117
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Pharmacokinetics-pharmacodynamics and tissue distribution analysis of Low Polar extract of Xiaoyao Powder combined with rat model of chronic unpredictable mild stress

, , , , , , , & show all
Pages 173-183 | Received 11 Sep 2018, Accepted 31 Oct 2018, Published online: 15 Apr 2019

References

  • Schechter, L. E.; Ring, R. H.; Beyer, C. H.; Hughes, Z. A.; Khawaja, X.; Malberg, J. E.; Rosenzweig-Lipson, S. Innovative Approaches for the Development of Antidepressant Drugs: Current and Future Strategies. Neurotherapeutics. 2005, 2, 590–611.
  • Maes, M.; Yirmyia, R.; Noraberg, J.; Brene, F.; Hibbeln, J.; Perini, G.; Kubera, M.; Bob, P.; Lerer, B.; Maj, M. The Inflammatory & Neurodegenerative (I&ND) Hypothesis of Depression: Leads for Future Research and New Drug Developments in Depression. Metab. Brain Dis 2009, 24, 27–53.
  • Mizoguchi, K.; Ishige, A.; Aburada, M.; Tabira, T. Chronic Stress Attenuates Glucocorticoid Negative Feedback: involvement of the Prefrontal Cortex and Hippocampus. Neuroscience 2003, 119, 887–897.
  • Elhwuegi, A. S. Central Monoamines and Their Role in Major Depression. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2004, 28, 435–451.
  • Kwon, S.; Lee, B.; Kim, M.; Lee, H.; Park, H. J.; Hahm, H. J. Antidepressant-Like Effect of the Methanolic Extract from Bupleurum falcatum in the Tail Suspension Test. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2010, 34, 265–270.
  • Zhang, Y.; Gu, F.; Chen, J.; Dong, W. Chronic Antidepressant Administration Alleviates Frontal and Hippocampal BDNF Deficits in CUMS Rat. Brain Res. 2010, 1366, 141–148.
  • Ossowska, G.; Danilczuk, Z.; Klenk-Majewska, B.; Czajkowski, L.; Zebrowska-Łupina, I. Antidepressants in Chronic Unpredictable Mild Stress (CUMS)-Induced Deficit of Fighting Behavior. Pol. J. Pharmacol. 2004, 56, 305–312.
  • Sarko, J. Antidepressants, Old and New. A Review of Their Adverse Effects and Toxicity in Overdose. Emerg. Med. Clin. North Am. 2000, 18, 637–654.
  • Lu, A. P.; Bian, Z. X.; Chen, K. J. Bridging the Traditional Chinese Medicine Pattern Classification and Biomedical Disease Diagnosis with Systems Biology. Chin. J. Integr. Med. 2012, 18, 883–890.
  • Zhang, M. Z.; Zhang, Q. Y.; Cui, G. B. Clinical Study of XiaoYao-San in the Treatment of Depressive Neurosis. Shandong Univ. TCM. 1998, 22, 34–37.
  • Zhou, Y. Z.; Lu, L. L.; Li, Z. Y.; Gao, X. X.; Tian, J. S.; Zhang, L. Z.; Wu, B.; Qin, X. M. Antidepressant-like Effects of the Fractions of Xiaoyaosan on Rat Model of Chronic Unpredictable Mild Stress. J. Ethnopharmacol. 2011, 137, 236–244.
  • Liu, J. L.; Lan, Y.; Jie, C.; Guo, B. R.; Qin, X. M.; Gao, X. X. Preliminary Study on Serum Pharmacochemistry of Petroleum Ether Fraction in Ethanol Extract from Xiaoyao Powder Based on UPLC-PDA. Chin. Tradit. Herbal Drugs. 2013, 44, 2816–2822.
  • Gao, X. X.; Liang, M. L.; Fang, Y.; Zhao, F.; Tian, J. S.; Zhang, X.; Qin, X. M. Deciphering the Differential Effective and Toxic Responses of Bupleuri Radix following the Induction of Chronic Unpredictable Mild Stress and in Healthy Rats Based on Serum Metabolic Profiles. Front. Pharmacol. 2017, 8, 995.
  • Liu, J.; Fang, Y.; Yang, L.; Qin, X.; Du, G.; Gao, X. A Qualitative, and Quantitative Determination and Pharmacokinetic Study of Four Polyacetylenes from Radix Bupleuri by UPLC-PDA-MS. J. Pharmaceut. Biomed. 2015, 111, 257–265.
  • Song, J.; Lu, T.; Xie, L.; Liu, X. D. Analysis on Pharmacokinetics-Pharmacodynamics Correlation of Huanglian Jiedu Decoction. Chin. Tradit. Herbal Drugs 2011, 42, 2042–2046.
  • Ito, Y.; Harada, K.; Fushimi, K.; Kagawa, Y.; Oka, H.; Nakazawa, H.; Homma, R.; Kato, Y.; Yamada, S. Pharmacokinetic and Pharmacodynamic Analysis of Acetylcholinesterase Inhibition by Distigmine Bromide in Rats. Drug Metab. Pharmacok. 2010, 25, 254–261.
  • Jun-Fang, X. U.; Xiao-Gang, X. U.; Wang, M. H.; Shi, Y. G.; Jing, Z.; Wang, M. G.; Zhang, Y. Y. In Vitro Pharmacokinetics and Pharmacodynamics of Levofloxacin against Escherichia coli Expressing Plasmid-Mediated Quinolone Resistant Determinant qnra1. Chin. J. Infect. Chemother. 2008, 8, 250–254.
  • Cui, J. Preliminary Study on Pharmacokinetics of Antidepressant Effective Fraction from Xiaoyaosan Based on Serum Pharmacochemistry. Shanxi Uni 2012.
  • Lin, L.; Liu, J.; Zhang, Y.; Li, X.; Lin, C.; An, J. A PK/PD Data Processing Study on Chinese Formulation of Shuang-Shen-Tong-Guan Prescription. World Sci. Tech 2012, 14, 1583–1589.
  • Katz, R. J.; Roth, K. A.; Carroll, B. J. Acute and Chronic Stress Effects on Open Field Activity in the Rat: Implications for a Model of Depression. Neurosci. Biobehav. Rev. 1981, 5, 247–251.
  • Willner, P. Animal Models as Simulations of Depression. Trends Pharmacol. Sci. 1991, 12, 131–136.
  • Hong, D.; Qi, Y. L.; Zhang, Y. H.; Zhong, N. T.; Zheng, X. T.; Zhou, W.; Dong, Z. L. The Simple and Easy to Approach's Method to Building the CUMS Depression Model of Rats. Chin. Health Indust. 2011, 8, 3–4.
  • Yu, W. Y.; Lu, A. P.; Han, X. J. Exploration on Syndrome Differentiation Standardization of Chinese Medicine Diagnosis and Treatment. Chin. J. Integr. Tradit. West. Med. 2011, 31, 1419–1421.
  • Guo, B. R.; Yan, L.; Liu, J. L.; Qin, X. M.; Gao, X. X. Change of Serum Neurotransmitter Level in Depression Rats Induced by Chronic Unpredictable Stress. Chin. J. Pharmacol. Toxicol. 2013, 27, 138–144.
  • Guo, X. Q.; Tian, J. S.; Shi, B. Y.; Xing, J.; Jia, J. P.; Zhang, L. Z. 1H-NMR Metabonomics on Antidepression of Xiaoyao Powder Composed of Bupleurum Scorzonerifolium or Bupleurum Chinense. Chin. Tradit. Herbal Drugs 2012, 43, 2209–2216.
  • Zheng, X. Y.; Gao, X. X.; Liu, X. J.; Sun, H. F. Evaluation on Stress Animal Models of Depression Based on Metabonomics. Drug Eval. Res. 2010, 33, 175–179.
  • Li, X. Y.; Sun, J. G.; Zheng, Y. T.; Wu, X. L.; Li, Y. Y.; Xin, C. H.; Gu, S. J.; Wang, G. J. Protective Effect Study of Major Constituent in Total Panax Notoginsenoside on Rat Brain Microvessel Endothelial Cell (RBMEC) Damage Induced by H2O2. Chin. Pharmacol. Bull. 2007, 23, 1030–1034.
  • Li, Q. S.; Xi, H.; Han, G. Z.; Wang, C. Y.; Lü, L.; Zou, L. L. Integrated Pharmacokinetic Study of Multiple Effective Components of Tea Polyphenols and Its Correlation with anti-Free Radical Pharmacodynamics in Rats. Acta. Pharm. Sin. 2012, 47, 863–869.
  • Coppen, A.; Shaw, D. M.; Malleson, A. Changes in 5-Hydroxytryptophan Metabolism in Depression. Br. J. Psychiatry. 1965, 111, 105–107.
  • Duffey, K. C.; Shih, O.; Wong, N. L.; Drisdell, W. S.; Saykally, R. J.; Cohen, R. C. Evaporation Kinetics of Aqueous Acetic Acid Droplets: Effects of Soluble Organic Aerosol Components on the Mechanism of Water Evaporation. Phys. Chem. Chem. Phys. 2013, 15, 11634–11639.
  • Li, G. Y.; Ueki, H.; Yamamoto, Y.; Yamada, S. Association between the Scores on the General Health Questionnaire-28 and the Saliva Levels of 3-Methoxy-4-Hydroxyphenylglycol in Normal Volunteers. Biol. Psychol. 2006, 73, 209–211.
  • Wang, J.; Liu, Y.; Li, L.; Qi, Y.; Zhang, Y.; Li, L.; Teng, L.; Wang, D. Dopamine and Serotonin Contribute to Paecilomyces hepiali against Chronic Unpredictable Mild Stress Induced Depressive Behavior in Sprague Dawley Rats. Mol. Med. Rep. 2017, 16, 5675.
  • Zhao, F. Study on the Antidepressant Mechanism of the Petroleum Ether Fraction of Radix Bupleurum Based on Transcriptome. Shanxi Uni. 2018.
  • Su, G. Y. Antidepressant Effects of Xiaochaihutang and Its Regulation of Neurotransmitters, Neurotrophic Factors and Female Hormones. Shenyang Pharmaceut. Uni 2014.
  • Davidson, M.; Kahn, R. S.; Knott, P.; Kaminsky, R.; Cooper, M.; DuMont, K.; Apter, S.; Davis, K. L. Effects of Neuroleptic Treatment on Symptoms of Schizophrenia and Plasma Homovanillic Acid Concentrations. Arch. Gen. Psychiatry. 1991, 48, 910–913.
  • Dávila, R. Plasma HVA, Neuroleptics, and Dopaminergic Plasticity. Biol. Psychiatry. 1989, 25, 1–3.
  • Ballabh, P.; Braun, A.; Nedergaard, M. The Blood-Brain Barrier: An Overview Structure, Regulation, and Clinical Implications. Int. J. Cerebrovasc. Dis. 2004, 16, 1–13.
  • Chang, Y.; Pi, W.; Ang, W.; Liu, Y.; Li, C.; Zheng, J.; Xiong, L.; Yang, T.; Luo, Y. Synthesis and Evaluation of Amide Side-Chain Modified Agomelatine Analogues as Potential Antidepressant-Like Agents. Bioorg. Med. Chem. Let 2014, 24, 1672–1676.
  • Ang, W.; Chen, G.; Xiong, L.; Chang, Y.; Pi, W.; Liu, Y.; Li, C.; Zheng, J.; Zhou, L.; Yang, B.; et al. Synthesis and Biological Evaluation of Novel Naphthalene Compounds as Potential Antidepressant Agents. Eur. J. Med. Chem. 2014, 82, 263–273.
  • Guo, J.; Shang, E. X.; Duan, J. A.; Tang, Y.; Qian, D. Determination of Ligustilide in the Brains of Freely Moving Rats Using Microdialysis Coupled with Ultra Performance Liquid Chromatography/Mass Spectrometry. Fitoterapia 2011, 82, 441–445.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.