88
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Determination of ointments active ingredients and parabens by one analytical method – capillary GC with cool-on-column injection and FID detection

, &

References

  • Barkin, R. L. The Pharmacology of Topical Analgesics. Postgrad. Med. 2013, 125, 7–18. DOI: 10.1080/00325481.2013.1110566911.
  • Veloso, C.; Cardoso, C.; Vitorino, C. Topical Fixed-Dose Combinations: A Way of Progress for Pain Management? J. Pharm. Sci. 2021, 110, 3345–3361. DOI: 10.1016/j.xphs.2021.06.009.
  • Ministry of Health of Russian Federation. State Pharmacopeia of the Russian Federation. 14th ed.; Ministry of Health of Russian Federation: Moscow, 2018.
  • Shanley, A. Topical Formulation: Moving From Art to Science, APIs, Excipients, and Manufacturing 2016. Pharmaceut. Technol. 2016, 40, s26–s29.
  • Ioutsi, A. N.; Sarnitskaya, A. T.; Sumtsov, M. A. Simultaneous Determination of General Active Ingredients in a Topical Formulations by Gas Chromatography with Flame Ionization Detection (GC-FID). J. Chrom. Sci. 2023 (under revision).
  • Al-Halaseh, L. K.; Al-Adaileh, S.; Mbaideen, A.; Hajleh, M. N. A.; Al-Samydai, A.; Zakaraya, Z. Z.; Dayyih, W. A. Implication of Parabens in Cosmetics and Cosmeceuticals: Advantages and Limitations. J. Cosmet. Dermatol. 2022, 21, 3265–3271. DOI: 10.1111/jocd.14775.
  • Council of Europe. European Pharmacopoeia, 10th ed.; Council of Europe: Strasbourg, 2019.
  • United States Pharmacopeial Convention, United States Pharmacopeia 40 – National Formulary 35: Main Edition Plus Supplements 1 and 2; Deutscher Apotheker Verlag: Stuttgart, Germany, 2016.
  • Pauwels, J.; D'Autry, W.; Van den Bossche, L.; Dewever, C.; Forier, M.; Vandenwaeyenberg, S.; Wolfs, K.; Hoogmartens, J.; Van Schepdael, A.; Adams, E.; et al. Optimization and Validation of Liquid Chromatography and Headspace-Gas Chromatography Based Methods for the Quantitative Determination of Capsaicinoids, Salicylic Acid, Glycol Monosalicylate, Methyl Salicylate, Ethyl Salicylate, Camphor and 1-Menthol in a Topical Formulation. J. Pharm. Biomed. Anal. 2012, 60, 51–58. DOI: 10.1016/j.jpba.2011.10.024.
  • Barbero, G. F.; Liazid, A.; Ferreiro-González, M.; Palma, M.; Barroso, C. G. Fast Separation of Capsaicinoids from Peppers by Reversed Phase Ultra-Performance Liquid Chromatography: Comparation with Traditional High-Performance Liquid Chromatography Methods. Int. J. Food Prop. 2016, 19, 984–992. DOI: 10.1080/10942912.2015.1050673.
  • Adib, N. A. M.; Mandal, U. K.; Mohamed, F.; Chatterjee, B. Fast and Simple Gas Chromatographic Method for Simultaneous Estimation of Camphor, Menthol and Methyl Salicylate in Analgesic Ointment: Application in Stability Study. J. Pharm. Inv. 2017, 47, 275–285. DOI: 10.1007/s40005-017-0305-0.
  • Dhir, N. K.; Joshi, M.; Kaur, V. Improved Analytical Method for Estimation of Essential Oil in Drug Ointment through Rapid Static Chromatography Headspace for Quality Control Analysis. Asian J. Pharm. Clin. Res. 2018, 11, 290–294. DOI: 10.22159/ajpcr.2018.v11i5.23351.
  • Anyakudo, F.; Adams, E.; Van Schepdael, A. Simultaneous Analysis of Volatile and Semi-Volatile Components in a Topical Formulation by Gas Chromatography Using a Programmed Temperature Vaporization Inlet and Flame Ionization Detection. J. Pharm. Biomed. Anal. 2019, 171, 65–72. DOI: 10.1016/j.jpba.2019.03.057.
  • Katakam, L. N. R.; Ettaboina, S. K.; Dongala, T. A Simple and Rapid HPLC Method for Determination of Parabens and Their Degradation Products in Pharmaceutical Dosage Forms. Biomed. Chromatogr. 2021, 35, e5152. DOI: 10.1002/bmc.5152.
  • Osipov, A. S.; Popova, O. A.; Milkina, S. E.; Gretskaya, T. N.; Sulimenkova, A. I. The Use of a Chromatographic Column Packed with Amide Sorbent for the Analysis of Parabens. Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya. 2018, 8, 56–60. DOI: 10.30895/1991-2919-2018-8-1-56-60.
  • Anthi, P.; Zormpa, E.; Paloumpis, N.; Kabir, A.; Furton, K. G.; Roje, Ž.; Samanidou, V.; Vinković, V. I.; Panderi, I. Determination of Intact Parabens in the Human Plasma of Cancer and Non-Cancer Patients Using a Validated Fabric Phase Sorptive Extraction Reversed-Phase Liquid Chromatography Method with UV Detection. Molecules. 2021, 26, 1526–1545. DOI: 10.3390/molecules26061526.
  • Hang, Q.; Zhi, Y.; Bao, L.; Zheng, Y.; Wang, X.; Jiang, L.; Wu, Y. Determination of Six Parabens in Biological Samples by Magnetic Solid-Phase Extraction with Magnetic Mesoporous Carbon Adsorbent and UHPLC-MS/MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2021, 1179, 122817–122822. DOI: 10.1016/j.jchromb.2021.122817.
  • Rigkos, G.; Alampanos, V.; Kabir, A.; Furton, K. G.; Roje, Ž.; Vrček, I. V.; Panderi, I.; Samanidou, V. An Improved Fabric-Phase Sorptive Extraction Protocol for the Determination of Seven Parabens in Human Urine by HPLC-DAD. Biomed. Chromatogr. 2021, 35, e4974. DOI: 10.1002/bmc.4974.
  • Alshana, U.; Ertaş, N.; Göğer, N. G. Determination of Parabens in Human Milk and Other Food Samples by Capillary Electrophoresis After Dispersive Liquid-Liquid Microextraction With Back-Extraction. Food Chem. 2015, 181, 1–8. DOI: 10.1016/j.foodchem.2015.02.074.
  • Pieckowski, M.; Kowalski, P.; Bączek, T. Combination of Large Volume Sample Stacking With Polarity Switching and Cyclodextrin Electrokinetic Chromatography (LVSS-PS-CDEKC) for the Determination of Selected Preservatives in Pharmaceuticals. Talanta. 2020, 211, 120673–120678. DOI: 10.1016/j.talanta.2019.120673.
  • Uysal, U. D.; Güray, T. Determination of Parabens in Pharmaceutical and Cosmetic Products by Capillary Electrophoresis. J. Anal. Chem. 2008, 63, 982–986. DOI: 10.1134/S1061934808100109.
  • Dantas, M. S. R.; Lourenço, A. S.; Silva, A. C.; Bichinho, K. M.; Araujo, M. C. U. Simultaneous Determination of Methyl, Ethyl, Propyl, and Butyl Parabens in Sweetener Samples without Any Previous Pretreatment Using Square Wave Voltammetry and Multiway Calibration. Food Chem. 2021, 365, 130472–130480. DOI: 10.1016/j.foodchem.2021.130472.
  • Azzouz, A.; Colón, L. P.; Hejji, L.; Ballesteros, E. Determination of Alkylphenols, Phenylphenols, Bisphenol A, Parabens, Organophosphorus Pesticides and Triclosan in Different Cereal-Based Foodstuffs by Gas Chromatography-Mass Spectrometry. Anal. Bioanal. Chem. 2020, 412, 2621–2631. DOI: 10.1007/s00216-020-02491-1.
  • Levchyk, V. M.; Zui, M. F. Gas Chromatographic Determination of Parabens after Derivatization and Dispersive Microextraction. Fr. Ukr. J. Chem. 2015, 3, 72–79. DOI: 10.17721/fujcV3I2P72-79.
  • Wang, P. G.; Zhou, W. Rapid Determination of Parabens in Personal Care Products by Stable Isotope GC-MS/MS with Dynamic Selected Reaction Monitoring. J. Sep. Sci. 2013, 36, 1781–1787. DOI: 10.1002/jssc.201201098.
  • Ioutsi, A. N.; Sumtsov, M. A.; Artyushenko, D. A.; Bychenkov, D. V.; Blinov, A. N. Applicability of Capillary Gas-Liquid Chromatography for Determination of Parabens in Pharmaceutical Analysis. Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya. 2019, 9, 123–130. DOI: 10.30895/1991-2919-2019-9-2-123-130.
  • Leo, A.; Hansch, C.; Elkin, D. Partition Coefficients and Their Uses. Chem. Rev. 1971, 71, 525–616. DOI: 10.1021/cr60274a001.
  • Agilent Technologies. Agilent 7890 Series Gas Chromatograph. Maintaining Your GC. https://www.ecs.umass.edu/eve/facilities/equipment/Agilent6890/The%20Cool%20On-Column%20Inlet.pdf. (accessed Jan 23, 2023).
  • Sandra, P.; Badings, H. T. Sample Introduction in Capillary Gas Chromatography; A. Huethig: Heidelberg, 1985; Vol. 1, pp. 268.
  • Chauhan, J.; Darbre, A. Direct Injection on Capillary Columns for Gas Chromatography. J. High Resol. Chromatogr. 1981, 4, 260–265. DOI: 10.1002/jhrc.1240040603.
  • ICH. Validation of Analytical Procedures: Text and Methodology; International Conference on Harmonization Q2 (R1) IFPMA; ICH: Geneva, 2005.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.