump-inhibitors-overview(Accessed 7/1/2015).
   Google Scholar
• Quan, Z.; Xiao-Feng, Y.; Wen-Sheng, P.; Su, Z. Is the required therapeutic effect always achieved by racemic switch of proton-pump inhibitors? World Gastroenterrol., 2008, 14, 2617–2619.
   PubMed Web of Science ®Google Scholar
• Katzung, B. G.; Masters, S. B.; Trevor, A. J. Basic and Clinical Pharmacology, 11th Ed.; McGraw-Hill: Singapore, 2009, 55 p.
   Google Scholar
• Badwan, A. A.; Nabulsi, L. N.; Al-Omari, M. M.; Daraghmeh, N. H.; Ashour, M. K.; Abdoh, A. M.; Jaber, A. M. Y. Through Brittain, H.G. Analytical profiles of drug substances and excipients; Florey, K. Ed.; 2002, Vol. 29, 242–245 pp.
   Google Scholar
• SRS Pharmaceuticals Pvt. Ltd: Pharmaceutical, triple therapy for H.pylori. http://www.srspharma.com/triple-therapy-for-helicobacter-pylori.
   Google Scholar
• http://www.indiamart.com/rekvinapharmaceuticals/pharmaceutical-supplies.html
   Google Scholar
• The United States Pharmacopoeia, the National Formulary, 26th Ed.; US Pharmacopoeia Convention: Washington, D.C., 2012; 2502, 2851 pp.
   Google Scholar
• The European Pharmacopoeia, 6th Ed.; Council of Europe, 2008, 4137, 4249 pp.
   Google Scholar
• Bosch, M. E.; Sanchez, A. J.; Rojas, F. S.; Ojeda, C. B. Analytical Methodologies for the Determination of Omeprazole: An Overview. J. Pharm. Biomed. Anal. 2007, 44, 831–844.
   PubMed Web of Science ®Google Scholar
• Gupta, V.; Mishra, D.; Raj, K.; Dwiwedi, R.; Saini, D. R.; Narwal, S. A Review: Development and Validation of HPLC Method for Determination of Esomeprazole in Pharmaceuticals. Indo. Global J. Pharm. Sci. 2012, 2, 191–196.
   Google Scholar
• Ray, S.; Kumar, D. P. HPTLC and TLC Method for Rapid Quantitation and Identification of Omeprazole. Indian Drugs. 1994, 31, 543–547.
   Google Scholar
• Dogrukol, D.; Tunalier, Z.; Tuncel, M. TLC Densitometric of Omeprazole in Pharmaceutical Preparations. Pharmazie. 1998, 53, 272–273.
   Web of Science ®Google Scholar
• Jha, P.; Parveen, R.; Khan, S. A.; Alam, O.; Ahmad, S. J. Stability-indicating High-performance Thin-layer Chromatographic Method for Quantitative Determination of Omeprazole in Capsule Dosage Form. J. AOAC. Int. 2010, 93, 787–791.
   PubMed Web of Science ®Google Scholar
• Agbaba, D.; Novovic, D.; Karljiković-Rajić, K.; Marinković, V. Densitometric Determination of Omeprazole, Pantoprazole, and Their Impurities in Pharmaceuticals. J. Plan. Chromatogr. Mode TLC. 2004, 17, 169–172.
   Web of Science ®Google Scholar
• Raval, P. B.; Puranik, M.; Wadher, S. J.; Yeole, P. G. A Validated HPTLC Method for Determination of Ondansetron in Combination with Omeprazole or Rabeprazole in Solid Dosage Form. Indian J. Pharm. Sci. 2008, 70, 386–390.
   PubMed Web of Science ®Google Scholar
• Patel, B. H.; Patel, M.; Patel, J.; Suhagia, B. Simultaneous Determination of Omeprazole and Domperidone in Capsules by RP-HPLC and Densitometric HPTLC. J. Liqu. Chromatogr. 2007, 30, 1749–1762.
   Web of Science ®Google Scholar
• Salem, H.; Riad, S. M.; Reda, M.; Ahmed, K. Simultaneous Determination of Omeprazole, Tinidazole and Clarithromycin in Bulk Powder and Helicure Tablets by TLC Densitometric Technique. J. Pharm. Educ. Res. 2013, 4, 34–40.
   Google Scholar
• El-Kimary, E.; Ragab, M. A Validated High Performance Thin Layer Chromatographic Method for Assay of Two Binary Mixtures Containing Omeprazole or Its Isomer Esomeprazole in Pharmaceutical Dosage Forms. J. Plan. Chromatogr. 2015, 28 (1), 74–82.
   Web of Science ®Google Scholar
• Renger, B. J. Determination of Pantoprazole During Stability Studies. J. Am. Off. Anal. Chem. 1993, 76, 7–13. Through Analytical Profile, Vol. 29, 2002.
   Google Scholar
• Patel, B. H.; Suhagia, B. N.; Patel, M. M.; Patel, J. R. Simultaneous Estimation of Pantoprazole and Domperidone in Pure Powder and a Pharmaceutical Formulation by High Performance Liquid Chromatography and High Performance Thin Layer Chromatography Methods. J. AOAC. Int. 2007, 90, 142–146.
   PubMed Web of Science ®Google Scholar
• Gosavi, S. A.; Shirkhedkar, A. A.; Jaiswal, Y. S.; Surana, S. Quantitative Planar Chromatographic Analysis Of Pantoprazole Sodium Sesquihydrate And Domperidone In Tablets. J. Plan. Chromatogr. Mode TLC. 2007, 19, 302–306.
   Web of Science ®Google Scholar
• Patil, V. K.; Gawad, J. B. Statistical Evaluation of NP-HPTLC and RP-HPTLC Method for the Simultaneous Estimation of Cinitapride and Pantoprazole in Bulk and in Capsule Formulation. Indian J. Res. 2013, 3, 231–234.
   Google Scholar
• Rami, D.; Shahl, N. J. Application of HPTLC- Densitometric Analysis for Simultaneous Determination of Clidinium Bromide, Chlorodiazepoxide and Pantoprazole Sodium in their Combined Capsule Dosage Form. Int. Res. J. Pharm. 2013, 4, 161–166.
   Google Scholar
• Argekar, A. P.; Kunjir, S. S. Stability Indicating High Performance Thin Layer Chromatographic Method for the Quantification of Lansoprazole in Bulk Drug Substances and in Pharmaceutical Preparations. J. Plan. Chromatogr. Mod. TLC. 1996, 9, 296–299.
   Web of Science ®Google Scholar
• El-Sherif, Z. A.; Mohamed, A. O.; El-Bardeicy, M. G.; El-Tarras, M. F. Stability-indicating Methods for the Determination of Lansoprazole. Spectro. Lett. 2005, 38, 77–93.
   Web of Science ®Google Scholar
• Susheel, J. V.; Lekha, M.; Ravi, T. K. High Performance Thin Layer Chromatographic Estimation of Lansoprazole and Domperidone in Tablets. Indian. J. Pharm. Sci. 2007, 69, 684–686.
   Google Scholar
• Shirkhedkar, A. A.; Surana, S. J. Application of Stability Indicating RP-TLC Densitometric Determination of Rabeprazole Sodium in Bulk and Pharmaceutical Formulation. Eur. J. Anal. Chem. 2009, 4, 87–97.
   Google Scholar
• El-Gindy, A.; El-Yazby, F.; Maher, M. Spectrophotometric and Chromatographic Determination of Rabeprazole in Presence of Its Degradation Products. J. Pharm. Biomed. Anal. 2003, 31, 229–242.
   PubMed Web of Science ®Google Scholar
• Osman, A.; Osman, M. Spectrofluorometry, Thin Layer Chromatography, and Column High-performance Liquid Chromatography Determination of Rabeprazole Sodium in the Presence of Its Acidic and Oxidized Degradation Products. J. AOAC. Int. 2009, 92, 1373–1381.
   PubMed Web of Science ®Google Scholar
• Suganthi, A.; John, S.; Ravi, T. K. Simultaneous HPTLC Determination of Rabeprazole and Itopride Hydrochloride from Their Combined Dosage Form. Indian J. Pharm. Sci. 2008, 70, 366–368.
   PubMed Web of Science ®Google Scholar
• Rao, J. R.; Bharekar, V. V.; Mulla, T. S.; Yadav, S. S.; Rajput, M. P. Validated HPTLC Method for Simultaneous Estimation of Rabeprazole Sodium and Aceclofenac in Bulk Drug and Formulation. Int. J. Compreh. Pharm. 2011, 2, 1–4.
   Google Scholar
• Patel, B. H.; Suphagia, B. N.; Patel, M. M.; Patel, J. R. HPTLC Determination of Rabeprazole and Domperidone in Capsules and Its Validation. J. Chromatogr. Sci. 2008, 46, 304–307.
   PubMed Web of Science ®Google Scholar
• Mallikarjuna, R. N.; Bagyalakshmi, J.; Ravi, T. K. Development and Validation of Simultaneous Estimation of Paracetamol, Aceclofenac and Rabeprazole in Combined Tablet Dosage Formulation. Int. J. Bio. Pharm. Res. 2010, 1, 124–130.
   Google Scholar
• Mallikarjuna, R. N. Development and Validation of Stability Indicating HPTLC Method for Simultaneous Estimation of Paracetamol, Aceclofenac and Rabeprazole in Combined Tablet Dosage Formulation. Int. J. Pharm. Tech. Res. 2011, 3, 909–918.
   Google Scholar
• Gosavi, S. A.; Bhavar, G. B.; Chepurwar, S. B.; Shirkhedkar, A. A.; Bari, S. B.; Surana, S. J. Estimation of Esomeprazole in Bulk and Tablet Dosage Form by Use of Planar Chromatography. Res. J. Pharm. Technol. 2010, 3 (4), 1185–1188.
   Google Scholar
• Sharma, S.; Sharma, M. C. Densitometric Method for Quantitative Determination of Esomeprazole and Domperidone in Dosage Forms. Amer.-Euras. J. Toxicol. Sci. 2011, 3 (3), 143–148.
   Google Scholar
• Patel, R.; Kakadiya, J.; Patel, P.; Shah, N. Development and Validation of High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Levosulipride and Esomeprazole in Combined Pharmaceutical Formulation. World J. Pharm. Pharm. Sci. 2014, 3 (5), 1621–1636.
   Google Scholar
• Dhaneshwar, S. R.; Bhusari, V. K.; Mahadik, M. V.; Santakumari, B. Application of a Stability-indicating Thin-layer Chromatographic Method to the Determination of Tenatoprazole in Pharmaceutical Dosage Forms. J AOAC Int. 2009, 92 (2), 387–393.
   PubMed Web of Science ®Google Scholar
• Chitlange, S. S.; Mulla, A. I.; Pawbake, G. R.; Wankhede, S. B. Stability-indicating TLC-Densitometric Method for Estimation of Dexrabeprazole and Domperidone in Pharmaceutical Dosage Form. Prep. Biochem. Biotechnol. 2010, 40 (4), 337–346.
   PubMed Web of Science ®Google Scholar
• El-Kommos, M. E.; Khashaba, P. Y.; El-Wekil, M. M. Spectrodensitometric Determination of Some Pharmaceutical Mixtures Containing Proton Pump Inhibitors. J. Plan. Chromatogr. Mode TLC. 2013, 27 (3), 217–228.
   Web of Science ®Google Scholar
• He, Z. Studies on the Quantitative Determination of Omeprazole. Yaowu Fenix Zazhi. 1991, 11, 276–278.
   Google Scholar
• Person, B.; Wendsjo, S. Oxygen Effects in Amperometric Liquid Chromatographic Detection of Omeprazole at a Mercury Electrode. J. Chromatogr. A 1985, 321, 375–384.
   Web of Science ®Google Scholar
• Sluggett, G. W.; Stong, J. D.; Adams, J. H.; Zhao, Z. Omeprazole Determination Using HPLC with Coulometric Detection. J. Pharm. Biomed. Anal. 2001, 25, 357–361.
   PubMed Web of Science ®Google Scholar
• Nataraj, K. S.; Duza, M. B.; Pragallapati, K.; Kumar, D. K. Development and Validation of RP-HPLC Method for the Estimation of Omeprazole in Bulk and Capsule Dosage Forms. Int. Cur. Pharm. J. 2012, 1, 366–369.
   Google Scholar
• Chauhdry, A. H.; Malik, T. A.; Ashfaq, K. M.; Shafiq, M.; Aslam, M.; Akhtar, M. S. A Simple HPLC Method for the Determination of Omeprazole In Vitro. Int. Pharm. Chem. 2012, 2, 126–128.
   Google Scholar
• Dhanalakshmi, K.; Gopalakrishnan, S.; Jothy, K. Analytical Method Development and Validation of HPLC Method for the Determination of Omeprazole in Capsule Dosage Form. Elixir Appl. Chem. 2012, 52, 11283–11286.
   Google Scholar
• Schubert, A.; Werle, A. L.; Schmidt, C. A.; Lisiane, B.; Chiappa, R.; Cardoso, S. G. Determination of Omeprazole in Bulk and Injectable Preparations by Liquid Chromatography. J. AOAC. Int. 2003, 86, 501–504.
   PubMed Web of Science ®Google Scholar
• Iuga, C.; Bojita, M. Stability Study of Omeprazole. Pharmazia. 2010, 58, 203–210.
   Google Scholar
• Sankar, M.; Arulantony, S. A Validated Stability of Omeprazole Sodium Injection in 0.9% Sodium Chloride and 5% Dextrose Solutions by RP-HPLC. IOSR J. Pharm. 2013, 3, 24–30.
   Google Scholar
• El-Badry, M.; Taha, E. I.; Alanazi, F. K.; Alsarra, I. A. Study of Omeprazole Stability in Aqueous Solution: Influence of Cyclodextrin. J. Drug. Del. Sci. Tech. 2009, 19, 347–351.
   Web of Science ®Google Scholar
• Ribani, M.; Collins, C. H.; Bottoli, C. B. G. Validation of Chromatographic Methods: Evaluation of Detection and Quantification Limits in the Determination of Impurities in Omeprazole. J. Chromatogr. A 2007, 1156, 201–205.
   PubMed Web of Science ®Google Scholar
• Igua, C.; Bojita, M.; Leucuta, S. E. Development of a Validated RP-HPLC Method for Separation and Determination of Process-related Impurities of Omeprazole. Farmacia 2009, 57, 534–541.
   Web of Science ®Google Scholar
• Pujeri, S. S.; Khader, M. A.; Seetharamappa, J. Development and Validation of LC Method for the Assay of Omeprazole Enantiomers in Pharmaceutical Formulations. Der. Pharmacia. Lett. 2012, 4, 76–86.
   Google Scholar
• Carins, A. M.; Chiou, R. H. Y.; Rogers, J. D.; Demetriades, J. L. Enantioselective High Performance Liquid Chromatographic Determination of Omeprazole in Human Plasma. J. Chromatogr. B 1995, 666, 323–328.
   PubMedGoogle Scholar
• Zarapkar, S. S.; Kanyawar, N. S. Simultaneous HPLC Method for Determination Mixture of Omeprazole and Domperidone in Tablets. Indian Drugs 2002, 39, 217–221.
   Google Scholar
• Topagi, K. S.; Jeswani, R. M.; Sinha, P. K.; Damle, M. C. A Validated Normal HPLC for Simultaneous Determination of Drotaverine Hydrochloride and Omeprazole in Pharmaceutical Formulation. Asian J. Pharm. Sci. Clinic. Res. 2010, 3, 20–24.
   Google Scholar
• Dedani, Z.; Dedani, R.; Karkhanis, V.; Sagar, G. V.; Balda, M.; Sheth, N. R. RP-HPLC Method for Simultaneous Estimation of Omeprazole and Ondansetron in Combined Dosage Forms. Asian, J. Res. Chem. 2009, 2, 108–111.
   Google Scholar
• Darwish, K. M.; Salama, I.; Mostafa, S.; El-Sadek, M. RP-HPLC/Precolumn Derivatization for Analysis of Omeprazole, Tinidazole, Doxycycline and Clarithromycin. J. Chromatogr. Sci. 2013, 51, 566–576.
   PubMed Web of Science ®Google Scholar
• Salem, H.; Riad, S.; Rezk, M. R.; Ahmed, K. Simultaneous Determination Of Omeprazole, Tinidazole and Clarithromycin in Bulk powder and Helicure® Tablets by HPLC. J. Chromatogr. Sep. Tech. 2014, 5 (2), 1–5.
   Google Scholar
• Panigrahi, S.; Panda, S. K.; Mishra, P. R. Stability Indicating RP-HPLC Method for the Estimation of Esomeprazole in Bulk and in Its Dosage Forms. J. Adv. Pharm. Res. 2011, 2, 170–174.
   Google Scholar
• Nalwade, S. U.; Reddy, V. R.; Rao, D. D.; Morisetti, N. K. A Validated Stability Indicating Ultraperformance Liquid Chromatographic Method for Determination of Impurities in Esomeprazole Magnesium Gastroresistant Tablets. J. Pharm. Biomed. Anal. 2012, 57, 109–114.
   PubMedGoogle Scholar
• Patel, R. K.; Raval, B. P.; Patel, B. H.; Patel, L. J. Reverse Phase High Performance Liquid Chromatographic Method for the Simultaneous Estimation of Esomeprazole and Itopride in Capsule. Der. Pharm. Chem. 2010, 2, 251–260.
   Google Scholar
• Ashutosh, K. S.; Arumbaka, H.; Manidipa, D.; Sai, K. N.; Saravanan, J.; Greeshma, V.; Madhusudhan, R. C. N. A New, Simple and Accurate Method Development and Validation for Simultaneous Estimation of Esomeprazole and Itopride in Pharmaceutical Dosage Form by Using RP –HPLC. Res. J. Pharm. Technol. 2014, 7 (2), 221–228.
   Google Scholar
• Gohil, D.; Bhamre, P.; Jain, R.; Rajput, S. Simultaneous Estimation of Esomeprazole Magnesium Trihydrate, Itopride Hydrochloride and Mosapride Citrate by RP-HPLC Method: Optimization, Development, Validation and Application to Laboratory Sample. Int. J. Pharm. Sci. Res. 2014, 5 (3), 907–912.
   Google Scholar
• Kumar, S. A.; Debnath, M.; Rao, S. J. V. L. N. Simultaneous Estimation of Esomeprazole and Naproxene in Bulk as Well as Pharmaceutical Formulations by Using RP-HPLC. Int. J. Pharm. Sci. Res. 2013, 4, 2988–2999.
   Google Scholar
• Kayesh, R.; Sultan, M. Z. A Novel Ion-pair RP-HPLC Method for Simultaneous Quantification of Naproxen and Esomeprazole in Pharmaceutical Formulations. J. Chromatogr. Sci. 2015, 53 (5), 687–693.
   PubMed Web of Science ®Google Scholar
• Mahesh, H. R. K.; Babu, K. S.; Lanaka, R. P.; Pamidi, S. Simultaneous Estimation of Related Compounds in Esomeprazole and Naproxen by Using Ion-pair RP-HPLC. Int. J. Pharm. Pharm. Sci. 2015, 7 (2), 460–464.
   Google Scholar
• Poornima, A. N.; Satishkumar, S. A.; Ahmed, M.; Aradhya, V. K.; Ravi, M. C.; AnilKumar, S. M. RP-HPLC Method Development and Validation for Simultaneous Estimation of Esomeprazole and Ondansetron in Combined Tablet Dosage Form. World J. Pharm. Pharm. Sci. 2015, 4 (1), 1041–1051.
   Google Scholar
• Jain, R. R.; Patil, P. O.; Bari, S. B. Simultaneous Estimation of Esomeprazole and Levosulipride in Bulk and Capsules Formulation by RP-HPLC. J. Chil. Chem. Soc. 2013, 58 (3), 1846–1849.
   Web of Science ®Google Scholar
• Kumar, K. S.; Samnani, P. B. Development and Validation of a New HPLC Method for Simultaneous Determination of Esomeprazole, Venlafaxine HCl and Fenofibrate. Int. J. Chem. Tech. Res. 2014, 6 (1), 838–844.
   Google Scholar
• Sankar, D. G.; Raju, M. S. M.; Sastry, C. S. P. Spectrophotometric Determination of Pantoprazole by Precipitation Reactions and by HPLC. Asian. J. Chem. 2004, 16, 669–674.
   Web of Science ®Google Scholar
• Pushpalatha, K.; Ramachandran, D. Development and Validation of RP-HPLC Method for the Estimation of Pantoprazole. Int. J. Curr. Pharm. Res. 2013, 5, 119–121.
   Google Scholar
• Tanaka, M.; Yamazaki, H.; Hakushi, H. Direct HPLC Separation of Enantiomers of Pantoprazole and Other Benzimidazole Sulfoxides Using Cellulose-based Chiral Stationary Phases in Reversed-phase Mode. Chirality, 1995, 7, 612–615.
   Web of Science ®Google Scholar
• Guan, J.; Yang, J.; Bi, Y., Shi, S., Yan, F.; Li, F. Determination of the Enantiomeric in S-pantoprazole Using High Performance Liquid Chromatography with Sulfobutylether-beta-cyclodextrin as Chiral Additive. J. Sep. Sci. 2008, 14, 288–293.
   Google Scholar
• Mansour, A. M.; Sorour, O. M. High Performance Liquid Chromatographic Determination of Pantoprazole in Tablet Dosage Form. Chromatographia, 2001, 53 (suppl.), 478–479.
   Google Scholar
• Saini, V.; Gupta, V. B. Estimation of Pantoprazole from Multiparticulate Dosage Form by New HPLC Method. Int. J. Chem. Tech. Res. 2009, 1, 1094–1096.
   Google Scholar
• Emami, J.; Rezazadeh, M.; Kalani, M. Quantitation of Pantoprazole by High Performance Liquid Chromatography Method: In Vitro and In Vivo Applications. J. Liq. Chromatogr. Rel. Tech. 2014, 37 (5), 681–695.
   Web of Science ®Google Scholar
• Battu, P. R.; Jayaprakash, M.; Sivaji, K.; Jyothesh, G. T.; Surendranath, R. E. C.; Ravindra, R. B. Determination of Pantoprazole Sodium and Lansoprazole in Individual Dosage Tablets by RP-HPLC Using Single Mobile Phase. Int. J. Appl. Bio. Pharma. Tech. 2010, 1, 683–688.
   Google Scholar
• Sivakumar, T.; Manavalan, R.; Valliappan, K. Development and Validation of a Reversed Phase HPLC Method for Simultaneous Determination of Domperidone and Pantoprazole in Pharmaceutical Dosage Forms. Acta Chromatogr. 2007, 18, 130–142.
   Web of Science ®Google Scholar
• Battu, P. S. Simultaneous HPLC Estimation of Pantoprazole and Domperidone from Tablets. Int. J. Chem. Tech. Res. 2009, 1, 275–277.
   Google Scholar
• Rao, G. S.; Rao, A. B. N. N.; Reddy, G. R.; Shoeb, M. A.; Labamiwo, O. M.; Rao, J. V. L. N. S. RP-HPLC Method for Simultaneous Estimation of Domperidone and Pantoprazole in Capsule Dosage Form. Der Pharmacia. Lett. 2012, 4, 1712–1720.
   Google Scholar
• Sivakumar, T.; Manavalan, R.; Valliappan, K. Stability-indicating HPLC Method for Simultaneous Determination of Pantoprazole and Domperidone from Their Combination Drug Product. Chromatographia 2008, 67, 41–47.
   Web of Science ®Google Scholar
• Pandey, S.; Padey, P.; Mishra, D.; Singh, U. K. A Validated Stability Indication HPLC Method for the Determination of Process-related Impurities in Pantoprazole Bulk and Drug Formulations. Braz. J. Pharm. Sci. 2013, 49 (1), 175–184.
   Web of Science ®Google Scholar
• Hanumanturayudu, K.; Sreeramulu, J.; Maheswara, R. M. Stability Indicating Assay Method for Lansoprazole: A Comparative Study by UPLC. Experiment 2013, 7, 372–380.
   Google Scholar
• Basavaiah, K.; Ramakrishna, V.; Kumar, K. U. R.; Kumar, U. Spectrophotometric and High Performance Liquid-chromatographic Determination of Lansoprazole in Pharmaceuticals. Indian J. Chem. Technol. 2006, 13, 549–554.
   Web of Science ®Google Scholar
• Al-Momani, I. F.; Rababah, M. H. Validation of HPLC and FIA Spectrophotometric Methods for the Determination of Lansoprazole in Pharmaceutical Dosage Forms and Human Plasma. Amer. J. Anal. Chem. 2010, 1, 34–39.
   Google Scholar
• Kane, S. Y.; Snehalatha, B.; Momin, M. Simultaneous Determination of Lansoprazole and Metronidazole in Pharmaceutical Dosage Form by Reversed Phase- High Performance Liquid Chromatography. Int. J. Chem. Anal. Sci. 2014, 5 (2), 80–85.
   Google Scholar
• Halder, A.; Mandal, B. K.; Sridevi, R.; Navalgund, S. G. Validated RP-HPLC Method for Rabeprazole and Its Stability Studies. J. Pharm. Healthcare. Manag., 2011, 2, 76–82.
   Google Scholar
• Reddy, G. M., Bhaskar, B. V.; Reddy, P. P., Sudhakar, P.; Babu, J. M., Vyas, K.; Reddy, P. R.; Mukkantik, K. Identification and Characterization of Potential Impurities of Rabeprazole Sodium. J. Pharm. Biomed. Anal. 2007, 43, 1262–1269.
   PubMed Web of Science ®Google Scholar
• Garcia, C. V.; Paim, C. S.; Steppe, M. New Liquid Chromatographic Method for Determination of Rabeprazole Sodium in Coated Tablets. J. AOAC. Int. 2004, 87, 842–846.
   PubMed Web of Science ®Google Scholar
• Battu, P. R.; Reddy, M. S. Development and Validation of RP-HPLC for the Rabeprazole Sodium in Pharmaceutical Formulations and Human Plasma. Asian J. Res., Chem. 2009, 2, 49–51.
   Google Scholar
• Kulkarni, V. L.; Mahulikar, P. P. Estimation of Rabeprazole Sodium in Tablet Dosage Form by Rapid Isocratic Reversed Phase High Performance Liquid Chromatography Using Volatile Buffer Additives. J. Sci. Ind. Res. 2006, 65, 992–994.
   Web of Science ®Google Scholar
• Nawaz, M. S. Validation and Application of a New Reversed Phase HPLC Method for In Vitro Dissolution Studies of Rabeprazole Sodium in Delayed-release Tablets. J. Anal. Meth. Chem., 2013, 1, 1–8.
   Google Scholar
• Elumalai, S.; Aher, K.; Bhavar, G.; Gupta, S. Development and Validation of RP-HPLC Method for Determination of Content Uniformity of Rabeprazole Sodium in Its Tablets Dosage Forms. J. Appl. Pharm. Sci. 2011, 1, 165–170.
   Google Scholar
• Karunakaran, K.; Navaneethan, G.; Elango, K. P. Development of a New RP-UPLC Method for the Determination of Rabeprazole Sodium in Pharmaceutical Formulation and Application in Dissolution Studies. Trop. J. Pharm. Res. 2011, 10, 655–661.
   Web of Science ®Google Scholar
• Kalirajan, R.; Anandarajagopal, K.; Mathew, S. M.; Gowramma, B.; Jubie, S.; Suresh, B. Simultaneous Determination of Rabeprazole and Domperidone in Dosage Forms by RP-HPLC. J. Chem. 2008, 1, 232–235.
   Google Scholar
• Patel, B. H.; Patel, M.; Patel, J.; Suhagia, B. HPLC Analysis for Simultaneous Determination of Rabeprazole and Domperidone in Pharmaceutical Formulation. J. Liq. Chromatogr. 2007, 30, 439–445.
   Web of Science ®Google Scholar
• Ghoudhary, B.; Goyal, A.; Khokra, S. L.; Kaushik, D. Simultaneous Estimation of Diclofenac Sodium and Rabeprazole by High Performance Liquid Chromatographic Method in Combined Dosage Forms. Int. J. Pharm. Sci. Drug. Res. 2009, 1, 43–45.
   Google Scholar
• Birajdar, A. S.; Meyyanathan, S.; Suresh, B. A Reversed HPLC Method for Determination of Aceclofenac with Rabeprazole in Solid Dosage Form. Int. J. Pharm. Sci. 2011, 2, 171–178.
   Google Scholar
• Khokra, S. L., Choudhary, B.; Mehta, H. RP-HPLC Analysis for the Simultaneous Estimation of Rabeprazole Sodium and Aceclofenac in a Combined Dosage Form. Int. J. Cur. Pharm. Res. 2012, 1, 410–413.
   Google Scholar
• El-Fatatry, H. M.; Mabrouk, M. M., Hewala, I. I.; Emam, E. H. Stability-indicating HPLC–DAD Methods for Determination of Two Binary Mixtures: Rabeprazole Sodium-mosapride Citrate and Rabeprazole Sodium-itopride Hydrochloride. J. Pharm. Anal. 2013, 4 (4), 1–12.
   Google Scholar
• Saravanan, G.; Padmaja, J.; Geethanjali, J.; Visagaperumal, D. Stability Indicating RP-HPLC Method for Estimation of Rabeprazole Sodium and Mosapride Citrate in Bulk and Formulation. Int. J. Pharm. Pharm. Sci. 2014, 6 (11), 265–269.
   Google Scholar
• Chitlange, S. S.; Mulla, A. I.; Pawbake, G. R.; Wankhede, S. B. A Validated RP-HPLC Method for Simultaneous Estimation of Dexrabeprazole and Domperidone in Pharmaceutical Dosage Form. Pharm. Sin. 2010, 1, 42–47.
   Google Scholar
• Dhaneshwar, S. R., Jagtap, V. N. Development and Validation of Stability Indicating RP-HPLC-PDA Method for Tenatoprazole and Its Application for Formulation Analysis and Dissolution Study. Amer. J. Anal. Chem. 2011, 2, 126–134.
   Google Scholar
• Sugumaran, M.; Poornima, M.; Kumar, M. Y.; Ramarajasekhar, S. RP-HPLC Method for the Determination of Tenatoprazole in Pharmaceutical Formulation. Pharm. Sin. 2011, 12–16.
   Google Scholar
• Cirilli, R.; Ferretti, R.; Gallinella, B.; Santis, E. D.; Zanitti, L.; Torre, F. L. High-performance Liquid Chromatography Enantioseparation of Proton Pump Inhibitors Using the Immobilized Amylose-based Chiralpak IA Chiral Stationary Phase in Normal-phase, Polar Organic and Reversed-phase Conditions. J. Chromatogr. A 2008, 1177, 105–113.
   PubMed Web of Science ®Google Scholar
• Ekpe, A.; Jacobsen, T. Effect of Various Salts on the Stability of lansoprazole, Omeprazole, and Pantoprazole as Determined by High-performance Liquid Chromatography. Drug Develop. Indian. Pharm. 1999, 25, 1057–1065.
   PubMed Web of Science ®Google Scholar
• El-Sherif, Z. A.; Mohammed, A. O.; El-Baradicy, M. G.; El-Tarras, M. F. Reversed-phase High Performance Liquid Chromatographic Method for the Determination of Lansoprazole, Omeprazole and Pantoprazole Sodium Sesquihydrate in Presence of Their Acid-induced Degradation Products. Chem. Pharm. Bull. 2006, 54, 814–818.
   PubMed Web of Science ®Google Scholar
• Patel, B. H.; Suphagia, B. N.; Patel, M. M., Patel, J. R. Determination of Rabeprazole, Esomeprazole, Domperidone and Itopride in Pharmaceutical Products by Reversed Phase Liquid Chromatography Using Single Mobile Phase. Chromatographia 2007, 65, 743–748.
   Web of Science ®Google Scholar
• Tivesten, A.; Folestad, S.; Schonbacher, V.; Svensson, K. Non-aqueous Capillary Electrophoresis for the Analysis of Labile Pharmaceutical Compounds. Chromatographia 1999, 49 (Suppl. I), 7–11.
   Google Scholar
• Lin, L. H.; Wu, S. M. Analysis of Omeprazole and Lansoprazole in Capsules by Capillary Zone Electrophoresis. LC-GC Europe 2005, 18 (3), 164–167.
   Web of Science ®Google Scholar
• Berzas, N. J. J.; Peñalvo, G. C.; Rodríguez, D. R. M. Method Development and Validation for the Separation and Determination of Omeprazole Enantiomers in Pharmaceutical Preparations by Capillary Electrophoresis. Anal. Chim. Acta 2005, 533 (2), 127–133.
   Web of Science ®Google Scholar
• Olsson, J.; Stegandera, F.; Marlina, N.; Wanb, H.; Blomberg, L. G. Enantiomeric Separation of Omeprazole and Its Metabolite 5-Hydroxyomeprazole Using Non-aqueous Capillary Electrophoresis. J. Chromatogr. A 2006, 1129 (2), 291–295.
   PubMed Web of Science ®Google Scholar
• Bonato, P. S.; Paiasb, F. O. Enantioselective Analysis of Omeprazole in Pharmaceutical Formulations by Chiral High-Performance Liquid Chromatography and Capillary Electrophoresis. J. Braz. Chem. Soc. 2004, 15 (2), 318–323.
   Web of Science ®Google Scholar
• Hancu, G.; Papp, L. A.; Rusu, A. Chiral Separation of the Enantiomers of Omeprazole and Pantoprazole by Capillary Electrophoresis. Chromatographia 2015, 78 (3–4), 279–284.
   Web of Science ®Google Scholar
• Estevez, P.; Flor, S.; Boscolo, O.; Tripodi, V.; Lucangioli, S. Development and Validation of a Capillary Electrophoresis Method for Determination of Enantiomeric Purity and Related Substances of Esomeprazole in Raw Material and Pellets. Electrophoresis 2014, 35 (6), 804–810.
   PubMed Web of Science ®Google Scholar
• Guan, J.; Yan, F.; Shi, S.; Wang, S. Optimization and Validation of a New CE Method for the Determination of Pantoprazole Enantiomers. Electrophoresis 2012, 33 (11), 1631–1636.
   PubMed Web of Science ®Google Scholar
• Guan, J.; Li, H.; Yan, F.; Shi, S.; Wang, S. Optimization and Validation of a Novel CE Method for the Enantioseparation of Pantoprazole and Related Benzimididazole Using a Dual Chiral Selector System. Electrophoresis 2014, 35 (19), 2800–2806.
   PubMed Web of Science ®Google Scholar
• Dogrukol, A. K.; Tuncel, M.; Aboul-Enein, H. Y. The Determination of Lansoprazole in Pharmaceutical Preparation by Capillary Electrophoresis. Chromatographia 2001, 54, 527–530.
   Web of Science ®Google Scholar
• Nevado, J. J. B.; Penavlo, V. G. C.; Sanchez, J. C. J.; Mochon, M. C.; Dorado, R. M. R.; Navarro, M. V. Optimisation and Validation of a New CE Method for the Determination of Lansoprazole Enantiomers in Pharmaceuticals. Electrophoresis 2009, 30, 2940–2946.
   PubMed Web of Science ®Google Scholar
• Garcia, C. V.; Sippel, J.; Sfair, L. L.; Garcia, S. S.; Jablonski, A.; Steppe, M.; Schapoval, E. E. S. Validation of a Capillary Electrophoresis Method for Analysis of Rabeprazole Sodium in a Pharmaceutical Dosage Form. J. AOAC. Int. 2005, 88, 1081–1085.
   PubMed Web of Science ®Google Scholar
• Manglan, S.; Patel, R. B.; Chakravarthy, B. K. Detection and Determination of Omeprazole by HPTLC: A Reliable Method for the Estimation of Plasma Levels. J. Plan. Chromatogr. Mod. TLC 1991, 4, 492–493.
   Google Scholar
• Pandya, K. K.; Mody, V. D.; Satia, M. C.; Modi, I. A.; Modi, R. I.; Chakravarthy, B. K.; Gandhi, T. P. High Performance Thin Layer Chromatographic Method for the Detection and Determination of Lansoprazole in Human Plasma and Its Use in Pharmacokinetic Studies. J. Chromatogr. B. 1997, 693, 199–204.
   PubMedGoogle Scholar
• Igua, C.; Moldivan, M.; Popa, A.; Leucuta, S. E. Validation of HPLC-UV Method for Analysis of Omeprazole in Presence of Its Metabolites in Human Plasma. Farmacia 2008, 3, 254–260.
   Google Scholar
• Xu, X. Y.; Lu, T. H.; Wang, M. L.; Xu, C.; Wang, R. L.; He, L. Y. Determination of Omeprazole Capsules in Human Plasma by Reversed Phase HPLC. Yaowu Fenix Zazhi 1997, 17, 169–171.
   Google Scholar
• Garacia–Encina, G.; Farran, R.; Puig, S.; Martinez, L. Validation of an Automated Liquid Chromatographic Method for Omeprazole in Human Plasma Using On-line Solid-phase Extraction. J. Pharm. Biomed. Anal. 1999, 21, 371–382.
   PubMed Web of Science ®Google Scholar
• Yuen, K. H.; Choy, W. P.; Tan, H. Y.; Wong, J. W.; Yap, S. P. Improved High Performance Liquid Chromatographic Analysis of Omeprazole in Human Plasma. J. Pharm. Biomed. Anal. 2001, 24, 715–719.
   PubMed Web of Science ®Google Scholar
• Wang, J.; Wang, Y.; Fawcett, J. P.; Wang, J.; Gu, J. Determination of Omeprazole in Human Plasma by Liquid Chromatography–electrospray Quadrupole Linear Ion Trap Mass Spectrometry. J. Pharm. Biomed. Anal. 2005, 39, 631–635.
   PubMed Web of Science ®Google Scholar
• Vittal, S.; Ganneboina, R.; Layek, B.; Trivedi, R. K.; Hotha, K. K.; Bharathi, D. V.; Mullangi, R. Highly Sensitive Method for the Determination of Omeprazole in Human Plasma by Liquid Chromatography-electrospray Ionization Tandem Mass Spectrometry: Application to a Clinical Pharmacokinetic Study. J. Biomed. Chromatogr. 2009, 20, 390–396.
   Google Scholar
• Macek, J.; Racek, P.; Klima, P. J. Determination of Omeprazole in Human Plasma by High Performance Liquid Chromatography. J. Chromatogr B. 1997, 689, 239–243.
   PubMed Web of Science ®Google Scholar
• Kang, W. K.; Kim, D. S.; Kwon, K. I. Advanced Method for Determination of Omeprazole in Plasma by HPLC. Arch. Pharm. Res. 1996, 22, 86–88.
   Google Scholar
• Ahmad, L.; Iqbal, Z.; Nazir, S.; Shah, Y.; Khan, A.; Khan, M. I.; Nasir, F.; Khan, A. Optimization and Validation of HPLC-UV Method for Simultaneous Determination of Omeprazoe and Its Metabolites in Human Plasma: Effects of Various Experimental Conditions and Parameters. J. Liq. Chromatogr. Rel. Tech. 2011, 34 (15), 1488–1501.
   Web of Science ®Google Scholar
• Jia, H.; Li, W.; Zhao, K. Determination of Omeprazole in Rat Plasma by High Performance Liquid Chromatography without Solvent Extraction. J. Chromatogr. B. 2006, 10, 112–115.
   Google Scholar
• Kobayashi, K.; Chiba, K.; Tani, M.; Kuroiwa, Y.; Ishizaki, T. Development and Preliminary Application of a High Performance Liquid Chromatography Assay for Omeprazole Metabolism in Human Liver Microsomes. J. Pharm. Biomed. Anal. 1994, 12, 839–844.
   PubMed Web of Science ®Google Scholar
• Andersson, T.; Lagerstrom, P. O.; Miners, J. O.; Veronese, M. E.; Weidolf, L.; Birkett, D. J. High Performance Liquid Chromatography Assay of Human Liver Microsomal Omeprazole Metabolism. J. Chromatogr. Biomed. Appl. 1993, 130, 291–297.
   Google Scholar
• Erlandsson, P.; Issaksson, R.; Lorentzon, P.; Lindberg, P. Resolution of the Enantiomers of Omeprazole and Some of Its Analogues by Liquid Chromatography on a Triphenylcarbamoylcellulose-based Stationary Phase. The Effect of Enantiomers of Omeprazole on Gastric Glands. J. Chromatogr. Biomed. Appl. 1990, 97, 305–319.
   Google Scholar
• Cass, Q. S.; Lima, V. V.; Oliveira, R. V.; Cassiano, N. M.; Degani, A. L.; Pedrazzoli, J. Enantiomeric Determination of the Plasma Levels of Omeprazole by Direct Plasma Injection Using High-performance Liquid Chromatography with a Chiral-chiral Column-switching. J. Chromatogr. B 2003, 798, 275–281.
   PubMed Web of Science ®Google Scholar
• Oralndo, R. M.; Bonato, P. S. Simple and Efficient Method for Enantioselective Determination of Omeprazole in Human Plasma. J. Chromatogr. B 2003, 795, 227–235.
   PubMed Web of Science ®Google Scholar
• Kanazawa, K.; Okada, A.; Hygaky, M.; Yakota, H.; Mashige, F.; Nakahara, K. Stereospecific Analysis of Omeprazole in Human Plasma as a Probe for CYP2C19 Phenotype. J. Pharm. Biomed. Anal. 2003, 30, 1817–1824.
   PubMed Web of Science ®Google Scholar
• Shiohira, H.; Yasui-Furukori, N.; Tateishi, T.; Uno, T. Chiral Assay of Omeprazole and Metabolites and Its Application to a Pharmacokinetics Related to CYP2C19 Genotypes. J. Chromatogr. B 2011, 879 (24), 2465–2470.
   PubMed Web of Science ®Google Scholar
• Yeung, P. K.; Little, R.; Jiang, Y.; Buckley, S. J.; Pollak, P. T.; Kapoor, H.; Van Zanten, S. J. A Simple High-performance Liquid Chromatography Assay for Simultaneous Determination of Omeprazole and Tinidazole in Human Plasma and Gastric Fluid. J. Pharm. Biomed. Anal. 1998, 17, 1393–1398.
   PubMed Web of Science ®Google Scholar
• Li, Z.; Yao, J.; Zhang, Z.; Zhang, L. Simultaneous Determination of Omeprazole and Domperidone in Dog Plasma by LC-MS Method. J. Chromatogr. Sci. 2009, 47, 881–884.
   PubMed Web of Science ®Google Scholar
• Tata, P. N.; Bramer, S. L. High-performance Liquid Chromatographic Method for the Analysis of Omeprazole and 5-Hydroxyomeprazole in Human Plasma. Anal. Lett. 1999, 32, 2285–2295.
   Web of Science ®Google Scholar
• Karlsson, A.; Hermansson, S. Optimization of Chiral Separation of Omeprazole and One of Its Metabolites on Immobilized α1-Acid Glycoprotein Using Chemometrics. Chromatographia 1997, 44, 10–18.
   Web of Science ®Google Scholar
• Motevalian, M.; Saeedi, G.; Keyhanfar, F.; Tayebi, L.; Mahmoudi, M. Simultaneous Determination of Omeprazole and Its Metabolites in Human Plasma by HPLC Using Solid Phase Extraction. J. Pharm. Pharmacol. Commun. 1999, 5, 265–268.
   Google Scholar
• Kobayashi, K.; Chiba, K.; Sohn, D. R.; Kato, Y.; Ishizaki, T. Simultaneous Determination of Omeprazole and Its Metabolites in Plasma and Urine by Reversed Phase High-performance Liquid Chromatography with Alkaline Resistant Polymer Coated C18 Column. J. Chromatogr. Biomed. Appl. 1992, 117, 299–305.
   Google Scholar
• Amantea, M. A.; Narang, P. K. Improved Procedure for Quantitation of Omeprazole and Metabolites Using Reversed Phase High Performance Chromatography. J. Chromatogr. Biomed. Appl. 1988, 70, 216–222.
   Google Scholar
• Grundevik, I.; Terndal, G.; Balmer, K.; Persson, B. A. Fully Automated Gradient Elution Liquid Chromatographic Assay and Two Metabolites. J. Pharm. Biomed. Anal. 1986, 4, 389–398.
   PubMed Web of Science ®Google Scholar
• Ramble-Alegre, M.; Romero, J. E.; Carda-Broch, S. Analysis of Omeprazole and Its Main Metabolites by Liquid Chromatography Using Hybrid Micellar Mobile Phase. Anal. Chim. Acta 2009, 633, 250–256.
   PubMed Web of Science ®Google Scholar
• González, H. M.; Romero, E. B.; Chavez, T. D.; Peregrina, A.; Quezada, V.; Hoyo-Vadillo, C. Phenotype of CYP2C19 and CYP3A4 by Determination of Omeprazole and Its Two Main Metabolites in Plasma Using Liquid Chromatography with Liquid–liquid Extraction. J. Chromatogr. B 2002, 25, 459–465.
   Google Scholar
• Shimizu, M.; Uno, T.; Niioka, T.; Yaui-Furukori, N.; Takahata, T.; Sugawara, K.; Tateishi, T. Sensitive Determination of Omeprazole and Its Two Main Metabolites in Human Plasma by Column-switching High-performance Liquid Chromatography: Application to Pharmacokinetic Study in Relation to CYP2C19 Genotypes. J. Chromatogr. B 2006, 20, 241–248.
   Google Scholar
• Motevalian, M.; Saeedi, G.; Keyhanfar, F.; Tayebi, L.; Mahmoudian, M. Simultaneous Determination of Omeprazole and Its Metabolites in Human Plasma by HPLC Using Solid Phase Extraction. J. Pharm. Pharmacol. 2010, 5, 265–268.
   Google Scholar
• Lagestrom, P. O.; Presson, B. A. Determination of Omeprazole and Metabolites in Plasma and Urine by Liquid Chromatography. J. Chromatogr. B. 1984, 34, 347–356.
   Google Scholar
• Mihaly, G. W.; Prichard, P. J.; Smallwood, R. A.; Yeomans, N. D.; Louis, W. J. Simultaneous High-performance Liquid Chromatographic Analysis of Omeprazole and Its Sulphone and Sulphide Metabolites in Human Plasma and Urine. J. Chromatogr. B 1983, 29, 311–319.
   Google Scholar
• Lobenhoffer, J. M.; Reiche, I.; Troger, U.; Monkemuller, K.; Malfertheiner, P.; Stefanie, M. P. Enantioselective Quantification of Omeprazole and Its Main Metabolites in Human Serum by Chiral HPLC–atmospheric Pressure Photoionization Tandem Mass Spectrometry. J. Chromatogr. B 2007, 857, 301–307.
   PubMed Web of Science ®Google Scholar
• Woolf, E. J.; Mauszewski, B. K. Simultaneous Determination of Omeprazole and 5′-Hydroxyomeprazole in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry. J. Chromatogr. A 1998, 828, 229–238.
   PubMed Web of Science ®Google Scholar
• Song, Q.; Naidong, N. Analysis of Omeprazole and 5-OH Omeprazole in Human Plasma Using Hydrophilic Interaction Chromatography with Tandem Mass Spectrometry (HILIC-MS/MS)–Eliminating Evaporation and Reconstitution Steps in 96-Well Liquid/liquid Extraction. J. Chromatogr. B 2006, 830, 135–142.
   PubMed Web of Science ®Google Scholar
• Gyllenhall, O.; Vessman, J. Packed-column Supercritical Fluid Chromatography of Omeprazole and Related Compounds: Selection of Column Support with Triethylamine- and Methanol-modified Carbon Dioxide as the Mobile Phase. J. Chromatogr. A 1993, 628, 275–281.
   Web of Science ®Google Scholar
• Mogili, R.; Bannoth, K. K. C. K.; Chandu, B. R.; Challa, B. R. Quantification of Esomeprazole in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry and Its Application to Bioequivalence Study. Pharm. Lett. 2011, 3, 138–145.
   Google Scholar
• Sundar, B. S.; Satyadev, T. N. V. S. S.; Sudhir, K. V. R.; Santosh, T. Development and Validation on High Performance Liquid Chromatographic Method for the the Determination of Esomeprazole in Human Plasma. Int. J. Res. Pharm. Chem. 2013, 3, 552–559.
   Google Scholar
• Zanetti, L.; Ferretti, R.; Gallinella, B.; La Torre, F.; Sanna, M. L.; Mosca, A.; Cirilli, R. Direct HPLC Enantioseparation of Omeprazole and Its Chiral Impurities: Application to the Determination of Enantiomeric Purity of Esomeprazole Magnesium Trihydrate. J. Pharm. Biomed. Anal. 2010, 52, 665–671.
   PubMed Web of Science ®Google Scholar
• Gopinath, S.; Kumar, R. S.; Shankar, M.; Danabal, P. Development and Validation of a Sensitive and High-throughput LC-MS/MS Method for the Simultaneous Determination of Esomeprazole and Naproxen in Human Plasma. J. Biomedical Chromatogr. 2013, 27 (7), 894–899.
   PubMed Web of Science ®Google Scholar
• Borner, K.; Borner, E.; Lode, H. Quantitative Determination of Lansoprazole in Human Serum by HPLC. Chromatographia 1997, 45, 450–452.
   Web of Science ®Google Scholar
• Karol, M. D.; Granneman, G. R.; Alexander, K. Determination of Lansoprazole and Five Metabolites in Plasma by High Performance Liquid Chromatography. J. Chromatogr. B 1995, 668, 182–186.
   PubMedGoogle Scholar
• Landes, B. D.; Miscoria, G.; Flovat, B. Determination of Lansoprazole and Its Metabolites in Plasma by High-performance Liquid Chromatography Using a Loop Column. J. Chromatogr. Biomed. Sci. Appl. 1992, 577, 117–122.
   Google Scholar
• Aoki, I.; Okumura, M.; Yashiki, T. High Performance Liquid Chromatographic Determination of Lansoprazole and Its Metabolites in Human Serum and Urine. J. Chromatogr. Biomed. Appl. 1991, 109, 283–290.
   Google Scholar
• Miura, M.; Tada, H.; Suzuki, T. Simultaneous Determination of Lansoprazole Enantiomers and Their Metabolites in Plasma by Liquid Chromatography with Solid-phase Extraction. J. Chromatogr. B. 2004, 204, 389–395.
   Google Scholar
• Borner, K.; Borner, E., Lode, H. Separation of Lansoprazole Enantiomers in Human Serum by HPLC. Chromatographia 1998, 47, 171–175.
   Web of Science ®Google Scholar
• Katsuki, H.; Hamada, A.; Nakamura, C.; Arimori, K.; Nakano, M. High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Lansoprazole Enantiomers and Metabolites in Human Liver Microsomes. J. Chromatogr. B. 2001, 757, 127–133.
   PubMed Web of Science ®Google Scholar
• Gomes, R. F.; Cassiano, N. M.; Pedrazzoli, J.; Qass, Q. B. Two-dimensional Chromatography Method Applied to the Enantiomeric Determination of Lansoprazole in Human Plasma by Direct Sample Injection. Chirality 2010, 22, 35–41.
   PubMed Web of Science ®Google Scholar
• Crilli, R.; Ferretti, R.; Gallinella, B.; Turchetto; Zanitti, L.; La Torre, F. Development and Validation of an Enantioselective and Chemoselective HPLC Method Using a Chiralpak IA Column to Simultaneously Quantify (R)-(+)- and (S)-(−)-lansoprazole Enantiomers and Related Impurities. J. Pharm. Biomed. Anal. 2009, 50, 9–14.
   PubMed Web of Science ®Google Scholar
• Kachave, R.; Kale, M.; Wagh, R. D. Development and Validation of a LC-MS/MS Method to Determine Lansoprazole in Human Plasma. Open Anal. Chem. J. 2015, 8, 7–11.
   Google Scholar
• Wang, H.; Sun, Y.; Meng, X.; Yang, B.; Wang, J.; Yang, Y.; Gu, J. Determination of Lansoprazole Enantiomers in Dog Plasma by Column-switching Liquid Chromatography with Tandem Mass Spectrometry and Its Application to a Preclinical Pharmacokinetic Study. J. Sep. Sci. 2015, 38, 2960–2967.
   PubMed Web of Science ®Google Scholar
• Battu, P. R.; Reddy, N. K. K. Development and Validation of RP-HPLC for the Pantoprazole Sodium Sesquihydrate in Pharmaceutical dosage forms and Human Plasma. Int. J. Chem. Tech. Res. 2009, 1, 195–198.
   Google Scholar
• Ramakrishna, N. V.; Vishwottam, K. N.; Wishu, S.; Koteshwara, M. High Performance Liquid Chromatography Method for Quantitation of Pantoprazole in Human Plasma. J. Chromatogr. B 2005, 822, 326–329.
   PubMed Web of Science ®Google Scholar
• Koçyiğit-Kaymakçoğlu, B.; Unsalan, S.; Rollas, S. Determination and Validation of Ketoprofen, Pantoprazole and Valsartan Together in Human Plasma by High Performance Liquid Chromatography. Pharmazie 2006, 61, 586–589.
   PubMed Web of Science ®Google Scholar
• Mohankandhasamy, R.; Dharuman, J.; Ponnilavarasan, I.; Thiagarajan, M. High-performance Liquid Chromatography Method for the Quantification of Pantoprazole in Rat Plasma. Int. J. Chem. Tech. Res. 2010, 2, 885–894.
   Google Scholar
• Abdelhameed, A. S.; Afifi, S. A. A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma. J. Chem. 2014, 2014, 1–8.
   Google Scholar
• Zhang, Y.; Chen, X.; Gu, Q.; Zhong, D. Quantification of Rabeprazole in Human Plasma by Liquid Chromatography–Tandem Mass Spectrometry. Anal. Chim. Acta 2004, 523, 171–175.
   Web of Science ®Google Scholar
• Singh, S. S.; Jain, M.; Shah, M.; Gupta, S.; Thakker, R.; Shah, R.; Lohray, B. B. Direct Injection, Column Switching–liquid Chromatographic Technique for the Estimation of Rabeprazole in Bioequivalence Study. J. Chromatogr. B 2004, 813, 247–254.
   PubMed Web of Science ®Google Scholar
• Park, C. W.; Rhee, Y. S.; Go, B. W.; Kam, S. H.; Lee, H. S.; Park, E. S. High Performance Liquid Chromatographic Analysis of Rabeprazole in Human Plasma and Its Pharmacokinetic Application. Arch. Pharm. Res. 2008, 31, 1195–1199.
   PubMed Web of Science ®Google Scholar
• Hunfeld, N. G. M.; Van Rossen, R. C. J. M.; Geus, W. P.; Touw, D. Determination of Rabeprazole and Metabolite in Human Serum Using High Speed HPLC. J. EJHP. Sci. 2008, 14, 8–13.
   Google Scholar
• Huang, J.; Xu, Y.; Gao, S.; Rui, L.; Guo, Q. Development of a Liquid Chromatography/Tandem Mass Spectrometry Assay for the Quantification of Rabeprazole in Human Plasma. Mass Spect. 2005, 19, 2321–2324.
   Google Scholar
• Simpemba, E.; Liu, R.; Sun, C.; Agbokponto, J. E.; Ding, L. Simultaneous Determination of Rabeprazole and Its Two Active Metabolites in Human Urine by Liquid Chromatography with Tandem Mass Spectrometry and Its Application in a Urinary Excretion Study. J. Sep. Sci. 2014, 37 (15), 1951–1956.
   PubMed Web of Science ®Google Scholar
• Lua, C.; Jiaa, C.; Songa, Y.; Lia, X.; Suna, Y.; Zhaoa, J.; Wanga, S.; Shic, L.;Wena, A.; Dingb, L. Application of a Liquid Chromatographic/Tandem Mass Spectrometric Method to a Urinary Excretion Study of Rabeprazole and Two of Its Metabolites in Healthy Human Urine. J. Chromatogr. B 2015, 988, 75–80.
   PubMed Web of Science ®Google Scholar
• Ibrahim, F.; Wahbi, M. E. K. Liquid Chromatography Coupled with Fluorimetric Detection and Third Derivative Synchronous Fluorescence Spectroscopy as Two Analytical Methods for the Simultaneous Determination of Rabeprazole Sodium and Domperidone After Derivatization with 4-Chloro-7-Nitrobenzofurazan. J. Fluoresc. 2014, 24 (4), 1137–1147.
   PubMed Web of Science ®Google Scholar
• Noubarani, M.; Keyhanfar, F.; Motevalian, M.; Mahmoudian, M. Improved HPLC Method for Determination of four PPIs, Omeprazole, Pantoprazole, Lansoprazole, Rabeprazole in Human Plasma. J. Pharm. Pharm. Sci. 2010, 13, 1–10.
   PubMed Web of Science ®Google Scholar
• Bharathi, D. V.; Hotha, K. K.; Jagadeesh, B.; Chatki, P. K.; Thriveni, K.; Mullangi, R.; Naidu, R. Simultaneous Estimation of Four Proton Pump Inhibitors: Lansoprazole, Omeprazole, Pantoprazole and Rabeprazole: Development of a Novel Generic HPLC-UV Method and Its Application to Clinical Pharmacokinetic Study. J. Biomed. Chromatogr. 2009, 23, 732–739.
   PubMed Web of Science ®Google Scholar
• Dixit, S.; Dubey, R.; Ravi, B. Normal and Polar-organic-phase High-performance Liquid Chromatographic Enantio Resolution of Omeprazole, Rabeprazole, Lansoprazole and Pantoprazole Using Monochloro-methylated Cellulose-based Chiral Stationary Phase and Determination of Dexrabeprazole. J. Biomed. Chromatogr. 2014, 28, 112–119.
   PubMed Web of Science ®Google Scholar
• Hotha, K. K., Bharathi, D. V.; Jagadeesh, B.; Ravindranath, L. K.; Jaya Veera, K. N.; Venkateswarulu, V. Development and Validation of a Highly Sensitive LC-MS/MS Method for Quantitation of Dexlansoprazole in Human Plasma: Application to a Human Pharmacokinetic Study. J. Biomed. Chromatogr. 2012, 26, 192–198.
   PubMed Web of Science ®Google Scholar
• Nevado, J. J. B.; Penalvo, G. C.; Dorado, R. M. R.; Virginia, R. V. R. Simultaneous Determination of Omeprazole and Their Main Metabolites in Human Urine Samples by Capillary Electrophoresis Using Electrospray Ionization-mass Spectrometry Detection. J. Pharm. Biomed. Anal. 2014, 92, 211–219.
   PubMed Web of Science ®Google Scholar
• Pérez-Ruiz, T.; Martínez-Lozano, C.; Sanz, A.; Bravo, E.; Galera, R. Determination of Omeprazole, Hydroxyomeprazole and Omeprazole Sulfone Using Automated Solid Phase Extraction and Micellar Electrokinetic Capillary Chromatography. J. Pharm. Biomed. Anal. 2006, 42, 100–106.
   PubMed Web of Science ®Google Scholar