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Original Articles

Kinetics of 5-(1-Phenyl-4-piperazinyl)methyl-2-amino-2-oxazoline Hydrolysis by High Performance Liquid Chromatography

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Pages 1379-1386 | Received 07 Aug 1997, Accepted 30 Aug 1997, Published online: 22 Aug 2006

REFERENCES

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  • Physical and spectral data for compound II: F(°C) 153 (Ethanol); Formula: C14H19N3O2; IR (KBr) v cm−1: 1730 (C=O), 3200 (NH); NMR 1H (CDCl3) δ ppm: 7.05 (m, 5H, Har), 5.10 (s, 1H, NH), 4.82 (m, 1H, 5-H), 3.63 (m, 2H, 4-H), 3.2 (m, 4H, CH2piperazine), 2.72 (m, 6H, CH2piperazine and NCH2); NMR 13C (CDCl3) δ ppm: 157.7 (C=O), 148.8, 129.1, 120.6, 116.2 (Cphenyl), 70.3 (C-5), 58.1 (CH2), 51.1 and 45.4 (Cpiperazine), 43.2 (C-4).
  • Chafetz , L. , Desaai , M. and Sukonik , L. 1994 . J. Pharm. Sci. , 83 : 1250 – 1252 .
  • Carstensen , J. T. , Franchini , M. and Ertel , K. 1992 . J. Pharm. Sci. , 81 : 303 – 308 .

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