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Original Articles

A High Performance Liquid Chromatographic Method for the Determination of Rapamycin (Sirolimus) in Rat Serum, Plasma, and Blood and in Monkey Serum

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Pages 1801-1808 | Received 14 Nov 1994, Accepted 01 Dec 1994, Published online: 23 Sep 2006

References

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  • Calne , R. Y. , Lim , S. , Somaan , A. , St , D. , Collier , J. , Pollard , S. G. and White , D. J. G. 1989 . Rapamycin for immunosuppression in organ allografting. The Lancet , : 227
  • Kimball , P. M. , Kerman , R. H. and Kahan , B. D. 1991 . Production of synergistic but nonidentical mechanisms of immunosuppression by rapamycin and cyclosporine. Transplantation , 51 : 486 – 90 .
  • Wang , C. P. , Chan , K. , Schiksnis , R. , Scatina , J. A. and Sisenwine , S. F. 1994 . High performance liquid chromatographic isolation, spectroscopic characterization and immunosuppressive activities of two rapamycin degradation products. J. Liquid Chrom. , 17 ( 16 ) : 3383 – 3392 .
  • Yatscoff , R. W. , Faraci , C. and Bolingbroke , P. 1992 . Measurement of rapamycin in whole blood using reverse-phase high-performance liquid chromatography. Ther. Drug Monit. , 14 : 138 – 141 .

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