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Original Articles

HPLC Analysis of Antipsychotic Asenapine in Alternative Biomatrices: Hair and Nail Clippings

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References

  • Alphs, L.; Panagides, J.; Lancaster, S. Asenapine in the treatment of negative symptoms of schizophrenia: clinical trial design and rationale. Psychopharmac. Bul. 2007, 40 (2), 41–53.
  • http://files.shareholder.com/downloads/AMDA-GGC00/0x0x503112/59d29e0e-8208-4656-8f1b-71ad41655b65/Release%20no%20413.pdf (accessed Feb 19, 2015).
  • http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001177/human_med_001379.jsp&murl=menus/medicines/medicines.jsp&mid=WC0b01ac058001d124&jsenabled=true (accessed Feb 19, 2015).
  • Chhalotitya, U. K.; Bhatt, K.; Shah, D. A.; Patel, J. R. Stability-Indicating Liquid Chromatographic Method for the Quantification of the New Antipsychotic Agent Asenapine in Bulk and in Pharmaceutical Formulation. Sci Pharm. 2012, 80, 407–417.
  • van de Wetering-Krebbers, S. F. M.; Jacobs, P. L.; Kemperman, G. J.; Spaans, E., Peeters, P. A. M.; Delbressine, L. P. C.; van Iersel, M. L. P. S. Metabolism and Excretion of Asenapine in Healthy Male Subjects. Drug Metabolism and Disposition 2011, 39 (4), 580–590.
  • Mali, N.; Karpe, M.; Kadam, V. A Review on Biological Matrices and Analytical Methods Used for Determination of Drug of Abuse. J. Appl. Pharmac. Sci. 2011, 1 (6), 58–65.
  • Barbosa, J.; Faria Carvalho, F.; Pedro, M.; Queirós, O.; Moreira, R.; Dinis-Oliveira, R. J. Hair as an Alternative Matrix in Bioanalysis. Bioanalysis 2013, 5 (8), 895–914.
  • Mandrioli, R.; Mercolini, L.; Cesta, R.; Fanali, S.; Amore, M.; Raggi, M. A. Analysis of the Second Generation Antidepressant Venlafaxine and Its Main Active Metabolite O-desmethylvenlafaxine in Human Plasma by HPLC with Spectrofluorimetric Detection. J. Chromatogr. B. 2007, 856, 88–94.
  • De Boer, T.; Meulman, E.; Meijering, H.; Wieling, J.; Dogterom, P.; Lass, H. Quantification of Asenapine and Three Metabolites in Human Plasma Using Liquid Chromatography–Tandem Mass Spectrometry with Automated Solid-phase Extraction: Application to a Phase I Clinical Trial with Asenapine in Healthy Male Subjects. Biomed. Chromatogr. 2011, 26 (2), 156–165.
  • De Boer, T.; Meulman, E,; Meijering, H.; Wieling, J.; Dogterom, P.; Lass, H. Development and Validation of Automated SPE-HPLC-MS/MS Methods for the Quantification of Asenapine, a New Antipsychotic Agent, and Its Two Major Metabolites in Human Urine. Biomed. Chromatogr. 2012, 25 (12), 1461–1463.
  • Ansermot, N.; Brawand-Amey, M.; Kottelat, A.; Eap, C. B. Fast Quantification of Ten Psychotropic Drugs and Metabolites in Human Plasma by Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry for Therapeutic Drug Monitoring. J. Chromatogr. A. 2013, 1292, 160–172.
  • Reddy, A. V. B.; Venugopal, N.; Madhavi, G. Simultaneous Determination of Asenapine and Valproic Acid in Human Plasma Using LC–MS/MS: Application of the Method to Support Pharmacokinetic Study. J. Pharmac. Anal. 2013, 3 (6), 394–401.
  • Aarelly, K.; Thimmaraju, M. K.; Nerella, R.; Allabotharam, S. Method Development and Validation of Asenapine in Bulk by RP-HPLC Method. J. Chem. Pharmac. Res. 2012, 4 (5), 2580–2584.

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