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Original Articles

Determination of piroximone in Plasma and urine by high performance liquid chromatography

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Pages 2187-2197 | Received 01 Nov 1993, Accepted 14 Dec 1993, Published online: 17 Feb 2007

References

  • Haegele , K. D. , Belz , G. G. , Meinicke , T. T. and Schechter , P. J. 1986 . Pharmacokinetics of Piroximone (MDL 19.205) in healthy volunteers . Eur. J. Clin. Pharmacol. , 31 : 239
  • Confidential reports from Merrell Dow: protocol 099–014, protocols 099–008 and 099–009
  • Berg-Candolfi , M. , Borlakoglu , J. T. , Dulery , B. , Jehl , F. and Haegele , K. D. 1992 . Assessment of the biotransformation of the cardiotonic agent piroximone by high-performance liquid chromatography and gas chromatography-mass spectrometry . J. Chromatogr , 593 : 1
  • Houldsworth , C. Merrell Dow Strasbourg research team Actualized analytical method for pharmacokinetic studies. Personnal communication
  • Keely , F. J. , Theile , J. D. , Garteiz , D. A. , Weiner , D. L. and Okerholm , R. A. 1983 . Method of analysis of the new cardiotonic agent, MDL 19205, in plasma and urine and its application in a dog pharmacokinetic study . J. Chromatogr. , 278 : 379
  • Haegele , K. D. , Hinze , C. , Joder-Ohlenbusch , A. M. , Cremer , G. and Borlak , J. 1991 . Effects of a standardized meal on the pharmacokinetics of the new cardiotonic agent Piroximone . Arzneim.-Forsch./Drug Res. , 41 : 1225

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